Health Concern Guilford County Department of Public Health Community Health Assessment

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9 212-213 Guilford County Department of Public Health Community Health Assessment Health Concern Sexually Transmitted Infections Chlamydia is the most common bacterial STI in North America [1] and in Guilford County, and is one of the major causes of tubal infertility, ectopic pregnancy, pelvic inflammatory disease and chronic pelvic pain. [2] STIs in general are associated with significantly increased risk of morbidity and mortality, including increased risk of cervical cancer, pelvic inflammatory disease, involuntary infertility and premature death. [1] One review found that close to onethird of pregnant teens were infected with at least one STI [2]. Both STIs and unintended pregnancies can result from the improper use of, inconsistent use of or lack of use of condoms, factors exacerbated by the fact that 4 out of 5 pregnancies are unintended. [3] STIs present significant issues for the health of residents of Guilford County. Rates of chlamydia, gonorrhea, syphilis and HIV disease are consistently higher in Guilford County than in the state as a whole and the nation. Large racial disparities exist for STIs, with African Americans experiencing rates as much as ten times that among whites. Higher rates of HIV disease are concentrated in census tracts in southeast Greensboro. Syphilis rates are higher in tracts in southeast and west Greensboro and areas of central High Point. The problem of STIs is also concentrated among teens and young adults. Highlights The most commonly occurring communicable diseases in Guilford County are sexually transmitted infections (STIs), with chlamydia contributing the largest number of cases (3,919 cases in 212), followed by gonorrhea (1,433 cases in 212) and non-gonococcal urethritis (NGU) (146 cases in 212). Cases of HIV disease decreased from 128 cases in 211 to 12 cases in 212; Guilford County s HIV disease rate is higher than that of NC as a whole. Cases of primary and secondary syphilis decreased from 57 cases in 211 to 45 new cases in 212. Young adult men are most at risk for contracting syphilis and HIV disease. Substantial racial disparities are seen in incidence rates for chlamydia, gonorrhea, syphilis and HIV disease, with Blacks/African Americans experiencing higher rates than Whites. HEALTHY NORTH CAROLINA 22 SEXUALLY TRANSMITTED DISEASES Objective: Reduce the crate of new HIV infection diagnoses (per 1, population). Rationale for selection: An estimated 35, North Carolinians have HIV/AIDS (including those who are unaware of their status). Furthermore, HIV/AIDS was the seventh leading cause of death among 25 to 44 year-olds in 27. NC BASELINE (29): 24.7 22 TARGET: 22.3 GUILFORD (NC DHHS 212): 2.4 http://publichealth.nc.gov/hnc22/docs/hnc22- FINAL-March-revised.pdf Inside this Chapter Syphilis Cases in Guilford County, by Race, Age and Gender Trends in Syphilis Incidence HIV Disease in Guilford County, by Race, Age and Gender Trends in HIV Disease Peer County Comparisons Trends in Chlamydia Incidence Trends in Gonorrhea Incidence 68

Guilford County Syphilis Cases, by Race, 212 Diseases African- American White Syphilis (Primary & Secondary) 31 3 Syphilis (Primary, Secondary & Early Latent) 58 7 Guilford County Syphilis Rate per 1,, by Race, 212 Diseases African- American White Syphilis (Primary & Secondary) 18.5 1.1 Syphilis (Primary, Secondary & Early Latent) 34.6 2.3 212 Population 167,488 296,91 Source: Communicable Disease Branch, NC Division of Public Health, NCDHHS. Demographic Characteristics of Guilford County Syphilis Cases, 212: Sex and Age 1 Percent 8 6 4 2 4.5 1-19 39.4 34.8 2-29 3-39 15.2 4-49 4.5 1.5 5-59 6-69 69

Syphilis incidence rates in Guilford County are higher in census tracts with greater numbers of non-white and lower income residents. Guilford s 212 Primary and Secondary Syphilis new case rate of 7.1 represents a 42.% increase in the 27 5. rate observed as baseline during the 29-21 Community Health Assessment. Primary and Secondary Syphilis Rates in North Carolina, Guilford and Peer Counties per 1, Population, 26-21 Residence Total White non- African-American Other non- non- Cumberland 4.4 1.4 13.6 Durham 8.5 4.7 16.1 3.1 1.3 Forsyth 13.6 3.3 43.2 4.9 Guilford 7.2 2. 18.2 4.1 1.3 Mecklenburg 1.3 3.2 27.5.5 3.4 Wake 4.7 2.2 14.5 2.7 North Carolina 4.1 1.4 13.8 1.1 1.9 Source: County Health Databook, NC DHHS, State Center for Health Statistics. Among Guilford peer counties, the highest rates of syphilis in 26-21 were found Forsyth, followed by Mecklenburg. As with other sexually transmitted conditions, there is a major racial disparity, with African- American having much higher incidence rates across all peer counties. 7

Trends in Primary and Secondary Syphilis Rates Guilford County, NC and United States 1991-212 Rate per 1, 45 4 35 3 25 2 15 1 5 7.1 3.6 Guilford NC US Source: General Communicable Disease Control Branch; Division of Public Health, NC DHHS Trends in Primary and Secondary Syphilis Rates By Race, Guilford County 1991-212 16 14 12 1 8 6 Rate per 1, 4 2 15.7 1 Whites Other Races Source: General Communicable Disease Control Branch; Division of Public Health, NC DHHS; Major disparities exist with respect to sexually transmitted diseases in Guilford County. Incidence rates for HIV Disease and syphilis are much higher for African-Americans than for whites. 71

HIV Disease Cases and Rate per 1,, by Race, 212 Diseases African-American White New Cases 71 22 Rate per 1, population 42.4 7.4 212 population 167,488 296,91 Source: Communicable Disease Branch, NC Division of Public Health, NCDHHS. Demographic Characteristics of Guilford County HIV Disease Cases, 212: Sex and Age Percent 1 8 6 79.4 Percent 1 8 6 4 2 Male 2.6 Female 4 2 2.9 23.5 26.5 28.4 1.8 6.9 1-19 2-29 3-39 4-49 5-59 6-69 7 and Older 1 As with syphilis, HIV incidence rates are higher in non-white, lower income census tracts, particularly in southeast Greensboro. The HIV Disease new case rate of 42.4 in 212 represents a 41.3% increase in the rate of 36. recorded in 27 at baseline from the 29-21 Community Health Assessment. 72

Trends in HIV Disease Incidence Rates Guilford County and North Carolina 1995-212 Rate per 1, 6 5 4 3 2 1 2.6 14.6 Guilford NC Source: HIV/STD Prevention & Care Branch, Division of Public Health, NC DHHS. Note: HIV Disease includes both new cases of HIV or AIDS Guilford County HIV incidence rates still exeed North Carolina s rates. Trends in HIV Disease Mortality Rates Guilford County and NC 1994-212 Rate per 1, 25 2 15 1 5 2.8 3. Guilford County North Carolina Source: NC Center for Health Statistics; Note: HIV Disease includes all cases of HIV and AIDS There has been a substancial decline in HIV mortality rates in both Guilford County and North Carolina over time, but the decline in HIV incidence has not been as significant. 73

Trends in Chlamydia Incidence Rates Guilford County, NC and United States 1992-212 12 1 Rate per 1, 8 6 4 797.1 524.1 457.6 2 Guilford NC US Source: General Communicable Disease Control Branch; Division of Public Health, NC DHHS Chlamydia rates declined in 212 after a significant increase in 211. Trends in Chlamydia Incidence Rates By Race, Guilford County 1992-212 Rate per 1, 25 2 15 172.2 1 5 159.3 White Other Races Source: General Communicable Disease Control Branch; Division of Public Health, NC DHHS; North Carolina Electronic Disease Surveillance System (NCEDSS).. Gonorrhea Rates per 1, Populations, 26-21, Guilford Peer Counties 74

County of Residence Total White non- African American, non- Other, non- Source: County Health Databook, NC DHHS, State Center for Health Statistics. Cumberland 168.9 52.9 581.6 96.7 54.2 Durham 272. 8. 61. 51.6 59.7 Forsyth 226. 68.9 686.3 79.7 57.3 Guilford 245.1 64.4 629.9 65.6 75.7 Mecklenburg 195.9 53.8 541.7 32. 38.4 Wake 141.8 36.5 537.3 33.3 65.1 North Carolina 168.9 52. 581.6 96.7 54.2 Among peer counties, the highest five-year rates of gonorrhea incidence occurred in Guilford County, followed by Forsyth counties. Guilford s rate was 45% higher than the state as a whole Major racial disparities are seen in all peer counties, with African-American rates as much as ten times the rates for whites. s tend to have similar rates as whites or lower. Guilford s 212 Gonorrhea new case rate of 297.4 per 1, is a 19.5% improvement compared to the 369.6 rate at baseline in 27 as observed during the 29-21 Community Health Assessment. Trends in Gonorrhea Incidence Rates Guilford County, NC and United States 1992-212 5 45 4 35 3 25 2 15 1 5 Rate per 1, 297.4 148.3 14.2 Guilford NC US Source: General Communicable Disease Control Branch; Division of Public Health, NC DHHS; 75

18 16 14 12 1 8 6 4 2 Trends in Gonorrhea Incidence Rates By Race, Guilford County 1992-212 Rate per 1, 664.7 38.7 White Other Races Source: General Communicable Disease Control Branch; Division of Public Health, NC DHHS; North Carolina Electronic Disease Surveillance System (NCEDSS).. References: [1] Genuis, SJ, Genuis SK. Managing the sexually transmitted disease pandemic: A time for reevaluation. Am J Obstet Gynaecol. 24; 191:117-122. [2] Centers for Disease Control and Prevention. Sexually Transmitted Disease Surveillance 21. Atlanta: U.S. Department of Health and human Services; 211. [3] Finer, LB, Zolna MR. Unintended pregnancy in the United States: Incidence and Disparities, 26.Contraception, 211 November; 84 (5) 478-485. 76