BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors. Follow this format for each person. DO NOT EXCEED FIVE PAGES. NAME: Norman L. Foster era COMMONS USER NAME (credential, e.g., agency login): nlfoster POSITION TITLE: Professor of Neurology, School of Medicine, University of Utah EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.) INSTITUTION AND LOCATION DEGREE (if applicable) Completion Date MM/YYYY FIELD OF STUDY MacMurray College B.A. 05/1973 Biology and Chemistry Washington University M.D. 05/1977 Medicine Jewish Hospital of St. Louis, Washington Univ Medical Center Intern 06/1978 Medicine University of Utah School of Medicine Resident 06/1981 Neurology National Institute of Neurological & Communicative Disorders Fellow 06/1984 Medical Therapeutics A. Personal Statement B. Positions and Honors Positions and Employment 1977-1978 Assistant in Medicine, Washington University School of Medicine, St. Louis, MO 1983-1984 Attending Physician, National Institutes of Health, National Institute of Neurological and Communicative Disorders and Stroke, Experimental Therapeutics Branch, Bethesda, MD 1984-2005 Attending Staff Physician, University Hospital, Ann Arbor, MI 1984-1991 Assistant Professor, University of Michigan Medical School, Department of Neurology, Ann Arbor, MI 1985-2002 Consultant and Attending Physician, Veterans Administration Hospital, Ann Arbor, MI 1991-1998 Associate Professor, University of Michigan Medical School, Department of Neurology, Ann Arbor, MI 1995-1997 Associate Research Scientist, University of Michigan, Institute of Gerontology, Ann Arbor, MI 1997-1998 Senior Associate Research Scientist, University of Michigan, Institute of Gerontology, Ann Arbor, MI 1998-2003 Senior Research Scientist, University of Michigan, Institute of Gerontology, Ann Arbor, MI 1998-2005 Professor, University of Michigan Medical School, Department of Neurology, Ann Arbor, MI Foster, Page 1
2003-2005 Research Professor, University of Michigan, Institute of Gerontology, Ann Arbor, MI 2005- Professor, University of Utah, Department of Neurology, Salt Lake City, UT 2005- Senior Investigator, University of Utah, The Brain Institute, Salt Lake City, UT 2005-2007 Adjunct Professor, University of Michigan, Department of Neurology, Ann Arbor, MI 2014- Adjunct Professor, Division of Otolaryngology, Department of Surgery, University of Utah, Salt Lake City, UT Other Experience and Professional Memberships 1985 Ad Hoc/Site Visitor, Site Visit Team, Aging Review Committee, National Institute on Aging 1985 Grant Review Committee/Study Section, Ad Hoc Review Committee, Alzheimer's Disease Research Centers, NIA 1985-1987 Grant Review Committee/Study Section, Special Reviewer, Sensory Disorders and Language Study Section, National Institutes of Health 1986 Grant Review Committee/Study Section, Ad Hoc Reviewer, National Institute on Aging 1987 Grant Review Committee/Study Section, Field Reader, FDA Orphan Products Development Grants Program 1988 Grant Review Committee/Study Section, Ad Hoc Review Committee, Alzheimer's Disease Research Centers, NIA 1988 Grant Review Committee/Study Section, External Reviewer, Veterans Administration Merit Grants 1989 Grant Review Committee/Study Section, Ad Hoc Reviewer, National Institute of Mental Health 1989 Grant Review Committee/Study Section, Special Review Group, Human Development and Aging Study Section, NIH 1999-2000 Grant Review Committee/Study Section, Special Emphasis Panel, NIA, Review of Grants for Alzheimer's Disease Pilot Clinical Trials 2000 Ad Hoc/Site Visitor, "A Tour and Overview of the Cognitive Disorders Clinic," Site Visit, Societal Analysis of Aging (HMP 673), School of Public Health, Jersey Liang, Ph.D., instructor 2001 Grant Review Committee/Study Section, Special Emphasis Panel, NIA, Review of Mentored Clinical Scientist Development Awards in Alzheimer's Disease and Related Dementias 2002 Grant Review Committee/Study Section, Ad Hoc Reviewer, NIH, Brain Disorders and Clinical Neuroscience-1 (BDCN-1) Study Section 2003 Grant Review Committee/Study Section, Grant Reviewer, General Clinical Research Center, University of Michigan 2003 Grant Review Committee/Study Section, Special Emphasis Panel, NIH, Brain Disorders and Clinical Neuroscience Initial Review Group (ZRG1- BDCN-1, 02) Foster, Page 2
2007-2011 Grant Review Committee/Study Section, Chartered Member, NIH, Center for Scientific Review, Clinical Neuroscience and Neurodegeneration (CNN) Study Section 2010-2011 Grant Review Committee/Study Section, Chair, NIH, Center for Scientific Review, Clinical Neuroscience and Neurodegeneration (CNN) Study Section 2011- Grant Review Committee/Study Section, Chartered Member, NIH/NIA, Neuroscience of Aging (NIA-N) Review Committee Honors 1977 Alpha Omega Alpha 1977 Upjohn Achievement Award 1983 Young Alumnus of the Year, MacMurray College 1985-1990 Clinical Investigator Development Award, NIH 1995 Doctor of Science (Honorary), MacMurray College 1996-2014 Elected by his peers for inclusion in Best Doctors in America 2007 Health Care Hero Award, Innovation category, Utah Business Magazine 2010 A Lifetime of Extraordinary Achievement (ALEXA) Award, Alzheimer's Association Utah Chapter C. Contribution to Science D. Research Support Ongoing Research Support Duff; Foster; Hoffman (PIs) 04/15/11-12/31/16 GE Healthcare Practice Effects and Amyloid Imaging using 18F-PIB (18F-39-F-6-OH-BTA1) known as [18FGE067]) or Flutemetamol PET and FDG-PET King (PI) 08/15/11-07/31/15 NIH/NIA/AFAR Cortical Complexity Changes in Normal Aging and Alzheimer's Disease (Beeson Career Development Award, K23 AG03835) Role: Mentor Weiner (PI) 09/01/11-08/31/15 NIH/NIA Alzheimer s Disease Neuroimaging Initiative (ADNI) 2, Utah Component: PET Imaging Core (2UD AG024904-06) Role: Site Principal Investigator Duff; Foster; Hoffman (PIs) 07/01/12-06/30/15 Foster, Page 3
Dana Foundation Amyloid Burden &Amp; Cog Training 1R41AG044147-01 Foster (PI) 09/30/12-Present National Institutes of Health The Memory Care Navigator: A Proactive Guide (1R41AG044147-01). Small Business Alzheimer's Disease Research (STTR[R41/R42]). Phase II, funding currently in review. Supiano (PI) 10/01/12-09/30/14 VA ORH (VA Salt Lake City Health Care System) VISN 19-660 Telehealth Enhanced Collaborative Geriatric Care [ProTEC] Role: Project Director, Proactive Memory Clinic Foster; King; Zamrini (PIs) 01/01/13-12/31/14 Hba Renewal Foster (PI) 02/28/13-02/28/14 Avid Radiopharmaceuticals A randomized, multicenter, multicountry study to evaluate the effectiveness of florbetapir (18F) PET imaging in changing patient management and to evaluate the relationship between florbetapir (18F) PET scan status and cognitive decline [18F-AV-45-A18] Duff; Foster; Hammers; Hoffman; King; Zamrini (PIs) 03/27/13-01/31/15 Quintiles Transnational Corporation 18f-Av-45-A18 Chelune; Foster (PIs) 03/28/13-03/27/14 VA Salt Lake City Health Care System Tecc Foster (PI) 07/11/13-07/31/13 GE Healthcare Ge Symposium Foster; King; Zamrini (PIs) 07/11/13-03/30/20 Merck & Company, Inc. Mk-8931 (Epoch) Foster, Page 4
Foster (PI) 12/01/13-11/30/16 TauRx Therapeutics Ltd. Trx-237-007 Foster (PI) 12/12/13-06/30/14 United Biosource Corporation Piramal-Ubc Florbetaben Pet Foster (PI) 03/28/14-03/30/16 VA Salt Lake City Health Care System Protec 2014 Foster (PI) 05/14/14-05/31/15 Piramal Life Sciences Piramal Consultancy Duff; Foster; Hammers; King; Zamrini (PIs) 08/28/14-08/31/16 EnVivo Pharmaceuticals, Inc. Evp-6124-024 Duff; Foster; Hammers; King; Zamrini (PIs) 08/28/14-08/31/16 EnVivo Pharmaceuticals, Inc. Evp-6124-026 Foster; King; Zamrini (PIs) 04/30/15-01/02/20 ASTRA-ZENECA Amaranth Azd3293 Foster (PI) 11/01/15-10/31/20 Patient-Centered Outcomes Research Institute Diabetes And Dementia, Awv Allen; Foster (PIs) 05/01/16-10/31/21 Foster, Page 5
Patient-Centered Outcomes Research Institute Procare Foster (PI) 08/16/16-07/31/19 Alzheimer's Association Ideas Foster; King (PIs) 11/01/16-10/31/21 Suven Life Sciences Ltd Suvn-502 Duff; Foster; Hammers; King (PIs) 07/01/17-12/31/21 DrugDev, Inc. Eisai E2609 Duff; Foster; Hammers; King (PIs) 07/01/17-06/30/23 Genentech Inc Crenezumab Foster (PI) 01/29/18-12/31/20 Eli Lilly And Company I8d-Mc-Azfd-Amaranth Ext Duff; Foster; Hammers; King (PIs) 01/31/18-01/31/24 Janssen Research & Development Llc Janssen A5 Allen; Foster (PIs) 04/01/18-03/31/20 University Of New Mexico Dementia Dialogue Interventio Foster (PI) 06/01/18-08/31/18 VA Salt Lake City Health Care System Va Pilot Program Ipa Foster (PI) 10/01/18-06/30/19 Foster, Page 6
Utah Department of Health Ad Community Care Consults Allen; Duff; Fisher; Foster; Greene; Supiano (PIs) 10/01/18-09/30/23 Procare R01 Foster (PI) 01/01/19-12/31/23 Biogen Biogen 221ad302 Foster (PI) 03/04/19-03/03/22 Inc Research Inc Trx-237-039 (Lucidity) Foster (PI) 01/01/20-12/31/25 Abbvie, Inc Abbv-8e12 Ext. Completed Research Support CTA 148-UTAH (NGF) M-00 ADCS House; King (PIs) 02/01/09-06/30/13 ADCS / University of California San Diego A Double-Blind, Placebo-Controlled (Sham Surgery), Randomized, Multicenter Study Evaluating CERE-110 Gene Delivery in Subjects with Mild to Moderate Alzheimer s Disease [CERE-110 in AD] Role: Co-Investigator Bristol-Myers Squibb BMS Diagnostic Adjudication Committee Role: Consultant Member 10/05/09-05/30/13 Foster (PI) 01/01/11-12/31/13 Center for Health Improvement Proactive Dementia Care Planning Foster, Page 7
Foster (PI) 01/01/13-12/31/13 Sorenson Legacy Foundation Extending Geropsychiatric Services to Patients with Cognitive Disorders in Southern Utah Foster, Page 8