ACADEMIC DETAILS. Surname: Constantinou First Name: Constantina Middle Name:

Transcription

1 A. APPOINTMENT AND CONTACT DETAILS Surname: Constantinou First Name: Constantina Middle Name: Academic Title: Specialty: Associate Professor / MD Programme Director Cancer Biology constantinou.co@unic.ac.cy Phone: B. EMPLOYMENT HISTORY (From current to oldest) including your affiliation with the University of Nicosia Medical School From To Position/Title Employer 2/2015 Current MD Programme Director/ Associate Professor in Cancer Biology (Full-Time) 9/2014 1/2015 MD Programme Coordinator/ Associate Professor in Cancer Biology (Full-Time) 9/2013 8/2014 Academic Lead for SSCs (Self Selected Components) and Projects for the MBBS Programme/ Associate Professor in Cancer Biology 11/2012 8/2013 Associate Professor, Academic Lead for T year (Second Year) of MBBS4 Programme, Academic Lead for SSCs (Self Selected Components) and Projects,

2 Module Convenor for Life Protection for the MBBS Programme 9/ /2012 Director of & Innovation Office, Associate Professor in the Department of Life and Health Sciences, Module Convenor/ SSC Academic Lead and Chief Examiner 2/2011 9/2011 Associate Director of & Innovation Office, Associate Professor in the Department of Life and Health Sciences, Module Convenor/ SSC Academic Lead and Chief Examiner for the MBBS Programme 9/2010 8/2011 Associate Director of Office, Associate Professor in the Department of Life and Health Sciences Department of Life and Health Sciences at the University of Nicosia and Department of Life and Health Sciences at the University of Nicosia and University of Nicosia and Department of Life and Health Sciences at the University of Nicosia and 1/2010 6/2010 Visiting Lecturer Frederick University 1/2009 2/2010 and Development Manager Yasoo Health Ltd., 2/ /2009 Special Scientist University of Cyprus, 9/ /2008 and Development Yasoo Health Ltd.,

3 Project Manager 8/2005 7/2006 Post-doctoral research fellow in the Division of Basic Medical Sciences St. George s, University of London, London, UK C. EDUCATIONAL BACKGROUND 1. University or equivalent From To Name of University/ Academic Institution 1/2011 2/2012 Postgraduate Certificate in Learning and Teaching in Higher Education Degree Obtained University of Hertfordshire, Hertfordshire, UK 11/2001 7/2005 PhD in Biochemistry St. George s, University of London (previously known as St. George s Hospital Medical School), London, UK 9/1997 9/1998 MSc in General and Medical Microbiology with Distinction 8/1993 1/1997 Bachelor s Degree in Biological Sciences with Distinction in all subjects (concentration in Microbiology) University College London, University of London, UK Cornell University, College of Arts and Sciences, Ithaca, NY, USA 9/1987 6/1993 American Academy Diploma with Highest Honours American Academy,

4 D. RESEARCH PROGRAMMES (e.g Academic Lead/Group Member, er, Assistant er) Up to 10 most important and 5 of the most recent From To 1 12/2009 9/2010 Project: Development of a novel Programme/Title Sponsor Role chemotherapeutic agent for the treatment of prostate cancer. Program: Έρευνα για Επιχειρήσεις, Δράση Εφαρμοσμένη Έρευνα για Επιχειρήσεις. Program code: ΕΠΙΧΕΙΡΗΣΕΙΣ/ΕΦΑΡΜ/0308/12 Foundation Coordinator 2 12/2006 6/2009 Project: Evaluation of the chemoprotective and anti-cancer activities of natural and synthetic antioxidant compounds. Program: Ένταξη, Ενίσχυση και Κινητικότητα νέων ερευνητών-πενεκ, Δράση Κινητικότητα. Program code: KINHT 0506/06. Τhe application received the highest score (9.6/10) 3 12/ /2008 Project: Development of a novel nutraceutical product for the adjuvant treatment of inflammatory bowel disease. Program: EUREKA. Program code: EUREKA/0506/05 Foundation. Foundation New scientist Scientist, grant management 4 12/ /2008 Project: Development of a novel Scientist, grant nutraceutical for the prevention and management of type 2 diabetes and its complications. Foundation

5 Program code: AKGEN/0506/04. E. AWARDS/INTERNATIONAL DISTINCTIONS Date Award/Distinction Awarding Body Funding for Post-doctoral research The Wellcome Trust (Value In People Award), UK Scholarship The Overseas Awards Scheme (ORS), UK Scholarship The Cancer Prevention Trust, UK Scholarship The A. G. Leventis Foundation, Cyprus Fulbright Scholarship. Fulbright Scholarship Programme Dean s List Cornell University F. PUBLICATIONS- Up to 10 most important and 5 of the most recent Date Published Publication Neophytou C.M., Constantinou, C., Papageorgis, P., and Constantinou, C. I. (2014). D-Alpha-tocopheryl polyethylene glycol succinate (TPGS) induces cell cycle arrest and apoptosis selectively in Survivin-overexpressing breast cancer cells. Biochemical Pharmacology 89, Nicolaou, K.A., Liapis, V., Evdokiou, A., Constantinou, C., Magiatis, P., Skaltsounis, A. L., Koumas, L., Costeas, P.A., and Constantinou, A.I. (2012). Induction of discrete apoptotic pathways by bromo-substituted indirubin derivatives in invasive breast cancer cells. Biochemical and Biophysical Communications 425(1),

6 Constantinou, C. VITAMIN E: Future directions for understanding the anti-cancer capacity of an important micronutrient. Short communication in book Vitamin E: Nutrition, Side Effects and Supplements. Nova Publishers pp (2012) Constantinou, C., Neophytou, C., Hyatt, J.A., Papas, K.A., Hadjivassiliou, V., and Constantinou, A.I. (2012). Induction of caspase dependent and independent DNA damage and dominant caspase-independent programmed cell death by vitamin E isoforms and synthetic derivatives in prostate cancer cell lines. Nutrition and Cancer 64(1), Constantinou, C., Ηyatt, J., Vraka, P., Hadjivassiliou, V., Papas, K.A., Neophytou, C., and Constantinou, A.I. (2009). Regulation of caspase-independent cell death by vitamin E natural homologs and synthetic derivatives. Nutrition and Cancer 61, Constantinou, C., Papas, G., and Constantinou, A.I. (2009). Caspase independent pathways of programmed cell death: the unraveling of key targets of cancer therapy? Current Cancer Drug Targets 9(6), Constantinou, C., Papas, A., and Constantinou, A.I. (2008). Vitamin E and cancer: an insight into the anti-cancer activities of vitamin E family members. International Journal of Cancer 123, Constantinou, C., Elia, A., and Clemens, M.J. (2008). Activation of p53 stimulates proteasome-dependent truncation of the eif4e binding protein 4E-BP1. Biology of the Cell 100, Constantinou, C., and Clemens, M.J. (2007). Regulation of eif4gi and 4E-BP1 during recovery of protein synthesis from inhibition by p53. Differentiation 14, Cell Death and Constantinou, C., and Clemens, M J. (2005). Regulation of the phosphorylation and integrity of protein synthesis initiation factor eif4gi and the translational repressor 4E-BP1 by p53. Oncogene 24,