SITES (ALPHABETICAL) HPV CS SITE SPECIFIC FACTOR
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1 SITES (ALPHABETICAL) HPV CS SITE SPECIFIC FACTOR Anus: Anal Canal; Anus, NOS; Other Parts of Rectum C21.0-C21.2, C21.8 C21.0 Anus, NOS (excludes skin of anus and perianal skin C44.5) C21.1 Anal canal C21.2 Cloacogenic zone C21.8 Overlapping lesion of rectum, anus and anal canal EpiglottisAnterior;Anterior Surface of Epiglottis C10.1 C10.1 Anterior surface of epiglottis Note: AJCC includes lingual (anterior) surface of epiglottis (C10.1) with larynx. SEER Extent of Disease included it with oropharynx Gum: GumLower; and Retromolar Area C03.1, C06.2 C03.1 Lower gum C06.2 Retromolar area GumOther; Gum, NOS C03.9 Gum, Upper C03.0 C03.0 Upper gum Hypopharynx Pyriform Sinus, Hypopharynx, Laryngopharynx C13.9 C12.9 Pyriform sinus C13.0 Postcricoid region C13.1 Hypopharyngeal aspect of aryepiglottic fold C13.2 Posterior wall of hypopharynx C13.8 Overlapping lesion of hypopharynx C13.9 Hypopharynx, NOS C12.9, C13.0-C13.2, C13.8- LarynxGlottic C32.0 C32.0 Glottis
2 LarynxOther; Larynx, Overlapping Lesion or Not Otherwise Specified 32.3, C32.8-C32.9 C32.3 Laryngeal cartilage C32.8 Overlapping lesion of larynx C32.9 Larynx, NOS LarynxSubglottic; Subglottic Larynx C32.2 C32.2 Subglottis LarynxSupraglottic; Supraglottic Larynx C32.1 C32.1 Supraglottis Note: Excludes Anterior Surface of Epiglottis - see separate schema (C10.1). Lip, Lower; Lip (Vermilion or Labial Mucosa) C00.1, C00.4, C00.6 C00.1 External lower lip C00.4 Mucosa of lower lip C00.6 Commissure of lip Note: AJCC includes labial mucosa (C00.4) with buccal mucosa (C06.0) LipUpper; Lip (Vermilion or Labial Mucosa) C00.0, C00.3 C00.0 External upper lip C00.3 Mucosa of upper lip Note: AJCC includes labial mucosa (C00.3) with buccal mucosa (C06.0) LipOther Lip (Vermilion or Labial Mucosa) C00.2, C00.5, C00.8-C00.9 C00.2 External lip, NOS C00.5 Mucosa of lip, NOS C00.8 Overlapping lesion of lip MiddleEar C30.1 C30.1 Middle ear Note 1: Laterality must be coded for this site. Note 2: AJCC does not define TNM staging for this site. MouthOther Other Mouth C05.8-C05.9, C06.8-C06.9 C05.8 Overlapping lesion of palate C05.9 Palate, NOS C06.8 Overlapping lesion 2
3 Nasal Cavity C30.0 C30.0 Nasal cavity (excludes nose, NOS C76.0) Note: Laterality must be coded Nasopharynx C11.0-C11.3, C11.8-C11.9 C11.0 Superior wall of nasopharynx C11.1 Posterior wall of nasopharynx C11.2 Lateral wall of nasopharynx C11.3 Anterior wall of nasopharynx C11.8 Overlapping lesion of nasopharynx C11.9 Nasopharynx, NOS Oropharynx Tonsil, Oropharynx [excl. Malignant Melanoma] C09.0-C09.1, C09.8-C09.9, C10.0, C10.2-C10.4, C10.8-C10.9 C09.0 Tonsillar fossa C09.1 Tonsillar pillar C09.8 Overlapping lesion of tonsil C09.9 Tonsil, NOS (excludes lingual tonsil C02.4) C10.0 Vallecula C10.2 Lateral wall of oropharynx C10.3 Posterior wall of oropharynx C10.4 Branchial cleft (site of neoplasm) C10.8 Overlapping lesion of oropharynx C10.9 Oropharynx, NOS Note 1: Laterality must be coded for C09.0, C09.1, C09.8, and C09.9. Palate Hard C05.0 C05.0 Hard palate PalateSoft Soft Palate, Uvula C05.1-C05.2 C05.1 Soft Palate, NOS C05.2 Uvula Note 1: AJCC includes inferior surface of the soft palate (C05.1) and uvula (C05.2) with oropharynx (C09._, C10._). Note 2: Soft palate excludes nasopharyngeal (superior) surface of soft palate (C11.3). Penis [excl Malignant Melanoma, Merkel Cell Carcinoma, Kaposi Sarcoma, Mycosis Fungoides, Sezary Disease and Other Lymphomas] C60.0-C60.2, C60.8-C60.9 C60.0 Prepuce 3
4 C60.1 Glans penis C60.2 Body of penis C60.8 Overlapping lesion of penis C60.9 Penis, NOS Note 1: This schema is NOT used for Malignant Melanoma, Merkel Cell Carcinoma of Penis, Kaposi Sarcoma, Mycosis Fungoides, Sezary Disease, or Other Lymphomas. Each of these diseases has a separate schema. Note 2: Primary carcinoma of the urethra is to be coded C68.0 and assigned Collaborative Stage codes according to the urethra scheme. PharyngealTonsil PharyngealTonsil [excl. Malignant Melanoma] C11.1 C11.1 Posterior wall of nasopharynx Site-Specific Factor 25 PharynxOther Pharynx, NOS, and Overlapping Lesions of Lip, Oral Cavity, and Pharynx C14.0, C14.2, C14.8 C14.0 Pharynx, NOS C14.2 Waldeyer ring C14.8 Overlapping lesion of lip, oral cavity Note: AJCC does not define TNM staging for this site. Pyriform Sinus, Hypopharynx, Laryngopharynx C12.9, C13.0-C13.2, C13.8-C13.9 C12.9 Pyriform sinus C13.0 Postcricoid region C13.1 Hypopharyngeal aspect of aryepiglottic fold C13.2 Posterior wall of hypopharynx C13.8 Overlapping lesion of hypopharynx C13.9 Hypopharynx, NOS Retromolar gingiva (trigone) C03.1, C06.2 C03.1 Lower gum C06.2 Retromolar area SinusEthmoid C31.1 C31.1 Ethmoid sinus SinusMaxillary Maxillary Sinus C31.0 C31.0 Maxillary sinus Note: Laterality must be coded for this site 4
5 SinusOther Accessory (Paranasal) Sinuses C31.2-C31.3, C31.8-C31.9 C31.2 Frontal sinus C31.3 Sphenoid sinus C31.8 Overlapping lesion of accessory sinuses C31.9 Accessory sinus, NOS Note 1: Laterality must be coded for Frontal sinus, C31.2 Note 2: AJCC does not define TNM staging for this site. TongueAnterior Anterior 2/3 of Tongue, Tip, Border, and Tongue, NOS C02.0-C02.3, C02.8- C02.9 C02.0 Dorsal surface of tongue, NOS C02.1 Border of tongue C02.2 Ventral surface of tongue, NOS C02.3 Anterior 2/3 of tongue, NOS C02.8 Overlapping lesion of tongue C02.9 Tongue, NOS TongueBase Base of Tongue, Lingual Tonsil C01.9, C02.4 C01.9 Base of tongue, NOS C02.4 Lingual tonsil Note: AJCC includes base of tongue 5
6 Sample: Data Collection Schema for Head/Neck Cancers and HPV Collaborative Stage for TNM 7 - Revised 10/12/2009 [ Schema ] Oropharynx CS Site-Specific Factor 10 HPV (Human Papilloma Virus) Status Code 000 Description HPV test negative; not positive for any HPV types Negative, NOS 010 LOW RISK positive (all positive type(s) are low risk) HIGH RISK positive, specified type(s) other than types 16 or 18, HIGH RISK positive for HPV 16 WITHOUT positive results for HPV 18 or positivity of HPV 18 unknown, WITH or WITHOUT positive results for other high-risk types, 040 HIGH RISK positive for HPV 18 WITHOUT positive results for HPV 16 or positivity of HPV 16 unknown, WITH or WITHOUT positive results for other high-risk types, 050 HIGH RISK positive for HPV 16 AND HPV 18, WITH or WITHOUT positive results for other high-risk types, 060 HIGH RISK positive, NOS, type(s) not specified 070 Positive, NOS, risk and type(s) not stated 988 Not applicable: Information not collected for this case 997 Test ordered, results not in chart Test not done (test was not ordered and was not performed), including no pathologic specimen available for HPV testing Unknown or no information Not documented in patient record 6
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