EVALUATION OF MULLIGAN S TECHNIQUE FOR ADHESIVE CAPSULITIS OF THE SHOULDER

Size: px
Start display at page:

Download "EVALUATION OF MULLIGAN S TECHNIQUE FOR ADHESIVE CAPSULITIS OF THE SHOULDER"

Transcription

1 J Rehbil Med 2013; 45: ORIGINAL REPORT EVALUATION OF MULLIGAN S TECHNIQUE FOR ADHESIVE CAPSULITIS OF THE SHOULDER Gokhn Doner, PT, MSc 1, Zeynep Guven, MD 2, Ayçe Atly, MD 2 nd Reyhn Celiker, MD 2 From the 1 Özel Acdemic Hospitl, Nuh Kuyusu Cd Bğlrbşı, Üsküdr nd 2 Acibdem University, Fculty of Medicine, Deprtment of Physicl Medicine nd Rehbilittion, İstnbul, Turkey Objective: To evlute Mullign s technique for relieving pin nd improving functionl cpcity of the shoulder in ptients with dhesive cpsulitis in the stiffness phse. Design: Rndomized controlled study. Methods: A totl of 40 subjects were rndomly llocted into 2 groups: (i) group 1 (n = 20) were treted with hot pck, trnscutneous electricl nerve stimultion, nd pssive stretching exercises; (ii) group 2 (n = 20) were treted with hot pck, trnscutneous electricl nerve stimultion nd Mullign s technique. Mullign s technique combines the sustined ppliction of mnul gliding force to joint, with the im of repositioning bone positionl fults while enbling concurrent physiologicl (osteo-kinemtic) motion of the joint. All cses were evluted using visul nlogue scles for pin, pssive nd ctive rnge of motion, Constnt score, Shoulder Disbility Questionnire, nd ptient nd therpist stisfction t bseline, fter completion of tretment sessions nd t the end of 3 months of follow-up. Results: Mrked improvement ws noted in both groups fter completion of tretment sessions nd t the third month of follow-up compred with bseline. The improvements in outcome mesures, nmely pin, rnge of motion, shoulder scores, nd ptient nd physiotherpist stisfction, were significntly greter in subjects in group 2, who were treted with Mullign s technique. Conclusion: Mullign s technique nd pssive stretching exercises re both effective in reducing pin, nd restoring rnge of motion nd function. However, compred with stretching exercises, Mullign s technique led to better improvements in terms of pin, rnge of motion, shoulder scores, nd ptient nd physiotherpist stisfction. Key words: dhesive cpsulitis; hot pck; Mullign s technique; shoulder pin. J Rehbil Med 2013; 45: Correspondence ddress: Zeynep Guven, Gülsuyu Mh. Fevzi Çkmk Cddesi, Divn sokk No. 1, Mltepe, Istnbul. E- mil: zeynep.guven@cibdem.edu.tr Submitted Mrch 3, 2012; ccepted July 4, 2012 INTRODUCTION Adhesive cpsulitis leds to pin nd functionl disbility s result of the limited rnge of motion (ROM) of the shoulder girdle. Although the nturl history of dhesive cpsulitis is not completely understood (1), ptients experience the following stges of the condition; freezing or pinful stge, followed by stiffness, frozen or trnsitionl phse, nd finlly thwing phse, chrcterized by incresed ROM (2, 3). Tretments dvocted for dhesive cpsulitis include rehbilittion s the initil conservtive mesure, nti-inflmmtory drugs, intrrticulr corticosteroids, cpsulr distension injections, nd surgicl interventions in refrctory cses. Vrious tretments, including mobiliztion nd mnipultion techniques, hve been dvocted for restortion of pin-free stte nd norml use of the upper extremity. Mnul nd mnipultive tretment options for this condition include high-velocity, low mplitude mnipultion, end-rnge mobiliztion, mid-rnge mobiliztion, nd mobiliztion with movement of the shoulder only nd/ or of the shoulder girdle (4). The rehbilittive interventions performed depend on the institution. The optiml use of common physicl therpies nd the frequency nd timing of session criteri hve not yet been estblished (5). Mullign s technique for peripherl joints combines sustined mnul ppliction of gliding force to joint, with the im of repositioning bone positionl fults with concurrent physiologicl (osteo-kinemtic) motion of the joint, either performed ctively by the subject or pssively by the therpist (6). It hs been shown tht Mullign s technique cn produce concurrent hypolgesic effects during nd following its ppliction, s well s ltering sympthetic nervous system function (7). The im of this study ws to investigte the effects of Mullign s technique for relieving pin nd improving the functionl cpcity of the shoulder in ptients with dhesive cpsulitis in the stiffness phse compred with ptients treted with conventionl pssive stretching exercises. MATERIAL AND METHODS Subjects A totl of 40 subjects with shoulder pin of t lest 3 months durtion, dignosed s dhesive cpsulitis in the stiffness phse ccording to physicl exmintion in the outptient clinic of the Physicl Medicine nd Rehbilittion Deprtment were recruited. Adhesive cpsulitis ws defined s 50% loss of pssive movement of the shoulder joint reltive to the non-ffected side, in 1 or more of 3 movement directions (i.e. bduction in the frontl plne, forwrd flexion, or externl rottion in 0º of bduction) similr to Vermeulen et l. (8). They were exmined by the sme physitrist for their suitbility for inclusion in the study 2013 The Authors. doi: / Journl Compiltion 2013 Foundtion of Rehbilittion Informtion. ISSN J Rehbil Med 45

2 88 G. Doner et l. nd rdiologicl exmintions were crried out ccordingly. The study ws pproved by the ethics committee (No: MAR-YC ). Exclusion criteri were: previous tretments other thn mediction, contrindictions for physicl therpy (infections or mlignncies in the shoulder region, severe hypertension, severe crdic filure, uncontrolled dibetes mellitus, neurologicl deficits, skin lesions involving the shoulder region, post-trumtic cses). Ptients with coexisting neck pin nd rdiculopthies were lso excluded. Study design A totl of 40 subjects were rndomized using tble of rndom numbers. They were llocted into two groups. Group 1 (n = 20) ws treted with hot pck (HP), trnscutneous electricl nerve stimultion (TENS), nd pssive stretching exercises in 4 directions (flexion, bduction, internl nd externl rottion). Group 2 (n = 20) received HP, TENS nd Mullign s technique. The ptients were followed for 3 months. Tretment procedures Hot pcks were used to deliver superficil heting. HPs were used before stretching or Mullign s technique to increse the extensibility of the collgen. The temperture ws djusted to comfortble level for the ptients throughout the tretment. Ech tretment session lsted 20 min. After ppliction of HP, stretching ws pplied. Conventionl pssive stretching included bduction in the scpulr plne, flexion with the ptient in the supine position, nd rottions during bduction (the degree of bduction ws incresed ccording to the ptient s progress nd tolernce level). Ech stretch ws mintined for 30 s, with 15 s rest between stretches. TENS sessions lsted 20 min. The frequency of TENS ws set to 100 Hz nd pulse durtion ws set to pproximtely ms. Ptients remined in seted position with their shoulders in neutrl position. The intensity of the current ws incresed to the point of observtion of no contrctions, but with light tingling senstion, while ensuring the ptient ws comfortble. Group 2 received HP, TENS nd Mullign s technique. Mullign s technique ws pplied in flexion, elevtion nd internl rottion. Three sets of 10 repetitions were pplied, with rest intervl of 30 s between ech set. Ptients were treted for 5 dys per week for 3 weeks. All cses were informed bout dily cre for the shoulders. They were dvised to use the ffected shoulder in dily ctivities whenever possible. All ptients were instructed to perform pendulum exercises nd ctive shoulder exercises twice dy. In previous studies concerning mnul nd mnipultive tretments for dhesive cpsulitis of the shoulder pendulum exercises were lso included in ddition to specific interventions (8, 9). All cses were evluted using visul nlogue scle (VAS) for pin, pssive nd ctive ROM, Constnt score, Shoulder Disbility Questionnire (SDQ), nd ptient nd therpist stisfction, t bseline, fter completion of tretment sessions nd the end of 3 months of follow-up. Outcome mesures The tretment outcomes used in this study were: VAS, goniometric ROM exmintion, Constnt score, SDQ, nd stisfction of the ptient nd the physiotherpist. Pin during rest nd during movement ws evluted seprtely using 10-cm horizontl VAS line. nd pssive shoulder ROM during flexion, bduction, internl nd externl rottion were noted for both shoulders. Shoulder flexion nd bduction were noted s 0 180º nd internl nd externl rottion s 0 90º. The Constnt score hs the benefits of including vrious mesures, including pin, functionl ssessment, ROM nd strength mesures. Constnt score hs been widely used for the ssessment of vrious shoulder disorders. It hs been specificlly vlidted for dhesive cpsulitis nd is currently the gold stndrd (10, 11). This mesure hs 100-point scoring system, with 100 points being the best score (12). SDQ covers 16 items iming to evlute functionl limittion in ptients with shoulder disorders. SDQ is dvntgeous for use in physiotherpy units, since the items of the SDQ were generted from the routine history of the ptients with shoulder disorders in physiotherpy (13). The Turkish version of the SDQ hs been shown to be relible nd vlid (14). It hs been demonstrted previously tht SDQ is useful instrument to ssess functionl disbility in longitudinl studies (15). In the SDQ, the best score is 0, while the worst is 100 (13). Ptient nd physiotherpist stisfction ws grded s 1 = worse, 2 = sme, 3 = slightly better, 4 = better, nd 5 = full recovery. Dt nlysis Sttisticl nlysis ws performed with NCSS 2007&PASS 2008 Sttisticl Softwre. In ddition to descriptive sttistics for vribles with norml distribution we used Student s t-test for group comprison, vrince nlysis for repeted mesures, nd pired smple t-test for intrgroup comprisons. Vribles tht were not normlly distributed were nlysed with Mnn-Whitney U test for group comprison, Friedmn test for repeted mesures nd Wilcoxon test for intrgroup comprisons. For vribles tht were not normlly distributed, Friedmn test ws used for repeted mesures, Wilcoxon sign test ws used for intrgroup comprisons. For ordinl vribles χ 2 test, Fischer s exct χ 2 test nd McNemr test were pplied. The confidence intervl ws ccepted s 95% nd p-vlue less thn 0.05 ws tken s sttisticlly significnt. RESULTS A totl of 40 ptients; 31 (77.5%) femles nd 9 (22.5%) mles, ge rnge yers, were included in the study. The men ge of the study group ws yers (stndrd devition (SD) 8.77). The tretment groups were similr in terms of ge, sex, involved shoulder, dominnt shoulder nd ccompnying medicl diseses (p > 0.05) (Tble I). Pin In both groups, ptients improved significntly in terms of pin t rest nd during ctivity between bseline, fter tretment nd follow-up t third month (p < 0.01). Pin t rest ws similr between the tretment groups t bseline nd fter tretment Tble I. Bseline chrcteristics of the study group Chrcteristics Group 1 p-vlue Age, yers, men (SD) c (8.57) (9.17) Sex, n (%) d Femle 18 (90.0) 13 (65.0) Mle 2 (10.0) 7 (35.0) Affected shoulder, n (%) d Right Left 5 (25.0) 15 (75.0) 10 (50.0) 10 (50.0) Dominnt shoulder, n (%) d Right Left Accompnying medicl disorder, n (%) d Present Absent 19 (95.0) 1 (5.0) 13 (65.0) 7 (35.0) 20 (100.0) 0 (0) 15 (75.0) 5 (25.0) Group 1: hot pck, trnscutneous electricl nerve stimultion (TENS), stretching; b Group 2: hot pck, TENS, Mullign s technique; c Student s t-test; d χ 2 or Fischer s exct test. SD: stndrd devition. J Rehbil Med 45

3 Mullign s technique for dhesive cpsulitis 89 (p > 0.05). However, ptients in group 2 reported significntly lower pin t rest compred with group 1 t the third month (p < 0.05). In ddition, ptients in group 2 reported significntly less pin during ctivity fter tretment nd t the third month (p < 0.01). VAS scores re summrized in Tble II. Goniometric rnge of motion In both groups, ROM during flexion, bduction, internl nd externl rottion improved significntly between bseline, fter tretment nd follow-up t the third month (p = 0.001). Ptients in group 2 hd significntly higher ctive nd pssive flexion fter tretment nd t the third month (p < 0.01), ctive nd pssive bduction fter tretment nd the third month (p < 0.05), ctive nd pssive internl rottion fter tretment nd the third month (p < 0.05). Ptients in both groups hd similr ctive nd pssive externl rottion fter tretment (p > 0.05), but ptients in group 2 hd higher externl rottion t the third month compred with group 1 (p < 0.05). Goniometric ROM mesurements re summrized in Tble III. Constnt score In both groups, Constnt scores improved significntly between bseline, fter tretment nd follow-up t third month (p = 0.001). Ptients in group 2 hd higher Constnt scores compred with group 1 fter tretment nd t the third month (p < 0.01) (Tble IV). Shoulder Disbility Questionnire In both groups the SDQ scores improved significntly between bseline, fter tretment nd follow-up t the third month (p = 0.001). Ptients in group 2 hd lower disbility scores fter tretment nd t the third month (Tble V). Ptient stisfction In both groups ptients reported better results t the third month compred with fter tretment (p < 0.05 nd p < 0.01, Tble II. Pin mesurements t bseline, fter tretment nd t the third month for both tretment groups Pin Group 1 p-vlue c Pin t rest Bseline 3.43 (1.74) 3.24 (2.19) After tretment 1.14 (1.22) 0.75 (1.18) Third month 0.44 (0.63) 0.20 (0.82) 0.018* Pin during ctivity Bseline 6.93 (1.39) 7.49 (1.57) After tretment 3.57 (1.18) 2.34 (2.15) 0.005** Third month 2.21 (1.45) 1.03 (1.84) 0.003** Group 1: hot pck, trnscutneous electricl nerve stimultion (TENS), stretching; b Group 2: hot pck, TENS, Mullign s technique; c Mnn Whitney U test; d Friedmn test. SD: stndrd devition. respectively). Ptients in group 2 reported significntly better results fter tretment nd t the third month compred with group 1 (p = 0.001) (Tble VI). Physiotherpist stisfction In both groups physiotherpists reported better results t the third month compred with fter tretment (p < 0.01). Ptients in group 2 reported significntly better results fter tretment Tble III. Rnge of motion (ROM) mesurements t bseline, fter tretment nd t the third month for both tretment groups ROM Group 1 p-vlue c Flexion Bseline (19.30) (17.90) After tretment (15.76) (13.30) 0.004** Third month (18.53) (8.41) 0.001** Pssive Bseline (19.06) (17.56) After tretment (16.35) (11.70) 0.008** Third month (17.13) (4.41) 0.013* Aduction Bseline (21.17) (26.71) After tretment (25.95) (30.65) 0.032* Third month (28.26) (21.73) 0.001** Pssive Bseline (22.17) (19.89) After tretment (24.90) (27.48) 0.024* Third month (26.97) (25.39) 0.024* Internl rottion Bseline (20.70) (11.75) After tretment (19.49) (15.85) 0.029* Third month (18.01) (7.45) 0.001** Pssive Bseline (19.06) (10.93) After tretment (16.95) (12.55) 0.032* Third month (14.46) (3.08) 0.002** Externl rottion Bseline (17.20) (12.55) After tretment (24.65) (23.76) Third month (24.89) (18.88) 0.041* Pssive Bseline (17.16) (12.98) After tretment (23.09) (21.37) Third month (22.70) (15.20) Group 1: hot pck, trnscutneous electricl nerve stimultion (TENS), stretching; b Group 2: hot pck, TENS, Mullign s technique; c Student s t-test; d repeted mesures nlysis of vrince. SD: stndrd devition. J Rehbil Med 45

4 90 G. Doner et l. Tble IV. Constnt scores t bseline, fter tretment nd t third month for both tretment groups Constnt scores Group 1 nd t the third month compred with group 1 (p = 0.001) (Tble VI). DISCUSSION This study compred the effects of two tretment strtegies; Mullign s technique nd stretching exercises. It ws demonstrted tht both strtegies re effective in reducing pin nd restoring ROM nd function in ptients with dhesive cpsulitis in the stiffness phse. Compred with stretching exercises, Mullign s technique led to better improvements in terms of pin, ROM, shoulder scores nd ptient nd physiotherpist stisfction. This is the first study to demonstrte tht the 3-month outcome of the Mullign s technique is fvourble compred with conventionl stretching exercises in ddition to the immedite effects of the tretment. Mullign s technique ws chosen for this study becuse it hs the dvntge of incresing ROM in ddition to providing nlgesi. Mullign s technique ws compred with stretching becuse stretching exercises re the minsty of exercises in joint limittions; however, in contrst to Mullign s technique they lck n nlgesic effect. Mnul therpy interventions, usully combined with physicl therpy, hve been shown previously to result fvourbly in terms of pin, ROM nd function in vrious studies (8, 16, 17). We imed to investigte the effects of specific intervention becuse it becomes difficult to drw conclusions due to multiple interventions. We chose stretching exercises for comprison becuse Griggs et l. (18) hve previously demonstrted tht the vst mjority of ptients who hve idiopthic Tble V. Shoulder disbility scores t bseline, fter tretment nd t third month for both tretment groups Group 1 p-vlue c Bseline (17.39) (17.39) After tretment (18.32) (11.70) 0.001** Third month (18.96) (3.56) 0.001** Group 1: hot pck, trnscutneous electricl nerve stimultion (TENS), stretching; b Group 2: hot pck, TENS, Mullign s technique; c Student s t-test; d repeted mesures nlysis of vrince (ANOVA). SD: stndrd devition. Bseline (12.22) (21.32) After tretment (29.84) (26.26) 0.001** Third month (28.33) 8.02 (22.07) 0.003** **p < Group 1: hot pck, trnscutneous electricl nerve stimultion (TENS), stretching; b Group 2: hot pck, TENS, Mullign s technique; c Mnn Whitney U test; d Friedmn test. SD: stndrd devition. p c Tble VI. Ptient nd physiotherpist stisfction t bseline, fter tretment nd t third month for both tretment groups Group 1 n (%) n (%) p-vlue c Ptient stisfction After tretment Sme 0 (0) 0 (0) Slightly better 12 (40.0) 1 (5.0) Better 8 (40.0) 17 (85.0) Full recovery 0 (0) 2 (10) Third month Sme 0 (0) 0 (0) Slightly better 8 (40.0) 0 (0) Better 9 (45.0) 7 (35.0) Full recovery 3 (15.0) 13 (65.0) Physiotherpist stisfction After tretment Sme 0 (0) 0 (0) Slightly better 13 (65.0) 2 (10.0) Better 7 (35.0) 15 (75.0) Full recovery 0 (0) 3 (15.0) Third month Sme 0 (0) 0 (0) Slightly better 6 (30.0) 0 (0) Better 12 (60.0) 7 (35.0) Full recovery 2 (10.0) 13 (65.0) *p < Group 1: hot pck, trnscutneous electricl nerve stimultion (TENS), stretching; b Group 2: hot pck, TENS, Mullign s technique; c χ 2 test. dhesive cpsulitis cn be treted successfully with specific 4-direction shoulder stretching progrmme. In our study, it ws not possible to include shm group since ptients would esily differentite. Scringe et l.(19) hve previously used the Mullign s technique in ddition to chiroprctic mnipultions of the spine for golfer with chronic shoulder, rm nd neck pin. The uthors hve followed the ptient for 29 weeks; however, they used multiple techniques, which mde it difficult to delinete the specific effects of certin tretment. In our study we included meticulously chosen subset of ptients with shoulder pin only, nd investigted the effect of the technique by comprison with stretching exercises. We combined both of the interventions, Mullign s technique nd stretching exercises, with HP nd TENS to eliminte pin. We did not include multiple techniques, which would hve mde it difficult to drw conclusion bout the effect of the prticulr tretment per se. Pungmli et l. hve previously demonstrted the hypolgesic effect of Mullign s technique for lterl epicondyllgi (7). In ddition, Teys et l. (20) stted tht cliniclly meningful improvements in both ROM nd pressure pin threshold occur immeditely fter the ppliction of Mullign s technique in the pin-limited shoulder. This study hs certin limittions. Since Mullign s technique is hnds-on tretment it is not possible to perform J Rehbil Med 45

5 Mullign s technique for dhesive cpsulitis 91 the study in blinded mnner. And, gin, since the study is bout mnul tretment, the therpy is pplied by the sme experienced therpist. It ws not ethicl to use shm group; thus the control group ws lso treted with conventionl stretching exercises. This study hs estblished the immedite nd 3-month effects of Mullign s technique in ptients with dhesive cpsulitis. The results show tht tht Mullign s technique offers dvntges over conventionl stretching exercises. In our study we were ble to nlyse the ptients with dhesive cpsulitis in the stiffness phse from vrious spects, including pin, ROM, disbility scores, nd ptient nd physiotherpist stisfction, fter completion of the therpy sessions nd in the subsequent 3-month period. The results show tht Mullign s technique offers dvntges tht re sustined fter completion of the tretment. The uthors declre no conflicts of interest. REFERENCES 1. Hrris JD, Griesser MJ, Copeln A, Jones GL. Tretment of dhesive cpsulitis with intr-rticulr hyluronte: systemtic review. Int J Shoulder Surg 2011; 5: Leung MS, Cheing GL. Effects of deep nd superficil heting in the mngement of frozen shoulder. J Rehbil Med 2008; 40: Mnske RC, Prohsk D. Dignosis nd mngement of dhesive cpsulitis. Curr Rev Musculoskelet Med 2008; 1: Brntinghm JW, Css TK, Bonnefin D, Jensen M, Globe G, Hicks M, et l. Mnipultive therpy for shoulder pin nd disorders: expnsion of systemtic review. J Mnipultive Physiol Ther 2011; 34: Nicholson GC. The effects of pssive joint mobiliztion on pin nd hypomobility ssocited with dhesive cpsulitis of the shoulder. J Orthop Sports Phys Ther 1985; 6: Yng JL, Chng CW, Chen SY, Wng SF, Lin JJ. Mobiliztion techniques in subjects with frozen shoulder syndrome: rndomized multiple-tretment tril. Phys Ther 2007; 87: Pungmli A, O Lery S, Souvlis T, Vicenzino B. Hypolgesic nd sympthoexcittory effects of mobiliztion with movement for lterl epicondyllgi. Phys Ther 2003; 83: Vermeulen HM, Rozing PM, Obermnn WR, le Cessie S, Vliet Vlielnd TP. Comprison of high-grde nd low-grde mobiliztion techniques in the mngement of dhesive cpsulitis of the shoulder: rndomized controlled tril. Phys Ther 2006; 86: Rinbow DM, Weston JP, Brntinghm JW, Globe G, Lee F. A prospective, clinicl tril compring chiroprctic mnipultion nd exercise therpy vs. chiroprctic mobiliztion nd exercise therpy for tretment of ptients suffering from dhesive cpsulitis/frozen shoulder. J Am Chiropr Assoc 2008; 45: Othmn A, Tylor G. Is the constnt score relible in ssessing ptients with frozen shoulder? 60 shoulders scored 3 yers fter mnipultion under nesthesi. Act Orthop Scnd 2004; 75: Dupeyron A, Gelis A, Sblyrolles P, Bousquet PJ, Juli M, Herisson C, et l. Heterogeneous ssessment of shoulder disorders: vlidtion of the Stndrdized Index of Shoulder Function. J Rehbil Med 2010; 42: Wright RW, Bumgrten KM. Shoulder outcomes mesures. J Am Acd Orthop Surg 2010; 18: Vn der Heijden GJ, Leffers P, Bouter LM. Shoulder Disbility Questionnire design nd responsiveness of functionl sttus mesure. J Clin Epidemiol 2000; 53: Ozshın M, Akgun K, Akts I, Kurtis Y. Adpttion of the shoulder disbility questionnire to the Turkish popultion, its relibility nd vlidity. Int J Rehbil Res 2008; 31: vn der Windt DA, vn der Heijden GJ, de Winter AF, Koes BW, Deville W, Bouter LM. The responsiveness of the Shoulder Disbility Questionnire. Ann Rheum Dis 1998; 57: Plczek JD, Roubl PJ, Freemn DC, Kulig K, Nsser S, Pgett BT. Long-term effectiveness of trnsltionl mnipultion for dhesive cpsulitis. Clin Orthop Relt Res 1998; 356: Roubl PJ, Dobritt D, Plczek JD. Glenohumerl gliding mnipultion following intersclene brchil plexus block in ptients with dhesive cpsulitis. J Orthop Sports Phys Ther 1996; 24; Griggs SM, Ahn A, Green A. Idiopthic dhesive cpsulitis. A prospective functionl outcome study of nonopertive tretment. J Bone Joint Surg Am 2000; 82-A: Scringe J, Kwok C, Studt T. Improved shoulder function fter using spinl mobiliztion with rm movement in 50 yer old golfer with shoulder, rm nd neck pin. Topics in Clinicl Chiroprctic 2002; 9: Teys P, Bisset L, Vicenzino B. The initil effects of Mullign s mobiliztion with movement technique on rnge of movement nd pressure pin threshold in pin-limited shoulders. Mn Ther 2008; 13: J Rehbil Med 45

Clinical Study Report Synopsis Drug Substance Naloxegol Study Code D3820C00018 Edition Number 1 Date 01 February 2013 EudraCT Number

Clinical Study Report Synopsis Drug Substance Naloxegol Study Code D3820C00018 Edition Number 1 Date 01 February 2013 EudraCT Number EudrCT Number 2012-001531-31 A Phse I, Rndomised, Open-lbel, 3-wy Cross-over Study in Helthy Volunteers to Demonstrte the Bioequivlence of the Nloxegol 25 mg Commercil nd Phse III Formultions nd to Assess

More information

Supplementary Online Content

Supplementary Online Content Supplementry Online Content Zulmn DM, Pl Chee C, Ezeji-Okoye SC, et l. Effect of n intensive outptient progrm to ugment primry cre for high-need Veterns Affirs ptients: rndomized clinicl tril. JAMA Intern

More information

Assessment of Depression in Multiple Sclerosis. Validity of Including Somatic Items on the Beck Depression Inventory II

Assessment of Depression in Multiple Sclerosis. Validity of Including Somatic Items on the Beck Depression Inventory II Assessment of Depression in Multiple Sclerosis Vlidity of Including Somtic Items on the Beck Depression Inventory II Peggy Crwford, PhD; Noh J. Webster, MA Signs nd symptoms of multiple sclerosis (MS)

More information

Evaluation of a task-oriented client-centered upper extremity skilled performance training module in persons with tetraplegia

Evaluation of a task-oriented client-centered upper extremity skilled performance training module in persons with tetraplegia (2011) 49, 1049 1054 & 2011 Interntionl Society All rights reserved 1362-4393/11 $32.00 www.nture.com/sc ORIGINAL ARTICLE Evlution of tsk-oriented client-centered upper extremity skilled performnce trining

More information

Effect of Preoperative Intravenous Methocarbamol and Intravenous Acetaminophen on Opioid Use After Primary Total Hip and Knee Replacement

Effect of Preoperative Intravenous Methocarbamol and Intravenous Acetaminophen on Opioid Use After Primary Total Hip and Knee Replacement Feture Article Effect of Preopertive Intrvenous Methocrbmol nd Intrvenous Acetminophen on Opioid Use After Primry Totl Hip nd Knee Replcement THOMAS D. LOOKE, MD, PHD; CAMERON T. KLUTH, MBA bstrct Between

More information

CheckMate 153: Randomized Results of Continuous vs 1-Year Fixed-Duration Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer

CheckMate 153: Randomized Results of Continuous vs 1-Year Fixed-Duration Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer CheckMte 53: Rndomized Results of Continuous vs -Yer Fixed-Durtion Nivolumb in Ptients With Advnced Non-Smll Cell Lung Cncer Abstrct 297O Spigel DR, McCleod M, Hussein MA, Wterhouse DM, Einhorn L, Horn

More information

Efficacy of Pembrolizumab in Patients With Advanced Melanoma With Stable Brain Metastases at Baseline: A Pooled Retrospective Analysis

Efficacy of Pembrolizumab in Patients With Advanced Melanoma With Stable Brain Metastases at Baseline: A Pooled Retrospective Analysis Efficcy of Pembrolizumb in Ptients With Advnced Melnom With Stble Brin Metstses t Bseline: A Pooled Retrospective Anlysis Abstrct 1248PD Hmid O, Ribs A, Dud A, Butler MO, Crlino MS, Hwu WJ, Long GV, Ancell

More information

The Acute Time Course of Concurrent Activation Potentiation

The Acute Time Course of Concurrent Activation Potentiation Mrquette University e-publictions@mrquette Exercise Science Fculty Reserch nd Publictions Exercise Science, Deprtment of 1-1-2010 The Acute Time Course of Concurrent Activtion Potentition Luke Grceu Mrquette

More information

Y. Yazici 1, D. Moniz Reed 2, C. Klem 2, L. Rosenblatt 2, G. Wu 2, J.M. Kremer 3

Y. Yazici 1, D. Moniz Reed 2, C. Klem 2, L. Rosenblatt 2, G. Wu 2, J.M. Kremer 3 Greter remission rtes in ptients with erly versus long-stnding disese in biologic-nive rheumtoid rthritis ptients treted with btcept: post hoc nlysis of rndomised clinicl tril dt Y. Yzici 1, D. Moniz Reed

More information

Original Article. T Akter 1, N Islam 2, MA Hoque 3, S Khanam 4, HA khan 5, BK Saha 6. Abstract:

Original Article. T Akter 1, N Islam 2, MA Hoque 3, S Khanam 4, HA khan 5, BK Saha 6. Abstract: Fridpur Med. Coll. J. 214;9(2):61-67 Originl Article Nebuliztion by Isotonic Mgnesium Sulphte Solution with Provide Erly nd Better Response s Compred to Conventionl Approch ( Plus Norml Sline) in Acute

More information

Ultrasound in Treatment of Painful Shoulders in Patients with Hemiplegia

Ultrasound in Treatment of Painful Shoulders in Patients with Hemiplegia Ultrsound in Tretment of Pinful Shoulders in Ptients with Hemiplegi MARGARET K. INABA, M.P.A., nd MARIJEAN PIORKOWSKI, B.S. A study of thirty-three ptients ws conducted to test the hypothesis tht ultrsound

More information

Pilot Trial of Osteopathic Manipulative Therapy for Patients With Frequent Episodic Tension-Type Headache

Pilot Trial of Osteopathic Manipulative Therapy for Patients With Frequent Episodic Tension-Type Headache Pilot Tril of Osteopthic Mnipultive Therpy for Ptients With Frequent Episodic Tension-Type Hedche Guido Rolle, MD, DO (Itly); Lucio Tremolizzo, MD, PhD; Frncesco Somlvico, MS; Crlo Ferrrese, MD, PhD; nd

More information

Hypertension, hyperinsulinaemia and obesity in middle-aged Finns with impaired glucose tolerance

Hypertension, hyperinsulinaemia and obesity in middle-aged Finns with impaired glucose tolerance Journl of Humn Hypertension (1998) 12, 265 269 1998 Stockton Press. All rights reserved 0950-9240/98 $12.00 ORIGINAL ARTICLE Hypertension, hyperinsulinemi nd obesity in middle-ged Finns with impired glucose

More information

Metabolic Syndrome and Health-related Quality of Life in Obese Individuals Seeking Weight Reduction

Metabolic Syndrome and Health-related Quality of Life in Obese Individuals Seeking Weight Reduction Metbolic Syndrome nd Helth-relted Qulity of Life in Obese Individuls Seeking Weight Reduction Adm Gilden Tsi 1, Thoms A. Wdden 1, Dvid B. Srwer 1, Robert I. Berkowitz 1, Leslie G. Womble 1, Louise A. Hesson

More information

Safety and Tolerability of Subcutaneous Sarilumab and Intravenous Tocilizumab in Patients With RA

Safety and Tolerability of Subcutaneous Sarilumab and Intravenous Tocilizumab in Patients With RA Sfety nd Tolerbility of Subcutneous Srilumb nd Intrvenous Tocilizumb in Ptients With RA Pul Emery, 1 Jun Rondon, 2 Anju Grg, 3 Hubert vn Hoogstrten, 3 Neil M.H. Grhm, 4 Ming Liu, 4 Nncy Liu, 3 Jnie Prrino,

More information

Fat intake in patients newly diagnosed with type 2 diabetes: a 4-year follow-up study in general practice

Fat intake in patients newly diagnosed with type 2 diabetes: a 4-year follow-up study in general practice Originl ppers Ft intke in ptients newly dignosed with type 2 dibetes: 4-yer follow-up study in generl prctice Floris A vn de Lr, Eloy H vn de Lisdonk, Peter L B J Lucssen, J M H Tigchelr, Sski Meyboom,

More information

Health-Related Quality of Life and Symptoms of Depression in Extremely Obese Persons Seeking Bariatric Surgery

Health-Related Quality of Life and Symptoms of Depression in Extremely Obese Persons Seeking Bariatric Surgery Oesity Surgery, 15, 3-39 Helth-Relted Qulity of Life nd Symptoms of Depression in Extremely Oese Persons Seeking Britric Surgery Anthony N. Frictore, PhD; Thoms A. Wdden, PhD; Dvid B. Srwer, PhD; Myles

More information

Health Coaching: A Preliminary Report on the Effects in Traumatic Brain Injury/Polytrauma Patients

Health Coaching: A Preliminary Report on the Effects in Traumatic Brain Injury/Polytrauma Patients ORIGINAL RESEARCH Helth Coching: A Preliminry Report on the Effects in Trumtic Brin Injury/Polytrum Ptients Esmerld Mdrigl, MSW; Mx Gry, BA; Molly A. Timmermn, DO; Ttin Orozco, PhD; Dine Cowper Ripley,

More information

EFFECTS OF AN ACUTE ENTERIC DISEASE CHALLENGE ON IGF-1 AND IGFBP-3 GENE EXPRESSION IN PORCINE SKELETAL MUSCLE

EFFECTS OF AN ACUTE ENTERIC DISEASE CHALLENGE ON IGF-1 AND IGFBP-3 GENE EXPRESSION IN PORCINE SKELETAL MUSCLE Swine Dy 22 Contents EFFECTS OF AN ACUTE ENTERIC DISEASE CHALLENGE ON IGF-1 AND IGFBP-3 GENE EXPRESSION IN PORCINE SKELETAL MUSCLE B. J. Johnson, J. P. Kyser, J. D. Dunn, A. T. Wyln, S. S. Dritz 1, J.

More information

THE natural course of sciatica 22,17,23 is favourable in most

THE natural course of sciatica 22,17,23 is favourable in most Predicting the outcome of scitic t short-term follow-up Ptrick C A J Vroomen, M C T F M de Krom nd J A Knottnerus Originl ppers SUMMARY Bckground: The prognostic vlue of the clinicl findings elicited in

More information

Comparison of three simple methods for the

Comparison of three simple methods for the J. clin. Pth. (1967), 2, 5 Comprison of three simple methods for the ssessment of 'free' thyroid hormone T. M. D. GIMLETTE1 From the Rdio-Isotope Lbortory, St. Thoms's Hospitl, London SYNOPSIS A dilysis

More information

Effect of vitamin D on the recurrence rate of rheumatoid arthritis

Effect of vitamin D on the recurrence rate of rheumatoid arthritis 1812 Effect of vitmin D on the recurrence rte of rheumtoid rthritis JUNXIA YANG 1, LIN LIU 1, QINGLIN ZHANG 2, MEIRONG LI 1 nd JINGYA WANG 1 1 Deprtment of Rheumtology, 2 Centrl Lbortory, Xuzhou Centrl

More information

Opioid Use and Survival at the End of Life: A Survey of a Hospice Population

Opioid Use and Survival at the End of Life: A Survey of a Hospice Population 532 Journl of Pin nd Symptom Mngement Vol. 32 No. 6 December 2006 NHPCO Originl Article Opioid Use nd Survivl t the End of Life: A Survey of Hospice Popultion Russell K. Portenoy, MD, Un Sibircev, BA,

More information

Chilblains (pernio, perniosis) are cold-induced, painful or itching

Chilblains (pernio, perniosis) are cold-induced, painful or itching Nifedipine vs Plcebo for Tretment of Chronic Chilblins: A Rndomized Controlled Tril Ibo H. Souwer, MD 1 Jcobus H. J. Bor, BSc (Mth) 2 Pul Smits, MD, PhD 3 Antoine L. M. Lgro-Jnssen, MD, PhD 1 1 Deprtment

More information

Addendum to the Evidence Review Group Report on Aripiprazole for the treatment of schizophrenia in adolescents (aged years)

Addendum to the Evidence Review Group Report on Aripiprazole for the treatment of schizophrenia in adolescents (aged years) Addendum to the Evidence Review Group Report on Aripiprzole for the tretment of schizophreni in dolescents (ged 15-17 yers) Produced by Authors Correspondence to Southmpton Helth Technology Assessments

More information

Recall Bias in Childhood Atopic Diseases Among Adults in The Odense Adolescence Cohort Study

Recall Bias in Childhood Atopic Diseases Among Adults in The Odense Adolescence Cohort Study Syddnsk Universitet Recll Bis in Childhood Atopic Diseses Among Adults in The Odense Adolescence Cohort Study Mørtz, Chrlotte G; Andersen, Klus Ejner; Bindslev-Jensen, Crsten Published in: Act Dermto-Venereologic

More information

PNEUMOVAX 23 is recommended by the CDC for all your appropriate adult patients at increased risk for pneumococcal disease 1,2 :

PNEUMOVAX 23 is recommended by the CDC for all your appropriate adult patients at increased risk for pneumococcal disease 1,2 : PNEUMOVAX 23 is recommended y the CDC for ll your pproprite dult ptients t incresed risk for pneumococcl disese 1,2 : Adults ged

More information

A review of the patterns of docetaxel use for hormone-resistant prostate cancer at the Princess Margaret Hospital

A review of the patterns of docetaxel use for hormone-resistant prostate cancer at the Princess Margaret Hospital MEDICAL ONCOLOGY A review of the ptterns of docetxel use for hormone-resistnt prostte cncer t the Princess Mrgret Hospitl S.N. Chin MD,* L. Wng MSc, M. Moore MD,* nd S.S. Sridhr MD MSc* ABSTRACT Bckground

More information

The Effects of Small Sized Rice Bowl on Carbohydrate Intake and Dietary Patterns in Women with Type 2 Diabetes

The Effects of Small Sized Rice Bowl on Carbohydrate Intake and Dietary Patterns in Women with Type 2 Diabetes Originl Article doi: 10.4093/kdj.2010.34.3.166 pissn 1976-9180 eissn 2093-2650 The Effects of Smll Sized Rice Bowl on Crbohydrte Intke nd Dietry Ptterns in Women with Type 2 Dibetes Hee-Jung Ahn 1, *,

More information

Community. Profile Big Horn County. Public Health and Safety Division

Community. Profile Big Horn County. Public Health and Safety Division Community Helth Profile 2015 Big Horn County Public Helth nd Sfety Division Tble of Contents Demogrphic Informtion 1 Communicble Disese 3 Chronic Disese 4 Mternl nd Child Helth 10 Mortlity 12 Behviorl

More information

Work-related musculoskeletal disorders (WMSDs) among nursing personnel

Work-related musculoskeletal disorders (WMSDs) among nursing personnel Work-Relted Musculoskeletl Injuries nd Disorders Among Occuptionl nd Physicl Therpists Amy R. Drrgh, Wendy Huddleston, Phyllis King KEY WORDS ccidents, occuptionl moving nd lifting ptients musculoskeletl

More information

Short-term health-related quality of life consequences in a lung cancer CT screening trial (NELSON)

Short-term health-related quality of life consequences in a lung cancer CT screening trial (NELSON) British Journl of Cncer (2010) 102, 27 34 & 2010 Cncer Reserch UK All rights reserved 0007 0920/10 $32.00 www.bjcncer.com Short-term helth-relted qulity of life consequences in lung cncer CT screening

More information

Body mass index, waist-to-hip ratio, and metabolic syndrome as predictors of middle-aged men's health

Body mass index, waist-to-hip ratio, and metabolic syndrome as predictors of middle-aged men's health Originl Article - Sexul Dysfunction/Infertility pissn 2005-6737 eissn 2005-6745 Body mss index, wist-to-hip rtio, nd metbolic syndrome s predictors of middle-ged men's helth Jung Hyun Prk *, In-Chng Cho

More information

Community. Profile Powell County. Public Health and Safety Division

Community. Profile Powell County. Public Health and Safety Division Community Helth Profile 2015 Powell County Public Helth nd Sfety Division Tble of Contents Demogrphic Informtion 1 Communicble Disese 3 Chronic Disese 4 Mternl nd Child Helth 10 Mortlity 12 Behviorl Risk

More information

Community. Profile Yellowstone County. Public Health and Safety Division

Community. Profile Yellowstone County. Public Health and Safety Division Community Helth Profile 2015 Yellowstone County Public Helth nd Sfety Division Tble of Contents Demogrphic Informtion 1 Communicble Disese 3 Chronic Disese 4 Mternl nd Child Helth 10 Mortlity 12 Behviorl

More information

Community. Profile Lewis & Clark County. Public Health and Safety Division

Community. Profile Lewis & Clark County. Public Health and Safety Division Community Helth Profile 2015 Lewis & Clrk County Public Helth nd Sfety Division Tble of Contents Demogrphic Informtion 1 Communicble Disese 3 Chronic Disese 4 Mternl nd Child Helth 10 Mortlity 12 Behviorl

More information

Community. Profile Missoula County. Public Health and Safety Division

Community. Profile Missoula County. Public Health and Safety Division Community Helth Profile 2015 Missoul County Public Helth nd Sfety Division Tble of Contents Demogrphic Informtion 1 Communicble Disese 3 Chronic Disese 4 Mternl nd Child Helth 10 Mortlity 12 Behviorl Risk

More information

Community. Profile Anaconda- Deer Lodge County. Public Health and Safety Division

Community. Profile Anaconda- Deer Lodge County. Public Health and Safety Division Community Helth Profile 2015 Ancond- Deer Lodge County Public Helth nd Sfety Division Tble of Contents Demogrphic Informtion 1 Communicble Disese 3 Chronic Disese 4 Mternl nd Child Helth 10 Mortlity 12

More information

Esthetic Influence of Negative Space in the Buccal Corridor during Smiling

Esthetic Influence of Negative Space in the Buccal Corridor during Smiling Originl Article Esthetic Influence of Negtive Spce in the Buccl Corridor during Smiling Dltro Enes Ritter ; Luiz Gonzg Gndini Jr b ; Ary dos Sntos Pinto c ; Arno Locks d ABSTRACT The purpose of this study

More information

A cross-sectional and follow-up study of leukopenia in tuberculosis patients: prevalence, risk factors and impact of anti-tuberculosis

A cross-sectional and follow-up study of leukopenia in tuberculosis patients: prevalence, risk factors and impact of anti-tuberculosis Originl Article A cross-sectionl nd follow-up study of leukopeni in tuberculosis ptients: prevlence, risk fctors nd impct of nti-tuberculosis tretment Fei-Shen Lin 1 *, Mei-Ying Wu 2 *, Wen-Jun Tu 3, Hong-Qiu

More information

Preliminary Findings of a Randomized Controlled Trial of an Interdisciplinary Military Pain Program

Preliminary Findings of a Randomized Controlled Trial of an Interdisciplinary Military Pain Program MILITARY MEDICINE, 174, 3:270, 2009 Preliminry Findings of Rndomized Controlled Tril of n Interdisciplinry Militry Pin Progrm Robert J. Gtchel, PhD * ; Donld D. McGery, PhD ; Aln Peterson, PhD ; Mysti

More information

Arthroscopic Anatomy of Shoulder

Arthroscopic Anatomy of Shoulder Arthroscopic Antomy of Shoulder Murt Bozkurt, Mehmet Emin Simsek, nd Hlil İrhim Açr 2 2.1 Introduction In the lst 30 yers, shoulder rthroscopy hs ecome of greter importnce in the dignosis nd tretment of

More information

Emerging Options for Thromboprophylaxis After Orthopedic Surgery: A Review of Clinical Data

Emerging Options for Thromboprophylaxis After Orthopedic Surgery: A Review of Clinical Data Emerging Options for Thromboprophylxis After Orthopedic Surgery: A Review of Clinicl Dt Bob L. Lobo, Phrm.D. In four rndomized, controlled studies of ptients undergoing orthopedic surgery, the ntithrombotic

More information

LATE RESULTS OF TRANSFER OF THE TIBIAL TUBERCLE FOR RECURRENT DISLOCATION OF THE PATELLA1

LATE RESULTS OF TRANSFER OF THE TIBIAL TUBERCLE FOR RECURRENT DISLOCATION OF THE PATELLA1 LATE RESULTS OF TRANSFER OF THE TIBIAL TUBERCLE FOR RECURRENT DISLOCATION OF THE PATELLA1 W. G. J. HAMPSON nd P. HILL, BRISTOL, ENGLAND The uthors wished to determine the lte results of the Huser opertion,

More information

C reactive protein: an aid to assessment and

C reactive protein: an aid to assessment and C rective protein: n id to ssessment nd monitoring of cute pncretitis J Clin Pthol 1984;37:27-211 AD MAYR,* MJ McMAHON,* MARGART BOWN,t H COOPRt From the *University Deprtment ofsurgery, Generl Infrmry,

More information

Introduction. These patients benefit less from conventional chemotherapy than patients identified as MMR proficient or microsatellite stable 3-5

Introduction. These patients benefit less from conventional chemotherapy than patients identified as MMR proficient or microsatellite stable 3-5 Nivolumb + Ipilimumb Combintion in Ptients With DNA Mismtch Repir-Deficient/Microstellite Instbility-High Metsttic Colorectl Cncer: First Report of the Full Cohort From CheckMte-142 Abstrct 553 André T,

More information

Summary of Package Insert 1

Summary of Package Insert 1 Summry of Pckge Insert 1 For Sttes with Non-Published Policies Indictions Non-infected prtil nd full-thickness skin ulcers due to VSU 2 of greter thn 1 month durtion nd which hve not dequtely responded

More information

ABC Fax Original Paper

ABC Fax Original Paper Originl Pper Nephron 1999;83:31 39 Accepted: My 4, 1999 Qulity of Life in End-Stge Renl Disese Ptients fter Successful Kidney Trnsplnttion: Development of the ESRD Symptom Checklist Trnsplnttion Module

More information

Supplementary Online Content

Supplementary Online Content Supplementry Online Content Rieckmnn N, Kronish IM, Shpiro PA, Whng W, Dvidson KW. Serotonin reuptke inhibitor use, depression, nd long-term outcomes fter n cute coronry : prospective cohort study. JAMA

More information

Analysis of alternatives for insulinizing patients to achieve glycemic control and avoid accompanying risks of hypoglycemia

Analysis of alternatives for insulinizing patients to achieve glycemic control and avoid accompanying risks of hypoglycemia 284 Anlysis of lterntives for izing ptients to chieve glycemic control nd void ccompnying risks of hypoglycemi JIALIN GAO 1,2*, QIANYIN XIONG 1,2*, JUN MIAO 1*, YAO ZHANG 2,3, LIBING XIA 1, MEIQIN LU 1,

More information

Impact of Pharmacist Intervention on Diabetes Patients in an Ambulatory Setting

Impact of Pharmacist Intervention on Diabetes Patients in an Ambulatory Setting Impct of Phrmcist Intervention on Dibetes Ptients in n Ambultory Setting Julie Stding, PhrmD, CDE, Jmie Herrmnn, PhrmD, Ryn Wlters, MS, Chris Destche, PhrmD, nd Aln Chock, PhrmD Dibetes is the seventh-leding

More information

Using Paclobutrazol to Suppress Inflorescence Height of Potted Phalaenopsis Orchids

Using Paclobutrazol to Suppress Inflorescence Height of Potted Phalaenopsis Orchids Using Pcloutrzol to Suppress Inflorescence Height of Potted Phlenopsis Orchids A REPORT SUBMITTED TO FINE AMERICAS Linsey Newton nd Erik Runkle Deprtment of Horticulture Spring 28 Using Pcloutrzol to Suppress

More information

Invasive Pneumococcal Disease Quarterly Report. July September 2017

Invasive Pneumococcal Disease Quarterly Report. July September 2017 Invsive Pneumococcl Disese Qurterly Report July September 2017 Prepred s prt of Ministry of Helth contrct for scientific services by Rebekh Roos Helen Heffernn October 2017 Acknowledgements This report

More information

Inhaled Corticosteroid Is Associated With an Increased Risk of TB in Patients With COPD

Inhaled Corticosteroid Is Associated With an Increased Risk of TB in Patients With COPD CHEST Originl Reserch Inhled Corticosteroid Is Associted With n Incresed Risk of TB in Ptients With COPD Jung-Hyun Kim, MD ; Ji-Soo Prk, MD ; Kyung-Ho Kim, MD ; Hye-Cheol Jeong, MD ; Eun-Kyung Kim, MD

More information

Effect on Glycemic, Blood Pressure, and Lipid Control according to Education Types

Effect on Glycemic, Blood Pressure, and Lipid Control according to Education Types Originl Article http://dx.doi.org/10.4093/dmj.2011.35.6.580 pissn 2233-6079 eissn 2233-6087 D I A B E T E S & M E T A B O L I S M J O U R N A L Effect on Glycemic, Blood Pressure, nd Lipid Control ccording

More information

IJPHY EFFECTS OF WEARING HEADSCARVES ON CERVICAL SPINE MOBILITY ABSTRACT. Int J Physiother. Vol 5(3), , June (2018) ISSN:

IJPHY EFFECTS OF WEARING HEADSCARVES ON CERVICAL SPINE MOBILITY ABSTRACT. Int J Physiother. Vol 5(3), , June (2018) ISSN: Int J Physiother. Vol 5(3), 113-118, June (2018) ISSN: 2348-8336 ORIGINAL ARTICLE IJPHY ABSTRACT EFFECTS OF WEARING HEADSCARVES ON CERVICAL SPINE MOBILITY *1 Smih F. Alqbbni, DSc ²Gurinder S. Bins, PhD

More information

Debra A. Ignaut, R.N., B.S., C.D.E., and Haoda Fu, Ph.D.

Debra A. Ignaut, R.N., B.S., C.D.E., and Haoda Fu, Ph.D. Journl of Dietes Science nd Technology Volume 6, Issue 2, Mrch 2012 Dietes Technology Society TECHNOLOGY REPORT Comprison of Insulin Diluent Lekge Postinjection Using Two Different Needle Lengths nd Injection

More information

Analysis of Risk Factors for the Development of Incisional and Parastomal Hernias in Patients after Colorectal Surgery

Analysis of Risk Factors for the Development of Incisional and Parastomal Hernias in Patients after Colorectal Surgery Originl Article Journl of the Koren Society of J Koren Soc Coloproctol 2012;28(6):299-303 http://dx.doi.org/10.3393/jksc.2012.28.6.299 pissn 2093-7822 eissn 2093-7830 Anlysis of Risk Fctors for the Development

More information

Community. Profile Carter County. Public Health and Safety Division

Community. Profile Carter County. Public Health and Safety Division Community Helth Profile 2015 Crter County Public Helth nd Sfety Division Tble of Contents Demogrphic Informtion 1 Communicble Disese 3 Chronic Disese 4 Mternl nd Child Helth 10 Mortlity 12 Behviorl Risk

More information

Abstract. Background. Aim. Patients and Methods. Patients. Study Design

Abstract. Background. Aim. Patients and Methods. Patients. Study Design Impct of the Use of Drugs nd Substitution Tretments on the Antivirl Tretment of Chronic Heptitis C: Anlysis of Complince, Virologicl Response nd Qulity of Life (CHEOBS). Melin, 1 J.-. Lng, D. Ouzn, 3 M.

More information

Teacher motivational strategies and student self-determination in physical education

Teacher motivational strategies and student self-determination in physical education Loughborough University Institutionl Repository Techer motivtionl strtegies nd student self-determintion in physicl eduction This item ws submitted to Loughborough University's Institutionl Repository

More information

27 June Bmnly L. WALTER ET AL.: RESPONSE OF CERVICAL CANCERS TO IRRADIATION

27 June Bmnly L. WALTER ET AL.: RESPONSE OF CERVICAL CANCERS TO IRRADIATION 27 June 1964 Bmnly MEDICAL JOURNAL L. WALTER ET AL.: RESPONSE OF CERVICAL CANCERS TO IRRADIATION x 1,638.) FIG. 2.-Foci of sme tumour s in Fig. 1 contining vible tumour cells with scnty cytoplsm, reltively

More information

WSU Tree Fruit Research and Extension Center, Wenatchee (509) ext. 265;

WSU Tree Fruit Research and Extension Center, Wenatchee (509) ext. 265; FINAL REPORT WTFRC Project # AH-1-5 WSU Project # 13C-355-3 Project title: PI: Orgniztion: Coopertors: of Sunburn in Apples with RAYNOX Lrry Schrder, Horticulturist WSU Tree Fruit Reserch nd Extension

More information

Original Article INTRODUCTION. Korean Diabetes J 2010;34: doi: /kdj pissn eissn

Original Article INTRODUCTION. Korean Diabetes J 2010;34: doi: /kdj pissn eissn Originl Article doi: 1.493/kdj.21.34.6.34 pissn 1976-918 eissn 293-265 The Smll Rice Bowl-Bsed Mel Pln ws Effective t Reducing Dietry Energy Intke, Body Weight, nd Blood Glucose Levels in Koren Women with

More information

Characteristics of hip involvement in patients with ankylosing spondylitis in Korea

Characteristics of hip involvement in patients with ankylosing spondylitis in Korea ORIGINAL ARTICLE Koren J Intern Med 2017;32:158-164 Chrcteristics of hip involvement in ptients with nkylosing spondylitis in Kore Hyemin Jeong, Yeong Hee Eun, In Young Kim, Hyungjin Kim, Jejoon Lee, Eun-Mi

More information

Journal of Cystic Fibrosis 1 (2002)

Journal of Cystic Fibrosis 1 (2002) Journl of Cystic Fibrosis 1 (2002) 276 280 Assessment of nutritionl sttus in children with cystic fibrosis: conventionl nthropometry nd bioelectricl impednce nlysis. A cross-sectionl study in Dutch ptients,

More information

Effects of 6-Month Sitagliptin Treatment on Insulin and Glucagon Responses in Korean Patients with Type 2 Diabetes Mellitus

Effects of 6-Month Sitagliptin Treatment on Insulin and Glucagon Responses in Korean Patients with Type 2 Diabetes Mellitus Originl Article Others Dibetes Metb J 215;39:335-341 http://dx.doi.org/1.493/dmj.215.39.4.335 pissn 2233-679 eissn 2233-687 DIABETES & METABOLISM JOURNAL Effects of 6-Month Sitgliptin Tretment on Insulin

More information

Clinical statistics analysis on the characteristics of pneumoconiosis of Chinese miner population

Clinical statistics analysis on the characteristics of pneumoconiosis of Chinese miner population Originl Article Clinicl sttistics nlysis on the chrcteristics of pneumoconiosis of Chinese miner popultion Mei-Fng Wng 1 *, Run-Ze Li 2 *, Ying Li 2, Xue-Qin Cheng 1, Jun Yng 1, Wen Chen 3, Xing-Xing Fn

More information

ORIGINAL ARTICLE. Validity and Reliability of the Revised Convergence Insufficiency Symptom Survey in Children Aged 9 to 18 Years

ORIGINAL ARTICLE. Validity and Reliability of the Revised Convergence Insufficiency Symptom Survey in Children Aged 9 to 18 Years 1040-5488/03/8012-0832/0 VOL. 80, NO. 12, PP. 832 838 OPTOMETRY AND VISION SCIENCE Copyright 2003 Americn Acdemy of Optometry ORIGINAL ARTICLE Vlidity nd Relibility of the Revised Convergence Insufficiency

More information

Summary. Effect evaluation of the Rehabilitation of Drug-Addicted Offenders Act (SOV)

Summary. Effect evaluation of the Rehabilitation of Drug-Addicted Offenders Act (SOV) Summry Effect evlution of the Rehbilittion of Drug-Addicted Offenders Act (SOV) The Rehbilittion of Drug-Addicted Offenders Act (SOV) ws lunched on April first 2001. This lw permitted the compulsory plcement

More information

Efficacy of biofeedback training in improving faecal

Efficacy of biofeedback training in improving faecal Gut, 199, 31, 1395-142 Deprtment of Peditrics, niversity of Iow, Iow City, Iow, SA V Loening-Bucke Correspondence to: Dr V Loening-Bucke, Deprtment of Peditrics, niversity of Iow Hospitls nd Clinics, Iow

More information

Rheumatoid-susceptible alleles of HLA-DRB 1 are genetically recessive to non-susceptible alleles in the progression of bone destruction in the wrists

Rheumatoid-susceptible alleles of HLA-DRB 1 are genetically recessive to non-susceptible alleles in the progression of bone destruction in the wrists Annls of the Rheumtic Diseses 1994; 53: 587-592 587 Deprtment of Orthopedic Surgery, Knsi Medicl University, Otokoym Hospitl, Kyoto, Jpn Y Tod Y Mori Deprtment of Orthopedic Surgery, Knsi Medicl University,

More information

SYNOPSIS Final Abbreviated Clinical Study Report for Study CA ABBREVIATED REPORT

SYNOPSIS Final Abbreviated Clinical Study Report for Study CA ABBREVIATED REPORT Finl Arevited Clinicl Study Report Nme of Sponsor/Compny: Bristol-Myers Squi Ipilimum Individul Study Tle Referring to the Dossier (For Ntionl Authority Use Only) Nme of Finished Product: Yervoy Nme of

More information

Review article. Key words non specific low back pain, exercise therapy, stretching, motor control. Grade D

Review article. Key words non specific low back pain, exercise therapy, stretching, motor control. Grade D Spinl Surgery 31 2 140 144 2017 総説 Review rticle Astrct Exercise therpy is useful for low ck pin. Exercise therpy ims to improve posturl lignment, muscle strength, nd endurnce, nd lso contriutes to pin

More information

Flexion Contracture Following Primary Total Knee Arthroplasty: Risk Factors and Outcomes

Flexion Contracture Following Primary Total Knee Arthroplasty: Risk Factors and Outcomes Feture Article Flexion Contrcture Following Primry Totl Knee Arthroplsty: Risk Fctors nd Outcomes STUART T. GOUDIE, MBCHB; ANGELA H. DEAKIN, PHD; AFTAB AHMAD, FRCS; ROHIT MAHESHWARI, MS, FRCS; FREDERIC

More information

Changes in Occlusal Relationships in Mixed Dentition Patients Treated with Rapid Maxillary Expansion

Changes in Occlusal Relationships in Mixed Dentition Patients Treated with Rapid Maxillary Expansion Originl Article Chnges in Occlusl Reltionships in Mixed Dentition Ptients Treted with Rpid Mxillry Expnsion A Prospective Clinicl Study Jmes A. McNmr,Jr ; Luren M. Sigler b ; Lorenzo Frnchi c ; Susn S.

More information

EVALUATION OF DIFFERENT COPPER SOURCES AS A GROWTH PROMOTER IN SWINE FINISHING DIETS 1

EVALUATION OF DIFFERENT COPPER SOURCES AS A GROWTH PROMOTER IN SWINE FINISHING DIETS 1 Swine Dy 2001 Contents EVALUATION OF DIFFERENT COPPER SOURCES AS A GROWTH PROMOTER IN SWINE FINISHING DIETS 1 C. W. Hstd, S. S. Dritz 2, J. L. Nelssen, M. D. Tokch, nd R. D. Goodbnd Summry Two trils were

More information

Analysis of detection results of thyroid function-related indexes in pregnant women and establishment of the reference interval

Analysis of detection results of thyroid function-related indexes in pregnant women and establishment of the reference interval EXPERIMENTAL AND THERAPEUTIC MEDICINE Anlysis of detection results of thyroid function-relted indexes in pregnnt women nd estblishment of the reference intervl QI ZHOU 1*, YANLI ZHANG 1*, JIANHUA ZHOU

More information

Results. Table 1: Demographic and Baseline Characteristics, Open-Label Safety Population Prior Double-Blind OC/APAP ER (n=77)

Results. Table 1: Demographic and Baseline Characteristics, Open-Label Safety Population Prior Double-Blind OC/APAP ER (n=77) Open-Lbel Extension of Rndomized, Double-Blind, Plcebo-Controlled, Phse 3 Study of the Sfety nd Anlgesic Efficcy of MNK-795 Oxycodone/Acetminophen Extended-Relese (OC/APAP ER) Tblets in n Acute Pin Model

More information

phosphatase isoenzyme activity: estimation of

phosphatase isoenzyme activity: estimation of J Clin Pthol 1988;41:202-206 Quntittive method for determining serum lkline phosphtse isoenzyme ctivity: estimtion of intestinl component M J PEAKE, M PEJAKOVIC, G H WHITE From the Deprtment ofbiochemistry

More information

Journal of Hainan Medical University 2017; 23(2): Journal of Hainan Medical University.

Journal of Hainan Medical University 2017; 23(2): Journal of Hainan Medical University. Journl of Hinn Medicl University 2017; 23(2): 151-155 151 Journl of Hinn Medicl University http://www.hnykdxxb.com Reltionship between DEXA bone minerl density mesurement results nd serum cytokines s well

More information

C hest physiotherapy is routinely used after major

C hest physiotherapy is routinely used after major Efficcy of Brething nd Coughing Exercises in the Prevention of Pulmonry Complictions After Coronry Artery Surgery* Kthy Stiller, B.App. Sc.; Joseph Montrello, M.B.B. S.; Mlcolm Wllce, M. B. B. S. ; Meredith

More information

Hallux valgus and cartilage degeneration in the first metatarsophalangeal joint

Hallux valgus and cartilage degeneration in the first metatarsophalangeal joint Hllux vlgus nd crtilge degenertion in the first mettrsophlngel joint P. Bock, K.-H. Kristen, A. Kröner, A. Engel From the Dnue Hospitl, Vienn, Austri This study reltes the extent of crtilge lesions within

More information

Different type 2 diabetes risk assessments predict dissimilar numbers at high risk :

Different type 2 diabetes risk assessments predict dissimilar numbers at high risk : Reserch Benjmin J Gry, Richrd M Brcken, Dniel Turner, Kerry Morgn, Michel Thoms, Slly P Willims, Meurig Willims, Sm Rice nd Jeffrey W Stephens on behlf of the Prosiect Sir Gâr Group Different type 2 dibetes

More information

Effects of neurodevelopmental treatment (NDT) for cerebral palsy: an AACPDM evidence report. Annotation

Effects of neurodevelopmental treatment (NDT) for cerebral palsy: an AACPDM evidence report. Annotation Effects of neurodevelopmentl tretment (NDT) for cerebrl plsy: n AACPDM evidence report Annottion Written by Chrlene Butler* EdD Johnn Drrh PhD Approved by AACPDM Tretment Outcomes Committee Review Pnel:

More information

Balance, Body Motion, and Muscle Activity After High-Volume Short-Term Dance-Based Rehabilitation in Persons With Parkinson Disease: A Pilot Study

Balance, Body Motion, and Muscle Activity After High-Volume Short-Term Dance-Based Rehabilitation in Persons With Parkinson Disease: A Pilot Study RESEARCH ARTICLES Blnce, Body Motion, nd Muscle Activity After High-Volume Short-Term Dnce-Bsed Rehbilittion in Persons With Prkinson Disese: A Pilot Study J. Lucs McKy, PhD, MSCR, Len H. Ting, PhD, nd

More information

Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence

Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence Clinicin Summry Mentl Helth Eting Disorders Mngement nd Outcomes of Binge-Eting Disorder in Adults: Current Stte of the Evidence Focus of This Summry This is summry of systemtic review evluting the evidence

More information

Influence of the Duration of Diabetes on the Outcome of a Diabetes Self-Management Education Program

Influence of the Duration of Diabetes on the Outcome of a Diabetes Self-Management Education Program Originl Article Clinicl Cre/Eduction http://dx.doi.org/10.4093/dmj.2012.36.3.222 pissn 2233-6079 eissn 2233-6087 D I A B E T E S & M E T A B O L I S M J O U R N A L Influence of the Durtion of Dibetes

More information

Handgrip exercise elevates basilic venous hemodynamic parameters in healthy subjects

Handgrip exercise elevates basilic venous hemodynamic parameters in healthy subjects interntionl journl of nursing sciences 1 (2014) 389e393 Avilble online t www.sciencedirect.com ScienceDirect journl homepge: http://www.elsevier.com/journls/interntionljournl-of-nursing-sciences/2352-0132

More information

A Comparison of Serum Magnesium Level in Pregnant Women with and without Gestational Diabetes Mellitus (GDM)

A Comparison of Serum Magnesium Level in Pregnant Women with and without Gestational Diabetes Mellitus (GDM) Brief Report J Bbol Univ Med Sci Vol 18, Issu 12; Dec 2016. P:71-75 A Comprison of Serum Mgnesium Level in Pregnnt Women with nd without Gesttionl Dibetes Mellitus (GDM) Z. Bouzri (MD) 1, F. Elmi(MD) 2,

More information

The potential future of targeted radionuclide therapy: implications for occupational exposure? P. Covens

The potential future of targeted radionuclide therapy: implications for occupational exposure? P. Covens The potentil future of trgeted rdionuclide therpy: implictions for occuptionl exposure? Introduction: Trgeted Rdionuclide Therpy (TRT) Systemic tretment Molecule lbelled with rdionuclide delivers toxic

More information

BENIGN ulceration along the greater curvature of the pars media of the

BENIGN ulceration along the greater curvature of the pars media of the BENIGN ULCERS OF THE GREATER CURVATURE OF THE STOMACH Report of Two Cses CHARLES H. BROWN, M.D. Deprtment of Gstroenterology nd ANTHONY D. INTRIERE, M.D.* BENIGN ulcertion long the greter curvture of the

More information

Multiple sclerosis (MS) affects approximately. Triaging Patients with Multiple Sclerosis in the Emergency Department. Room for Improvement

Multiple sclerosis (MS) affects approximately. Triaging Patients with Multiple Sclerosis in the Emergency Department. Room for Improvement Systemtic Review of Tools for Anxiety in MS MS CARE DELIVERY: CHALLENGES AND INVATIONS Triging Ptients with Multiple Sclerosis in the Emergency Deprtment Room for Improvement Heshm Abboud, MD, PhD; Krin

More information

IMpower133: Primary PFS, OS, and safety in a Ph1/3 study of 1L atezolizumab + carboplatin + etoposide in extensive-stage SCLC

IMpower133: Primary PFS, OS, and safety in a Ph1/3 study of 1L atezolizumab + carboplatin + etoposide in extensive-stage SCLC IMpower133: Primry PFS, OS, nd sfety in Ph1/3 study of 1L tezolizumb + crbopltin + etoposide in extensive-stge SCLC S. V. Liu, 1 A. S. Mnsfield, 2 A. Szczesn, 3 L. Hvel, 4 M. Krzkowski, 5 M. J. Hochmir,

More information

Stability of anterior crossbite correction: A randomized controlled trial with a 2-year follow-up

Stability of anterior crossbite correction: A randomized controlled trial with a 2-year follow-up Originl Article Stbility of nterior crossbite correction: A rndomized controlled tril with 2-yer follow-up Ann-Pulin Wiedel ; Lrs Bondemrk b ABSTRACT Objective: To compre nd evlute the stbility of correction

More information

Vitamin D and Mushrooms: Enrichment With Pulsed UV Light. Michael Kalaras Department of Food Science The Pennsylvania State University

Vitamin D and Mushrooms: Enrichment With Pulsed UV Light. Michael Kalaras Department of Food Science The Pennsylvania State University Vitmin D nd Mushrooms: Enrichment With Pulsed UV Light Michel Klrs Deprtment of Food Science The Pennsylvni Stte University Vitmin D Synthesis Source: http://vitmind.ucr.edu/imges/chem1.gif Vitmin D In

More information

Mandibular vertical asymmetry in adult orthodontic patients with different vertical growth patterns: A cone beam computed tomography study

Mandibular vertical asymmetry in adult orthodontic patients with different vertical growth patterns: A cone beam computed tomography study Originl Article Mndibulr verticl symmetry in dult orthodontic ptients with different verticl growth ptterns: A cone bem computed tomogrphy study Slih Celik ; Mevlut Celikoglu b ; Suleymn K. Buyuk c ; A.

More information

Factors affecting psychological stress in children who cooperate with dental treatment: a pilot study

Factors affecting psychological stress in children who cooperate with dental treatment: a pilot study K. Aoygi-Nk, A. Kod, T. Kwkmi, H. Kribe Deprtment of Peditric Dentistry, School of Life Dentistry, Nippon Dentl University, Tokyo, Jpn e-mil: h-kribe@tky.ndu.c.jp Fctors ffecting psychologicl stress in

More information