DOWNLOAD PDF P-53 AS A PROGNOSTIC AND PREDICTIVE INDICATOR DANIELA KANDIOLER AND RAIMUND JAKESZ

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1 Chapter 1 : Contents - Breast Cancer - Click to Cure Cancer Chapter 11 / p53 as a Prognostic and Predictive Indicator via cell cycle arrest, DNA repair, or cell death, to prevent the development and progression of malignant cells. The biomarker TP53 divides patients with neoadjuvantly treated esophageal cancer into 2 subgroups with markedly different outcomes. A p53 Research Group study. J Thorac Cardiovasc Surg ; Kandioler, on behalf of the pancho study directors, investigators and co-workers and the p53 research group. Personalized medicine p53 gene analysis for prediction of response to neoadjuvant therapy in esophageal cancer. Growing clinical evidence for the interaction of the p53 genotype and response to induction chemotherapy in advanced non-small cell lung cancer. J Thorac Cardiovasc Surg ; 5: TP53 genotype but not p53 immunohistochemical result predicts response to preoperative short term radiotherapy in rectal cancer. Ann Surg ; 4: A magnetic probe to retrieve broken metallic parts of instruments during laparoscopic procedures. Surg Endosc ; TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients. Clin Cancer Res ; 6 1: Acta Chir Austriaca ; 32 2: The TP53 genotype but not immunohistochemistry result is predictive of response to cisplatinbased neoadjuvant therapy in stage III non-small cell lung cancer. Ann Thorac Surg ; Long-term results after repeated surgical removal of pulmonary metastases. Molecular genetic differentiation between primary lung cancers and lung metastases of other tumors. Anwendung von p53 Gen Analysen in der thoraxchirugischen Onkologie am Beispiel des solitaeren pulmonalen Rundherdes. Acta Chir Austr ; J Thorac Cardiovasc Surg ; Carcinogen- specific mutations in the p53 tumor suppressor gene in lung cancer. Clonal evolution in a transforming 5q- syndrome. Assessing the TP53 marker type in patients treated with or without neoadjuvant chemotherapy for resectable colorectal liver metastases: Predicting response to neoadjuvant therapy in esophageal cancer with p53 genotyping: A fortuneteller s crystal ball or a viable prognostic tool? Strategy for prevention of cancers of the esophagus. Ann N Y Acad Sci ; 1: Transl Oncol ; 6 6: Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis. Hepatology ; 53 3: Verhage, Marcus Feith, David H. Wijnhoven, and Stephen J. Sontag Barrett s esophagus: Ann N Y Acad Sci ; A study of the p53 research group. Eur Surg ; 42 1: Current role of interdisciplinary strategies in the treatment of pulmonary metastases Memo ; 2: Cancer Res ; 69 1: Low p27 expression predicts early relapse and death in postmenopausal hormone receptorpositive breast cancer patients receiving adjuvant tamoxifen therapy. Clin Cancer Res ; 15 Turning the tables on surgical oncology: Eur Surg ; 40 6: HB-EGF is a paracrine growth stimulator for early tumor prestages in inflammation-associated hepatocarcinogenesis. J Hepatol ; Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy. Clin Cancer Res ; 14 6: Clin Cancer Res ; 14 7: New cellular tools reveal complex epithelial-mesenchymal interactions in hepatocarcinogenesis. Br J Cancer ; 99 1: Anticancer Res ; 27 3B: Breast Cancer Res Treat ; 3: Functional categories of TP53 mutation in colorectal cancer: Ann Oncol ; 17 5: Genetic detection of lymph node micrometastases: Transplantation ; 81 1: NORE1B, a candidate tumor suppressor, is epigenetically silenced in human hepatocellular carcinoma. J Clin Oncol ; 23 High nuclear grade and negative estrogen receptor are significant risk factors for recurrence in DCIS. Eur J Surg Oncol ; Anticancer Research ; Inherent growth advantage of pre malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor alpha. Br J Cancer ; Prognostic markers in breast cancer: Multiple chromosomal abnormalities in human liver pre neoplasia. Breast Cancer Res Treat ; The early response of pdependent proteins during radiotherapy in human rectal carcinoma and in adjacent normal tissue. Int J Oncology ; Sequential steroid hormone receptor measurements in primary breast cancer with and without intervening primary chemotherapy. Endocrine Relat Canc ; 10; Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation. Cell Death Differ ; Pattern of hormone receptor status of secondary contralateral breast cancers in patients receiving adjuvant tamoxifen. Clin Canc Res ;8: Young age as an independent adverse prognostic factor in Page 1

2 premenopausal patients with breast cancer. Clin Breast Cancer ; 3, [0] 16 Jakesz, R. Randomized adjuvant trial of tamoxifen and goserelin versus cyclophosphamide, methotrexate, and fluorouracil: Expression of the lung resistance-related protein in human and rat hepatocarcinogenesis. Br J Cancer ; 85 Clin Cancer Res ; 7: Different Transendothelial Migration behaviour pattern of blood monocytes derived from patients with benign and malignant diseases of the breast. Inhibition of proliferation and induction of apoptosis in soft tissue sarcoma cells by interferon-alpha and retinoids. Br J Cancer ; 80 9: Randomized trial of low-dose chemotherapy added to tamoxifen in patients with receptor-positive and lymph node-positive breast cancer. J Clin Oncol ; Neoadjuvante Chemotherapie bei Patientinnen mit Mammakarzinom. ZBL Chir ; Suppl 5: Survival after surgical treatment of recurrent pulmonary metastases. Eur J Cardiothorac Surg ; Chirurgische Behandlung von Lungenmetastasen. Clinical experience with minimally invasive thoracic surgery. Thorac Cardiovasc Surg ; 3: Komplikationen nach Lungenmetastasektomie bei Patienten mit vorangegangener Chemotherapie. P53 as a Prognostic and Predictive Indicator. Kurzfassung der Dissertation Kandioler What is the role of p53 database in cancer? Kandioler Biomarker driven approaches in esophageal cancer. Kandioler p53 adaptierte neoadjuvante Chemotherapie: Chirurgenkongress, Linz 37 D. Page 2

3 Chapter 2 : P53 research Daniela Kandioler Download Citation on ResearchGate p53 as a Prognostic and Predictive Indicator Cancer is a disease of genes, and the p53 gene appears to be the most frequently mutated gene associated with. TP53 germline mutation may affect response to anticancer treatments: Breast Cancer Res Treat ; 3: EBioMedicine ; 2 8: Assessing the TP53 marker type in patients treated with or without neoadjuvant chemotherapy for resectable colorectal liver metastases: A p53 Research Group study. Eur J Surg Oncol ; Strategy for prevention of cancers of the esophagus. Ann N Y Acad Sci ; 1: The biomarker TP53 divides patients with neoadjuvantly treated esophageal cancer into 2 subgroups with markedly different outcomes. J Thorac Cardiovasc Surg ; A study of the p53 research group. Eur Surg ; 42 1: Kandioler, on behalf of the pancho study directors, investigators and co-workers and the p53 research group. Growing clinical evidence for the interaction of thep53 genotype and response to induction chemotherapy in advanced non-small celllung cancer. J Thorac Cardiovasc Surg ; 5: Turning the tables on surgical oncology: Eur Surg ; 40 6: Breast Cancer Res Treat. Functional categories of TP53 mutation in colorectal cancer: Epub Mar 8. NORE1B, a candidate tumor suppressor, is epigenetically silenced in human hepatocellular carcinoma. Epub Feb 7. Genetic detection of lymph node micrometastases: The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: Epub Sep Inherent growth advantage of pre malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor alpha. Prognostic markers in breast cancer: High nuclear grade and negative estrogen receptor are significant risk factors for recurrence in DCIS. Eur J Surg Oncol. Multiple chromosomal abnormalities in human liver pre neoplasia. The early response of pdependent proteins during radiotherapy in human rectal carcinoma and in adjacent normal tissue. Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation. Sequential steroid hormone receptor measurements in primary breast cancer with and without intervening primary chemotherapy. Pattern of hormone receptor status of secondary contralateral breast cancers in patients receiving adjuvant tamoxifen. Expression of the lung resistance-related protein in human and rat hepatocarcinogenesis. Young age as an independent adverse prognostic factor in premenopausal patients with breast cancer. TP53 genotype but not p53 immunohistochemical result predicts response to preoperative short-term radiotherapy in rectal cancer. Acta Chir Austr ; 32 2: TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients. Different transendothelial migration behaviour pattern of blood monocytes derived from patients with benign and malignant diseases of the breast. The TP53 genotype but not immunohistochemical result is predictive of response to cisplatin-based neoadjuvant therapy in stage III non-small cell lung cancer. J Thorac Cardiovasc Surg. Inhibition of proliferation and induction of apoptosis in soft tissue sarcoma cells by interferon-alpha and retinoids. Molecular genetic differentiation between primary lung cancers and lung metastases of other tumors. Carcinogen-specific mutations in the p53 tumor suppressor gene in lung cancer. Page 3

4 Chapter 3 : p53 in the clinics Abstract. Cancer is a disease of genes, and the p53 gene appears to be the most frequently mutated gene associated with human cancer.p53 is crucially involved in numerous central pathways determining the life and death of a cell. Analysis of an intensively treated Li-Fraumeni family. Breast Cancer Res Treat. TP53 mutational status and benefit from adjuvant fluorouracil in stage III colon cancer patients. Accepted Editorial commentary by Katie S. Predicting response to neoadjuvant therapy in esophageal cancer with p53 genotyping: J Thorac Cardiovasc Surg ; The biomarker TP53 divides patients with neoadjuvantly treated esophageal cancer into 2 subgroups with markedly different outcomes. A p53 Research Group study. Strategy for prevention of cancers of the esophagus. Ann N Y Acad Sci ; 1: Transl Oncol ; 6 6: Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis. Hepatology ; 53 3: Verhage, Marcus Feith, David H. Wijnhoven, and Stephen J. Ann N Y Acad Sci ; A study of the p53 research group. Eur Surg ; 42 1: Cancer Res ; 69 1: Molecularly characterised xenograft tumour mouse models: Turning the tables on surgical oncology: Eur Surg ; 40 6: Kandioler, on behalf of the pancho study directors, investigators and co-workers and the p53 research group. Personalized medicine â p53 gene analysis for prediction of response to neoadjuvant therapy in esophageal cancer. Growing clinical evidence for the interaction of the p53 genotype and response to induction chemotherapy in advanced non-small cell lung cancer. J Thorac Cardiovasc Surg ; 5: HB-EGF is a paracrine growth stimulator for early tumor prestages in inflammation-associated hepatocarcinogenesis. J Hepatol ; New cellular tools reveal complex epithelial-mesenchymal interactions in hepatocarcinogenesis. Br J Cancer ; 99 1: Anticancer Res ; 27 3B: Breast Cancer Res Treat ; 3: Genetic detection of lymph node micrometastases: Transplantation ; 81 1: Ann Oncol ; NORE1B, a candidate tumor suppressor, is epigenetically silenced in human hepatocellular carcinoma. J Clin Oncol ; 23 High nuclear grade and negative estrogen receptor are significant risk factors for recurrence in DCIS. Eur J Surg Oncol ; Anticancer Research ; Inherent growth advantage of pre malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor alpha. Br J Cancer ; Prognostic markers in breast cancer: Multiple chromosomal abnormalities in human liver pre neoplasia. Breast Cancer Res Treat ; The early response of pdependent proteins during radiotherapy in human rectal carcinoma and in adjacent normal tissue. Int J Oncology ; Sequential steroid hormone receptor measurements in primary breast cancer with and without intervening primary chemotherapy. Endocrine Relat Canc ; 10; Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation. Cell Death Differ ; Pattern of hormone receptor status of secondary contralateral breast cancers in patients receiving adjuvant tamoxifen. Clin Canc Res ;8: Young age as an independent adverse prognostic factor in premenopausal patients with breast cancer. Expression of the lung resistance-related protein in human and rat hepatocarcinogenesis. TP53 genotype but not p53 immunohistochemical result predicts response to preoperative short- term radiotherapy in rectal cancer. Ann Surg ; 4: A magnetic probe to retrieve broken metallic parts of instruments during laparoscopic procedures. Surg Endosc ; Br J Cancer ; 85 Clin Cancer Res ; 7: Interleukindeficient mice and inflammatory bowel disease associated cancer development. Carcinogenesis ; 22 4: TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients. Clinical Cancer Research ; 6 1: Acta Chir Austr ; 32 2: Polytrauma induces increased expression of pyruvate kinase in neutrophils. Different Transendothelial Migration behaviour pattern of blood monocytes derived from patients with benign and malignant diseases of the breast. Chapter 4 : LEISTUNGSBERICHT theinnatdunvilla.com In the last several years, the literature has been saturated with new information about the prognostic/predictive value of traditional factors as well as the newly recognized biomarkers. Page 4

5 Chapter 5 : P u b l i k a t i o n s l i s t e - PDF 11 p53 as a Prognostic and Predictive Indicator Daniela Kandioler and Raimund Jakesz. Part V. Predictive Biomarkers in Body Fluids. Chapter 6 : chierurgie - Ã sterreichischer Chirurgenkongress Note: Citations are based on reference standards. However, formatting rules can vary widely between applications and fields of interest or study. The specific requirements or preferences of your reviewing publisher, classroom teacher, institution or organization should be applied. Chapter 7 : Publications Authored by Thomas Bachleitner-Hofmann PubFacts The biological functions of the p53 tumor suppressor make it a potential predictive marker. p53 theinnatdunvilla.comler p53 oncoprotein as a prognostic indicator in. Chapter 8 : Publications Authored by Sebastian F Schoppmann PubFacts Sonja Kappel, Elisabeth Janschek, Brigitte Wolf, Margaretha Rudas, Bela Teleky, Raimund Jakesz, Daniela Kandioler TP53 germline mutation may affect response to anticancer treatments: Analysis of an intensively treated Li-Fraumeni family. Chapter 9 : Biomarkers in Breast Cancer : Daniel F. Hayes : The p53 genotype was specific in providing prognostic as well as predictive information in patients with preoperative short-term radiotherapy for rectal cancer. In contrast, p53 immunohistochemistry did not contribute to either prognostic or predictive information. Page 5