Eye infections. Hossain Jabbari, MD, MPH, ID & TM Infectious Diseases Dept., Digestive Diseases Research Institute (DDRI) TUMS

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2 Eye infections Hossain Jabbari, MD, MPH, ID & TM Infectious Diseases Dept., Digestive Diseases Research Institute (DDRI) TUMS

3 Eye: An overview

4 Eye: An overview The eye is one of the most complex parts of the body. There are more than a billion parts all working in synchronization. The eyesight is one of the most important senses, a fact supported by the amount of brain that is dedicated to process the information received through the eye Eye in spiritual concepts and as a communication tool!

5 Eye injuries: as an overview 1 Physical hazards: Trauma, Sharp injuries 2 Chemical Hazards: Chemical burns (Acid, alkaline), 3 Biological Hazards: bacteria, viruses, parasites, 4 Genetic hazards: coloboma,

6 Coloboma

7

8 Eye Anatomy (Cont d)

9 Eye Anatomy (Cont d)

10 Eye Anatomy (Cont d)

11 Eye Anatomy (Cont d)

12 Eye Anatomy

13 Eye Anatomy (Cont d)

14 Eye Anatomy (Cont d)

15 Eye Infections

16 External Eye Diseases

17 Rt. facial nerve paresis

18 Abscess of meibomian gland (meibomianitis )

19 Chalazion

20 Purulent dacryocystitis OD

21 Chronic dacryocysitis with abscess formation

22 Elephantiasis Nostras

23 Herpes Zoster

24 Internal hordeolum - a meibomian abscess

25 HSV I of the lid

26 Abscess of meibomian gland

27 Preseptal cellulitis

28 Trachoma with extensive superior tarsal conjunctival scarring

29 Varicella/ chickenpox: loss of lashes lower lid

30 Viral papilloma

31 Tularemia, oculoglandular

32 Herpes zoster ophthalmicus with Hutchinson's sign

33 Herpes zoster ophthalmicus

34 Conjunctiva

35 Conjunctiva (Cont d) The conjunctiva (plural conjunctivas or conjunctivae): Clear mucous membrane that covers the sclera (white part of the eye) and lines the inside of the eyelids. It helps lubricate the eye by producing mucus and tears

36 Conjunctiva (Cont d) Conjungtivitis ( Pink eye or Madras eye) : Inflammation of the conjunctiva Red eye (hyperaemia), irritation (chemosis) and watering (epiphora) of the eyes are symptoms common to all forms of conjunctivitis

37 Conjunctiva (Cont d) Conjungtivitis causes: Viral conjunctivitis Allergic conjunctivitis Bacterial conjunctivitis Chemical conjunctivitis Neonatal conjunctivitis is often defined separately due to different organisms

38 Viral conjunctivitis: Conjunctiva (Cont d) Adenovirus (the most common cause) HSV (the most problematic) Less common causes include:vzv, enterovirus 70, Coxsackie A24, molluscum contagiosum, vaccinia, HIV Rarely, during systemic infection ( influenza virus, EBV, paramyxovirus (measles, mumps, Newcastle), rubella)

39 Molluscum contagiosum: with follicular conjunctivitis

40 Conjunctiva (Cont d) Acute hemorrhagic conjunctivitis (AHC): A prominent hemorrhagic component soon appears that is characteristic of this infection Coxsackie group A24 (CA24) and enterovirus E70 (EV70) strains

41 Acute Hemorrhagic Conjunctivitis (AHC)

42 Conjunctiva (Cont d) Epidemic Keratoconjunctivitis (EKC): A type of adenovirus ocular infection Sudden onset of acute follicular conjunctivitis with watery discharge, hyperemia, chemosis, and ipsilateral preauricular lymphadenopathy Pharyngo Conjunctival Fever (PCF)

43 Adenoviral conjunctivitis

44 Viral keratoconjunctivitis

45 Epidemic Keratoconjunctivitis

46 Epidemic Keratoconjunctivitis

47 Conjunctiva (Cont d) Bacterial conjunctivitis : Streptococci Staphylococci Chlamydia GC

48 Bacterial Conjunctivitis

49 Bacterial conjunctivitis

50 Acute mucopurulent bacterial conjunctivitis

51 Conjunctiva (Cont d) Allergic conjunctivitis Itching and tears Seasonal conjunctivitis Rhino conjunctivitis

52 Allergic conjunctivitis

53 Conjunctiva (Cont d) Chemical conjunctivitis Due to either an acidic or alkali substance Litmus paper is an easy way to rule out the diagnosis ( Normal ph : ) Irrigation with copious water

54 Conjunctiva (Cont d) Neonatal conjunctivitis A form of bacterial conjunctivitis contracted by newborns during delivery GC, Chlamydia Chemical (Silver nitrate)

55 Cornea

56 Cornea (Cont d)

57 Cornea (Cont d) Keratitis: Keratitis is inflammation of the cornea Superficial Keratitis Deep Keratitis

58 Cornea (Cont d) Amoebic keratitis: (the most serious corneal infection) Acanthamoeba keratitis (AK) in contact lens wearers

59 Amoebic keratitis

60 Cornea (Cont d) KeratitisBacterial keratitis Staphylococcus aureus Pseudomonas aeruginosa

61 Bacterial Keratitis

62 Pseudomonas keratitis (suppurative)

63 Interstitial keratitis with congenital syphilis

64 Inactive interstitial keratitis in congenital syphilis

65 Corneal ulcer from bacterial infection

66 Cornea (Cont d) Fungal keratitis: Fusarium Candida

67 Cornea (Cont d) Viral keratitis: Herpes simplex keratitis (Dendritic ulcer) Herpes zoster keratitis

68 Dendritic keratitis HSV - active

69 Disciform keratitis (HSV)-active with neovascularization

70 HSV Disciform keratitis - active stage with neovascularization of cornea.

71 HSV keratitis & HSV iritis

72 Herpetic Keratitis

73 Cornea (Cont d) Parasititic Keratitis: Onchocercal keratitis : O. volvulus infection by infected blackfly bite River blindness

74 Scleritis & Episcleritis

75 Episcleritis

76 Scleritis

77 Scleritis

78 Episcleritis, sectoral

79 Retina

80 Infection of other parts of the eye

81 Uveitis Uvea: 1. Iris 2. Chroid 3. Cilliary body

82 Endogenous suppurative iritis

83 Cataracta complicata with chronic uveitis

84 TB Uveitis

85 Tuberculosis (TB) uveitis - iritis

86 Hypopyon

87 Trachoma with pannus crassus

88 Trachoma: a perfect photo of established trachoma with conjunctivitis, florid pannus, corneal scarring, and trichiasis

89 Leprosy: patient is blind due to leprotic uveitis and keratitis

90 Syphilis and Trachoma: tertiary syphilis with gumma distruction of nose and trachoma

91 Endophthalmitis

92 Pan-endophthalmitis

93 Diagnosis

94 Treatment

95 Thanks for your kind attention!

96

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