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Continuing Medical Education Cardiology Symposium Cardiovascular Care for the Non-cardiologist University of South Carolina Greenville Memorial Medical Campus 607 Grove Road Floor 1, Lecture Hall Room 160 Sat., Jan. 28, 2017 7:00 a.m.-4:30 p.m. Sponsored by Greenville Health System in cooperation with Carolina Cardiology Consultants

Course Description The purpose of this educational activity is to update the primary care community on the latest advances in cardiovascular care. Through a combination of lectures, panel discussions and a live case broadcast, participants will be better equipped to evaluate patients with cardiac disease and assess treatment options. Planning Committee Members Jim R. Baucum, MD, FACC, Chairman Sarah M. Carter, MD David P. Guirao, MD Jesse P. Jorgensen, MD, FACC Timothy R. Malinowski, MD, FACC Maureen Coyne Stormi Harmon Theresa Varughese, BSN, RN Keynote Speaker Caldwell B. Esselstyn Jr., MD, FACS Dr. Esselstyn earned his undergraduate degree from Yale University and his medical degree from Western Reserve University. He was trained as a general surgeon at Cleveland Clinic and St. George s Hospital in London. Dr. Esselstyn has been associated with Cleveland Clinic since 1968. There, he has served as President of the Staff and as a member of the Board of Governors. He also has chaired the clinic s Breast Cancer Task Force and headed its Section of Thyroid and Parathyroid Surgery. He currently serves as the Cleveland Clinic Wellness Institute s director of cardiovascular prevention and reversal program. Dr. Esselstyn has published more than 150 scientific articles and has received many honors, including being named President of the American Association of Endocrine Surgeons, becoming the first recipient of the Benjamin Spock Award for Compassion in Medicine and receiving the 2013 Yale University George H.W. Bush 48 Lifetime of Leadership Award. Faculty Speakers Jim R. Baucum, MD, FACC Greenville Health System Andrew J. Brenyo, MD Greenville Health System A.H. (Trey) Chandler III, MD, FACC Greenville Health System Department of Medicine Carolina Cardiology Consultants; Clinical Assistant Professor, University of South Carolina Josh R. Doll, MD, FACC Greenville Health System Zachary H. George, MD, FACC Greenville Health System Jason L. Guichard, MD, PhD University of Alabama at Birmingham, Division of Cardiovascular Disease; Advanced Heart Failure and Transplant Cardiology Fellow Jesse P. Jorgensen, MD, FACC Greenville Health System Timothy R. Malinowski, MD, FACC Greenville Health System Department of Medicine Carolina Cardiology Consultants; President, Greenville Health System Medical Staff; Clinical Assistant Professor, University of South Carolina Joseph A. Manfredi, MD, FACC, FHRS Greenville Health System Department of Medicine Carolina Cardiology Consultants; Clinical Assistant Professor, University of South Carolina Peter C. Netzler, MD Greenville Health System Chetan A. Patel, MD Greenville Health System Dev G. Vaz, MD, FACC Greenville Health System

AGENDA 8:00-8:05 a.m. Welcoming Remarks A.H. (Trey) Chandler III, MD, FACC 8:05-9:05 a.m. Keynote Address: The Nutritional Reversal of Cardiovascular Disease: Fact or Fiction Caldwell B. Esselstyn Jr., MD, FACS 9:05-9:15 a.m. Keynote Q&A SESSION 1 HEART FAILURE Moderator: Jesse P. Jorgensen, MD, FACC 9:15-10:00 a.m. Mechanical Circulatory Support Programs: The Rise of Durable Left Ventricular Assist Devices (LVADs) Jason L. Guichard, MD, PhD 10:00-10:05 a.m. Session 1 Q&A 10:05-10:20 a.m. Break 10:20-10:40 a.m. Guideline-directed Medical Therapy for Heart Failure: 2017 Update Dev G. Vaz, MD, FACC 10:40-11:00 a.m. Device-based Therapy: Who, What and When? Joseph A. Manfredi, MD, FACC, FHRS 11:00-11:10 a.m. Session 1 Q&A SESSION II STRUCTURAL HEART Moderator: Timothy R. Malinowski, MD, FACC 11:10-11:30 a.m. Hypertrophic Obstructive Cardiomyopathy: Symptom Management Josh R. Doll, MD, FACC 11:30-11:50 a.m. Absorb Stent: A Niche Device or the New Standard? Zachary H. George, MD, FACC 11:50 a.m.-12:10 p.m. Aortic Valve Replacement: Sternotomy Is History Jesse P. Jorgensen, MD, FACC 12:10-12:20 p.m. Session II Q&A 12:20-1:10 p.m. Lunch Break

1:10-2:10 p.m. Live Broadcast: Septal Ablation Josh R. Doll, MD, FACC SESSION III ATRIAL FIBRILLATION Moderator: Jim R. Baucum, MD, FACC 2:10-2:30 p.m. The Age of the Novel Oral Anticoagulants Peter C. Netzler, MD 2:30-2:50 p.m. Left Atrial Appendage Occlusion: Watch This Chetan A. Patel, MD 2:50-3:10 p.m. Ablation in the Video Game Era Andrew J. Brenyo, MD 3:10-3:20 p.m. Session III Q&A 3:20-3:35 p.m. Break SESSION IV CASE REVIEW Moderator: Jesse P. Jorgensen, MD, FACC 3:35-3:55 p.m. Case Study: Need to Chill Treatment Strategies for Resuscitated Cardiac Arrest Presentations Jim R. Baucum, MD, FACC 3:55-4:15 p.m. Hey, Check This Out! Interesting Case Presentations: Cardiac Imaging Timothy R. Malinowski, MD, FACC 4:15-4:25 p.m. Q&A 4:25-4:30 p.m. Closing Remarks Accreditation The Greenville Health System (GHS) designates this Live activity for a maximum of 7.0 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. The Greenville Health System is accredited by the South Carolina Medical Association to provide continuing medical education for physicians.

Educational Objectives Identify the cause of cardiovascular disease and how to halt and reverse it Define advanced heart failure and risk factors for increased heart failure mortality Describe components of a mechanical circulatory support program and identify appropriate candidates for advanced heart failure therapies Summarize the current evidence for durable left ventricular assist devices Review the American College of Cardiology and the American Heart Association clinical practice guidelines and incorporate the most recent updates Identify when a patient is most likely to benefit from device therapy Discuss the role of invasive treatments in the management of hypertrophic cardiomyopathy Differentiate absorbable stents from drug-eluting stents and bare metal stents, including their clinical indications and characteristics Describe the clinical outcomes, benefits and risks of TAVR compared to surgical aortic valve replacement; identify future applications of transcatheter therapies Demonstrate alcohol septal ablation procedure for hypertrophic cardiomyopathy Describe the rationale for novel anticoagulation use and identify candidates. Summarize methods of stroke prophylaxis in atrial fibrillation, including anticoagulation and left atrial appendage occlusion devices Describe the role and benefit of modern technology on ablation therapy Review treatment strategies for resuscitated cardiac arrest presentations, including rationale for and methods to achieve systemic hypothermia Demonstrate the value and capabilities of various forms of cardiac imaging Participants will be better equipped to evaluate patients with cardiac disease and assess treatment options.

Registration for Symposium Fee: $100 for physicians and advanced practitioners (no charge for GHS employees and medical students) To register for the symposium and pay online, please visit the GHS CME website at www.university.ghs.org/cme/conferences. For registration inquiries, please contact the CME offices at (864) 455-3546 or cme@ghs.org.

Continuing Medical Education c/o Academic Services 701 Grove Road Greenville, SC 29605 Non-Profit Org. US Postage PAID Greenville SC Permit No. 842 ADDRESS SERVICE REQUESTED Sponsored by Greenville Health System In cooperation with... Carolina Cardiology Consultants Cardiology Symposium Sat., Jan. 28, 2017 To register for the symposium and pay online, please visit the GHS CME website at www.university.ghs.org/ CME/Conferences. 17-0006 11/16