Kupipakwa rasayana. Dr Raghuveer. Dept of Rasashastra KVG Ayurvedic Medical College Sullia

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Kupipakwa rasayana Dr Raghuveer Dept of Rasashastra KVG Ayurvedic Medical College Sullia ayuraghu@rediffmail.com

Rasavaidya shresthata UTTAMO RASAVAIDYASTU MADHYAMO MOOLIKADIBHI: SHASTRASTADHAMAHA.. 2

Chaturvidha rasayana KHARALIYA RASAYANA PARPATI RASAYANA POTTALI RASAYANA KUPIPAKWA RASAYANA 3

KUPI PAKWA RASAYANA ALPAMAATROPAYOGITWAT ARUCHERAPRASANGATAH KSHIPRAMAAROGYADAAYITWAT OUSHADHEBHYO ADHIKO RASA 4

HISTORY 12 th century AD onwards Sri Dundukanatha Rasendra chintamani Best example of Murchana Agni- Kramaagni Valuka Yantra 5

Contd Ancient Indian alchemists were expert in transforming lower metals to higher metals. In this way ancient scholars were used to potentiate and transform mercury to certain higher level metals by different Jarana procedures. In Jarana process, Gandhaka was commonly used for this purpose. Different proportion of Gandhaka was used to mix with Parada and gradually potentiate the preparation of Parada. In such experimentation of Jarana, the use of Kupipakva method was adopted. It is believed that the cause for the invention of Kupipakva method might be certain special procedures done on Parada and Gandhaka and also the temperature is particularly controlled to get the desired effect in the final product. Such procedures of Gandhaka Jarana have firstly been mentioned by Acharya Govinda Bhagvat Pada in his treatise. In 8th century A.D. Govinda Bhagavatpada described Gandhaka Jarana vidhi in Rasa Hridaya Tantra. Sri Dundukanatha, the author of Rasendra Chintamani was the first person to introduce preparations in the Ayurvedic therapeutics during 12th century A.D. 6

Contd In Rasendra Chintamani there is clear cut reference about specific heating pattern named as Kramagni paka i.e. increasing manner of heat (Mrudu, Madhya and Tivragni), with intermediate heating for a specific period has been mentioned. The same method is used in practice now a days with some modifications. Kupipakva Rasayana was developed by Siddha Sampradaya i.e. from 13 th century. Acharya Yoshodhara Bhat (13 th cent.) in his text Rasa Prakash Sudhakar quoted Sindhura Kalpana by the name of Udayabhaskar Rasa. Udaya Bhaskara rasa is nothing but the name of Rasasindura. At the same place, he has given the method of Rasakarpura preparation by the name "Ghanasara-Rasa". He has used Kachaghati (Kupi) Sikatayantra for the preparation of Udayabhaskar Rasa (Rasa Prakash Sudhakar 3/10-14). 7

Contd In Anandakanda, Manthana Bhairava writes about the same procedure under the heading of Rasa Murcchana vidhi. In 13 th century A.D, Rasa Vagbhata, the author of Rasa Ratna Samucchaya mentioned some preparations by combining Parada with Gandhaka such as Agnikumara Rasa. The classics of 15 th, 16 th, 17 th century explained in the name of Sindhura Rasa or Sindhura Sadrisha Rasa. In 15th century, Anantdev Suri in his text Rasa Chintamani described Rasaparthiva Rasa". Overall after critical study, one can come to conclusion that process of Gandhaka Jarana mentioned in Rasa Hridaya Tantra, developed and came inlight as Kupipakva Rasayana. Kupi Pakva Rasayana Kalpana is also known as Sindhura Kalpana. 8

Derivation KUPI ITI KACHA KUPI PAKWAM ITI AGNINA PAKWAM RASASYA PARADASYA AYANAM STHANAM ARTHAT KUPYAM AGNINAM PAKWAM YADRASAAYANAM TAT KUPI PAKWA RASAYANAM 9

SPECIFIC FEATURES Specialized heating pattern Valuka yantra Indirect constant heat Dose 10

Classification 256 kupi pakwa rasayanas mentioned by Sri Harisharanananda in his grantha kupi-pakwa vijnaniyam Classified as follows- Mercury + sulphur Mercury + sulphur + metals Mercury + sulphur + non-metals Mercury + sulphur + metals + non-metals Mercury + other compounds 11

Ingredients Sagandha Prepared with the use of Gandhaka e.g. Vyadhiharana Rasa Makaradhwaja, ManikyaRasa, Rasa sindhura. Nirgandha Prepared without the use of Gandhak e.g. Rasakarpura, Rasa Pushpa Manufacturing method Antardhuma is applied in the beginning and the vapors are not allowed to escape e.g. Rasasindhura. Bahirdhuma is applied after burning of sulphur e.g. Vyadhiharana Rasa, Hinguliya Manikya Rasa, Sila sindhura. Place of finished product Kanthastha Talastha The finished product is deposited at the neck e.g. Makaradhwaja, Rasa sindhura The product is obtained from the bottom of the Kupi e.g. Sameerapannaga-Rasa, Swarna Vanga. Ubhayastha Final products obtained from both the sites e.g. Sameerapannaga Rasa, Hinguliya Manikya Rasa. 12

Kanthastha/galastha Talastha Ubhayastha 13

Method 1 Poorva karma 2 Pradhana karma 3 Paschat karma 14

Poorva karma 15

Collection of necessary instruments Shodhana Kajjali Preparation of kupi Filling of kajjali to kupi Placing kupi in valuka yantra 16

Collection of necessary instruments Musha / kupi Vastra (cotton cloth) Multani mrittika Valuka yantra/emf Valuka Shalaka Copper coin 17

Shodhana Raw materials identified first and then subjected to shodhana as per the ref. Samyak shuddhi lakshanas obseved 18

Preparation of Kajjali Slakshnatwa Kajjalabhasa Nishchandratwa 19

Preparation of Kupi Selection of bottle Wrapping glass bottle with mud smeared cloth As per classic 7 layers 20

Filling of kajjali to kupi Fill 1/3 rd part so that there should be free space inside kupi for melting and boiling of kajjali Also for sublimation of compound which is going to condensed and deposited in neck part 21

Placing kupi Placed at the centre part of the valuka yantra so that to get uniform temperature 22

Pradhana karma 23

Heating schedule Temperature recording Shalaka sanchalana Observation of fumes and flame Corking of kupi mouth Swangasheeta 24

BMK Ayurveda Mahavidyalaya Belgaum 25

26

Valuka yantra 27

Baidyanath Pharma Alahabad 28

Ipgtra jamnagar 29

EMF (Electric Muffle Furnace) 30

Kramagni Heating schedule Mrudu agni Madhyama agni Teevra agni 31

Temperature Ancient method- cotton/dried husk test Modern method: Thermometer/Pyrometer/Thermocouple 32

Shalaka sanchalana Tapta shalaka- to burn extra sulphur deposited as neck part of kupi Sheeta shalaka- to know the state of kajjali i.e. powder form / melted / boiling / sublimation stage of product 33

Shalaka sanchalana 34

Observation of fumes and flame Fumes colour, odour, Differs acc to ingredients Yellow / orrange / bluish / white Odour like sulphur / arsenic Flames timing of appearance of flame, its colour and duration noted 35

Observation of fumes/flames 36

Corking of kupi Before corking Observe for- Absence of fumes and flames Copper coin test Sheeta shalaka test Appearance of redness at the bottom of kupi Adherence of golden particles 37

Copper coin test 38

Paschat karma 39

Removal of kupi from valuka yantra Breaking of kupi Collection of product Examination of product 40

Removal of kupi Care should be taken sometimes kupi may break 41

Breaking of kupi Traditional method Scrap and remove the layers of kupi A thread soaked in spirit should be tied around the middle of kupi and ignited Kept horizontally, rotate the kupi to burn thread Then wrap with wet cloth 42

Breaking of Kupi 43

Collection of product Kanthasta / Talastha/ Ubhayastha Rasasindhur, Malla sindhur kanthastha Swarna vanga talasta Makaradhwaja, hinguliya manikya rasa- Ubhayastha 44

Collection of Swarna vanga (Talastha) 45

Collection of Kanthasta material 46

Examination of product Physical / organoleptic examination: Colour, odour, consistancy, shiny, soft, crystalline, amorphous etc Chemical examination: Qualitative / Quantitative Instrumental examination: XRD/XRF/IR/UV/ ICPMS/ TEM/ AAS/flame photomter etc 47

IMPORTANCE OF KUPIPAKWA RASAYANA Kupipakva Rasayana Kalpana is having importance among other Kalpanas because of having following properties: (1) Potency of these drugs remains for longer period. (2) It requires minimal dose. (3) Easy for administration. (4) More potent as compared to other pure herbal preparations. (5) When mixed with other drugs, it reduces the dose of other drugs. (6) Due to its quicker action. (7) Chemical bond becomes stronger in the following order; Kajjali, Parpati, Pottali and Kupipakva Rasayana. 48

SIDDHE RASE KARISHYAMI NIRDARIDYAMAYAM JAGAT 49