Comprehensive and Practical Brachytherapy March 04-8 March 2018, Ljubljana, Slovenia Day 1 Sunday 4 March 2018

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1 Day 1 Sunday 4 March 2018 Welcome and Summary of the course 13:00-13:20 15 introduction 13:20-13:50 30 Radioactivity Radioactivity: What we need to know Characteristics of LDR-PDR-HDR, radiobiological aspects, α/β-ratio and half time of Time dose patterns 13:50-14:20 30 repair, EQD2 concept 14:20-14:50 30 Tea break 14:50-15:20 30 Implantation rules Implantation and dosimetric rules, Paris system, ICRU 58 15:20-15:50 Applicator localization 30 and basic planning Performing CT- and MR-scans, digitizing applicator curve in TPS, visibility, numbering catheters, Dose prescription, Paris system Oesophagus 15:50-16:20 30 brachytherapy Bronchus 16:20-16:50 30 brachytherapy 1

2 Day 2 Monday 5 March 2018 Demonstration of prostate Discussion of participants variances 8:30-8:45 15 contouring homework 8:45-9:15 30 Isotope characteristics Different isotopes, Specific activity, HVL, energy, half life Prostate permanent GEC-ESTRO recommendations, indication, tools and requirements, performing 9:15-9:55 40 application, hazards, results Prostate temporary GEC-ESTRO recommendations, indication, tools and requirements, performing 9:55-10:25 30 application, hazards, results 10:25-10:55 30 Coffee break Automated treatment plan/ Building up a plan, peripheral positioning of sources, avoiding Volume implants - Prostate 10:55-11:25 30 high urethra and rectum dose, source separation, stranded sources vs. loose sources EK B 11:25-11:55 30 Dose calculation TG43 and limitations 11:55-12:25 30 Anal canal 12:25-13:25 60 Lunch 13:25-13: :45-14:15 30 Keloids JG Time dose patterns :25-15:55 30 Tea break Characteristics of LDR-PDR-HDR, radiobiological aspects, a/b-ratio and half time of repair, EQD2 concept Satellite lecture Company Demonstration of companies' activities Demonstration of prostate and breast applicators and material for prostate and breast Recontouring prostate example Permanent implantation Treatment Planning on TPS (Make a treatment plan within dose constraints) 2

3 Day 3 Tuesday 6 March Dose distribution Breast brachytherapy Dose optimization Coffee break APBI Concept of dose distribution from radioactive sources, dose gradient, inverse square law, absorption, anisotropy Indication, tools and requirements, performing application (open wound, closed wound, after oncoplastic surgery), hazards, results Manual / Geometric / Volume / Graphical / Inverse (penalties, weight function, dwell time gradient) GEC-ESTRO recommendations, indication, techniques (multicatheter, Mamosite, SAVI), results Bladder Endometrial Postoperative: Indication, tools and requirements, performing application, hazards, result Skin cancer JG Lunch Uncertainties All kind of uncertainties, applicator reconstruction errors, contouring uncertainties, source positioning errors, OAR movements, systematic errors, random errors, interfraction uncertainties, interapplication uncertainties, magnitude of uncertainties Definitive treatment: Indication, tools and requirements, performing application, Endometrial hazards, results Satellite lecture Company Demonstration of companies' activities Demonstration of gynaecological applicators and material for gynaecological Tea break Cervix implantation Treatment Planning on TPS (Make a treatment plan within dose constraints) JG JG 3

4 Day 4 Wednesday 7 March Demonstration of prostate recontouring example Demonstration of participants variances after recontouring. Demonstration of cervix Discussion of participants variances contouring homework Cervix Indication, tools and requirements, techniques, performing application Cervix Hazards, results, complications Coffee break GEC-ESTRO recommendations Concept of CTVIR and CTVHR, ICRU 89 report and ICRU reporting DVH How to use DVH, differential DVH, cumulative DVH, D98, D90, V100, D2cm3 JG Use of US, CT, and MR Imaging, slice thickness, MR sequences, MR distortions, Imaging dose evaluation Lunch Interstitial gynaecological Planning with gynaecological applicators Vagina cancer, recurrence endometrial cancer or cervical cancer, indication, tools and requirements, performing application, hazards, results Applicator localization on CT and MR, Applicator library, Optimization Satellite lecture Company Demonstration of companies' activities Demonstration of gynaecological applicators and material for gynaecological Tea break Cervix implantation Treatment Planning on TPS (Make a treatment plan within dose constraints) EK Recontouring cervix example 4

5 Day 5 Thursday 8 March Demonstration of cervix recontouring example Demonstration of participants variances after recontouring. GEC-ESTRO recommendations, indication, tools and requirements, performing H & N cancer application, Radiation safety \ Radiation HVL, distance, inverse square law, controlling systems of the machines, Geiger protection teller, contamination, safe radioactive sources, requirements treatment rooms Coffee break H & N cancer Hazards, complications, results Paediatrics Limb sarcomas, Sarcoma botryroides, prostate sarcoma, Paediatrics RMS Orbit and H&N (AMORE) Final remarks and certificate Lunch / all teachers 5

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