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1 Biomedical and Physical Functioning General Health Height Weight Waist Circumfernece % Body Fat Tanita scale BMI Self-rated Health - overall clinical protocol Self-rated Health - rel. to age clinical protocol Self-rated Health - rel. to past clinical protocol Conditions/Events Self-reported MOS SF-36 health survey (Ware & Sherbourne, 1992) Conditions/Events, Med Records/Physical clinical protocol Number/Type Prescribed Medications clinical protocol Parents Longevity clinical protocol Baseline Age and Cause of Death clinical protocol Baseline Sibs age and cause of death clinical protocol Sensory Auditory Acuity Qualitative assessment by interviewer Visual Acuity Sensory Disability Based on Neurological Exam & interviewer Hand Grip Strength Grip dynameter Arm Flexion Based on Neurological Exam Knee Extension Based on Neurological Exam Sensation Based on Neurological Exam Cardiovascular / Pulmonary Heart Disease / Hypertension clinical protocol Heart Attack clinical protocol Blood Pressure clinical protocol Pulse oximeter Heart rate Respiratory Disease (Pulmonary Function) Clinical protocol & Peak Flow Meter Page 1 of 5
2 Blood Samples Cholesterol Neurological / Neuropsychological Gait Based on Neurological exam & quantitative measures from gait mat UPDRS Based on Neurological Exam Cranial Nerves & Motor & Reflexes Based on Neurological Exam Balance Based on Neurological Exam- retropulsion Tapping Test Based on Neurological Exam - UPDRS measure Clock Test Hachinski Score Based on Neurological Exam Cerebrovascular / Dementia Cerebrovascular Disease / Stroke clinical protocol & Neurological Exam Dementia Diagnosis DSM-IV - Case Conference Results Clinical Dementia Rating (CDR) Based on Neurological Exam Mild Cognitive Impairment - amnestic & non-amnestic domain specific impairment + complaints Dementia Related questionnaires Informant based - CERAD, IQ Code, Dementia questionnaire for informants Other Systemic Illness Diabetes clinical protocol Cancer clinical protocol Somatic Fatigue self- report Pain self-report questionnaire + measures based on Neurological Exam (below waist measures only) Health Behaviors Drug Use clinical protocol Alcohol Consumption clinical protocol Tobacco Use clincial protocol Diet Not reported Exercise clinical protocol - activities questionnaire Functional Capacity Activities of Daily Living (ADL) Lawton-Broady Questionnaire Page 2 of 5
3 Instrumental ADL (IADL) Lawton-Broady Questionnaire Activity Level clinical protocol - activities questionnaire Hobbies clinical protocol - activities questionnaire Home Help clinical questionnaire Cognitive Functioning Crystallized Knowledge WRAT3 Baseline WAIS Information WAISIII WAIS Similarities WAISIII Collected until 2007 Fluid Reasoning WAIS Block Design WAISIII Stroop Golden Stroop since 2007 Speed Substitution Coding tasks WAISIII DSS Figure Copy Task RBANS Reaction Time Memory WAIS Digit Span Forward / Backward WAISIII Word List Free Recall Free and Cued Selective Reminding Test Prose Recall WMS-R Logical Memory Test Free and Cued Selective Reminding Mental Status Exams Blessed Attention WAIS Digit Span Backward WAISIII Digit Span Backward Other Working Memory Trails A & B Word Fluency Verbal Fluency (Category) Animals, Vegetables, and Fruits FAS Boston Naming Test Self-rated Cognition Self-rated Cognition CERAD questionnaire Self-rated Memory CERAD questionnaire Page 3 of 5
4 Psychosocial and Demographic Personality NEO Personality Scales IPIP version of the NEO since Interpersonal Functioning Social (incl. family) Networks clinical protocol Social Network History clinical protocol Social Support / Informal Help clinical protocol Loneliness Life Satisfaction / Mental Health Mood / Depression GDS, Patient Health Questionnaire - 9 (PHQ- 9) Quality of Life SF-36 Stress / Life Events Life Events Daily Inventory of Stressful Events since Anxiety/Agitation Beck Anxiety Perceived Stress PANAIS since Demographics Education clinical protocol Baseline Occupation clinical protocol Socio-economic Status clinical protocol Family Income clinical protocol Marital Status clinical protocol Living Arrangement clinical protocol Employment History clinical protocol Genetics (Biorepository) DNA extraction Collected at baseline and yr. 2 for each individual individual ApoE COMT LRRK2 IL-6 Page 4 of 5
5 DBH BDNF AdipoQ CETP Neuropatholgy Braak stage Senile plaques(in region): Counts of temporal parietal hippocampal parahippocampal Fibrillary tangles (in region); Counts of temporal parietal hippocampal parahippocampal Path. DX: Primary Secondary Tertiary Page 5 of 5
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