January 10-12, Westin Harbour Castle Toronto, ON #CUOS19. cuos2019.org

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1 January 10-12, 2019 Westin Harbour Castle Toronto, ON #CUOS19 cuos2019.org

2 Scientific Program Committee Co-Chairs: Neil Fleshner, CUOG Aly-Khan Lalani, GUMOC Himu Lukka, GUROC Andy Evans, CNUP Tony Finelli, CUOG Martin Gleave, CUOG Anil Kapoor, KCRNC Wassim Kassouf, CUA Dean Ruether, GUMOC Fred Saad, CUOG Rob Siemens, CUAJ Alan So, CUA This program is an Accredited Group Learning Activity (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada, reviewed and approved by the Canadian Urological Association.

3 Canadian Uro-Oncology Summit 2019 January 10-12, 2019 Westin Harbour Castle Toronto, ON Thursday, January 10, 2019 Prostate Cancer and Bladder Cancer 07:00 07:45 Breakfast in Exhibit Hall 07:45 09:30 General Session 1: Prostate Cancer Diagnosis and Treatment of Localized Disease Chair: Tony Finelli 07:45 08:00 MRI: Where Do We Stand in 2019? Masoom Haider 08:00 08:15 Biomarkers: From Diagnosis to Risk Stratification Frederic Pouilot 08:15 08:30 Sequencing Issues Around ARPI Sebastien Hotte 08:30 08:45 Active Surveillance: Long-Term Data We Continue to Learn Lawrence Klotz 08:45 09:00 Current Radiotherapeutic Approaches to Treating Localized Disease Tamim Niazi 09:00 09:30 Panel Discussion 09:30 10:00 Health Break in Exhibit Hall 10:00 11:20 General Session 2: Emerging Diagnostics and Therapies in Advanced Prostate Cancer Chair: Sebastien Hotte 10:00 10:15 Imaging Prostate Cancer: Breakthroughs and Limitations Francois Benard 10:15 10:30 Theranostics and Radioligands: Will This Be the Breakthrough? Himu Lukka, Katherine Zukotynski 10:30 10:45 Treating M0 or nmcrpc Fred Saad 10:45 11:00 Is There a Role for Treating the Primary in mcspc? Rob Hamilton 11:00 11:20 Panel Discussion

4 11:20 12:10 Swipe Right to Treat? Evaluating nmcrpc patient management strategies Sebastien Hotte, Bobby Shayegan 12:10 13:30 Lunch in Exhibit Hall 13:30 14:30 Podium Session 1: Advanced Prostate Cancer, Testes Cancer & Kidney Cancer Chair: Fred Saad 14:30 14:50 Keynote Lecture 1: Prostate Cancer Martin Gleave Introduction: Neil Fleshner 14:50 15:00 Q & A 15:00 15:30 Case 1: Canadian Clinical Cases Chair: Martin Gleave Speakers: Joseph Chin, Alan So 15:30 16:00 Break in Exhibit Hall 16:00 17:00 General Session 3: Locally Advanced Kidney Cancer Regional Node Dissection in Clinically Positive, Advanced RCC 16:00 16:25 Lymph Node Dissection at the Time of Nephrectomy - Pro Ross Mason 16:25 16:45 Lymph Node Dissection at the Time of Nephrectomy - Con Luke Lavallée 16:45 17:00 Panel Discussion 17:00 18:00 Welcome Reception & Posters (Prostate Cancer)

5 Canadian Uro-Oncology Summit 2019 January 10-12, 2019 Westin Harbour Castle Toronto, ON Friday, January 11, 2019 Bladder Cancer and Kidney Cancer Chair: Aly-Khan Lalani 07:00 07:45 Breakfast in Exhibit Hall 07:45 12:00 Joint Sessions 07:45 08:05 Keynote Lecture 2: Five-Year Outlook in The Management of Metastatic Urothelial Carcinoma Joaquim Bellmunt Introduction: Aly-Khan Lalani 08:05 08:15 Q & A 08:15 08:35 Keynote Lecture 3: Predicting Response to Immune Checkpoint Blockade in Bladder Cancer Thomas Powles Introduction: Wassim Kassouf 08:35 08:45 Q & A 08:45 10:00 General Session 4: Potpourri of Bladder Cancer Research Across Canada (in Ted Talk style) Chairs: Wassim Kassouf, Aly-Khan Lalani 08:45 08:52 Adrian Fairey 08:52 08:59 08:59 09:06 Bernie Eigl 09:06 09:13 Koti Madhuri 09:13 09:20 Girish Kulkarni 09:20 09:27 Wassim Kassouf 09:27 09:34 David Berman 09:34 09:41 Yves Fradet 09:41 10:00 Panel Discussion 10:00 10:30 Break in Exhibit Hall

6 10:30 11:30 General Session 5: Debates on Controversial Topics in Urothelial Carcinoma Chair: Bobby Shayegan 10:30 10:50 Open vs RARC Adrian Fairey vs Girish Kulkarni 10:50 11:10 Neoadjuvant Chemo for All MIBC vs Neoadjuvant Chemotherapy Guided by Molecular Subtyping Nimira Alimohamed vs Peter Black 11:10 11:30 High-Grade UTUC: Neoadjuvant vs Adjuvant Chemotherapy Rodney Breau vs Kala Sridhar 11:30 12:00 Case 2: Cases from the Multidisciplinary Clinic Chair: Bobby Shayegan Speakers: Alex Zlotta, Som Mukherjee, Peter Cheung 12:00 13:30 Lunch in Exhibit Hall 13:30 14:30 Podium Session 2: Bladder Cancer & Other Chair: Nick Power 14:30 14:50 Keynote Lecture 4: Genomics in Uro-Oncology Paul Boutros Introduction: Rob Hamilton 14:50 15:00 Q & A 15:00 15:20 Keynote Lecture 5: Frailty in Older Adults With Urological Cancer: Why is it Important, and What Can We Do About it? Shabbir Alibhai Introduction: Neil Fleshner 15:20 15:30 Q & A 15:30 15:50 Keynote Lecture 6: New Horizons in the Management of Advanced Penile Cancer Philippe Spiess Introduction: Kevin Zorn 15:50 16:00 Q & A 16:00 16:30 Break in Exhibit Hall 16:30 17:30 General Session 6: Molecular Pathology of Bladder Cancer: At the Intersection of Genomics and Immunotherapy George Netto Chair: Andy Evans 17:30 18:30 Wine & Cheese Poster Session (Bladder, Testes & Others)

7 Canadian Uro-Oncology Summit 2019 January 10-12, 2019 Westin Harbour Castle Toronto, ON Saturday, January 12, 2019 Kidney Cancer and Prostate Cancer 07:00 16:00 Bladder Cancer Consensus Meeting :00 07:45 Breakfast with Exhibitors 07:45 09:30 General Session 7: mrcc: Evolution and Future Chair: Anil Kapoor 07:45 08:15 Cytoreductive Nephrectomy: Is There Still a Role for Nephrectomy in Patients with Metastatic RCC? Ricardo Rendon 08:15 08:45 Biomarkers in mrcc: Too Cold, Too Hot, or Just Right? Aly-Khan Lalani 08:45 09:15 Biopsy of the Small Renal Mass - Still Controversial? Tony Finelli 09:15 09:30 Panel Discussion 09:30 10:05 Keynote Lecture 7: Kidney Cancer - Post IO Therapies: Sequencing in RCC in the IO Era Thomas Powles Introduction: Anil Kapoor 10:05 10:15 Q & A 10:15 10:45 Health Break in Exhibit Hall 10:45 11:35 Podium Session 3: Locally Advanced Prostate Cancer Armen Aprikian 11:35 11:55 General Session 8: Prostate Cancer Locally Advanced Chair: Rob Siemens 11:35 11:55 High-Risk Prostate Cancer Debate: Intensity-Modulated Radiation Therapy (IMRT) vs Brachytherapy Michael Brundage vs Lawrence Klotz 11:55 12:00 Closing Remarks Chairs: Neil Fleshner, Aly-Khan Lalani, Himu Lukka

8 FOUNDING SPONSORS SUPPORTING SPONSORS CONTRIBUTORS Proudly supported and co-sponsored by Canadian Network of Urological Pathologists

January 10-12, Westin Harbour Castle Toronto, ON #CUOS19. cuos2019.org

January 10-12, Westin Harbour Castle Toronto, ON #CUOS19. cuos2019.org January 10-12, 2019 Westin Harbour Castle Toronto, ON #CUOS19 cuos2019.org Scientific Program Committee Co-Chairs: Neil Fleshner, CUOG Aly-Khan Lalani, GUMOC Himu Lukka, GUROC Andy Evans, CNUP Tony Finelli,

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