: PROTEIN GEL MIX/37.5:1/ACRYL:BIS SOLUTION

Transcription

1 Revision date: 10/09/2014 Version: 1.0 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Trade name Product code : PROTEIN GEL MIX/37.5:1/ACRYL:BIS SOLUTION : AB Relevant identified uses of the substance or mixture and uses advised against Use of the substance/mixture 1.3. Details of the supplier of the safety data sheet AmericanBio, Inc. 15 Erie Dr. Natick, MA USA T F info@americanbio.com Emergency telephone number Emergency number SECTION 2: Hazards identification 2.1. Classification of the substance or mixture Classification (GHS-US) Acute Tox. 4 (Oral) H302 Acute Tox. 4 (Dermal) H312 Acute Tox. 4 (Inhalation:dust,mist) H332 Skin Irrit. 2 H315 Skin Sens. 1 H317 Muta. 1B H340 Carc. 1B H350 STOT RE 1 H372 : Laboratory use/manufacturing component/research : (U.S.) :: (Outside U.S.) 2.2. Label elements GHS-US labeling Hazard pictograms (GHS-US) : Signal word (GHS-US) Hazard statements (GHS-US) Precautionary statements (GHS-US) : Danger GHS07 GHS08 : H302+H312+H332 - Harmful if swallowed, in contact with skin or if inhaled H315 - Causes skin irritation H317 - May cause an allergic skin reaction H340 - May cause genetic defects H350 - May cause cancer H372 - Causes damage to organs through prolonged or repeated exposure : P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P260 - Do not breathe mist/vapours/spray P261 - Avoid breathing mist/vapours/spray P264 - Wash hands, forearms and face thoroughly after handling P270 - Do not eat, drink or smoke when using this product P271 - Use only outdoors or in a well-ventilated area P272 - Contaminated work clothing should not be allowed out of the workplace P280 - Wear eye protection, protective clothing, protective gloves P301+P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell P302+P352 - IF ON SKIN: Wash with plenty of soap and water P304+P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing P308+P313 - IF exposed or concerned: Get medical advice/attention P312 - Call a POISON CENTER/doctor/physician if you feel unwell P314 - Get medical advice and attention if you feel unwell 10/09/2014 EN (English US) Page 1

2 P321 - Specific treatment (see SECTION 4 on this label) P330 - If swallowed, rinse mouth P332+P313 - If skin irritation occurs: Get medical advice/attention P333+P313 - If skin irritation or rash occurs: Get medical advice/attention P362 - Take off contaminated clothing and wash before reuse P362+P364 - Take off contaminated clothing and wash it before reuse P405 - Store locked up P501 - Dispose of contents/container to local/federal regulations 2.3. Other hazards 2.4. Unknown acute toxicity (GHS-US) No data available SECTION 3: Composition/information on ingredients 3.1. Substance Not applicable Full text of H-phrases: see section Mixture Name Product identifier % Classification (GHS-US) water, reagent grade, usp purified (CAS No) > 70 Not classified acrylamide (CAS No) Acute Tox. 3 (Oral), H301 Acute Tox. 3 (Dermal), H311 Acute Tox. 4 (Inhalation:dust,mist), H332 Skin Irrit. 2, H315 Skin Sens. 1, H317 Muta. 1B, H340 Carc. 1B, H350 STOT RE 1, H372 bisacrylamide (CAS No) < 1 Acute Tox. 4 (Oral), H302 Skin Irrit. 2, H315 Eye Irrit. 2A, H319 STOT SE 3, H335 SECTION 4: First aid measures 4.1. Description of first aid measures First-aid measures general First-aid measures after inhalation First-aid measures after skin contact First-aid measures after eye contact First-aid measures after ingestion : Never give anything by mouth to an unconscious person. If you feel unwell, seek medical advice (show the label where possible). : Assure fresh air breathing. Allow the victim to rest. Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER/doctor/physician if you feel unwell. : Immediately call a POISON CENTER or doctor/physician. Specific measures (see Consult a doctor/medical service on this label). Wash with plenty of soap and water. Wash contaminated clothing before reuse. If skin irritation occurs: Consult a doctor/medical service. Get medical advice/attention. Specific treatment (see Consult a doctor/medical service on this label). If skin irritation or rash occurs: Consult a doctor/medical service. : Rinse immediately with plenty of water. Obtain medical attention if pain, blinking or redness persist. : Rinse mouth. Do NOT induce vomiting. Obtain emergency medical attention. Call a POISON CENTER/doctor/physician if you feel unwell Most important symptoms and effects, both acute and delayed Symptoms/injuries Symptoms/injuries after inhalation Symptoms/injuries after skin contact Symptoms/injuries after ingestion : May cause genetic defects. May cause cancer. Causes damage to organs through prolonged or repeated exposure. : Danger of serious damage to health by prolonged exposure through inhalation. Harmful if inhaled. May cause an allergic skin reaction. : Repeated exposure to this material can result in absorption through skin causing significant health hazard. Harmful in contact with skin. Causes skin irritation. : Swallowing a small quantity of this material will result in serious health hazard Indication of any immediate medical attention and special treatment needed 10/09/2014 EN (English US) 2/8

3 SECTION 5: Firefighting measures 5.1. Extinguishing media suitable extinguishing media Unsuitable extinguishing media : Foam. Dry powder. Carbon dioxide. Water spray. Sand. : Do not use a heavy water stream Special hazards arising from the substance or mixture 5.3. Advice for firefighters Firefighting instructions Protection during firefighting : Use water spray or fog for cooling exposed containers. Exercise caution when fighting any chemical fire. Avoid (reject) fire-fighting water to enter environment. : Do not enter fire area without proper protective equipment, including respiratory protection. SECTION 6: Accidental release measures 6.1. Personal precautions, protective equipment and emergency procedures For non-emergency personnel Emergency procedures For emergency responders Protective equipment Emergency procedures : Evacuate unnecessary personnel. : Equip cleanup crew with proper protection. : Ventilate area Environmental precautions Prevent entry to sewers and public waters. Notify authorities if liquid enters sewers or public waters Methods and material for containment and cleaning up Methods for cleaning up 6.4. Reference to other sections See Heading 8. Exposure controls and personal protection. : Soak up spills with inert solids, such as clay or diatomaceous earth as soon as possible. Collect spillage. Store away from other materials. SECTION 7: Handling and storage 7.1. Precautions for safe handling Precautions for safe handling Hygiene measures : Wash hands and other exposed areas with mild soap and water before eat, drink or smoke and when leaving work. Provide good ventilation in process area to prevent formation of vapor. Use only outdoors or in a well-ventilated area. Avoid breathing mist/vapours/spray. Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Eliminate all ignition sources if safe to do so. Do not breathe mist/vapours/spray. : Do not eat, drink or smoke when using this product. Wash hands/forearms/face thoroughly after handling. Contaminated work clothing should not be allowed out of the workplace. Wash contaminated clothing before reuse Conditions for safe storage, including any incompatibilities Storage conditions Incompatible products Incompatible materials 7.3. Specific end use(s) : Keep only in the original container in a cool, well ventilated place away from : Direct sunlight. Keep container closed when not in use. : Strong bases. strong acids. SECTION 8: Exposure controls/personal protection 8.1. Control parameters : Sources of ignition. Direct sunlight. USA ACGIH ACGIH TWA (mg/m³) 0.03 mg/m³ 8.2. Exposure controls Personal protective equipment Hand protection Eye protection Skin and body protection : Avoid all unnecessary exposure. : Wear protective gloves. : Chemical goggles or safety glasses. : Wear suitable protective clothing. 10/09/2014 EN (English US) 3/8

4 Respiratory protection Other information : Wear approved mask. : When using, do not eat, drink or smoke. SECTION 9: Physical and chemical properties 9.1. Information on basic physical and chemical properties Physical state : Liquid Color : Colorless. Odor : characteristic. Odor threshold ph Relative evaporation rate (butyl acetate=1) Melting point Freezing point Boiling point Flash point Self ignition temperature Decomposition temperature Flammability (solid, gas) Vapor pressure Relative vapor density at 20 C Relative density Solubility Log Pow Log Kow Viscosity, kinematic Viscosity, dynamic Explosive properties Oxidizing properties Explosive limits 9.2. Other information SECTION 10: Stability and reactivity Reactivity Chemical stability Not established Possibility of hazardous reactions Not established Conditions to avoid Direct sunlight. Extremely high or low temperatures Incompatible materials strong acids. Strong bases Hazardous decomposition products fume. Carbon monoxide. Carbon dioxide. SECTION 11: Toxicological information Information on toxicological effects Acute toxicity LD50 oral rat : Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. 124 mg/kg (Rat) 10/09/2014 EN (English US) 4/8

5 LD50 dermal rat LD50 dermal rabbit bisacrylamide ( ) LD50 oral rat Skin corrosion/irritation Serious eye damage/irritation Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity IARC group National Toxicology Program (NTP) Status Reproductive toxicity Specific target organ toxicity (single exposure) 400 mg/kg (Rat) 1885 mg/kg (Rabbit) 390 mg/kg (Rat) : Causes skin irritation. : Not classified : May cause an allergic skin reaction. : May cause genetic defects. : May cause cancer. 2A - Probably Carcinogenic to Humans 3 - Reasonably anticipated to be Human Carcinogen : Not classified : Not classified Specific target organ toxicity (repeated exposure) Aspiration hazard Potential Adverse human health effects and symptoms Symptoms/injuries after inhalation Symptoms/injuries after skin contact Symptoms/injuries after ingestion : Causes damage to organs through prolonged or repeated exposure. Causes damage to organs through prolonged or repeated exposure : Not classified : Based on available data, the classification criteria are not met. Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. : Danger of serious damage to health by prolonged exposure through inhalation. Harmful if inhaled. May cause an allergic skin reaction. : Repeated exposure to this material can result in absorption through skin causing significant health hazard. Harmful in contact with skin. Causes skin irritation. : Swallowing a small quantity of this material will result in serious health hazard. SECTION 12: Ecological information Toxicity LC50 fish 1 EC50 Daphnia 1 LC50 fish 2 EC50 Daphnia 2 Threshold limit other aquatic organisms 1 Threshold limit other aquatic organisms mg/l (96 h; Salmo gairdneri (Oncorhynchus mykiss); Flow-through system) 230 mg/l (24 h; Daphnia magna; Flow-through system) 100 mg/l (96 h; Lepomis macrochirus) 98 mg/l (48 h; Daphnia magna; Flow-through system) 56 mg/l (96 h; Pimephales promelas) 60 mg/l (48 h; Daphnia magna; Flow-through system) Persistence and degradability PROTEIN GEL MIX/37.5:1/ACRYL:BIS SOLUTION Persistence and degradability Not established. Biochemical oxygen demand (BOD) Chemical oxygen demand (COD) ThOD BOD (% of ThOD) bisacrylamide ( ) Persistence and degradability 0.97 g O²/g substance 1.3 g O²/g substance 2.14 g O²/g substance 45 % ThOD Biodegradability in water: no data available Bioaccumulative potential PROTEIN GEL MIX/37.5:1/ACRYL:BIS SOLUTION Bioaccumulative potential Not established. BCF fish mg/kg (480 h; Oryzias latipes) 10/09/2014 EN (English US) 5/8

6 BCF fish 2 Log Pow mg/kg (960 h; Cyprinus carpio) bisacrylamide ( ) Bioaccumulative potential No bioaccumulation data available Mobility in soil Other adverse effects Other information : Avoid release to the environment. SECTION 13: Disposal considerations Waste treatment methods Waste disposal recommendations Ecology - waste materials SECTION 14: Transport information In accordance with DOT No dangerous good in sense of transport regulations Additional information Other information : Dispose in a safe manner in accordance with local/national regulations. Dispose of contents/container to local/federal regulations. : Avoid release to the environment. : No supplementary information available. ADR Transport document description Packing group (ADR) Hazard identification number (Kemler No.) Classification code (ADR) : UN N/A : N/A : N/A : N/A Transport by sea Air transport SECTION 15: Regulatory information US Federal regulations water, reagent grade, usp purified ( ) Listed on the United States TSCA (Toxic Substances Control Act) inventory Listed on the United States TSCA (Toxic Substances Control Act) inventory Listed on SARA Section 313 (Specific toxic chemical listings) RQ (Reportable quantity, section 304 of EPA's List of Lists) : bisacrylamide ( ) 5000 lb Listed on the United States TSCA (Toxic Substances Control Act) inventory International regulations CANADA EU-Regulations 10/09/2014 EN (English US) 6/8

7 Classification according to Regulation (EC) No. 1272/2008 [CLP] Classification according to Directive 67/548/EEC or 1999/45/EC Not classified National regulations Listed on IARC (International Agency for Research on Cancer) Listed as carcinogen on NTP (National Toxicology Program) US State regulations U.S. - California - Proposition 65 - Carcinogens List U.S. - California - Proposition 65 - Developmental Toxicity U.S. - California - Proposition 65 - Reproductive Toxicity - Female Yes Yes Yes U.S. - California - Proposition 65 - Reproductive Toxicity - Male No significance risk level (NSRL) U.S. - Massachusetts - Right To Know List U.S. - New Jersey - Right to Know Hazardous Substance List U.S. - Pennsylvania - RTK (Right to Know) List SECTION 16: Other information Other information : None. Full text of H-phrases: see section 16: Acute Tox. 3 (Dermal) Acute toxicity (dermal) Category Acute Tox. 3 (Oral) Acute toxicity (oral) Category Acute Tox. 4 (Dermal) Acute toxicity (dermal) Category Acute Tox. 4 (Inhalation:dust,mist) Acute toxicity (inhalation:dust,mist) Category Acute Tox. 4 (Oral) Acute toxicity (oral) Category Carc. 1B Carcinogenicity Category 1B Eye Irrit. 2A Serious eye damage/eye irritation Category 2A Muta. 1B Germ cell mutagenicity Category 1B Skin Irrit. 2 Skin corrosion/irritation Category Skin Sens. 1 Skin sensitization Category STOT RE 1 Specific target organ toxicity (repeated exposure) Category STOT SE 3 Specific target organ toxicity (single exposure) Category H301 Toxic if swallowed H302 Harmful if swallowed H311 Toxic in contact with skin H312 Harmful in contact with skin H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H332 Harmful if inhaled H335 May cause respiratory irritation H340 May cause genetic defects H350 May cause cancer H372 Causes damage to organs through prolonged or repeated exposure SDS US (GHS HazCom 2012) 10/09/2014 EN (English US) 7/8

8 AmericanBio, Inc. does not make any representations, guaranties or warranties as to the accuracy of the information provided in this, which has been provided by a third party, is made in accordance with United States Global Harmonization System (GHS) initiative HAZCOM 2012 (Federal Register, Vol. 77, No. 58, Monday March 26, 2012/Rules and Regulations), and is intended only to describe the product for the purposes of health, safety and environmental requirements. It is expressly understood and agreed that AmericanBio, Inc. shall in no way be deemed or held to be obligated, liable, or accountable upon or under any guaranties or warranties, express or implied, statutory, by operation of law, or otherwise, in any manner or form, including any implied warranty of merchantability or fitness for a particular purpose, that in any way relates to or arises out of the information provided in this. 10/09/2014 EN (English US) 8/8