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New Advancements in Clinical and Molecular Research in Sleep Medicine, FAAFP Professor and Chair Family Medicine Community Health, M.B.B.S. Director American Board of Sleep Medicine Sleep Medicine Specialist Mayo Clinic, Ph.D., FAASM Professor of Psychiatry and Behavioral Science Division Chief and Director Stanford Sleep Medicine Stanford University Associate Professor Clinical Medicine Sleep Medicine Specialist UHealth Pulmonary and Sleep Medicine Presented by: Sponsored by: bm.med.miami.edu bmbinfo@miami.edu (305) 243-3710

Overview According to the National Commission on Sleep Disorders Research, 37% of medical schools have reported they do not have any structured teaching time to address Sleep Disorders. In addition, 90% of students are not trained in the use of sleep laboratory procedures and 89% have not participated in the clinical evaluations of patients with sleep disorders. This CME, New Advancements in Clinical and Molecular Research in Sleep Medicine, will provide in-depth knowledge in diagnosing and treating the link between diseases such as, CHF and Arrhythmia and Sleep Apnea. Attendees will participate in clinical sessions where they will learn about best case management, identification of clinical cases, and case-specific billing processes. Cardiovascular diseases, neurological disorders, respiratory disorders, allergies, pediatric metabolic disorders, physician burn out, shift work disorders and their effect on sleep physiology is not well recognized. In order to close these healthcare gaps and improve diagnosis and treatment, a new and integrative approach is needed. Often, a patient seeking help from a sleep laboratory is one who has already seen a doctor and has not found a successful treatment for their ailment. These individuals have a history of low job performance and job-related accidents. Therefore, with proper training, practitioners will be able to effectively, diagnose, monitor and treat patients decreasing work place accidents. During this CME, there will be discussions about different surgical approaches to obstructive sleep disorder management. After completing this CME, physicians will be able to properly diagnose and treat patients with a Sleep Disorder.

Learning Objectives & Accreditation Learning Objectives At the end of the activity the learners will be able to: Recognize signs and symptoms of common sleep disorders. Identify various therapeutic applications for sleep disorders. Acquire documentation and hands-on skills applicable to clinical settings in recognition and treatment of sleep related disorders. Identify various clinical cases in residency settings to enhance understand of sleep disorders. Identify complications in clinical medicine patients who have respiratory disease or cardiovascular disease associated with sleep disorders. Identify the psychiatric components of clinical presentation of patients suffering from sleep disorders. Acquire practical knowledge of diagnostic tests and interpretation of sleep related disorders. Recognize the origin of sleep pathologies related to work environments and professional burnout due to lack of sleep. ACCREDITATION, Leonard M. is accredited by the ACCME to provide continuing medical education for physicians. CREDIT DESIGNATION Leonard M. designates this live activity for a maximum of 18 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

AGENDA Every lecture will conclude with a Q&A with the audience. Nov 15 4:00 PM Arrival & Registration 6:00 PM Welcome Reception Nov 16 7:00-8:00 AM Continental Breakfast 8:00-9:00 AM Keynote Speaker Professor E. Robert Schwartz,, FAAFP Chair, Department of Family Medicine & Community Health,, 9:00-10:00 AM Clinical Advances in Sleep Medicine Alejandro D. Chediak, 10:00-10:15 AM Break 10:15-11:15 AM Clinical Recognition and Management of Common Sleep Disorders Alberto Ramos,, MSPH, FAASM 11:15-12:15 PM Therapeutic Approach for Clinical Sleep Disorders Mohammad Newaz,, Ph.D., FAHA. 12:15-1:15 PM Lunch 1:15-2:15 PM Novel Markers in Sleep Physiology (Cardiorespiratory Coupling, Heart Rate Variability, Augmentation Index) Marcos A. Sanchez,, Ph.D. 2:15-3:15 PM Surgical Approaches of Sleep Disorders Ricardo M. Ortiz,, D. 3:15-3:30 PM Break 3:30-4:30 PM Complications and Management of Sleep-Related Disorders in Patients with Respiratory Disorders Alexandre R. Abreu,

AGENDA Every lecture will conclude with a Q&A with the audience. Nov 17 7:30-9:00 AM 9:00-10:00 AM Continental Breakfast Sleep Study Reports and it's Interpretation Mujibur R. Majumder,, M.P.H., F.C.C.P. 10:00-11:00 AM Future Perspectives in Sleep Medicine Research Clete A. Kushida,, Ph.D., FAASM 11:00-11:15 AM Break 11:15-12:15 PM Complications and Management of Sleep-Related Disorders in Patients with Psychiatric Disorders Gerardo F. Ferrer, 12:15-1:15 PM 1:15-2:15 PM 2:15-3:15 PM 3:15-3:30 PM 3:30-5:30 PM Lunch Diagnostic Workup of Sleep Disorders in Children Lourdes Delrosso, MSEd. Complications and Management of Sleep-Related Disorders in Patients with Cardiac Disorders Kannan Ramar,, M.B.B.S. Break Panel Discussion: Clinical Case Presentation on Sleep- Related Disorders Jasmin Ahmed, Panel Members: Syed Rizvi, Ph. D., Gerardo Ferrer,, Marcos Sanchez,, Sultan S. Ahmed, Nov 18 7:30-9:00 AM 9:00-10:00 AM Continental Breakfast Shift Work Disorder, Work Burnout, and Sleep Quality Ross W. May, Ph.D. 10:00-11:00 AM Sleep-Related Disorders: A Primary Care Perspective José David Suarez, 11:00-11:15 AM Break

AGENDA Every lecture will conclude with a Q&A with the audience. Nov 18 11:15-1:15 PM 1:15-2:15 PM Panel Discussion: Hands-on session: Guidelines on Best Practices and Documentation for Billing and Coding in Sleep Disorders Justin Singh, Panel Members: Sultan S. Ahmed,, Mujibur Majumder,, Marcos Sanchez, Closing Remarks

CME EVENT ORGANIZERS Sylvia Daunert Pharm.D., M.S., Ph.D. Professor and Lucille P. Chair Biochemistry and Molecular Biology Sultan S. Ahmed Clinical Voluntary Professor CME Director Biochemistry and Molecular Biology Zafar Nawaz Ph.D. Professor and Senior Associate Dean CME Co-Director Biochemistry and Molecular Biology MILLER SCHOOL OF MEDICINE FACULTY Alejandro D. Chediak Associate Professor Clinical Medicine E. Robert Schwartz, FAAFP Professor and Chair Family Medicine Community Health Alexandre R. Abreu Associate Professor of Medicine Director UHealth Sleep Center Alberto Ramos, MSPH, FAASM Associate Professor of Clinical Neurology Research Director UHealth Sleep Medicine Program

GUEST FACULTY Clete A. Kushida, Ph.D., FAASM Professor of Psychiatry and Behavioral Science Division Chief and Director Stanford Sleep Medicine Stanford University Lourdes DelRosso, MEd, FAASM Associate Professor of Pediatrics Sleep Physician Seattle Children s Hospital University of Washington Kannan Ramar, M.B.B.S. Director American Academy of Sleep Medicine Sleep Medicine Specialist Mayo Clinic Mohammad Newaz, Ph.D., FAHA Professor and Chair Pharmaceutical Sciences College of Pharmacy Chicago State University Marcos A. Sanchez-Gonzalez, Ph.D. Adjunct Professor of Clinical Medicine Lake Erie College of Osteopathic Medicine Vice President for Research and Academic Affairs Larkin Hospital José David Suarez Voluntary Assistant Clinical Professor Herbert Wertheim College of Medicine Florida International University Diplomate of the American Board of Family Medicine Seneca District Hospital Ross W. May Ph.D. Assistant Professor & Associate Director of Research Family Institute Florida State University

Gerardo F. Ferrer Assistant Clinical Professor of Psychiatry Lake Erie College of Osteopathic Medicine Chair Department of Psychiatry Larkin Hospital Ricardo M. Ortiz, D. Oral and Maxillofacial Surgeon Massachusetts General Hospital PANELISTS Mujibur R. Majumder, M.P.H., F.C.C.P. Associate Professor of Clinical Medicine Director Pulmonary Critical Care and Sleep Medicine Medical Center Brooklyn Brookdale University Hospital Syed A. Rizvi Ph.D., M.S., M.B.A. Associate Professor of Pharmacy College of Pharmacy Nova Southeastern University Justin Singh Psychiatric Department Larkin Hospital REGISTRATION Jasmin Ahmed Psychiatric Department Larkin Hospital REGISTER NOW! Please visit http://bit.ly/bmbcme to Register Online and process the Registration fee. Before 09/15/2018 $550 $400 $75 After 09/15/2018 $650, Ph.D. and D.O $450 Physician Assistants and Nurse Practitioners $75 Residents and Fellows REGISTRATION CANCELLATION POLICY Refunds will be made only if written notice of cancellation is received prior to October 15th, 2018. A 20% fee will be charged for all refunds. In cases where a course is cancelled due to insufficient registrations, a full tuition refund will be made.

HOTEL & TRAVELING Diplomat Resort & Spa 3555 S Ocean Dr. Hollywood, FL 33019 954-602-6000 HOTEL, CME PARTICIPANT RATE A block of rooms has been reserved for conference participants at a discounted rate of US$239/night + tax for a guest room. All individual reservations must be accompanied by a first night room deposit or guaranteed with a major credit card. The hotel will not hold any reservations unless secured by one of the above methods. Driving Directions: www.bit.ly/cmedirections LOCAL HIGHTLIGHTS Hollywood, FL Seminole Hard Rock Casino Hollywood Beach Anne Kolb Nature Center West Lake Park ArtsPark at Young Circle Miami, FL Wynwood PAMM Frost Museum Miami Seaquarium Jungle Island Historic Virginia Key Park Everglades Tour by Airboat (305) 754-2206 Miami City Tour (800) 3031503

DISCLOSURE AND CONFLICT OF INTEREST RESOLUTION All conflicts of interest of any individual(s) in a position to control the content of this CME activity will be identified and resolved prior to this educational activity being provided. Disclosure about provider and faculty relationships, or the lack thereof, will be provided to the learners. In accordance with the 2004 Updated ACCME Standards for Commercial Support the University of Miami Leonard M. requires everyone in a position to control the content of a continuing medical education activity Course Director(s), Planning Committee Members and all individuals participating as speakers, moderators or authors to disclose all relevant financial relationships with commercial interests. All potential conflicts are identified and resolved prior to the educational activity being provided to learners. Disclosure of relevant financial relationship(s) will be provided to learners prior to the beginning of the educational activity. SERVICES FOR THE DISABLED If special arrangements are required for an individual with a disability to attend this conference, contact Sebastian Rodriguez at (305) 243-3710 at least 15 days prior to the conference. For More Information Contact: Sebastian Rodriguez at (305) 243-3710 or bminfo@miami.edu