Material Safety Data Sheet IT VIBE Sample Purification Kit

Transcription

1 Material Safety Data Sheet IT VIBE Sample Purification Kit 1. PRODUCT INFORMATION Trade Name: Buffer 1A Kit Number: ASAY-ASY-0500 Manufacturer Information BioFire Defense, LLC 79 West 4500 South, Suite 14 Salt Lake City, Utah 84107, USA ph (801) , Number for Information: COMPOSITION / INFORMATION ON INGREDIENTS CHEMICAL NAME: PERCENT: CAS #: Guanidine >50% Octoxynol >10% Notice: The buffer is an aqueous solution that consists of a mixture of ingredients and has not been tested as a whole. Preparations (mixtures) that contain less than one percent by weight or volume of non-carcinogenic dangerous ingredients are not considered dangerous, unless there is evidence to the contrary. The normal safety precautions for handling chemicals should always be observed. 3. HAZARDOUS IDENTIFICATION HAZARD: Harmful irritant. Causes irritation to skin, eyes and respiratory tract. Harmful if swallowed or inhaled. NFPA Rating Health: 2 Flammability: 0 Reactivity: 0 4. FIRST AID MEASURES Eye contact: Skin contact: Inhalation: Ingestion: Check for and remove any contact lenses and immediately flush eyes with copious amounts of water. Seek medical attention. Immediately flush skin with plenty of water for at least 15 minutes. Cover irritated skin with an emollient. Remove contaminated clothing. Seek medical attention. Remove to fresh air. Seek medical attention. Immediately seek medical attention. If swallowed, induce vomiting as directed to do so by medical personnel. Loosen tight clothing. 5. FIREFIGHTING MEASURES Suitable Extinguishing Media: Unsuitable Extinguishing Media: Explosion Hazard: Other Information: Use foam, carbon dioxide, water spray or dry chemical powder. Foam and water spray may cause frothing, but are still effective. None Self-contained breathing apparatus and protective clothing. Not Established Development of toxic fumes in the event of fire. 6. ACCIDENTAL RELEASE Clean-up Procedure: Dilute with water and absorb with liquid absorbent-material and dispose. Ventilate area and wash affected area. If large spill, use water spray to reduce vapors. ASAY-PRT-0510 Rev 03 Issued 5/14 Page 1 of 11

2 7. HANDLING AND STORAGE Handling: Storage: Avoid eye and skin contact. Do not ingest. Avoid breathing vapors. Store at room temperature. Keep container closed and away from direct sunlight. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Personal protective equipment: Respiratory protection Exhaust ventilation or other engineering controls Hand protection Compatible chemical resistant gloves Eye protection Chemical safety goggles or face shield Body protection Lab coat Change contaminated clothing. Wash hands after working with substances or preparations. 9. PHYSICAL AND CHEMICAL PROPERTIES Physical state/form Solubility in water 10. STABILITY AND REACTIVITY Stability: Substance to be avoided: Hazardous combustion or decomposition products: 11. TOXICOLOGICAL INFORMATION Toxicological Data Guanidine Octoxynol Target organ(s) or System(s): Routes/Symptoms of exposure: Skin Contact Eye Contact Inhalation Ingestion Additional Information: Colorless Liquid Soluble Stable Oxidizing agents CO X and some metallic oxides Acute oral toxicity, rat (LD50): 475 mg/kg; Irritation skin, rabbit: 500 mg/24h severe; Irritation eye, rabbit: ug moderate; Investigated as a mutagen Acute oral toxicity, rat (LD50): 1800 mg/kg Respiratory tract, gastrointestinal tract, central nervous system, skin, blood, kidneys, reproductive system, liver or eyes. May cause irritation; may be harmful if absorbed through the skin. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. May cause severe eye irritation. Redness, watering, and itching characterize inflammation of the eye. May be harmful if inhaled. May be irritating to mucous membranes and upper respiratory tract. May cause neurological disturbances. Causes irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting and diarrhea. This product should be handled with the normal caution accorded to chemicals. Additional harmful properties cannot be ruled out. 12. ECOLOGICAL INFORMATION 13. DISPOSAL CONSIDERATIONS 14. TRANSPORT INFORMATION 15. REGULATORY INFORMATION Not Established. The products of degradation are less toxic than the product itself. Observe all Federal, State and local laws regulating chemical waste. Processing, use or contamination of this product may change waste management options. Contact supplier for information regarding transportation for this material. U.S. Federal Regulations Octoxynol: TSCA 8(a) PAIR; TSCA 8(b) inventory; TSCA 8(d) H and S data reporting (1996) SARA 311/312 MSDS distribution chemical inventory hazard identification: Immediate (Acute) and Delayed (Chronic) Health Hazard SARA 302/304/311/312 hazardous chemicals Guanidine: SARA 311/312:; Acute: Yes; Chronic: No 16. OTHER INFORMATION ASAY-PRT-0510 Rev 03 Issued 5/14 Page 2 of 11

3 Not for food, drug, household, agricultural or cosmetic use. The above information is correct to the best of our knowledge. The user should make independent decisions regarding completeness of the information based on all sources available. BioFire Defense, LLC shall not be held liable for any damage resulting from handling or from contact with the above product. 1. PRODUCT INFORMATION Trade Name: Buffer 1B Kit Number: ASAY-ASY-0500 Manufacturer Information BioFire Defense, LLC 79 West 4500 South, Suite 14 Salt Lake City, Utah 84107, USA ph (801) , Number for Information: COMPOSITION / INFORMATION ON INGREDIENTS 3. HAZARDOUS IDENTIFICATION CHEMICAL NAME: PERCENT: CAS #: Isopropanol >90% HAZARD: Flammable liquid and vapor. Harmful if swallowed, inhaled or absorbed through the skin. Causes severe eye irritation. Damages respiratory tract, central nervous system, eye, lens and cornea. May cause skin irritation. NFPA Rating Health: 1 Flammability: 3 Reactivity: 0 4. FIRST AID MEASURES Eye contact: Skin contact: Inhalation: Ingestion: Immediately flush eyes with plenty of running water. Seek medical attention immediately. In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated clothing. Get medical attention. Remove to fresh air. Get medical attention immediately. Get medical attention immediately. Do not induce vomiting unless directed to do so by medical personnel. Loosen tight clothing. 5. FIREFIGHTING MEASURES Suitable Extinguishing Media: Unsuitable Extinguishing Media: Explosion Hazard: Water spray, carbon dioxide, dry chemical powder, or foam. None. Use an approved/certified respirator or equivalent. Highly flammable/explosive in the presence of open flames, sparks and static discharge. Vapor may travel a considerable distance to ignition source and flash back. Container explosion may occur under fire conditions. Flashpoint Open cup: 53.4ºF (11.9ºC) Autoignition Temp ºF (399.05ºC) 6. ACCIDENTAL RELEASE Precautionary Measures Clean-up Procedure: 7. HANDLING AND STORAGE Large spills: Evacuate area and shut off all ignition sources. Large spills: Respirator, chemical safety goggles, rubber boots, and heavy rubber gloves. Small spills can be diluted with water and mopped up or absorbed with an inert dry material and placed in an appropriate waste container. For large spill cleanup, use vapor-suppressing foam to reduce vapors, and absorb spill with liquid absorbent-material. Use non-sparking tools to remove saturated absorbent and move to disposal area. Ventilate and wash affected area. ASAY-PRT-0510 Rev 03 Issued 5/14 Page 3 of 11

4 Handling: Storage: Keep away from heat, sparks and flame. Avoid eye and skin contact. Avoid breathing vapor. Avoid ingesting. Avoid flammable material. Store at room temperature. Keep container closed and in a well-ventilated area. ASAY-PRT-0510 Rev 03 Issued 5/14 Page 4 of 11

5 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Personal protective equipment: Respiratory protection Hand protection Eye protection Body protection Airborne Exposure Limits: OSHA Permissible Exposure Limit (PEL): STEL: 1225 mg/m3 STEL: 500 ppm TWA: 980 mg/m3 TWA: 400 ppm ACGIH Threshold Limit Value (TLV): STEL: 1230 mg/m3 STEL: 500 ppm TWA: 983 mg/m3 TWA: 400 ppm NIOSH REL: STEL: 1225 mg/m3 STEL: 500 ppm TWA: 980 mg/m3, Period: 10 hours TWA: 400 ppm, Period: 10 hours Wear appropriate respirator when ventilation is inadequate. Compatible chemical resistant gloves Chemical safety goggles or face shield Lab coat 9. PHYSICAL AND CHEMICAL PROPERTIES Physical state/form Colorless Liquid Odor Characteristic Freezing Point ºF (-88.83ºC) Boiling point 82.55ºC (180.6ºF) Vapor density 2.07 (Air = 1) Vapor pressure Not available Specific gravity (Water = 1) Solubility in water Soluble Evaporation Rate 1.7 compared to (n-butyl ACETATE=1) 10. STABILITY AND REACTIVITY Stability: Stable Conditions to be avoided: Strong heating Substance to be avoided: Oxidizing agents Hazardous combustion or decomposition products: CO, CO TOXICOLOGICAL INFORMATION Toxicological Data RTECS Number Target organ(s) or System(s): Route/Symptoms of exposure: Skin Contact Eye Contact Inhalation Ingestion Additional Information: Acute oral toxicity (LD50): 3600 mg/kg [Mouse]; Acute dermal toxicity (LD50): mg/kg [Rabbit]. NT Respiratory tract, skin, central nervous system, eye, lens or cornea. May cause irritation; may be harmful if absorbed through the skin. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. Non-permeator. May cause severe eye irritation. Redness, watering, and itching characterize inflammation of the eye. Hazardous if inhaled. Hazardous if ingested This product should be handled with the normal caution accorded to chemicals. Additional harmful properties cannot be ruled out. 12. ECOLOGICAL INFORMATION 13. DISPOSAL CONSIDERATIONS Not Established. The products of degradation are less toxic than the product itself. Observe all Federal, State and local laws regulating chemical waste. Processing, use or contamination of this product may change waste management options. ASAY-PRT-0510 Rev 03 Issued 5/14 Page 5 of 11

6 14. TRANSPORT INFORMATION 15. REGULATORY INFORMATION DOT/IATA Flammable liquid N.O.S. (Isopropanol) Hazard Class: 3 Shipper must be hazardous goods certified in compliance with 49CFR and IATA Resolution 618. When product is shipped as part of a kit, contact supplier for proper transportation method. U.S. Federal Regulations (ISOPROPYL ALCOHOL): TSCA 4(a) final test rules; TSCA 8(b) inventory; TSCA 8(d) H and S data reporting (1986); TSCA 12(b) one time export; SARA 302/304/311/312 hazardous chemicals; SARA 311/312 MSDS distribution chemical inventory hazard identification: Fire Hazard, Immediate (Acute) and Delayed (Chronic) Health Hazards; SARA 313 toxic chemical notification and release reporting State Regulations (ISOPROPYL ALCOHOL): Pennsylvania RTK: (environmental hazard, generic environmental hazard); Massachusetts RTK 16. OTHER INFORMATION Not for food, drug, household, agricultural or cosmetic use. The above information is correct to the best of our knowledge. The user should make independent decisions regarding completeness of the information based on all sources available. BioFire Defense, LLC shall not be held liable for any damage resulting from handling or from contact with the above product. 1. PRODUCT INFORMATION Trade Name: Buffer 1C Kit Number: ASAY-ASY-0500 Manufacturer Information BioFire Defense, LLC 79 West 4500 South, Suite 14 Salt Lake City, Utah 84107, USA ph (801) , Number for Information: COMPOSITION / INFORMATION ON INGREDIENTS CHEMICAL NAME: PERCENT: CAS #: Guanidine >50% Ethanol >20% Methanol 0-1% Notice: The buffer is an aqueous solution that consists of a mixture of and has not been tested as a whole. Preparations (mixtures) that contain less than one percent by weight or volume of non-carcinogenic dangerous ingredients are not considered dangerous, unless there is evidence to the contrary. The normal safety precautions for handling chemicals should always be observed. 3. HAZARDOUS IDENTIFICATION HAZARD: Flammable liquid and vapor. Harmful if swallowed, inhaled or absorbed through the skin. May cause eye or skin irritation. Contains material which may cause damage to blood, kidneys, reproductive system, liver, gastrointestinal tract, respiratory tract, skin, central nervous system or eyes. NFPA Rating Health: 2 Flammability: 2 Reactivity: 0 4. FIRST AID MEASURES Eye contact: Skin contact: Inhalation: Ingestion: Immediately flush eyes with copious amounts of water. Seek medical attention immediately. In case of contact, immediately flush skin with plenty of water for at least 15 minutes. Cover the irritated skin with an emollient. Remove contaminated clothing. Seek medical attention. Remove to fresh air. Seek medical attention immediately. Seek medical attention immediately. Loosen tight clothing such as a collar, tie, belt, or waistband. 5. FIREFIGHTING MEASURES ASAY-PRT-0510 Rev 03 Issued 5/14 Page 6 of 11

7 Suitable Extinguishing Media: Unsuitable Extinguishing Media: Explosion Hazard: Other Information: Water spray, carbon dioxide, dry chemical powder, or foam. None. Wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Risks of explosion of the product in presence of static discharge, sparks, and open flame. Vapor may travel a considerable distance to ignition source and flash back. Container explosion may occur under fire conditions. Flammable liquid; development of toxic fumes in the event of fire. 6. ACCIDENTAL RELEASE Precautionary Measures: Clean-up Procedure: 7. HANDLING AND STORAGE Handling: Storage: Large spills: Evacuate area and shut off all ignition sources. Large spills: Respirator, chemical safety goggles, rubber boots, and heavy rubber gloves. Small spills can be flushed with water and mopped up or absorbed with an inert dry material and placed in an appropriate waste container. For large spill cleanup, ventilate the area using vapor-suppressing foam or water spray. Absorb spill with inert liquid absorbent-material. Use non-sparking tools to remove saturated absorbent, or other absorbent material and move to disposal area. Avoid eye and skin contact. Do not ingest. Avoid breathing vapor. Avoid flammable material. Keep container closed. Store at room temperature away from heat, sparks and flame and out of direct sunlight. Isolate from oxidizing materials. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Personal protective equipment: Respiratory protection Hand protection Eye protection Body protection Airborne Exposure Limits: OSHA Permissible Exposure Limit (PEL): 1000 ppm (TWA) (ethanol) 200 ppm (TWA) for methanol ACGIH Threshold Limit Value (TLV): System of local and/or general exhaust. If the exposure limit is exceeded, or ventilation is inadequate, wear a respirator. Compatible chemical resistant gloves Chemical safety goggles or face shield Lab coat 1000 ppm (TWA), A4 - not classifiable as a human carcinogen (ethanol) 200 ppm (TWA), 250 ppm (STEL) skin, for methanol 9. PHYSICAL AND CHEMICAL PROPERTIES Physical state/form Color Odor Solubility in water Liquid Colorless Characteristic Soluble 10. STABILITY AND REACTIVITY Stability: Stable Conditions to be avoided: Heat, flames and ignition sources Substance to be avoided: Oxidizing agents, metals and acids Hazardous combustion or decomposition products: CO X, NO X, HCl, and some metallic oxides. 11. TOXICOLOGICAL INFORMATION Toxicological Data Guanidine Ethanol Target organ(s) or System(s): Route/Symptoms of exposure: Skin Contact Eye Contact Inhalation Ingestion Acute oral toxicity, rat (LD50): 475 mg/kg; Irritation skin, rabbit: 500 mg/24h severe; Irritation eye, rabbit: ug moderate; Investigated as a mutagen Acute dermal toxicity, rabbit: mg/kg (METHANOL); Acute toxicity of vapor, rat LC50: ppm 4 hours Respiratory tract, gastrointestinal tract, CNS, skin, blood, kidneys, reproductive system, liver or eyes. Can cause blindness, CNS depression, drowsiness, narcotic effect and heart damage. May be harmful or cause irritation if absorbed through the skin. Skin inflammation characterized by itching, scaling, reddening, or blistering. May cause severe eye irritation. Inflammation of the eye is characterized y redness, watering, itching, and pain. Hazardous if inhaled. Symptoms include coughing and shortness of breath. May cause blindness if swallowed. May cause neurological disturbances or irritation to the gastrointestinal tract and mucous membranes. Symptoms include nausea, vomiting, and diarrhea. ASAY-PRT-0510 Rev 03 Issued 5/14 Page 7 of 11

8 12. ECOLOGICAL INFORMATION 13. DISPOSAL CONSIDERATIONS 14. TRANSPORT INFORMATION Not available. The products of degradation are less toxic than the product itself. Observe all Federal, State and local laws regulating chemical waste. Processing, use or contamination of this product may change waste management options. DOT/IATA Flammable liquid N.O.S. (ethanol, methanol) Hazard class: 3 Shipper must be hazardous goods certified in compliance with 49CFR and IATA Resolution 618. When product is shipped as part of a kit, contact supplier for proper transportation method. 15. REGULATORY INFORMATION U.S. Federal Regulations Guanidine: SARA 311/312: acute=yes; chronic=no Ethanol: TSCA 8(b) inventory; SARA 311/312 (MSDS distribution): acute=yes, chronic=yes; SARA 313 (toxic chemical notification); SARA 30 2/304/311/312 hazardous chemicals; SARA 313 toxic chemical notification and release reporting 16. OTHER INFORMATION Not for food, drug, household, agricultural or cosmetic use. The above information is correct to the best of our knowledge. The user should make independent decisions regarding completeness of the information based on all sources available. BioFire Defense, LLC shall not be held liable for any damage resulting from handling or from contact with the above product. 1. PRODUCT INFORMATION Trade Name: Buffer 2 Kit Number: ASAY-ASY-0500 Manufacturer Information BioFire Defense, LLC 79 West 4500 South, Suite 14 Salt Lake City, Utah 84107, USA ph (801) , Number for Information: COMPOSITION / INFORMATION ON INGREDIENTS 3. HAZARDOUS IDENTIFICATION CHEMICAL NAME: PERCENT: CAS #: Ethanol >60 % Methanol 0-4% HAZARD: Flammable liquid and vapor. Harmful if swallowed, inhaled or absorbed through skin. Vapor harmful. Affects central nervous system. May cause blindness. Causes irritation to skin, eyes, and respiratory tract. May affect liver, blood, and reproductive system. NFPA Rating Health: 1 Flammability: 3 Reactivity: 0 4. FIRST AID MEASURES Eye contact: Skin contact: Inhalation: Immediately flush eyes with copious amounts of water. Seek medical attention. Immediately wash skin with soap and copious amounts of water for at least 15 minutes. Remove contaminated clothing. Seek medical attention for overexposure. Remove to fresh air. Seek appropriate medical attention. ASAY-PRT-0510 Rev 03 Issued 5/14 Page 8 of 11

9 Ingestion: Seek medical attention immediately. Induce vomiting as directed by medical personnel. 5. FIREFIGHTING MEASURES Suitable Extinguishing Media: Unsuitable Extinguishing Media: Explosion Hazard: Other Information: Water spray, carbon dioxide, dry chemical powder, or foam. None. Self-contained breathing apparatus and protective clothing. Vapors may travel a considerable distance to ignition source and flash back. Container explosion may occur under fire conditions. Flashpoint Not determined (57ºF (14ºC) for 95% ethanol) Explosion limits 3.3% Lower 19% Upper Autoignition Temp. 750ºF (389ºC) Flammable liquid; development of toxic fumes in the event of fire. 6. ACCIDENTAL RELEASE Precautionary Measures: Clean-up Procedure: 7. HANDLING AND STORAGE Handling: Storage: Large spills: Evacuate area and Shut off all ignition sources. Large spills: Respirator, chemical safety goggles, rubber boots, and heavy rubber gloves. Small spills can be flushed with large amounts of water. For large spill cleanup, use vapor-suppressing foam to reduce vapors, and absorb spill with liquid absorbent-material. Use non-sparking tools to remove saturated absorbent, or other absorbent material, and forward it to disposal area. Ventilate and wash affected area. Avoid eye and skin contact. Avoid breathing vapor. Avoid flammable material. Keep away from heat, sparks and flame. Store at room temperature. Keep container closed. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Personal protective equipment: Respiratory protection Hand protection Eye protection Body protection Airborne Exposure Limits: OSHA Permissible Exposure Limit (PEL): 1000 ppm (TWA) for ethyl alcohol 200 ppm (TWA) for methyl alcohol ACGIH Threshold Limit Value (TLV): If the exposure limit is exceeded, wear a supplied air, full-facepiece respirator, airlined hood, or full-facepiece self-contained breathing apparatus. Compatible chemical resistant gloves Chemical safety goggles or face shield Lab coat 1000 ppm (TWA), A4 - not classifiable as a human carcinogen for ethyl alcohol 200 ppm (TWA), 250 ppm (STEL) skin, for methyl alcohol 9. PHYSICAL AND CHEMICAL PROPERTIES Physical state/form Liquid Color Colorless Odor Characteristic Freezing Point Approx. -55ºC Boiling point 80ºC at 760mm Hg Vapor density 1.6 (air = 20ºC Vapor pressure 44.6 mm 20ºC Specific gravity Solubility in water Soluble Density (air=1) 10. STABILITY AND REACTIVITY Stability: Stable Conditions to be avoided: Strong heating, open flames and sparks. Substance to be avoided: Alkali metals, ammonia, oxidizing agents, peroxides, acids, acid anhydrides, halogens. Hazardous combustion or decomposition products: CO and CO 2 ASAY-PRT-0510 Rev 03 Issued 5/14 Page 9 of 11

10 11. TOXICOLOGICAL INFORMATION Toxicological Data Ethanol (ethyl alcohol) Methanol (methyl alcohol) Target organ(s) or System(s): Routes of exposure: Skin Contact Eye Contact Inhalation Ingestion Symptoms of exposure: oral rat LD50: 7060 mg/kg; inhalation rat LC50: 20,000 ppm/10h; Irritation data, eye, rabbit: 500 mg/24h moderate; Investigated as a mutagen. oral rat LD50: 5628 mg/kg; inhalation rat LC50: ppm/4h; skin rabbit LD50: mg/kg; Irritation data,skin,rabbit: 20 mg/24h, Moderate; Investigated as a mutagen. Nerves, Liver, Kidneys, Eyes, and Cardiovascular, GI, Reproductive and Central Nervous systems. May be harmful if absorbed through the skin. May cause irritation; Skin inflammation characterized by itching, scaling, reddening, or blistering. Permeator. May cause severe eye irritation. Inflammation of the eye is characterized y redness, watering, itching, and pain. Hazardous if inhaled. Symptoms include coughing and shortness of breath. May be fatal or cause blindness if swallowed. May cause neurological disturbances or irritation to the gastrointestinal tract and mucous membranes. Symptoms include nausea, vomiting, and diarrhea. Can cause blindness, CNS depression, drowsiness, narcotic effect, birth defects and heart damage. 12. ECOLOGICAL INFORMATION Not Established 13. DISPOSAL CONSIDERATIONS 14. TRANSPORT INFORMATION 15. REGULATORY INFORMATION Observe all Federal, State and local laws regulating chemical waste. Processing, use or contamination of this product may change waste management options. DOT/IATA Flammable liquid N.O.S. (ethanol, methanol) Hazard class: 3 Shipper must be hazardous goods certified in compliance with 49CFR and IATA Resolution 618. When product is shipped as part of a kit, contact supplier for proper transportation method. U.S. Federal Regulations TSCA 8(b) inventory; SARA 311/312 (MSDS distribution): acute=yes, chronic=yes; SARA 313 (toxic chemical notification); SARA 302/304/311/312 hazardous chemicals; SARA 313 toxic chemical notification and release reporting: 16. OTHER INFORMATION Not for food, drug, household, agricultural or cosmetic use. The above information is correct to the best of our knowledge. The user should make independent decisions regarding completeness of the information based on all sources available. BioFire Defense, LLC shall not be held liable for any damage resulting from handling or from contact with the above product. 1. PRODUCT INFORMATION Trade Name: Buffer 3 Kit Number: ASAY-ASY-0500 Manufacturer Information BioFire Defense, LLC 79 West 4500 South, Suite 14 Salt Lake City, Utah 84107, USA ph (801) , ASAY-PRT-0510 Rev 03 Issued 5/14 Page 10 of 11

11 Number for Information: MSDS not required for these products under Occupational Safety and Health Administration standard Hazard Communication 29 CFR ASAY-PRT-0510 Rev 03 Issued 5/14 Page 11 of 11

12 1. PRODUCT INFORMATION Trade Name: VIBE Protease Kit Number: ASAY-ASY-0500 Manufacturer Information BioFire Defense, LLC 79 West 4500 South, Suite 14 Salt Lake City, Utah 84107, USA ph (801) , Number for Information: COMPOSITION / INFORMATION ON INGREDIENTS 3. HAZARDOUS IDENTIFICATION 4. FIRST AID MEASURES CHEMICAL NAME: PERCENT: CAS #: Protease <1% HAZARD: Sensitizer, may cause sensitization by inhalation and skin contact. Harmful by inhalation, do not breathe vapor. NFPA Rating Health: 1 Flammability: 0 Reactivity: 0 Eye contact: Skin contact: Inhalation: Ingestion: Check for and remove any contact lenses. Flush eyes with plenty of running water. Seek medical attention. Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Seek medical attention. Remove to fresh air. If breathing is difficult, seek medical attention. If swallowed, wash out mouth with water provided person is conscious. Seek medical attention. 5. FIREFIGHTING MEASURES Suitable Extinguishing Media: Unsuitable Extinguishing Media: Special Fire Fighting Procedures: Water spray, carbon dioxide, dry chemical powder or appropriate foam. None Wear self-contained breathing apparatus and protective clothing. 6. ACCIDENTAL RELEASE Precautionary Measures: Clean-up Procedure: 7. HANDLING AND STORAGE Storage: 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Personal protective equipment: Respiratory protection Hand protection Large spill: Wear respirator, chemical safety goggles, rubber boots and heavy rubber gloves. Absorb on sand or vermiculite and place in closed containers for disposal. Ventilate area and wash spill site. Store at 2-8 C. Exhaust ventilation or other engineering controls Compatible chemical resistant gloves ASAY-PRT-0510 Rev 03 Issued 5/14 Page 12 of 11

13 Eye protection Body protection 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Chemical safety goggles or face shield Lab coat Colorless to yellow liquid 10. STABILITY AND REACTIVITY Stability: Stable Hazardous combustion or decomposition products: Nature of decomposition products not known Hazardous Polymerization: Will not occur 11. TOXICOLOGICAL INFORMATION Route of exposure: Skin Contact Eye Contact Inhalation Ingestion Repeated exposure can cause: Target organ(s) or System(s): Additional Information: May be harmful if absorbed through the skin. May cause irritation. May cause allergic skin reactions. Not listed Harmful if inhaled. May be irritating to mucous membranes and upper respiratory tract. May cause allergic respiratory reactions. May be harmful if swallowed Asthma Lungs This product should be handled with the normal caution accorded to chemicals. Additional harmful properties cannot be ruled out. 12. ECOLOGICAL INFORMATION Not Available 13. DISPOSAL CONSIDERATIONS 14. TRANSPORT INFORMATION Observe all Federal, State and local laws regulating chemical waste. Processing, use or contamination of this product may change waste management options. Not regulated 15. REGULATORY INFORMATION N/A 16. OTHER INFORMATION Not for food, drug, household, agricultural or cosmetic use. The above information is correct to the best of our knowledge. The user should make independent decisions regarding completeness of the information based on all sources available. BioFire Defense, LLC shall not be held liable for any damage resulting from handling or from contact with the above product. ASAY-PRT-0510 Rev 03 Issued 5/14 Page 13 of 11