EPI 220: Principles of Infectious Disease Epidemiology UCLA School of Public Health https://ccle.ucla.edu/course/ Syllabus Winter 2016

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EPI 220: Principles of Infectious Disease Epidemiology UCLA School of Public Health https://ccle.ucla.edu/course/ Syllabus Winter 2016 Course information Time: Tuesdays and Thursdays 4-5:50 PM Location: 33-105 CHS Units: Instructor: Roger Detels, MD, MS Professor, Epidemiology and Infectious Diseases UCLA Schools of Public Health and Medicine 71-269 CHS Los Angeles, California 90095-1772 Office phone: (310) 206-2837 detels@ucla.edu Office Hours: TA (Joshua Quint) TBD Reading Selection Supplemental reading will be available on the syllabus for individual lectures COURSE OBJECTIVES: After taking this course students will be able to: 1. Describe and understand the main epidemiological characteristics of the major infectious diseases of humans 2. Know the terms/vocabulary used to describe infectious agents and the natural history of infection by them 3. Understand the human immune system s response to infection by an infectious agent 4. Know epidemiological characteristics of infectious agents, such as incubation period, infectious period, means of transmission, and reservoir of these infectious diseases 5. Identify strategies used in the investigation of an existing or newly emerging or re-emerging infectious disease 6. Describe the objectives and methods used to investigate an outbreak 7. Describe how epidemiological characteristics can be utilized to develop and evaluate strategies to prevent epidemics or endemic transmission of the major infections of humans 8. Recommend effective interventions for the major infectious diseases 9. Understand the economic, social, and political impact of infectious diseases

Principles of Infectious Disease Epidemiology Epi 220 Winter 2016 Tuesdays and Thursdays, 4:00-5:50 p.m. 33-105 CHS Please note that there may be occasions when scheduling changes need to be made. In addition, we cannot guarantee that PPT presentations will always be available online before class. TEXTBOOK HOLD: The Biomed library currently has "Control of Communicable Diseases Manual" available to the class. Go to the reserves desk with your student ID for a 2-hour checkout period for this book. The library will purchase "Infectious Disease Epidemiology: Theory and Practice", so that probably won't be available until late January. Tues History, Current Major Infectious Disease Problems R. Detels Jan 5 Wk 1 Thurs Classifications, Modes of Spread and Infection, R. Detels Jan 7 and Properties of Agents Tues The Human Immune Response T. Rickabaugh Jan 12 Wk 2 Geographic Information Systems D. Morales Thurs Jan 14 Tues HIV/AIDS R. Detels Jan 19 Wk 3 Thurs Sexually Transmitted Infections J. Klausner Jan 21 Tues Epidemiologists and Laboratory Science N. Aziz Jan 26 Wk 4 Thurs Surveillance & Transmission R. Detels Jan 28 Tues Emerging and Re-emerging Diseases R. Detels Feb 2 Wk 5 Thurs Respiratory Infections, Diarrhea and Influenza R. Detels Feb 4

Tues Tuberculosis S. Shin Feb 9 Wk 6 Thurs MID-TERM EXAMINATION Feb 11 Tues Viral Hepatitis A, B, and C R. Detels Feb 16 Wk 7 Thurs Modeling Infectious Diseases R. Brookmeyer Feb 18 Tues Staphlococci and Streptococci in the Context of S. Shafir Feb 23 Hospital-Associated Infections Wk 8 Thurs Malaria F. Sorvillo Feb 25 Tues Parasitic Diseases L. Ash Mar 1 Wk 9 Thurs Human Papilloma Virus and New Lab Testing R. Detels Mar 3 Tues Arboviral Diseases R. Detels Mar 8 Wk 10 Thurs Infectious Disease Interventions/Vaccines R. Detels Mar 10 TUESDAY Mar 15 3-6 PM Grading FINAL EXAMINATION Midterm exam = 33.3% of total grade if better than final Final exam = 66.7% of total grade if worse than midterm; else, final grade only Course Description Infectious diseases remain a major cause of morbidity and mortality, especially in developing countries, and are the major cause in the countries of sub-saharan Africa. Lower respiratory diseases and diarrhea are the leading causes of death in children in developing countries. Even developed countries are impacted by newly emerging and re-emerging infectious diseases such as HIV/AIDS, Ebola, and measles. This course presents the major characteristics of infectious diseases, strategies for control, and public health aspects of their occurrence and prevention. The biology and public health issues of currently important diseases and key infectious disease strategies, including surveillance and laboratory assessment, will be presented to the class. Student performance will be assessed by mid-term and final examinations. The course is required for epidemiology majors who do not have a medical background. Students are advised to have taken at least one course in epidemiology before enrolling.

Learning Objectives and Competencies Upon completion of this course, you should be able to demonstrate the skills listed as Course Learning Objectives below. These learning objectives were selected to help you build competencies required for the MPH program (see http://ph.ucla.edu/current-students/programmatic-competencies). COURSE LEARNING OBJECTIVES 1. Describe and understand the main epidemiological characteristics of the major infectious diseases of humans F5. Demonstrate effective written and oral skills for communicating with different audiences in the context of professional public health activities. critique and interpret epidemiological studies, including their strengths and weaknesses. J3. Identify key sources of data for epidemiologic purposes. J4. Identify the principles and

2. Know the terms/vocabulary used to describe infectious agents and the natural history of infection by them F4. Collaborate with communication and informatics specialists in the process of design, implementation, and evaluation of public health F5. Demonstrate effective written and oral skills for communicating with different audiences in the context of professional public health activities. F8. Engage in dialogue and learning from others to advance public health goals. D8. Communicate epidemiologic critique and interpret epidemiological studies, including their strengths and weaknesses. 3. Understand the human immune system s response to infection by an infectious agent D8. Communicate epidemiologic critique and interpret epidemiological studies, including their strengths and weaknesses.

4. Know epidemiological characteristics of infectious agents, such as incubation period, infectious period, means of transmission, and reservoir of these infectious diseases F8. Engage in dialogue and learning from others to advance public health goals. D8. Communicate epidemiologic critique, and interpret epidemiological studies, including their strengths and weaknesses. J3. Identify key sources of data for epidemiologic purposes. J4. Identify the principles and

5. Identify strategies used in the investigation of an existing or newly emerging or re-emerging infectious disease F1. Understand the concepts of human subject protection and confidentiality. F2. Recognize ethical issues that arise in epidemiological research. F7. Identify public health programs and strategies that are responsive to the diverse cultural values and traditions of the communities being served. F13. Describe basic principles of ethical analysis (e.g., the Public Health Code of Ethics, human rights framework, other moral theories) as they relate to issues of public health practice and policy. D2. Identify the principles and critique, and interpret epidemiological studies, including their strengths and weaknesses. J7. Draw appropriate inferences from J9. Behave in an ethical manner in the dissemination of J10. Identify, explain and apply epidemiologic principles and methods in a research, public health, or community setting.

6. Describe the objectives and methods used to investigate an outbreak F1. Understand the concepts of human subject protection and confidentiality. F2. Recognize ethical issues that arise in epidemiological research. F7. Identify public health programs and strategies that are responsive to the diverse cultural values and traditions of the communities being served. D5. Comprehend basic ethical and legal principles pertaining to the dissemination of D8. Communicate epidemiologic critique, and interpret epidemiological studies, including their strengths and weaknesses. J8. Effectively communicate orally and in writing epidemiologic J9. Behave in an ethical manner in the dissemination of J10. Identify, explain and apply epidemiologic principles and methods in a research, public health, or community setting.

7. Describe how epidemiological characteristics can be utilized to develop and evaluate strategies to prevent epidemics or endemic transmission of the major infections of humans F1. Understand the concepts of human subject protection and confidentiality. F2. Recognize ethical issues that arise in epidemiological research. F7. Identify public health programs and strategies that are responsive to the diverse cultural values and traditions of the communities being served. and place D4. Explain the importance of epidemiology for informing scientific, ethical, economic and political discussion of health issues. D8. Communicate epidemiologic critique, and interpret epidemiological studies, including their strengths and weaknesses. J4. Identify the principles and J7. Draw appropriate inferences from J8. Effectively communicate orally and in writing epidemiologic J9. Behave in an ethical manner in the dissemination of J10. Identify, explain and apply epidemiologic principles and methods in a research, public health, or community setting.

8. Recommend effective interventions for the major infectious diseases F1. Understand the concepts of human subject protection and confidentiality. F2. Recognize ethical issues that arise in epidemiological research. F7. Identify public health programs and strategies that are responsive to the diverse cultural values and traditions of the communities being served. D2. Identify the principles and programs and place D4. Explain the importance of epidemiology for informing scientific, ethical, economic and political discussion of health issues. F8. Engage in dialogue and learning from others to advance public health goals. critique, and interpret epidemiological studies, including their strengths and weaknesses. J3. Identify key sources of data for epidemiologic purposes. J4. Identify the principles and J7. Draw appropriate inferences from J8. Effectively communicate orally and in writing epidemiologic J9. Behave in an ethical manner in the dissemination of J10. Identify, explain and apply epidemiologic principles and methods in a research, public health, or community setting.

9. Understand the economic, social, and political impact of infectious diseases F7. Identify public health programs and strategies that are responsive to the diverse cultural values and traditions of the communities being served. D2. Identify the principles and D4. Explain the importance of epidemiology for informing scientific, ethical, economic and political discussion of health issues. D5. Comprehend basic ethical and legal principles pertaining to the dissemination of critique and interpret epidemiological studies, including their strengths and weaknesses. J3. Identify key sources of data for epidemiologic purposes. J7. Draw appropriate inferences from