Deep venous thrombosis after spinal surgery: prevention and treatment

Transcription

1 Chinese Journal of Tissue Engineering Research September 28, 2017 Vol.21, No.27 ( ). [J] (27): DOI: /j.issn ORCID: ( ) Charney :R318 :A : (2017) PubMed Deep venous thrombosis after spinal surgery: prevention and treatment Zhou Yi-biao, Zhang Bin ( Jiangxi Medical College of Nanchang University, Nanchang , Jiangxi Province, China; Department of Spinal Surgery, the First Affiliated Hospital of Nanchang University, Nanchang , Jiangxi Province, China) Abstract BACKGROUND: The incidence of deep venous thrombosis of the lower extremity after spinal surgery remains controversial, and its prevention is still under discussion. OBJECTIVE: To summarize the progress of the prevention of the deep venous thrombosis after spinal surgery. METHODS: The domestic and foreign related literature about the deep vein thrombosis after the spinal surgery, which was filtrated from CNKI and PubMed databases, were searched for the articles concerning the prevention of the deep venous thrombosis after spinal surgery published from January 1993 to January Finally, 41 eligible articles were included, and the prevention methods, risk factors and incidence were summarized. RESULTS AND CONCLUSION: (1) With the technology and medical equipment development, more novel technologies and biomaterials are extensively applied in spinal surgery; meanwhile, complex and difficult surgeries, Zhou Yi-biao, Studying for master s degree, Jiangxi Medical College of Nanchang University, Nanchang , Jiangxi Province, China Corresponding author: Zhang Bin, Associate chief physician, Associate professor, Master s supervisor, Department of Spinal Surgery, the First Affiliated Hospital of Nanchang University, Nanchang , Jiangxi Province, China 4416 P.O. Box 10002, Shenyang

2 . big surgical trauma and prolonged operation time all increase the risk of deep venous thrombosis of the lower extremity; thereafter, the incidence is on a rise. (2) The prevention methods of deep venous thrombosis have been improved, and the grading of prevention becomes more sufficient. (3) During venipuncture and injection, upper extremity should be selected firstly, so as to avoid damage to the lower extremity veins. (4) The following studies should concentrate on understanding the epidemic characteristics of deep venous thrombosis of the lower extremity after spinal surgery, and confirming the best prevention time, as well as effective drugs and physical measurements. Subject headings: Spine; Venous Thrombosis; Tertigry Prevention Cite this article: Zhou YB, Zhang B. Deep venous thrombosis after spinal surgery: prevention and treatment. Zhongguo Zuzhi Gongcheng Yanjiu. 2017;21(27): Introduction (venous thromboembolism VTE) 2009 NASS [1] 1 Data and methods 1.1 PubMed spinal surgery deep venous thrombosis prevention [2] Sansone [3] % 0.06% Yang [4] % 2.2 [5] 1946 Virchow ( 1) 2001 [6] / B [7] 2Results ( 360 ) ISSN CN /R CODEN: ZLKHAH 4417

3 . Yang [4] D D D [8] 210 D1 D 3 7 3D (P < 0.05)D D D [9] Logistic I 0.3 µg/ L ng /L D µg/ L [10] [11] (CTPA) d [10] NASS (B) [1] [10] [12] AES 2009 NASS ASA [1] % [13-14] P.O. Box 10002, Shenyang

4 [1] Vitk [15] [16] NASS Xa Xa [17] [18-19] [20-21] Xa [22] [23-24] K [22] Xa 2000 Xa Handschin [25] [26-27] [28] % 20.83% 2.7 [2] [11] ISSN CN /R CODEN: ZLKHAH 4419

5 . [29] [30] 36 h12 h (5 000 U)1 /d NASS [11] PKP [11] (P < 0.05) [31] [32] (AES) [33] d [34] Eriksson [35] % 19.1%(P < 0.001) 2.17% 2.27% (P > 0.05) Gerlach [36] 2013 [37] () Slavik Janni [38-39] [10] 4420 P.O. Box 10002, Shenyang

6 . Bryson [40] Akeda [41] 3 Conclusion and prospects [1] RCT (PRISMA CNKI References [1] Bono CM, Watters WC 3rd, Heggeness MH, et al. An evi-dence-based clinical guideline for the use of antithrombotictherapies in spine surgery. Spine J. 2009;9(12): [2]. [D] [3] Sansone JM,del Rio AM,Anderson PA The prevalence of and s PE cificrisk factors for venous thromboembolic disease following elective spinesurgeryj Bone Joint Surg Am.2010;92: [4] Yang SD, Ding WY, Yang DL, et al. Prevalence and Risk Factors of Deep Vein Thrombosis in,patients Undergoing Lumbar Interbody Fusion Surgery.Medicine.2015;94(48):e2205. [5] Raj D, Marshall RW. Prophylaxis against thromboembolismin spinal surgery. Arch Orthop Trauma Surg.2008;128(7): [6] Zaw HM,Osborne IC,PE ttit PN,et al. Risk factors for venous thromboembolism in ortho PE dic surgery. Isr Med Assoc J.2002;4(11): [7] [J].,2012,22(8): [8]. D-Wells [D]., [9],,,. I B D- [J]., 2012, 11(1): ISSN CN /R CODEN: ZLKHAH 4421

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