ICNIRP/ARPANSA GUIDELINES need urgent review. Victor Leach
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1 ICNIRP/ARPANSA GUIDELINES need rgent review Victor Leach
2 ORSAA An Introdction Oceania Radiofreqency Scientific Advisory Association Inc., (ORSAA) is a Not-for-Profit scientific association. Fll members and advisory panel members are non-indstry scientists from varios scientific disciplines: epidemiology, microbiology, biochemistry, physics, occpational hygiene, psychology, environmental science, endocrinology, immnology, nerology, oncology, bilding biology, pharmacology. Associate members are spporters (mainly retired) who offer their expertise (teacher, accontants, nrses etc.) as volnteers We are not an Advocacy Grop. We are all volnteers. 2
3 Evalating the Strength of Evidence Many disciplines are involved ORSAA database - analytical tool to evalate the strength of evidence Over 3100 papers objective assessed and categorised ORSAA.org ( 3
4 Satellite Image of Victoria, Victorian Bshfires Black Satrday
5 ORSAA database ELF to SHF (radar freq) pblications Incldes ARPANSA papers (1354) and Emerits Prof Henry Lai papers (937) 5
6 Trigger Points for Precationary Approach Two main factors triggers: Strength of evidence Potential cost of doing nothing Fll biological explanation can take years: Asbestos (1898 to 1999): 101 yrs Water with cholera bacterim, Dr John Snow (1854 to 1883): 29 yrs Smoking Sir Richard Doll (1952 to smoking bans on aircraft): 48 yrs 6
7 ICRP and ICNIRP Philosophies ICRP = risk managers (Insrance) Risk may exist (X rays, gamma rays) Low radiation doses à Risk ICNIRP = Jdge 7 Certainty before action. Low exposre levels à No risk People being protected However not all children, the elderly, and some chronically ill
8 ICRP vs ICNIRP Philosophies ICRP Risk management approach <100 msv is a Precationary Approach sing ALARA msv is a millisievert a measre of radiation dose. No sch concept with EMR-RF we jst have reference levels (exposre) only. ICNIRP ( WHO 2002) Non-Risk management approach Bt notes children, the elderly, some chronically ill people lower tolerance for one or more forms of NIR exposre Precationary Approach not applied for these at-risk grops Waiting for established evidence of harm is not a recognised risk management approach 8
9 ORSAA Database Epidemiological UHF Stdies IARC (WHO) - RF-EMR Grop 2B Possible hman carcinogen May Mobile phones and Digital Enhanced Cordless Telecommnications (DECT) phones
10 In vitro (test tbe) stdies ARPANSA TRS -164 TR-164 Effect 46% vs No Effect 54% ORSAA Effect 68% vs No Effect 32% 10
11 In vivo( living organism) stdies TRS -164 TR-164 Effect 49% vs No Effect 51% ORSAA Effect 74% vs No Effect 26% 11
12 Reason for the difference ARPANSA TRS-164: Expert reviewer was not reqested to se the ARPANSA literatre database Reprodced the findings obtained from the UK Health Department Report of the independent Advisory Grop on Non-Ionising Radiation (AGNIR) [3]. in vitro / in vivo review section reprodced the UK AGNIR report findings Provocation stdies relied on UK AGNIR report, the Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) [5] and ICNIRP reviews. Ø inherited all the AGNIR flaws and deficiencies (Dr Sarah Starkey [4]) inclding: Scientific inaccracy - conclsions did not accrately reflect the evidence Stdies omitted, inclded in other sections bt withot any conclsions, or conclsions left ot - Oxidative stress was not given the coverage it deserved. Fertility effects, cognitive fnction and behavioral effects were all misrepresented. Evidence dismissed and ignored in conclsions 12 ARPANSA TRS-164 is an inaccrate assessment of the available science
13 In-vivo testing from Hman UHF stdies Organ or flids sampled Saliva; Blood (Haemoglobin, chromosomes & lymphocytes); Sperm; Skin; Aditory system; Core Temperatre; Pititary Hormones; Urine; Faeces; EEG stdies ECG stdies Effect Stdies Top 6 major Bio- No Effect Uncertain Effect categories Effect DNA damage, Biochemical changes Altered Enzyme Activity; Cell Irreglarities/ Damage/ Oxidative Stress; Cardiovasclar/ Vasclar Effects 13 Sorce : ORSAA database
14 In-vivo animal stdies - All UHF stdies Cmlative Exposre (h) Stdies Effect No Effect Uncertain Top Six Bio-Effect categories (# stdies in brackets) Grop h ( 4.2 d) Grop to 750 h (4.2 d to 1 month) Grop 3 > h (<1 yr) 366 (79%) 76 (76%) 85 (18%) 21 (21%) 14 (3%) 3 (3%) 1. Biochemical changes (167) 2. Altered Enzyme Activity (144) 3. Oxidative Stress (122) 4. Cell Irreglarities/ Damage (82) 5. Nero-behavioral Effects/ Cognitive Effects (53) 6. DNA damage/ Mtagenic /Genotoxic (42) 1. Biochemical changes (35) 2. Altered Enzyme Activity (33) 3. Oxidative Stress (29) 4. Cell Irreglarities/ Damage (18) 5. Apoptosis (Programmed cell death) (12) 6. DNA damage/ Mtagenic /Genotoxic (11) Biochemical changes (7) 2. Altered Enzyme Activity (6) 3. DNA damage/ Mtagenic /Genotoxic (4) 4. Oxidative Stress (4) 5. Sperm effects (4) 6. Apoptosis (Programmed cell death) (3) 14 Sorce : ORSAA database
15 Non-thermal Effects exposres: in vivo animal stdies SAR 2 W/kg 17 Sorce : ORSAA database
16 16 Simlated vs Real Mobile Phones Signal
17 All Microwave (UHF-SHF) Stdies Sorce: ORSAA Database RF Bioeffect smmary 17
18 Mobile Phone Base Station Epidemiological Stdies ORSAA database has 29 Stdies 4 No Effect stdies fnded: 3 x German Government and 1 x UK telecom 18
19 Smmary slide on in vivo hman testing associated with Mobile Phone towers 19 Not a single stdy in Astralia with objective biochemical markers to see if there is an impact on people s health arond Mobile Phone Base Stations (MPBS) Only one large poplation stdy (epidemiology) by Dr. Brce Hocking (ex Telstra CMO) and colleages fond increased cancer risk near broadcasting towers VHF (another sorce of RF- EMR) A stdy in Brazil fond 93.5% (6,724/7,191) of cancer deaths over 10 years have occrred within 500m of a MPBS. Risk decreased steadily with distance from MPBS. Several stdies done other contries have shown clear adverse effects sch as more DNA damage, increased oxidative stress, increased risk of diabetes, altered hormone levels in people near MPBS It is risky to install powerfl RF-transmitters near sensitive locations like homes, schools and hospitals. Lilienfield Report (1978) From systematic low-level plsed exposre of US Embassy staff in Moscow. ( mw/m 2 (3% of ICNIRP limit) GHz (5G 6 GHz), 6-8 hr/day 5 day/wk, 2-4 yrs Symptoms eczema, psoriasis, allergic and inflammatory reactions
20 20 Review of fnding sorces in ORSAA database
21 21 Review of research by Contry of Origin
22 US Defence Intelligence Agency (DIA) Report 1976 Animal experiments reported in open literatre have demonstrated the se of low level microwave signals to prodce death by heart seizre or by nerological pathologies reslting from breaching of the blood-brain barrier. (page viii) Personnel (military) exposed to microwave radiation below thermal levels experience more nerological, cardiovasclar, and haemodynamic distrbances than do their nexposed conterparts. (page 6) Sbjects (military personnel) exposed to microwave exhibited a variety of nerasthenic disorders against a backgrond of angiodystonia (abnormal changes in the tonicity of the blood vessels). The most common sbjective complaints were headache, fatige, perspiring, dizziness, menstral disorders, irritability, agitation, tension, drowsiness, sleeplessness, depression, anxiety, forgetflness and lack of concentration. (page 8) Long term non-thermal microwave irradiation of male mice evoked diffse changes in the testes. Sbseqent mating of the animals reslted in redction in the size of the litters (page 13) 22
23 Identified Risks Brain Tmors Other Cancers Cardiovasclar Disease Diabetes Nerodegeneration Mental illnesses Pregnancy Complications, Developmental Problems Immne Disorders Infertility/Sterility Chronic Illness Nisance Effects Sleep Disorders 23
24 Chronic Diseases. Does EMR have a Role? Top Health Brdens Cardiovasclar Disease Cancer Nerodegenerative diseases Mental illness Allergies RF-EMR bio effects with evidence Cardiac and vasclar effects, oxidative stress and effects on voltage-gated Ca2+ channels DNA damage, altered cell metabolism, altered gene expression, oxidative stress, inflammation. neronal damage (evidence of fnctional and histopathological changes), oxidative stress, metabolic changes, blood brain barrier damage. Nerobehavioral changes - anxiety, cognitive impairment, changes in nerotransmitters Serological evidence of elevation of IgE antibodies and Th2 cytokines, lowering of cytotoxic activity of white blood cells, mast cell degranlation 24
25 25 Conclsions Converging evidence on health effects. Non-thermal bio-effects are real Enogh SMOKE to say we have a FIRE Devices need a higher safety design standard Stronger consmer advice on safe se especially children Advice on safer se is hidden Needs to be very obvios The data together with best risk management practice sggests: A trigger point has been reach for adopting a proper Precationary Approach to this new RF-EMR technology
26 Extra Slides Follow Slides that followed were not sed 26
27 Crrent Astralian EMF- RF Reglation Reglator =Astralian Commnications Media Athority (ACMA) Radiocommnications Act S162 (3) (f) health and safety protection to persons who operate, work with or se wireless eqipment via the establishment of standards Inclsion of the precationary principle in the ACMA reglatory instrments wold place a reglatory brden on indstry which wold reqire strong jstification. The ACMA does not discern that jstification 27
28 28 Sorce Statista.com
29 Epidemiological Stdies of Note Interphone à glioma in the grop with the longest dration of se ( 1640 h) (OR=1.40; 95% CI 1.03to 1.89), higher for ispsilateral se and temporal tmors. Patients interviewed Tmor Organ 2708 Glioma Brain 2409 Meningioma Brain 1100 Acostic Neroma Acostic nerve (Vestiblar Schwannoma) 400 Parotid gland Salivary gland CERENAT mlticenter French case-control stdy Among heaviest sers (cmlative dration 896 h), time since first se was occasionally less than 5 years (11%) bt mostly 5 9 years (49%) and 10 years and more (40%). 33 % commercial agents or sales people 22% chief operating officers, prodction & operation managers 62% reported occpational mobile phone se. COSMOS Stdy (75,993) Self reported vs Telco sage figres 14% reported health effect following se 29
30 30 in vivo long-term (Near Field) animal stdies - UHF stdy The US FDA - nominated cell phone RFR emission for toxicology and carcinogenicity testing in 1999 Took a decade to start NPT stdy - 2-year stdy on rats & mice Hge $25 million stdy is the world s largest most careflly done stdy ever done on long term wireless health risks. Reporting started in Near-field exposre intensity was at low non-thermal or non-heating levels Evidence of Carcinogenic activity was rated as: Clear evidence; Some evidence; Eqivocal evidence of carcinogenic activity is demonstrated by stdies that are interpreted as showing a marginal increase of neoplasms that may be test agent related; No evidence; Inadeqate stdy. Mice Stdy showed no effects Exposre to Sprage Dawley (SD) Rats different Occrrence of these rare nerve sheath tmors were statistically significant and others where not Rare nerve tmors were fond being malignant schwannoma in the heart of male rats Same cells in nerves of the hman ear. Significant positive trends were fond for gliomas in male rats exposed to CDMA-modlated RF radiation Ditto heart Schwannomas in male rats exposed to GSM or CDMA-modlated RF
31 in vivo long-term (far-field) animal stdies - UHF stdy Ramazzini Institte in Italy. Long-term animal stdy - jst conclded Interim paper: Same rare nerve tmors were fond in male rats as in the NPT stdy. These rare nerve tmors also present in control male rats Same findings as NPT stdy. Reslts less convincing than NPT stdy. Does rat research inform hman health risk? Rats are the preferred animal models for carcinogenicity stdies Reglatory agencies rely on rodent carcinogenicity bioassay data à a given chemical à cancer in hmans. 31
32 32 Prof Henry Lai s life-time collection ORSAA database incorporates: ARPANSA database Prof Henry Lai s personal collection of 937 papers: 1. ELF-EMF-Apr1-comet-assay.docx (46 papers) 2. ELF-oxidative-effect docx (186 papers) 3. RFR nerological-effects docx (325 papers) 4. RFR-Apr1-comet-assay.docx ( 76 papers) 5. Electrohypersensitivity-50pg-2017.docx (124 papers) 6. Final RF oxidative stress papers (180 papers) Lai classified stdies as "Effect" or "No Effect" ORSAA classification different only 27 / 937 times 7 in new category "Uncertain Effect 10 Effect" to "No Effect" 10 "No Effect" to Effect. Good agreement on the final bio-effect category for each paper.
33 Chronic Diseases. Does EMR have a Role? Top Health Brdens Cardiovasclar Disease Cancer Nerodegenerative diseases Mental illness Allergies RF-EMR bio effects with evidence Cardiac and vasclar effects, oxidative stress and effects on voltage-gated Ca2+ channels DNA damage, altered cell metabolism, altered gene expression, oxidative stress, inflammation. neronal damage (evidence of fnctional and histopathological changes), oxidative stress, metabolic changes, blood brain barrier damage. Nerobehavioral changes - anxiety, cognitive impairment, changes in nerotransmitters Serological evidence of elevation of IgE antibodies and Th2 cytokines, lowering of cytotoxic activity of white blood cells, mast cell degranlation 33
34 34 ANRES research (190 individals srveyed)
35 What is the Precationary Approach? Simple definition of Precationary Approach: A risk management framework in the face of scientific ncertainty Not an admission of gilt Implementation of Precationary Approach Complex Reqires trst Fair and reasonable Transparent and open As Low As Reasonable Achievable (ALARA) As Low As Reasonable Practicable (ALARP) Both historical Precationary Approaches Lack strctre of proper Precationary Approach 35
36 Movie - Generation Zapped 36
37 Evidence of harmfl effects has been known for more than 40 years
38 Bio Effect Research: 1970 Conclsions* RF (Microwaves) may have both pathogenic effects and, nder certain conditions, a therapetic action on the hman organism Many aspects of this pressing problem remain almost totally neglected; in particlar, or information on the mechanism by which microwaves affect the hman organism is inadeqate Microwave radiation on the organism can be dealt with sccessflly (and the literatre material critically generalized) in its present state only by a team of scientists representing varios specialties It was established from stdy of the nonthermal (specific) action of radio waves that the changes that appear in the organism cannot be explained solely in terms of the amont of heat formed in it *Sorce: Inflence of Microwave Radiation on Man and Animals (1970) - NASA Translation
39 Bradford Hill System of Casation ORSAA database Uses Bradford Hill (BH) indexes for casation of cancer BH Criteria for casation Minimal conditions necessary to provide adeqate evidence of a casal relationship between an incidence and a possible conseqence 39
40 Bradford Hill System Moving from Association to Casation Temporal Relationship: Exposre mst precede the effect Strength: Strength of the association Relative Risk Dose Response Effect: Biological gradient Plasibility: Biological plasibility Experimental: Reprodcibility with repeated stdies Specificity: Specificity of the association Coherence: Coherence between case-to-effect interpretation with generally known facts abot disease Consistency: Consistency between independent stdies 40
41 Biology vs Physics views of EMR Interaction Biology: microwave radiofreqency transmissions à increases oxidative stress and DNA damage -> can case cancer Physics: photon energy cannot break covalent bonds à No DNA damage Bad science We know Chronic inflammation à cancer Cigarette smoke à cancer Toxins and atoimmne disease à cancer 41
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