AGENDA. 7:40 am - 7:50 am Radical Prostatectomy Technique for Preservation of Urinary Continence and The Pagano Suture John Libertino, MD

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1 AGENDA Friday, September 8, 2017 SESSION I RADICAL PROSTATECTOMY The Mount Sinai Hospital, Stern Auditorium Moderators: David Albala, MD, Inderbir Gill, MD Expert Panel: Mani Menon, MD, Ashok Hemal, MD, Vipul Patel, MD 7:00 am 7:10 am Surgical Anatomy of Prostate Atsushi Takenaka, MD, PhD 7:10 am - 7:20 am Neural Supply of the Male Urethral Sphincter Thomas Bessede, MD 7:20 am - 7:40 am Foundations of Anatomic RALP - Continence Ash Tewari, MBBS, MCh 7:40 am - 7:50 am Radical Prostatectomy Technique for Preservation of Urinary Continence and The Pagano Suture John Libertino, MD 7:50 am - 8:00 am Nerve Sparing Techniques Vipul Patel, MD 8:00 am - 9:00 am LIVE SURGERY Surgeon: Ash Tewari, MBBS, MCh Moderator: Thomas Ahlering, MD Panel: Dipen Parekh, MD, John Davis, MD, Francesco Porpiglia, MD 9:00 am - 9:10 am A RARP Technique with Preservation of Pubovesical Ligament and Dorsal Venous Complex to Improve Early Functional Outcome Rajesh Ahlawat, MBBS, MCh 9:10 am - 9:20 am Strategies to Achieve Trifecta in Robotic Prostate Cancer Surgery David Lee, MD 9:20 am - 9:30 am 3D Imaging and Treatment Planning Francesco Porpiglia, MD 9:30 am - 9:40 am Newer Techniques in RARP / Fluorescent Guided Surgery Ashok Hemal, MD

2 9:40 am - 9:50 am Pelvic LND for Prostate Cancer - Worth the Full Effort or Skip? John Davis, MD 9:50 am - 10:00 am Robotic Salvage RPLND+PLND for Lymph Node Only Recurrent Prostate Cancer Inderbir Gill, MD 10:00 am - 10:10 am Extraperitoneal Radical Prostatectomy Jean Joseph, MD 10:10 am - 10:20 am Perineal Radical Prostatectomy Jihad Kaouk, MD 10:20 am - 10:30 am "Art" of Radical Prostatectomy Fabrizio Dal Moro, MD 10:30 am - 10:50 am Journey of Robotic Surgery Mani Menon, MD 10:50 am - 11:10 am BREAK /VISIT EXHIBITS SESSION II TREATING LOCALIZED DISEASE Moderator: Vipul Patel, MD Expert Panel: Ketan Badani MD, Francesco Porpiglia, MD, Michael Zelefsky, MD 11:10 am - 11:20 am Active Surveillance Deepak Kapoor, MD 11:20 am -11:30 am Brachytherapy Richard Stock, MD 11:30 am - 11:40 am Focal Therapy Ardeshir Rastinehad, DO 11:40 am - 11:50 am Radical Prostatectomy Prasanna Sooriakumaran, MD, PhD 11:50 am - 12:00 pm Radiotherapy Michael Zelefsky, MD 12:00 pm - 12:15 pm DEBATE: Best Method to Treat High Risk Cancer Moderator: Francesco Porpiglia, MD Radical Prostatectomy: Prasanna Sooriakumaran, MD, PhD Radiotherapy: Michael Zelefsky, MD

3 12:15 pm - 12:30 pm DEBATE: Best Method to Treat Low Risk Moderator: Ketan Badani, MD Focal Therapy: Ardeshir Rastinehad, DO Active Surveillance: Deepak Kapoor, MD 12:30 pm 1:30 pm LUNCH SYMPOSIUM AFTERNOON SESSIONS Choose one breakout session to attend. BREAKOUT A Stern Auditorium BREAKOUT B - 5 th Floor Annenberg, Room 205 (follow directional signs to elevators) Agendas for each session on the following pages.

4 BREAKOUT SESSION A Location: STERN AUDITORIUM 1:30 pm 1:50 pm Anatomical Foundations of RP Nerve Sparing Ash Tewari, MBBS, MCh 1:50 pm 2:50 pm LIVE SURGERY Surgeon: Ash Tewari, MBBS, MCh Moderator: Mani Menon, MD Panel: Craig Nobert, MD, Prasanna Sooriakumaran, MD, PhD, James Porter, MD, Jean Joseph, MD, Ketan Badani, MD ADVANCED PROSTATE CANCER Moderators: Bobby Liaw, MD, Vincent Laudone, MD Expert Panel: Bishoy Morris Faltas, MD, Philip Kantoff, MD, Kenneth Pienta, MD, Natasha Kyprianou, MD, PhD 2:30 pm 3:05 pm Disseminated Tumor Cells at the Time of Radical Prostatectomy - What is the Real Incidence? Kenneth Pienta, MD 3:05 pm 3:15 pm Functional Genomics Eric Schadt, PhD 3:15 pm 3:25 pm PTEN Signaling and Metabolism Ramon Parsons, MD, PhD 3:25 pm 3:45 pm BREAK / VISIT EXHIBITS 3:45 pm 4:00 pm DNA Damage and Repair Philip Kantoff, MD 4:00 pm 4:10 pm Gene-Oncogene Interactions Carlos Cordon-Cardo, MD, PhD 4:10 pm 4:20 pm Prostate Cancer Heterogeneity Ganesh Palapattu, MD 4:20 pm 4:30 pm Racial Disparities in Prostate Cancer Isaac Powell, MD 4:30 pm 4:50 pm ADT, Castration Resistance and Novel Chemotherapeutics in Prostate Cancer William Oh, MD

5 BREAKOUT SESSION A Location: STERN AUDITORIUM 4:50 pm 5:00 pm Overcoming Therapeutic Resistance in Advanced Prostate Cancer Natasha Kyprianou, MD, PhD 5:00 pm 5:10 pm Novel Approaches to Bone Metastasis in Prostate Cancer Alice Levine, MD 5:10 pm 5:20 pm Multimodal Treatment Paradigm in Early Metastatic Prostate Cancer Vincent Laudone, MD 5:20 pm 5:30 pm Oligometastatic Prostate Cancer Alex Kirschenbaum, MD 5:30 pm 5:40 pm Treatment of Primary Lesion in Metastatic Prostate Cancer Brian Francis Chapin, MD 5:40 pm 5:45 pm CONCLUDING REMARKS

6 BREAKOUT SESSION B Location: 5 th Floor Annenberg, Room: 205 SESSION I LOCALLY ADVANCED DISEASE Moderator: Kenneth Rosenzweig, MD 1:30 pm 1:45 pm Role of RT For High Risk Disease Richard Stock, MD 1:45 pm 2:00 pm Role of ADT with RT Michael Zelefsky, MD 2:00 pm 2:15 pm Role of PSMA In Locally Advanced Disease Markus Hohenfellner, MD 2:15 pm 2:30 pm CyberKnife Jonathan Haas, MD 2:30 pm 2:45 pm IMRT Shawn Zimberg, MD 2:45 pm 3:05 pm DEBATE: CyberKnife vs. IMRT Moderator: Richard Stock, MD CyberKnife: Jonathan Haas, MD IMRT: Shawn Zimberg, MD 3:05 pm 3:15 pm Neoadjuvant Systemic Therapy Brian Francis Chapin, MD 3:15 pm 3:35 pm BREAK / VISIT EXHIBITS SESSION II MORBIDITY AND QUALITY OF LIFE Moderators: Victor Nitti, MD, Steven A. Kaplan, MD 3:35 pm 3:45 pm Penile Rehabilitation and Pharmacologic Treatment of ED Natan Bar-Chama, MD 3:45 pm 4:05 pm Penile Implantation Post-RP Robert Valenzuela, MD 4:05 pm 4:15 pm Urethral Stricture Management Rajveer Purohit, MD, FACS, MPH 4:15 pm 4:25 pm Surgical Factors Influencing Early Continence Recovery Vincenzo Ficarra, MD, PhD

7 4:25 pm 4:35 pm Post-RP Incontinence Management Victor Nitti, MD 4:35 pm 4:55 pm DEBATE: Post-prostatectomy Incontinence: PFMT vs. Early Sling/AUS Moderator: Victor Nitti, MD PFMT: Steven A. Kaplan, MD Early Sling/AUS: Neil Grafstein, MD 4:55 pm 5:05 pm Treatment of LUTS Following RALP & RT Jerry Blaivas, MD 5:05 pm 5:15 pm QoL and Lifestyle Changes - General Health Perspective Jefferey Mechanick, MD 5:15 pm 5:25 pm QoL and Lifestyle Changes - Urology Perspective Philippa Cheetham, MD 5:25 pm 5:35 pm Complications in Robotic Surgery Distant from The Surgical Site Daniel Gainsburg, MD 5:35pm 5:45 pm Peri-operative Safety Initiatives Amanda Rhee, MD 5:45 pm 5:50 pm CONCLUDING REMARKS

8 Friday, September 8, 2017 NON-CME PROGRAM AGENDA * 5:50 pm 5:55 pm WELCOME The Mount Sinai Hospital, Stern Auditorium Ash Tewari, MBBS, MCh 5:55 pm 6:05 pm Research Discovery and Preclinical Development of Immunotherapy Drugs Robert Stein, MD, PhD 6:05 pm 6:15 pm Prostate Cancer Drug Development: Lessons Learned from the XTANDI Journey Lynn Seely, MD 6:15 pm 6:25 pm Role of Prostate Cancer Foundation in Supporting Prostate Cancer Research Jonathan Simons, MD 6:25 pm 6:35 pm Immuno-Oncology s Signal-to-Noise Problem: Developing Proof of Relevance for Novel MOAs Jeffrey M. Bockman, MD 6:35 pm 6:45 pm Integration of Imaging & Robotics: Robotic Platform of the 21st Century Gary Guthart, PhD 6:45 pm 6:55 pm Social Media in Medicine Nate Gross, MD 6:55 pm 7:00 pm CONCLUDING REMARKS *Not approved for CME credit.