Section 3: Hazardous Ingredients Name CAS# % by Weight TLV/PEL LC50 / LD 50

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Material Safety Data Sheet DOT HCS Risk Phrases Protective Clothing Not a controlled substance Section 1: Product Identification and Uses Common/Trade name (4469.23) Synonyms Bovine Rhinotracheitis-Virus Diarrhea Parainfluenza Respiratory Syncytial Virus Vaccine, Modified Live Virus, Leptospira Canicola- Grippotyphosa-Hardjo-Pomona Baceterin, icterohaemorrhagiae CI# TSCA No products found Chemical name Chemical formula Chemical family Supplier Material uses CAS# Code MSDS ID#: 4469.23 Molecular weight. Boehringer Ingelheim Vetmedica, Inc. 2621 North Belt Hwy St. Joseph MO 6456-22 Vaccine Manufacturer Boehringer Ingelheim Vetmedica, Inc. 2621 North Belt Hwy St. Joseph MO 6456-22 816-233-2571 Section 2: First Aid Measures Eye contact Skin contact Hazardous skin contact Slight inhalation Hazardous inhalation Slight ingestion Hazardous ingestion Flush eyes with copious amounts of water. Not considered a skin irritant. After contact with skin, wash immediately with plenty of water. If irritation occurs, seek immediate medical attention. No information regarding inhalation. Seek medical attention. No information available regarding ingestion. Notify physician or Poison Control Center immediately.. Section 3: Hazardous Ingredients Name CAS# % by Weight TLV/PEL LC5 / LD 5 Thimerosal 54-64-8.1% LD5, Oral, Rat 75 mg/kg, Oral LD5 Acute: 142 mg/kg Rabbit Neomycin Sulfate 145-1-3 No more than 3 mcg per dose Formaldehyde 5-- <.2%.75 ppm TWA STEL: 2 Page 1 of 4 ORAL (LD5): Acute: 8 mg/kg (Rat), Dermal (LD5): Acute: 27 mg/kg (Rabbit), DUST (LD5): Acute: 724.7 mg/m 3 4 hour(s) (Rat).

Section 4: Physical Data Physical state and appearance PH (1% soln/water) Odor threshold Volatility Melting/Sublimation point Boiling/Condensation point Specific gravity Vapor density Vapor pressure Water/oil dist. Coeff. Ionicity (surface active agent) Critical temperature Instability temperature Conditions of instability Dispersion properties Solubility Liquid diluent. White freeze-dried cake. Odor. Approximate range of 6.5 to 7.5 Taste.. Color White opaque. (MLV portion freeze-dried cake in amber bottle).............. Section 5: Fire and Explosion Data The product is: Auto-ignition temperature Not flammable.. Fire degradation products Flash points Flammable limits Fire extinguishing procedures Flammability Risks of explosion.... Not flammable.. Page 2 of 4

Section 6: Data Stability Hazardous decomp. products The product is stable. None known. Degradability Product of degradation Corrosivity.. No specific information is available in our database regarding the corrosivity of this product in the presence of various materials. No known incompatibilities. Section 7: Toxicological Properties Routes of entry TLV Accidental injection.. Toxicity for animals LD5:. LC5:. Chronic effects on humans Carcinogenic Effects: Classified A2, suspected for humans, by ACGIH (formaldehyde) Mutagenic Effects: Teratogenic Effects: Developmental Toxicity: Proven (formaldehyde) Acute effects on humans Not for human use. Animal injection only, accidental injection to humans can cause serious local reactions. Contact a physician immediately if accidental injection occurs. Section 8: Preventive Measures Waste information Waste stream Storage Precautions Small spill and leak Large spill and leak Protective Clothing Dispose of in accordance with all City, State and Federal regulations.. Store out of direct sunlight at a temperature between 35-45 degrees F (2-7 degrees C). Avoid freezing. Shake well before using. Use entire contents when first opened. For formaldehyde, neutralize with sodium bidulfite. Absorb with an inert material and place in an appropriate waste disposal container. Goggles Page 3 of 4

Section 9: Classification DOT Not a DOT controlled material (United States). Not applicable. Maritime transportation. HCS Not a controlled substance Federal and State Regulations Not applicable HMIS (U.S.A.) Health Hazard Fire Hazard Personal Protection 1 n National Fire Protection Association (U.S.A.) Fire Hazard 1 Specific hazard Section 1: Protective Measures Protective clothing Splash goggles Engineering controls No special ventilation requirements. Section 11: Other Information References. Validated by Company: 3/21/5 CALL 1(8) 821-7467 Emergency Medical: (8)53-5432 Chemtrec: (8)424-93 The information provided herein is offered by Boehringer Ingelheim Vetmedica, Inc. ( BIV ) in good faith as accurate as of the date hereof, but without guarantee. This information includes information which has been generated by other parties and provided to BIV, and which BIV has not independently verified. The information provided herein relates only to the specific product designated, and may not be valid where such product is used in combination with any other materials or in any process. The information provided herein is offered solely for your consideration, investigation and verification, and Boehringer Ingelheim Vetmedica, Inc. ( BIV ) expressly disclaims all liability for reliance thereon. BIV EXPRESSLY DISCLAIMS ALL WARRANTIES OF EVERY KIND AND NATURE (INCLUDING WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE) WITH RESPECT TO THE USE OR SUITABILITY OF THE PRODUCT. In addition, since the conditions of use and suitability of the product for particular uses are beyond BIV s control, ALL RISKS OF USE OF THE PRODUCT ARE THEREFORE ASSUMED BY THE USER, AND BIV EXPRESSLY DISCLAIMS ANY AND ALL LIABILITY AS TO ANY RESULTS OBTAINED OR ARISING FROM ANY USE OF THE PRODUCT. Use or retransmission of the information contained herein in any other format than the format as presented is strictly prohibited. Nothing herein shall be construed as a permission or recommendation for the use of the product in a manner that might infringe an existing patent. BIV neither represents nor warrants that the format, content or product formulas contained in this document comply with the laws of any other country except the United States of America. Copyright 21 Boehringer Ingelheim Vetmedica, Inc. All rights reserved. Page 4 of 4

The information provided herein is offered by Boehringer Ingelheim Vetmedica, Inc. ( BIV ) in good faith as accurate as of the date hereof, but without guarantee. This information includes information which has been generated by other parties and provided to BIV, and which BIV has not independently verified. The information provided herein relates only to the specific product designated, and may not be valid where such product is used in combination with any other materials or in any process. The information provided herein is offered solely for your consideration, investigation and verification, and Boehringer Ingelheim Vetmedica, Inc. ( BIV ) expressly disclaims all liability for reliance thereon. BIV EXPRESSLY DISCLAIMS ALL WARRANTIES OF EVERY KIND AND NATURE (INCLUDING WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE) WITH RESPECT TO THE USE OR SUITABILITY OF THE PRODUCT. In addition, since the conditions of use and suitability of the product for particular uses are beyond BIV s control, ALL RISKS OF USE OF THE PRODUCT ARE THEREFORE ASSUMED BY THE USER, AND BIV EXPRESSLY DISCLAIMS ANY AND ALL LIABILITY AS TO ANY RESULTS OBTAINED OR ARISING FROM ANY USE OF THE PRODUCT. Use or re-transmission of the information contained herein in any other format than the format as presented is strictly prohibited. Nothing herein shall be construed as a permission or recommendation for the use of the product in a manner that might infringe an existing patent. BIV neither represents nor warrants that the format, content or product formulas contained in this document comply with the laws of any other country except the United States of America. Copyright 21 Boehringer Ingelheim Vetmedica, Inc. All rights reserved. Disclaimer.doc