WESTERN BLOTS & LINE IMMUNO ASSAYS

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1 1 WESTERN BLOTS & LINE IMMUNO ASSAYS FEBRUARY 2010 AUTOIMMUNE DISEASE NEW! DT-ANA8D-24 BlueDot ANA 8 Sm; Sm/RNP; SSA(Ro); SSB(La); Jo-1; Scl-70; PM-Scl; CENP-A/B NEW! DT-ANA10D-24 BlueDot ANA 10 Sm; Sm/RNP; SSA(Ro); SSB(La); Jo-1; Scl-70; PM-Scl; Ku; CENP-A/B; PCNA NEW! DT-ANA12D-24 BlueDot ANA 12 Sm; RNP (68kD/A/C); Sm/RNP; SSA(Ro); SSB(La); Jo-1; Scl-70; PM-Scl; Ku; CENP-A/B; PCNA; Ribosome P(P0) NEW! DT-ANA12SD-24 BlueDot ANA 12 IgG Screen Sm; RNP (68kD/A/C); Sm/RNP; SSA(Ro); SSB(La); Jo-1; Scl-70; PM-Scl; Ku; CENP-A/B; PCNA; Mi-2 MG-6072 recomline ANA/ENA IgG RNP68, RNPA, RNPC, SmB, SmD, Ro/SSA60, Ro/SSA52, La/SSB, hy-rnp, Rib-P, PCNA, CENPB, Scl-70, Jo-1 rlia 25 tests NEW! DT-ANCAD-24 BlueDot ANCA2 IgG MPO, PR2 NEW! DT-ANCAGD-24 BlueDot ANCA + GBM IgG MPO; PR3; GBM (Goodpasture antigen) NEW! DT-APSGD-24 BlueDot APS IgG Cardiolipin/B2-Glycoprotein I complex; B2- Glycoprotein I isolated protein NEW! DT-ENDA-24 BlueDot Celiac IgA deamidated Gliadin; tissue Transglutaminase NEW! DT-ENDG-24 BlueDot Celiac IgG Gliadin; tissue Transglutaminase NEW! DT-CHRD-24 BlueDot Chromatin IgG Nucleosome; dsdna; Histones NEW! DT-CTD-24 BlueDot Connectivitis IgG NEW! DT-CT10D-24 BlueDot Connectivitis 10 IgG NEW! DT-CY6D-24 BlueDot Cytoplasm6 IgG Nucleosome; Histones (total); Sm; Sm/RNP; SSA(Ro); SSB(La); Jo-1; Scl-70 Nucleosome; dsdna; Histones (total); Sm; Sm/ RNP; SSA; TRIM21; SSB; Jo-1; Scl-70 M2 (PDH,OGDC,BCOADC); Jo-1; PL-7; PL-12; SRP; Ribosome P(P0) NEW! DT-DNAD-24 BlueDot dsdna IgG dsdna NEW! DT-ENAD-24 BlueDot ENA6 IgG Sm; Sm/RNP; SSA(Ro); SSB(La); Jo-1; Scl-70 NEW! DT-NUENAD-24 BlueDot ENA + Nucleosome IgG Nucleosome; Sm; Sm/RNP; SSA(Ro); SSB(La); Jo-1; Scl-70

2 2 AUTOIMMUNE DISEASE - Kits; continued NEW! DT-IFPCAD-24 BlueDot Gastritis IgG Intrinsic Factor; Parietal cell antigen (H+/K+ ATPase) NEW! DT-GBD-24 BlueDot GBM IgG GBM (Goodpasture antigen) NEW! DT-IFD-24 BlueDot Intrinsic Factor IgG Intrinsic Factor NEW! DT-LID-24 BlueDot Liver3 IgG M2 (PDH,OGDC,BCOADC); LKM1 (P450 2D6); LC1 (Formiminotransferase cyclodeaminase) NEW! DT-LISD-24 BlueDot Liver5 IgG F-actin; M2 (PDH,OGDC,BCOADC); LKM1; LC1; SLA (Soluble Liver Antigen) NEW! DT-LI7D-24 BlueDot Liver7 IgG M2; gp210; sp100; LKM1; LC1; SLA; F-actin NEW! DT-LUD-24 BlueDot Lupus IgG Nucleosome; Histones (total); Sm; Ribosome P (P0) NEW! DT-LU6D-24 BlueDot Lupus 6 IgG Nucleosome; dsdna; Histones; Sm; Ribosomes; Cardiolipin/B2-Glycoprotein I complex NEW! DT-MID-24 BlueDot M2 IgG/IgM M2 (Mixture of PDH,OGDC and BCOADC) NEW! DT-MI3D-24 BlueDot M3 IgG/IgM Separated M2 antigens OGDC-E2; BCOADC-E2; PDH-E2 NEW! DT-NUD-24 BlueDot Nucleosome IgG Nucleosome NEW! DT-NUHISD-24 BlueDot Nucleosome/Histones IgG Nucleosome; Histones (total) NEW! DT-PMS8D-24 BlueDot Polymyositis/Scleroderma8 IgG Jo-1; PL-7; PL-12; SRP; Mi-2; Ku; PM-Scl; Scl-70 MG-6372 recomline Scleroderma Scl-70, PMScl100, Scl34 (U3-RNP), CENPB rlia 25 tests NEW! DT-TTAD-24 BlueDot Transglutaminase IgA tissue Transglutaminase NEW! DT-TTGD-24 BlueDot Transglutaminase IgG tissue Transglutaminase GASTROENTEROLOGY NEW! DT-ASCCD-24 BlueDot ASCA IgG/IgA Saccharomyces cerevisiae (mannan) NEW! DT-ENDA-24 BlueDot Celiac IgA deamidated Gliadin; tissue Transglutaminase NEW! DT-ENDG-24 BlueDot Celiac IgG Gliadin; tissue Transglutaminase NEW! DT-IFPCAD-24 BlueDot Gastritis IgG Intrinsic Factor; Parietal cell antigen (H+/K+ ATPase) NEW! DT-IFD-24 BlueDot Intrinsic Factor IgG Intrinsic Factor NEW! DT-BSD-24 BlueDot Milk Intolerance IgG Beta-Lactoglobulin (cow\ s milk); Soya (purified soya proteins)

3 3 INFECTIOUS DISEASE BACTERIA MG-5773 Bordetella pertussis IgA recomline Bordetella pertussis rlia 20 tests MG-5772 Bordetella pertussis IgG recomline Bordetella pertussis rlia 20 tests VT-WE115A32 Bordetella pertussis Line IgA Bordetella pertussis LIA VT-WE115G32 Bordetella pertussis Line IgG Bordetella pertussis LIA MG-4202NB Borrelia NB IgG recomblot B. burgdorferi s.s, B. afzelii, B. garinii rwbl 20 tests MG-4203NB Borrelia NB IgM recomblot B. burgdorferi s.s, B. afzelii, B. garinii rwbl 20 tests MG-4272 Borrelia IgG recomline B. burgdorferi s.s, B. afzelii, B. garinii, B. spielmanii rlia 20 tests MG-4276 Borrelia IgG recomline B. burgdorferi s.s, B. afzelii, B. garinii, B. spielmanii rlia 200 tests MG-4273 Borrelia IgM recomline B. burgdorferi s.s, B. afzelii, B. garinii, B. spielmanii rlia 20 tests MG-4277 Borrelia IgM recomline B. burgdorferi s.s, B. afzelii, B. garinii, B. spielmanii rlia 200 tests MG-4212 Borrelia canis IgG recomblot B. burgdorferi s.s, B. afzelii, B. garinii rwbl 20 tests MG-4213 Borrelia canis IgM recomblot B. burgdorferi s.s, B. afzelii, B. garinii rwbl 20 tests VT-WE023G30 VT-WE023G90 Borrelia afzelii + VlsE EcoBlot IgG B. afzelii WBL 30 tests 90 tests VT-WE022M30 VT-WE022M90 Borrelia afzelii EcoBlot IgM B. afzelii WBL 30 tests 90 tests VT-WE222G16 VT-WE222G32 VT-WE222G96 Borrelia Line IgG B. burgdorferi s.s, B. afzelii, B. garinii LIA 16 tests VT-WE222M16 VT-WE222M32 VT-WE222M96 Borrelia Line IgM B. burgdorferi s.s, B. afzelii, B. garinii LIA 16 tests VT-WE224G32 VT-WE224G96 Borrelia EUROPE Line IgG B. burgdorferi s.s, B. afzelii, B. garinii, B. spielmanii LIA VT-WE224M32 VT-WE224M96 Borrelia EUROPE Line IgM B. burgdorferi s.s, B. afzelii, B. garinii, B. spielmanii LIA NEW! NEW! VT-WE225G32 VT-WE225G96 Borrelia EUROPE plus TpN17 Line IgG B. burgdorferi s.s, B. afzelii, B. garinii, B. spielmanii LIA MG-6273 Campylobacter IgA recomline Campylobacter spp. rlia 20 tests MG-6272 Campylobacter IgG recomline Campylobacter spp. rlia 20 tests MG-6173 Chlamydia IgA recomline Chlamydia spp. rlia 20 tests MG-6172 Chlamydia IgG recomline Chlamydia spp. rlia 20 tests MG-4703 Helicobacter IgA ImmunoBlot Helicobacter pylori WBL 20 tests MG-4702 Helicobacter IgG ImmunoBlot Helicobacter pylori WBL 20 tests VT-WE243A32 VT-WE243A96 VT-WE243G32 VT-WE243G96 Helicobacter pylori Line IgA Helicobacter pylori LIA Helicobacter pylori Line IgG Helicobacter pylori LIA NEW! SF-TS2110 Shigatoxin- (Verotoxin) Colony-Immunoblot E. coli CIB 5 tests MG-5102 Treponema IgG recomblot Treponema pallidum rwbl 20 tests

4 4 INFECTIOUS DISEASE - Bacteria - Kits; continued MG-5103 Treponema IgM recomblot Treponema pallidum rwbl 20 tests VT-WE150G16 VT-WE150G32 VT-WE150M16 VT-WE150M32 Treponema pallidum Line IgG Treponema pallidum LIA Treponema pallidum Line IgM Treponema pallidum LIA 16 tests 16 tests MG-4672 Yersinia IgG recomline Yersinia enterocolitica rlia 20 tests MG-4673 Yersinia IgA/IgM recomline Yersinia enterocolitica rlia 20 tests VT-WE242A32 VT-WE242A96 VT-WE242G32 VT-WE242G96 Yersinia enterocolitica LINE IgA Yersinia enterocolitica rlia Yersinia enterocolitica LINE IgG Yersinia enterocolitica rlia VT-WE242M32 Yersinia enterocolitica LINE IgM Yersinia enterocolitica rlia PARASITES MG-5971 Toxoplasma IgA recomline Toxoplasma gondii rlia 20 tests MG-5972 Toxoplasma IgG (Avidity) recomline Toxoplasma gondii rlia 20 tests MG-5973 Toxoplasma IgM recomline Toxoplasma gondii rlia 20 tests VIRUSES MG-4872 Bunyavirus IgG/IgM recomline Hantavirus/Sandfly Fever Virus rlia 20 tests MG-5502 CMV IgG recomblot Cytomegalovirus rwbl 20 tests MG-5503 CMV IgM recomblot Cytomegalovirus rwbl 20 tests MG-4572 EBV IgG (Avidity) recomline Epstein Barr Virus rlia 20 tests MG-4573 EBV IgM/IgA recomline Epstein Barr Virus rlia 20 tests VT-WE102G32 VT-WE102G96 VT-WE102M32 VT-WE102M96 EBV Line IgG Epstein Barr Virus LIA EBV Line IgM Epstein Barr Virus LIA MG-4302 HCV IgG 2.0 recomblot Hepatitis C Virus rwbl 20 tests NEW! MG-5072 HEV IgG recomline Hepatitis E Virus rlia 20 tests NEW! FO-IB900G HerpeSelect 1/2 Immunoblot Herpes Simplex Virus WBL MG-5372 HSV-1 & HSV-2 IgG recomline Herpes Simplex Virus LIA 20 tests VT-WE130G16 VT-WE130G32 HSV Line IgG Herpes Simplex Virus LIA 16 tests MG-4402 Parvovirus B19 IgG/IgM recomblot Parvovirus B19 rwbl 20 tests MG-4472 Parvovirus B19 IgG (Avidity) recomline Parvovirus B19 rlia 20 tests MG-4473 Parvovirus B19 IgM recomline Parvovirus B19 rlia 20 tests MG-4902 Rubella IgG recomblot Rubella rwbl 20 tests Abbreviations: Immuno-Dot-Blot LIA Line Immuno Assay rlia Line Immuno Assay with recombinant Antigens WBL Western Blot rwbl Western Blot with recombinant Antigens

5 5 CONTROLS MG ANA/ENA IgG positive serum 200 µl MG ANA/ENA IgG negative serum 200 µl VT-WE115C60 Bordetella pertussis IgG cut off control (concentrated) 500 µl VT-WE115C40 Bordetella pertussis IgA cut off control (concentrated) 500 µl MG Borrelia IgG positive serum 200 µl MG Borrelia IgM positive serum 200 µl MG Borrelia IgG/IgM negative serum 200 µl VT-WE224C60 Borrelia EUROPE Line IgG cut off control 500 µl VT-WE224C80 Borrelia EUROPE Line IgM cut off control 500 µl NEW! VT-WE225C60 Borrelia EUROPE plus TpN17 Line IgG cut off control 500 µl VT-WE023C60 Borrelia afzelii + VlsE IgG cut off control (concentrated) 500 µl VT-WE023P60 Borrelia afzelii + VlsE IgG positive control (concentrated) 500 µl VT-WE022C80 Borrelia afzelii IgM cut off control (concentrated) 500 µl VT-WE022P80 Borrelia afzelii IgM positive control (concentrated) 500 µl VT-WE222C60 Borrelia IgG cut off control (concentrated) 500 µl VT-WE222C80 Borrelia IgM cut off control (concentrated) 500 µl MG Campylobacter IgA positive serum 200 µl MG Campylobacter IgG positive serum 200 µl MG Campylobacter IgA/IgG negative serum 200 µl MG Chlamydia IgA positive serum 200 µl MG Chlamydia IgG positive serum 200 µl MG Chlamydia IgA/IgG negative serum 200 µl MG CMV IgG positive serum 200 µl MG CMV IgM positive serum 200 µl MG CMV IgG/IgM negative serum 200 µl MG EBV IgG positive serum 200 µl MG EBV IgM positive serum 200 µl MG EBV IgG/IgM negative serum 200 µl VT-WE102C60 EBV IgG cut off control (concentrated) 500 µl VT-WE102C80 EBV IgM cut off control (concentrated) 500 µl MG Helicobacter IgA positive serum 200 µl MG Helicobacter IgG positive serum 200 µl MG Helicobacter IgA/IgG negative serum 200 µl VT-WE243C60 Helicobacter IgG cut off control (concentrated) 500 µl VT-WE243C40 Helicobacter IgA cut off control (concentrated) 500 µl VT-WE130C60 HSV IgG cut off control (concentrated) 500 µl MG Parvovirus B19 IgG positive serum 200 µl

6 6 Controls; continued MG Parvovirus B19 IgM positive serum 200 µl MG Parvovirus B19 IgG/IgM negative serum 200 µl MG Rubella IgG positive serum 200 µl MG Toxoplasma IgG positive serum 200 µl MG Toxoplasma IgM positive serum 200 µl MG Toxoplasma IgG/IgM negative serum 200 µl MG Treponema IgG positive serum 200 µl MG Treponema IgG/IgM negative serum 200 µl VT-WE150C60 Treponema IgG cut off control (concentrated) 500 µl VT-WE150C80 Treponema IgM cut off control (concentrated) 500 µl MG Yersinia IgA positive serum 200 µl MG Yersinia IgG positive serum 200 µl MG Yersinia IgA/IgG negative serum 200 µl VT-WE242C60 Yersinia IgG cut off control (concentrated) 500 µl VT-WE242C40 Yersinia IgA cut off control (concentrated) 500 µl VT-WE242C80 Yersinia IgM cut off control (concentrated) 500 µl CONJUGATES MG VT-WE MG MG VT-WE MG MG VT-WE recomblot / recomline IgA Conjugate EcoBlot / LINE IgA Conjugate recomblot / recomline IgG Conjugate recomblot / recomline IgG Conjugate EcoBlot / LINE IgG Conjugate recomblot / recomline IgM Conjugate recomblot / recomline IgM Conjugate EcoBlot / LINE IgM Conjugate 500 µl 700 µl 500 µl 1,4 ml 700 µl 500 µl 1,4 ml 700 µl

7 7 ACCESSORIES & REAGENTS MG Dilutionbuffer for recomline (10x concentrated) 100 ml MG Dilutionbuffer for recomline (10x concentrated) 500 ml MG Washing Buffer A for recomline (10x concentrated, contains phosphate buffer, NaCL, KCl, detergent and preservatives: methylisothiazolone and oxypyrione) 100 ml MG Washing Buffer A for recomline (10x concentrated, contains phosphate buffer, NaCL, KCl, detergent and preservatives: methylisothiazolone and oxypyrione) 500 ml MG Washing Buffer B for recomblot (10x concentrated, contains phosphate buffer, NaCL, KCl, detergent and preservatives) 100 ml MG Washing Buffer B for recomblot (10x concentrated, contains phosphate buffer, NaCL, KCl, detergent and preservatives) 1000 ml MG Washing Buffer for recomblot Rubella (10x concentrated, contains Tris buffer, NaCL, detergent, preservatives, phenol red and proteins) 100 ml VT-WE Dilution- / Washbuffer (10x concentrated) 50 ml MG TMB Substrate Solution for recomblot / recomline 40 ml NEW! VT-WE BCIP/NBT Substrate Solution for Genzyme-Virotech Line tests - ready-to-use 57 ml MG Avidity Reagents for recomblot / recomline 25 tests VT-WE Incubationtray with 8 cavities 1 pcs. MG Incubationtray with 30 cavities, white 1 pcs. MG VT-WE300.30S VT-WE300.30W MG VT-WE300.48S VT-WE300.48W Incubationtray with 30 cavities, black for use with the ProfiBlot 48 Incubationtray with 30 cavities, black for use with the ProfiBlot 48 Incubationtray with 30 cavities, white for use with the ProfiBlot 48 Incubationtray with 48 cavities, black for use with the ProfiBlot 48 Incubationtray with 48 cavities, black for use with the ProfiBlot 48 Incubationtray with 48 cavities, white for use with the ProfiBlot 48 1 pcs. 1 pcs. 1 pcs. 1 pcs. 1 pcs. 1 pcs.

8 8 AUTOMATION ZZ-MAB MedTec s AutoBlot 3000 Benchtop Western Blot processor for accurate and highly reproducible results Compact design Processes up to 20 strips Controlled incubation times, dispensed volumes and stringent washes Stores up to 10 user-defined methods Walk away processing Tubing easy to clean and change ZZ TECAN ProfiBlot 48 Fully automated Western Blot analysis Standardization of Western blot analysis higher accuracy and reproducibility On board storage of up to 20 different methods Precise reagent delivery system Unique color code for every reagent Optional integrated CCD system for scanning of strips Unique reagent-saving feature Password protection preventing unauthorized interference with the assay procedure BlotWare software for easy programming of methods MG BLOTrix Reader The BLOTrix Reader digitalize Immunoblot teststrips straigth from their wells in a washer tray through employment of innovative 3D Scan Technology. Results can be directly transferred, analysed and archived in the BLOTrix Software. Innovative 3D Scan Technology Digitalization of immunoblot teststrips in 30 seconds No handling of single strips required Controlled directly from within the BLOTrix Software Compatible to ProfiBlot 48 Trays Processes up to 48 Strips in one operation MG recomscan Software for the automatic detection and interpretation of recomblot, recomline of MIKROGEN and Line tests of Genzyme-Virotech. Easy to connect to the laboratory EDP (electronic data processing). exact clipping of strips high sensitivity band detection test specific result interpreter comfortable manual editing definition of worklists standardization reduction of error sources increase of efficiency Please ask our local representative whether a product is available in your country or not. Not each product is distributed by BIOMEDICA GRUPPE in each country! We at BIOMEDICA GRUPPE always try to serve you as best as we can. In case you are searching for a kit not included in this list, please do not hesitate to contact us. Please ask our local representative for our ELISA Immunoassays.

9 9 NOTES

10 10 NOTES

11 11 NOTES

12 12 CONTACT ADDRESSES ALBANIA BOSNIA & HERZEGOVINA BULGARIA BIOMEDICA MEDIZINPRODUKTE GmbH & Co KG Divischgasse 4, 1210 Wien Phone Fax a.dedic@bmgrp.at BIOMEDICA d.o.o. Holiday Inn Zmaja od Bosne Sarajevo Phone Fax a.dedic@bmgrp.at SOFBIOLIFE-BIOMEDICA Ltd. 52, Gen. Gurko Str. Floor 5,1000 Sofia Phone Fax office@biomedica-bg.eu CROATIA HUNGARY MACEDONIA Biomedica Dijagnostika d.o.o. V Ravnice Zagreb Phone Fax a.dedic@bmgrp.at BIOMEDICA Hungària Kft. Ribáry u Budapest Phone , Fax biomed@biomedica.hu BIOMEDICA MEDIZINPRODUKTE GmbH & Co KG Divischgasse 4, 1210 Wien Phone Fax a.dedic@bmgrp.at JASIKA d.o.o. Remetinecka cesta 115, Zagreb Phone Fax ivan.mestrovic@jasika.hr POLAND ROMANIA SERBIA BIOMEDICA POLAND Sp. z. o o. Ul. Raszynska Piaseczno Phone Fax biomedica@bmgrp.pl CYBER SRL Str. Smaranda Braescu nr. 20D sector 1, cod , Bucharest Phone Fax dan.pavel@cybermed.ro BIOMEDICA MP d.o.o. Djordja Pantelica 31, Zemun Phone Fax bjelenic@biomedicamp.com SLOVAKIA SLOVENIA BIOMEDICA Slovakia s.r.o. Drobného 27, Bratislava Phone Fax biomedica@biomedica.sk WBL-MASTER BIOMEDIS M.B.. Slokanova 12, 2000 Maribor Phone Fax info@biomedis-mb.si

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