Research and Technology Management

Transcription

1 Office of Technology Development - Sponsored Research Agreements Join us as we congratulate the Principal Investigators of new industry sponsored research agreements listed below: January 2012 Principal Investigator: Ingo K. Mellinghoff, MD Department/Program: Neurology/Neurology Service Project Title: Phase II Study of BKM120 for Patients with Recurrent Glioblastoma and Activated P13K Pathway Total Award Amount: $265,120 Award Date: 01/18/12 Awarding Agency: Dana-Farber/Partners CancerCare, Inc. Principal Investigator: Alison J. Moskowitz, MD Department/Program: Medicine/Lymphoma Service Project Title: Brentuximab Vedotin (SGN-35) in Transplant Eligible Patients with Relapsed or Refractory Hodgkin Lymphoma Total Award Amount: $497, Award Date: 01/04/12 Awarding Agency: Seattle Genetics, Inc. Principal Investigator: Gary Schwartz, MD Department/Program: Medicine/Melanoma and Sarcoma Service Project Title: A Phase I Study of AEB071, An Oral Protein Kinase C Inhibitor, in Patient with Metastatic Uveal Melanoma Total Award Amount: $772, Award Date: 01/06/12 Awarding Agency: Novartis Pharmaceuticals Corporation February 2012 Principal Investigator: Martee L. Hensley, MD Department/Program: Gynecologic Medical Oncology Project Title: A Randomized Controlled Study of Yondelis (Trabectedin) or Dacarbazine for the Treatment of Advanced Liposarcoma or Leiomyosarcoma Previously Treated with An Anthracycline and Ifosfamide Total Award Amount: $190,200 Award Date: 02/07/12 Awarding Agency: Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Principal Investigator: Peter Kijewski, PhD Department/Program: Imaging & Spectroscopic Physics Project Title: CRA GE Kijewski 1 Memorial Sloan- Kettering Cancer Center

2 Total Award Amount: $42,642 Award Date: 02/20/12 Awarding Agency: GE Healthcare Principal Investigator: Nikoletta Lendvai, MD, PhD Department/Program: Medicine/Hematology Service/Lymphoma Service Project Title: Phase 2 Study of Canfosfamide HCI for Injection (TELCYTA) in Combination in Refractory or Relapsed Mantle Cell Lymphoma (MCL), Difuse Large B Cell Lymphoma (DLBCL) and Multiple Myeloma (MM) Total Award Amount: $116,411 Award Date: 02/15/12 Awarding Agency: Telik, Inc. Principal Investigator: Michael Morris, MD Department/Program: Medicine/Genitourinary Oncology Service Project Title: A Phase I, Open-Label, Multicengre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumour Activity of Ascending Doses of AZD3514 in Patients with Metastatic Castration-Resistant Prostate Cancer Total Award Amount: $281,834 Award Date: 02/13/12 Awarding Agency: AstraZeneca Principal Investigator: Eileen O'Reilly, MD Department/Program: Medicine/Gastrointestinal Oncology Service Project Title: Retrospective Study of BRCA and P ALB2 Mutations and HR Deficiency in Pancreatic Cancer Total Award Amount: $20,850 Award Date: 02/20/12 Awarding Agency: Myriad Genetics Inc. Principal Investigator: Paul Paik, MD Department/Program: Medicine Project Title: A Phase I, Open-Label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumour Activity of Ascending Doses of AZD4547 in Patients with Advanced Solid Malignancies Total Award Amount: $219,400 Award Date: 02/02/12 Awarding Agency: Astra Zeneca Inc. Principal Investigator: Dana Rathkopf, MD, PhD Department/Program: Medicine / Genitourinary Oncology Service Project Title: Investigator Initiated Study: Establishing a Neo-Adjuvant Platform for Developing Targeted Agents: Degarelix Prior to Prostatectomy for Patients with Intermediate and High Risk Prostate Cancer. Total Award Amount: $221,596 2 Memorial Sloan- Kettering Cancer Center

3 Award Date: 02/21/12 Awarding Agency: Ferring Pharmaceuticals Principal Investigator: Gregory J. Riely, MD, PhD Department/Program: Medicine/Thoracic Oncology Service Project Title: A Phase II Study of the Selective BRAF Kinase Inhibitor GSK in Subjects with Advanced Non-Small Cell Lung Cancer and BRAF Mutations Total Award Amount: $211,373 Award Date: 02/07/12 Awarding Agency: GlaxoSmithKline/ICON Clinical Research, Inc. Principal Investigator: Naiyer A. Rizvi, MD Department/Program: Medicine/Thoracic Oncology Service Project Title: A Multi-Arm Phase I Study of BMS in Combination with Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, or Carboplatin/Paclitaxel in Subjects with Treatment-Naive Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) Total Award Amount: $403,435 Award Date: 02/01/12 Awarding Agency: Bristol-Myers Squibb Principal Investigator: William D. Tap, MD Department/Program: Melanoma and Sarcoma Service Project Title: A Randomized Phase 3, Multicenter, Open Labeled Study Comparing TH-302 in Combination with Doxorubicin vs. Doxorubicin Alone in Subjects with Locally Advanced Unressectable or Metastatic Soft Tissue Sarcoma Total Award Amount: $639,646 Award Date: 02/20/12 Awarding Agency: Threshold Pharmaceuticals/Sarcoma Alliance for Research Through Collaboration Principal Investigator: Yi-Wei Tang, MD, PhD, F(AAM), FIDSA Department/Program: Clinical Microbiology Project Title: SRA ACEA Biosciences Tang icelldx Total Award Amount: $32,500 Award Date: 02/25/12 Awarding Agency: ACEA Biosciences, Inc. March 2012 Principal Investigator: Dean F. Bajorin, MD Department/Program: Medicine/Genitourinary Oncology Project Title: Phase II Study of BKM120 in Metastatic Transitional cell Carcinoma of the Urothelium Total Award Amount: $109,469 3 Memorial Sloan- Kettering Cancer Center

4 Award Date: 03/07/12 Awarding Agency: Novartis Pharmaceuticals Corporation Principal Investigator: Jennifer Hay, PhD Department/Program: Psychiatry & Behavioral Sciences Project Title: Assessment of MAPK Pathway Activity in PBMCs Collected from Melanoma Patients Per and During Treatment with BMS Total Award Amount: $16,000 Award Date: 03/16/12 Awarding Agency: Bristol-Myers Squibb Principal Investigator: Jennifer Hay, PhD Department/Program: Psychiatry & Behavioral Sciences Project Title: Ipilimumab Treatment Kinetics: An Evaluation of Patient Perceptions and Quality of Life Total Award Amount: $16,000 Award Date: 03/16/12 Awarding Agency: Bristol-Myers Squibb Principal Investigator: Howard Scher, MD Department/Program: Medicine/Genitourinary Oncology Project Title: Coordinating Center Service Agreement Total Award Amount: $48,315 Award Date: 03/13/12 Awarding Agency: Agensys Inc. May 2012 Principal Investigator: Jason S. Lewis, PhD Department/Program: Radiology/Radiochemistry Service Project Title: SRA ContraFect Lewis Biodist Total Award Amount: $7, Award Date: 05/01/12 Awarding Agency: ContraFect Principal Investigator: Jedd D. Wolchok, MD, PhD Department/Program: Medicine/Melanoma and Sarcoma Service Project Title: Clinical Research Support Agreement for Study Protocol BRA Total Award Amount: $57,400 Award Date: 05/08/12 Awarding Agency: GlaxoSmithKline June 2012 Principal Investigator: Ross Levine, MD 4 Memorial Sloan- Kettering Cancer Center

5 Department/Program: Medicine/Human Oncology & Pathogenesis Program (HOPP) Project Title: Development of Sensitive Pharmacodynamic Assays, Including Jak2 Phosphorylation Assays, for MPN Patients Total Award Amount: $80,000 Award Date: 06/25/12 Awarding Agency: Sanofi-Aventis US Principal Investigator: Howard Scher, MD Department/Program: Medicine/Genitourinary Oncology Service Project Title: SRA Exellxis Scher CTC project for their phase III pain endpoint study Total Award Amount: $545,093 Award Date: 06/11/12 Awarding Agency: Exelixis, Inc. August 2012 Principal Investigator: Jorge A. Carrasquillo, MD Department/Program: Radiology/Nuclear Medicine Project Title: SRA GILEAD Larson GS-6624 with I-124 Total Award Amount: $76,838 Award Date: 08/10/12 Awarding Agency: Gilead Sciences Principal Investigator: Jorge A. Carrasquillo, MD Department/Program: Radiology/Nuclear Medicine Project Title: To Improve Immunotherapy of Human Melanoma by 20D7S PET Imaging Total Award Amount: $135,762 Award Date: 08/10/12 Awarding Agency: ImClone Systems, Inc. Principal Investigator: Neal Rosen, MD, PhD Department/Program: Medicine/Breast Cancer Medicine/Molecular Pharmacology & Chemistry Project Title: SRA Merck Rosen SCH Total Award Amount: $101,465 Award Date: 08/21/12 Awarding Agency: Merck & Co September 2012 Principal Investigator: Joseph P. Erinjeri, MD, PhD Department/Program: Radiology/Interventional Radiology Project Title: Optical Assessment of Intracellular Signaling Pathways in Live Cells Obtained A tier Percutaneous Needle Biopsy Using Dynamic Mass Redistribution 5 Memorial Sloan- Kettering Cancer Center

6 Total Award Amount: $41,990 Award Date: 09/05/12 Awarding Agency: Corning Incorporated Principal Investigator: Gary Ulaner, MD, PhD Department/Program: Radiology Project Title: FACBC PET and PEM as a Staging Tool and Indicator of Therapeutic Response in Breast Cancer Patients Total Award Amount: $78,000 Award Date: 09/25/12 Awarding Agency: General Electric Principal Investigator: James A. Fagin, MD Department/Program: Human Oncology & Pathogenesis Program (HOPP) Project Title: SRA AZ Project 56 Fagin Total Award Amount: $125,723 Award Date: 09/06/12 Awarding Agency: Dana-Farber/Partners CancerCare, Inc. October 2012 Principal Investigator: Mark Dunphy, DO Department/Program: Nuclear Medicine Project Title: PET Imaging of Cancer Patients Using 124I-PUH71: A Pilot Study Total Award Amount: $471, Award Date: 10/18/12 Awarding Agency: Samus Therapeutics LLC Principal Investigator: Vincent Laudone, MD Department/Program: Surgery/Urology Project Title: MTA In GE Laudone Determine the Feasibility and Scope of a Collaborative Joint Development Program Using GE Proprietary Myelin-Binding Fluorophore and Compact Instrumentation for Open and Minimally Invasive Surgeries Total Award Amount: $11,214 Award Date: 10/05/12 Awarding Agency: General Electric Principal Investigator: Howard Scher, MD Department/Program: Medicine/Genitourinary Oncology Project Title: CTC Lab Service Agreement Genentech Scher and Fleisher Total Award Amount: $189,537 Award Date: 10/15/12 Awarding Agency: Genentech, Inc. November Memorial Sloan- Kettering Cancer Center

7 Principal Investigator: David Finley, MD Department/Program: Thoracic Service Project Title: Cardiopulmonary Effects of Airway Spray Cryotherapy Total Award Amount: $152,500 Award Date: 11/30/12 Awarding Agency: CSA Medical, Inc. December 2012 Principal Investigator: Jedd D. Wolchok, MD, PhD Department/Program: Medicine/Melanoma and Sarcoma Service Project Title: 2012 Celgene Future leader in Hematology Award for Clinical Research in Hematology Total Award Amount: $ $7, Award Date: 12/03/12 Awarding Agency: Celgene Corporation Principal Investigator: James Eastham, MD Department/Program: Surgery/Urology Project Title: Sponsored Research Agreement between Exosome Diagnostics, Inc. and MSKCC Total Award Amount: $34,134 Award Date: 12/11/12 Awarding Agency: Exosome Diagnostics, Inc Principal Investigator: Malcolm Moore, DPhil Department/Program: Medicine/Division of Hematologic Oncology/Cell Biology Project Title: Arion Sponsored Research Total Award Amount: $177,803 Award Date: 12/31/12 Awarding Agency: Arion Pharmaceuticals 7 Memorial Sloan- Kettering Cancer Center