GLOBAL AND REGIONAL SITUATION OF AVIAN INFLUENZA Dr Gounalan Pavade OIE Regional Expert Group Meeting for the Control of Avian Influenza in Asia Sapporo, Japan 3-5 October 2017 1
Avian influenza Outbreaks of avian influenza continue to be a global public health concern (2458 human infections) and animal health concern (killed and destruction of millions and millions of poultry) HPAI is a disease of global interest due to the continued increase in the number of affected countries (80 countries) and subtypes (14 strains) The disease continue to be a top priority topic at international coordination and cooperation through joint collaboration with WHO and FAO 2
Legal obligation for AI disease notification in animals 181 Member Countries in 2017 Legal obligation for all Member Countries to report to the OIE One of the main missions of the OIE is to ensure transparency of worldwide animal disease situation including zoonosis 3
World Animal Health Information system (WAHIS) WAHIS provides a platform for collection, submission & access all data provided by countries An official OIE disease reporting format for clear & concise exchange of information Focal points under the responsibility of the Delegate, can submit information to the OIE 4
Global situation (Jan 2016 to March 2017) 154 countries/territories provided information on the disease, and 38% (59/154) reported the disease as present. Represent the highest number of countries affected since 2006 crisis. 56 countries/territories reported HPAI by means of immediate notifications, and 13% of them (7/56) reported the disease using as reason for notification first occurrence in the country. 5
Global situation (Jan 2016 to March 2017) The most common was subtype H5N8 (in 35 countries/territories in Africa, Asia, Europe and the Middle East), followed by subtype H5N1 (in 18 countries/territories in the Africa, Asia, Europe and the Middle East), subtype H5N5 (in eight countries in Europe), H5N6 (in seven countries/territories in Asia), H5N2 (in three countries in the Americas, Asia and Europe), H5N3 (in Chinese Taipei), H5N9 (in France), H7N1 (in Algeria), H7N3 (in Mexico), H7N7 (in Italy), H7N8 (in the United States of America) and H7N9 (in China). For the first time since 1998, the subtype notified by the highest number of countries at global level was H5N8 and not H5N1 6
Global impact (Jan 2016 to March 2017) The global impact of the disease on animal and public health during the reporting period (2016 and early 2017) was huge. Almost 18,000,000 poultry were destroyed during this period, while 118 human deaths were registered (3 due to H5N1 and 115 due to H7N9 subtypes). For these reasons, sustained efforts to monitor avian influenza must be seen as a primary objective, in both domestic and wild birds 7
HPAI outbreaks (2016/2017) 05/09/2017 8
Global situation for on-going outbreaks of HPAI in poultry and wild birds by strain (18 Sept 2017) Strain Count of countries affected # of ongoing outbreaks in poultry # of ongoing outbreaks in wild birds Aggregated count of poultry destroyed for ongoing outbreaks H5N1 8 17 0 131 168 H5N2 1 182 1 1 617 816 H5N5 2 0 2 0 H5N6 3 358 0 25 096 648 H5N8 16 277 51 4 355 879 H7N9 1 22 0 831 087 Total 31 856 54 32 032 598 9
Epidemic curve showing the weekly incidence of outbreaks of HPAI since October 2016 300 250 200 150 100 50 0 w1 w2 w3 w4 w1 w2 w3 w4 w1 w2 w3 w4 w1 w2 w3 w4 w1 w2 w3 w4 w1 w2 w3 w4 w1 w2 w3 w4 w1 w2 w3 w4 w1 w2 w3 w4 w1 w2 w3 w4 w1 w2 w3 w4 w1 w2 Oct Nov Dec Jan Feb Mar Apr May Jun Juj Aug Sep 10
Regional situation for on-going outbreaks of HPAI in poultry and wild birds (18 September 2017) Region Count of countries affected by ongoing outbreaks Percentage of countries within the Region List of countries List of Strains Aggregated count of poultry destroyed for ongoing outbreaks Africa 8 15% Asia and the Pacific 8 22% Cameroon, Dem. Rep. Congo, Egypt, Niger, Nigeria, South Africa, Togo, Zimbabwe. China, Chinese Taipei, India, Rep. Korea, Laos, Myanmar, Philippines, Vietnam H5N1, H5N8 H5N1, H5N2, H5N6, H5N8, H7N9 1 478 697 29 888 335 Europe 7 13 % France, Germany, Italy, Montenegro, Russian Federation, Slovenia, Switzerland H5N5, H5N8 665 566 Total 23 19% 32 032 598 11
HPAI in Asia (2017) H5N1 China, Laos, Myanmar, Nepal, Bangladesh, Cambodia, India, Malaysia, Vietnam H5N2 Chinese Taipei (since 2015) H5N6 Philippines (Aug 2017), Vietnam (Sept 2017), China, Chinese Taipei, Hong Kong, Japan, R. Korea, Laos, Myanmar, H5N8 - Russia, R. Korea, India, Nepal, China, Chinese Taipei, H7N9 China 12
Distribution of HPAI in Asia, the Far East and Oceania in 2016 and 2017 (Poultry) 01/10/2017 13
Distribution of HPAI in Asia, the Far East and Oceania in 2016 and 2017 (Wild birds) 01/10/2017 14
Percentage of the reporting countries and territories for each semester between 2005 and the first semester of 2017 that notified HPAI No. countries / territories 45 40 35 30 25 20 15 10 5 0 % countries / territories 1st 2nd 1st 2nd 1st 2nd 1st 2nd 1st 2nd 1st 2nd 1st 2nd 1st 2nd 1st 2nd 1st 2nd 1st 2nd 1st 2nd 1st sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. sem. 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 60% 40% 20% 0% Countries and territories reporting HPAI present Countries and territories reporting HPAI absent % reporting countries and territories affected with HPAI 15
HPAI H5N1 situation Asian lineage H5N1 continued to be reported from few countries of Asia and Africa. Virus become enzootic in Asia and Africa and continues to cause outbreaks in poultry and sporadic human infections All cases of H5N1 infection in people have been associated with close contact with infected live or dead birds, or H5N1- contaminated environments Countries affected should focus on strengthening biosecurity measures to prevent introduction of disease into flocks and avoid contact of wild birds with poultry. 16
H7N9 situation Since its origin in 2013, the H7N9 virus remained LPAI in poultry mainly in China but caused over 1562 human infections (as of 13 September 2017). From early 2017, HPAI H7N9 reported from China H7N9 LPAIVs and HPAIVs have spread to multiple provinces in China Seven outbreaks of H7N9 HPAI in poultry in China have been reported during the past four months (May August). 17
HPAI in Africa (2017) In Africa since 2016: 121 Total Outbreaks 78 % of outbreaks in poultry 22 % of outbreaks in wild birds Millions of poultry destroyed H5N1 Cameroon, Cote d Ivoire, Niger, Nigeria, Togo H5N8 - South Africa, Zimbabwe, D.R. Congo, Cameroon, Egypt, Nigeria, Tunisia, Niger, Uganda H7N1(Algeria) 18
HPAI H5N8 outbreaks in 2016/17 Situation in Europe 05/09/2017 In 2016-2017, HPAI H5N8 HPAI spread in Europe. In total, 25 countries in Europe have reported events for H5N8 in 2017 so far. Events are still on-going in 7 of them. In Europe since 19 October 2016: 1939 Total Outbreaks 45% of outbreaks in poultry 55% of outbreaks on wild birds 7,264,284 poultry destroyed 19
Impact of HPAI year wise Year Number of countries affected Number of outbreaks Number of poultry destroyed 2015 40 3,489 29,898,755 2016 51 3,676 16,754,862 2017 66 3,731 29,063,350 20
Conclusion HPAI continue to be a global and regional threat for both public and animal health Every year there is an increase in the number of affected countries and also the circulating subtypes H5N8 subtype was notified by the highest number of countries at global level surpassing H5N1 The OIE encourages its Member Countries to improve surveillance in poultry and wildlife and to continue to timely report all outbreaks information through WAHIS. Timely and accurate information allow deeper epidemiological analysis, and could help the Member Countries to adopt proper biosecurity measures to avoid the spread of the disease between farms and to limit the contact between poultry and wild birds. 21
Thank you for your kind attention! Dr Gounalan Pavade Chargé de Mission g.pavade@oie.int 22