45 year old Triathalon/Marathon runner: 5 feet 8 inches 130 lbs

Transcription

1 JE 45 year old Triathalon/Marathon runner: 5 feet 8 inches 130 lbs Will participate in several events per month Has been vegan since age 17 Has had significant food allergies and has been on a Candida diet Has very erratic menstrual cycles Recently has noticed trouble with irregular heart beat or palpitations Complains of fatigue. Tremendous job stress. GI discomfort and bloating Focus and concentration is not what it used to be Is more irritable at the end of the day Has noticed some numbness and tingling in the extremities and has some muscle cramps.

2 JE 4/27/12 Areas of Concern Inflammation & Lipids lipids out of optimal range with more lessprotective than protective HDL subfractions, higher Cholesterol, Lp (a), and VLDL 3 levels increasing risk of heart disease and/or metabolic syndrome (precursor to diabetes) Sex Hormone Balance Estrogen Dominance with more estrogen in relation to progesterone levels with more non protective than protective estrogens & lower progesterone levels; estrogen stimulates growth of female organ systems & can disrupt function & risk of hormonal based cancers (i.e. breast) Stress & Sleep AM cortisol higher than optimal with elevated levels inflammatory & catabolic (body breaks down quicker than it rebuilds muscle, connective tissue, digestive function, cognition, immunity, thyroid function, sex hormone balance, etc); DHEA S lower than optimal, often a result of chronic stressor/s & negatively impacts brain health and speed of aging (physical/mental) Digestive Health digestive inflammation/leaky gut with multiple food sensitivities, which indicates activated immune response causing more inflammatory responses in body; affects ability to break down, absorb, and utilize nutrients for metabolism & health Nutrient Deficiencies? B12 (common in vegetarians) and/or folate o Vitamin D level toxic Thyroid & Metabolic Hormones TSH higher than optimal with Free T3 (up to 10x as metabolically active as Free T4) lower than optimal oftentimes poor conversion from T4 to T3 related to chronic stressor/s (internal + external) Lab Optimal Functioning Values Your Value Comments LIPIDS and INFLAMMATION HDL >50 106? less protective against heart disease depends on what type you have Cholesterol x risk of heart disease Lp (a) Cholesterol <10 11 Genetic variation of LDL in blood; new marker for early onset atherosclerosis HDL 2 most protective >15 41 Less protective in comparison to less protective HDL s HDL 3 less protective >25 65 More less protective HDL s than protective VLDL 3 small remnant <10 12 Sensitive indicator for heart disease

3 & metabolic syndrome LDL Density Pattern LDL Pattern (A) A Great CRP hs < Great inflammatory marker GLUCOSE BALANCE Insulin Low end exercise can decrease as it reactivates insulin receptors on cells ENERGY & METABOLISM THYROID PROFILE TSH Greater than optimal lower thyroid function (energy & metabolism) Free T Ok Free T Lower than optimal; often poor conversion related to chronic stressor/s TPO <20 10 Ok Ferritin Ok iron storage marker CORTISOL & DHEA Adrenal Health and Hormonal Balance AM cortisol, blood Higher than optimal DHEA S, blood Lower than optimal anti aging hormone critical for immunity, sex hormone production, brain health, lean muscle mass retention, speed of aging SEX HORMONE BALANCE Progesterone Follicular Ovulation Luteal Estradiol Follicular Ovulation Luteal Estrone Follicular Midcycle Luteal Estradiol : Estrone ratio Estradiol + Estrone : Progesterone ratio? 0.3 Lower than range OR low end of range if follicular? 16.5? 49 2 : : 1 More non protective than protective estrogens present : : 1 Estrogen dominance more estrogen in relation to progesterone than optimal CORE HEALTH PROFILE IMMUNE SYSTEM WBC ? underactive immune system, allergies, chronic inflammation, vitamin deficiencies MCV ? B12 deficiency MCH ? B12 and/or folate deficiency Neutrophils 40 74% 41 First line of defense against infection? severe/chronic

4 infection or inflammatory response Eosinophils % 0 7% 14? allergies, inflammation, infection MEB s (mono % + eos % + baso %) >7% inflammation >18% digestive inflammation 25% Digestive inflammation/leaky gut Total Protein > Lower protein intake/ poor absorption & utilization of proteins Albumin > Same as above Globulin Immune compromise,? lower HCL production for adequate protein digestion Vitamin D Higher than optimal; toxic levels can cause calcium deposits in soft tissues (kidneys, arteries, heart, ears, lungs) **Values based on: An ebook Consumer s Guide to Interpreting Laboratory Testing. Integrative Health Resources, 2010 ** below are listed in order of sensitivity (lowest to highest sensitivity) Class 1 Class 2 Class 3 Class 4 Lamb Corn Peanut Chicken Rye Cow milk Tomato Green beans Wheat Onions Blue cheese Egg Chocolate/cocoa Soybean Oat Bakers yeast Cane sugar Brewers yeast Class 5

5 Let s break this down into areas of priority for you so that we can establish some goals that need to be achieved: 1st Priority: We need to get your iron, B12 and ferritin pools increased. We will need to measure your iron level. Low iron levels reduce the conversion of T4 to T3. Insufficient iron levels effects the first two of three steps of thyroid hormone synthesis by reducing the activity of the enzyme thyroid peroxidase, which is dependent on iron. Thyroid peroxidase drives building iodine to tyrosine (amino acid) into the thyroid hormone T4 and T3. Low iron levels, which low ferritin reveals, alters the conversion of T4 to T3, besides binding T3. Low iron levels can increase TSH (thyroid stimulating hormone). The American Society of endocrinology recommends taking action at a TSH of 2.5. It is clear that there is an imbalance here but we need more labs to figure out what step to take. Obviously, the first step is to improve your iron deficiency and then figure out what happens. Your thyroid issues could solely be because of the iron and ferritin deficiency that you have. Ferritin 33ng/ml very low Ferritin is a component of a red blood cell. When ferritin is low you can feel fatigued and weak. Ferritin is also needed to the binding of thyroid hormones to cells so that it can stimulate metabolic function. Other signs include: Minor aches Abdominal pains Increased pulse or palpitations, Loss of libido Increased irritability and confusion Heartburn Numbness or tingling in extremities. Decrease in mental sharpness Paleness of the skin or eyes Brittle nails As mentioned above, with both iron and ferritin being low, this is a sign of iron deficiency anemia. When you are low in iron, you can feel tired, run down, not think clearly and restless leg syndrome. You can either not absorb the iron due to chronic inflammation in the GI tract or your diet may be deficient in iron.

6 MCV 100 is elevated: This means that you have a B12 deficiency and I would also recommend taking folic acid. When this is elevated combined with the low ferritin, it makes it difficult for your blood to carry oxygen, as it should. This can lead to excessive free radical damage. 2 nd Priority: We need to improve cortisol regulation: Cortisol 19.4 When cortisol is elevated it disrupts thyroid and sex hormone production. In addition, elevated cortisol causes more histamine to be released in the gut which then leads to food sensitivities and allergies. So cortisol will cause leaky gut and then lead to growing unfriendly flora such as candida (You are familiar with this). Also when elevated stress hormones occur over time, you can begin to get agitated mid day, and at the end of the day you may not feel as though you can think as sharply or have as good of critical thinking and coping skills. 3rd Priority Healing the Gut MEB value 25% with Eosinophils 14% both very elevated As you know there is a correlation to endurance athletes and GI problems. You have a history of GI distress. When cortisol becomes elevated, it fires the sympathetic nervous system. This causes a change in intestinal permeability. The gut becomes leaky and the result is an increase in inflammatory signaling through out the body. With more histamine being released your body becomes prone for more food and environmental intolerances to occur. 4 th Priority Build up protein intake through the day. Protein will help with anabolic drive and repair. It will also help with building thyroid hormones and brain neurochemicals. 5 th Priority Thyroid hormone balance TSH 2.43 (trending high) T4.98 (low normal) Free T3 2.5 (low) There are two issues driving the low thyroid performance and potentially a third. Correcting the first two may take of the problem but we will have to consider all of the following. Iron and ferritin deficiency

7 Elevated Cortisol Other trace mineral deficiencies that I suspect (chromium, tyrosine, Selenomethionine, iodine and magnesium) All of the products I am recommending for you are vegan and are in veggie cap. You can order these from my LMI office or get them some of them through LifeTime. Call Fritz Geer my business partner He will set you up at my cost so it will be a big savings. Product a.m. noon p.m. bedtime Reason Ohirra s Probiotic (LMI Clinic) Quercetin Chalcone (Thorne) (LMI clinic) 1 2 High potency probiotic that decreases inflammation signaling. Do this dose for 4 weeks 2 2 This is to reduce histamine response, best to take before or between meals Moducare (Wakanaga) (LMI clinic) Relora Plus (lifetime has this) Methyl Guard (LMI Clinic) 2 Restores immune balance, reduces cortisol output in athletes 1 1 Stress Response, feel more calm during the day 1 1 B12 and Folate deficiency Floradix 1 dose 1 dose 1 dose This provides 30 mg/day.

8 Meriva SR 500mg (LMI clinic) Multivitamin whichever one you are currently using. GlutAloemine (LMI clinic) Veggie Protein from Lifetime We should recheck iron and ferritin levels in 4 6 weeks Decreases inflammation in the intestine and reduces inflammatory markers in the blood stream. 1 tsp 1 tsp Help restore the gut lining, protect the kidneys and immune system. 1 serving 1 serving Mix this in some almond milk. Look on the label make sure the brand doesn t have carrageenan in it. This is to build your amino acid pool up.