SAVE THE DATE FOR THE 2019 AIRR COMMUNITY MEETING. Bridging the Gaps MAY 2019, Genoa, Italy

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SAVE THE DATE FOR THE 2019 AIRR COMMUNITY MEETING Bridging the Gaps 11-15 MAY 2019, Genoa, Italy Dear AIRR Community Members and other Members of The An body Society, We are pleased to announce the 4th AIRR Community Mee ng to be held May 11-15, 2019 at the University of Genoa Scuola Politecnica, Italy. Dr. Davide Bagnara from the University of Genoa has very kindly organized this excep onal mee ng site. The dra agenda (see below) was developed with input from the AIRR Execu ve Commi ee and Working Groups (WGs). We have designed a schedule to provide ample me for WGs discussions and presenta on of the latest scien fic findings. The theme of this mee ng, Bridging the Gaps addresses technological gaps between the amounts of accumulated data and our ability to process them, and the need for more involvement of stakeholder communi es (industry, clinicians, pa ent communi es) for uptake of the standards developed by the AIRR Community. We have confirmed two outstanding Keynote speakers Dr. Sai Reddy from ETH Zurich and Dr. Antonio Lanzavecchia from IRB Bellinzona. Two planned panel discussions will include representa ves from other ins tu ons and companies that work with AIRR-seq data. In addi on, two challenge sessions are planned to address the above-men oned gaps. Two pre-mee ng workshops will be available to teach the basics of immunology, and of AIRR-seq data analysis for beginners. Also planned are two poster sessions; and two tool and so ware demos sessions. We now invite you to submit your sugges ons for addi onal speakers in the Scien fic Sessions; please send them to us no later than December 1 st, 2018. Following our last mee ng in December 2017, the AIRR Community has joined the An body Society (TAbS). TAbS is a sponsor of the mee ng, along with the University of Genoa, and we are currently seeking other sponsors. Please send Ramit Mehr or Jamie Sco sugges ons for poten al sponsors and their contact informa on! Finally, you can review the videos from the 2017 third annual AIRR Community Mee ng! Please find them at h ps://www.an bodysociety.org/airr-community-mee ng-iii/

We re looking forward to your sugges ons, and to another outstanding AIRR Community Mee ng! Registra on will be available early this fall. Stay tuned for an update! The AIRR Community Mee ngs Subcommi ee, Prof. Jamie Sco Simon Fraser University, Canada Email: jksco @sfu.ca Prof. Ramit Mehr Bar-Ilan University, Israel Email: ramit.mehr@biu.ac.il Dr. Davide Bagnara University of Genoa, Italy Email: davide.bagnara@edu.unige.it Dr. Jean-Philippe Bürckert BISC Global, USA Email: jean.buerckert@biscglobal.com Encl.: Mee ng Program at a Glance Mee ng Agenda

Meeting Program at a glance: AIRR-Community Meeting IV Preliminary Agenda 11-15 May 2019 Genoa, Italy Saturday, May 11 : WG Mee ngs, Workshops and WG Progress Reports 8:30 9:00 Coffee & snack provided 9:00 14:00 WGs meet separately (Each WG will provide a separate agenda to its members) 9:00 12:00 Workshop I - Fundamentals of the Immune System 9:00 12:00 Workshop II - AIRR-Seq Data Processing and Analysis (including AIRR-C standards for data and storage) 10:30 11:00 Coffee Break 12:00 13:00 Lunch (provided)

14:00 14:30 Biobreak 14:30 14:40 Welcome by current Chair and Chair-elect of the AIRR-C Committee of TAbS Introduction to Working Group Reports on Progress, Future Plans & Leadership 14:40 15:10 Software WG Report 15:10 15:40 Data Representation WG Report 15:40 16:10 Germline DB WG Report 16:10 17:00 Panel Discussion: Data Representation and Germline Databases WGs Dinner on your own Sunday, May 12 : WG and Communica on Subcommi ee Progress Reports 8:30 9:00 Coffee & snack provided 9:00 9:10 Introduction to Day 2 of Progress Reports 9:10 9:40 Biological Reagents WG Report 9:40 10:10 Minimal Standards WG Report 10:10 10:40 Common Repository WG Report 10:40 11:30 Panel Discussion: Common Repositories, Software and Minimal Standards WGs 11:30 14:00 Lunch (on your own) 14:00 14:30 Introduction to the Communications Subcommittee & Report 14:30 15:00 Discussion on Communica on Subcommi ee s Proposed Plan 15:00 17:00 AIRR-C Meeting Welcome Reception Dinner on your own Monday, May 13 : Scien fic Progress & Challenges (Basic Science) 8:00 8:30 Coffee available at the Meeting Site 8:30 8:50 Introduction to the Meeting and Keynote 8:50 9:40 Keynote: Sai Reddy 9:40 13:05 Scientific Session: Advances in Characterization of Immune Responses by AIRR-Seq Data 13:05 15:00 Lunch Break + Poster Session 15:00 17:00 Challenge Session: Processing and Storing Massive AIRR-Seq Data (>1bn Sequences) 17:00 19:30 AIRR-Seq Tools Demos and Reception Tuesday, May 14 : Scien fic Progress & Challenges (Clinical Science and Transla on) 8:00 8:40 Coffee available at the Meeting Site 8:40 8:50 Introduction to the Keynote 8:50 9:40 Keynote: Antonio Lanzavecchia 9:40 13:05 Scientific Session: Advances in AIRR-seq Addressing Human Health and Disease 13:05 15:00 Lunch Break + Poster Session 15:00 15:10 Challenge Session: Engaging Stakeholders in Research and Translation 15:10 16:40 Subsession: Patient & Community Engagement 16:40 17:30 Subsession: Engaging Industry 17:30 18:30 Recep on with Session Speakers 19:30 22:00 Group Dinner (requires separate registration!)

Wednesday, May 15: AIRR-C Organisa onal Session 8:30 9:00 Coffee available at Meeting Site 9:00 9:10 Introduction to the AGM of the AIRR-Community Members 9:10 11:10 WG work plans & leadership 11:10 11:30 Coffee Break 11:30 11:30 AIRR-C Standing Committee plans and voting 11:30 11:50 Execu ve Subcommi ee 11:50 12:10 Mee ng Subcommi ee 12:10 12:30 Communica ons Subcommi ee 12:30 14:30 Meeting adjourned & Lunch on your own 14:30 17:30 Standing Subcommi ees & WG wrap-up mee ngs