Bio 100 Guide 08.
|
|
- Amice Wood
- 5 years ago
- Views:
Transcription
1 Bio 100 Guide 08
2
3
4
5
6
7 Common Chromosomal Abnormalities * Turner syndrome results from a single X chromosome (45, X or 45, X0). * Klinefelter syndrome, the most common male chromosomal disease, otherwise known as 47, XXY is caused by an extra X on sex chromosome 23. * Edwards syndrome is caused by trisomy (three copies) of chromosome 18. * Down syndrome, a common chromosomal disease, is caused by trisomy of chromosome 21. * Patau syndrome is caused by trisomy of chromosome 13.
8 Molecular & Genetic basis of Cystic Fibrosis CF Protein creates a Cl -- permeable channel in the outer cell membrane. Persons with Cystic Fibrosis (OMIM219700) are typically homozygous for an allele with a 3bp deletion (508) that removes a phenylalanine residue from a position near a nucleotide binding domain. CF proteins with this defect are destroyed by the cell. In the absence of Cl -- channels, the Cl / Na balance of the cell is disrupted. This leads to an accumulation of mucous in the lungs, a condition which is can be fatal.
9 Turner syndrome or Ullrich-Turner syndrome encompasses several chromosomal abnormalities, of which monosomy X is the most common. It occurs in 1 out of every 2500 female births.[1] Instead of the normal XX sex chromosomes for a female, only one X chromosome is present and fully functional. A normal female karyotype is labeled 46,XX; individuals with Turner syndrome are 45,X (also labeled 45,X0 or less commonly X(,)) though other genetic variants occur. In Turner syndrome, female sexual characteristics are present but generally underdeveloped.
10 Common Chromosomal Abnormalities Some disorders arise from loss of just a piece of one chromosome, including * Cri du chat (cry of the cat), from a truncated short arm on chromosome 5. The name comes from the babies' distinctive cry, caused by abnormal formation of the larynx.
11 Chromosomal abnormalities can also occur in cancerous cells of an otherwise genetically normal individual; one well-documented example is the Philadelphia chromosome, a translocation mutation commonly associated with chronic myelogenous leukemia and less often with acute lymphoblastic leukemia.
12 Making a Personal Pedigree For each relative, try to write down as many of these items as possible: Age or date of birth (and, for all family members who have passed on, age at death and cause of death). When the information is unavailable, write down your best guess (for example, 40 s ).
13 Cancer Heart disease Gather information on Medical Problems Diabetes Asthma Mental illness High blood pressure Stroke Kidney disease Alcoholism Others
14 Note the ages at which the conditions occurred. Did Uncle Pete have his heart attack at age 42 or age 88? Did your mother develop diabetes in childhood or as an adult? Birth defects such as spina bifida, cleft lip, heart defects, others. Learning problems, mental retardation. Vision loss/hearing loss at a young age (remember to record the age it began).
15 For family members with known medical problems, jot down if they smoked, their diet and exercise habits, and if they were overweight. (for example, you could note that your brother John, who had a heart attack at age 40, weighs 300 lbs and smokes 2 packs a day).
16
17
18
19 Although all cancer is caused by mutations in specific types of genes (oncogenes, tumor suppressor genes, and DNA repair genes), not all of these mutations are inherited. Only about 1-2% of cancers are hereditary and cluster in families with a strong shared susceptibility. Most people have sporadic cancer without a positive family history of the disease. In the vast majority of cancer cases there is no apparent familial clustering. For most common cancers, an individual with a first-degree relative with the disease will have approximately twice the risk of the general population.
20 PseudoIsochromatic Plate Ishihara Compatible (PIPIC) Color Vision Enter the number you see
21 PseudoIsochromatic Plate Ishihara Compatible (PIPIC) Color Vision Enter the number you see
22 Cystic Fibrosis Carrier Rates Race/Ethnicity Chance of being a carrier Chance both partners are carriers European Caucasian Ashkenazi Jewish 1 in 29 1 in 841 Hispanic American 1 in 46 1 in 2,116 African American 1 in 65 1 in 4,225 Asian American 1 in 90 1 in 8,100
23
24
25
26 The defect is found in 1 in 20,000 births, a general screening program (PKU Test) has been mandated in many states and is routinely made several days after the birth of an infant. Phenylketonuria (PKU)
27 The End
Bio 105 Guide 08.
Bio 105 Guide 08 http://images.andrewsmcmeel.com/media/3820/medium.jpg The chromosomes present in 1 cell nucleus! http://www.unm.edu/~vscience/images/hela%20karyotype%203%20(1000x).jpg karyotype http://www.ucl.ac.uk/~ucbhjow/medicine/images/human_karyotype.gif
More informationGenetic Disorders. PART ONE: Detecting Genetic Disorders. Amniocentesis Chorionic villus sampling Karyotype Triple Screen Blood Test
Genetic Disorders PART ONE: Detecting Genetic Disorders Amniocentesis Chorionic villus sampling Karyotype Triple Screen Blood Test Amniocentesis A technique for determining genetic abnormalities in a fetus
More informationHuman Genetic Mutations
Human Genetic Mutations 2 Main Types of Mutations 1.) Chromosomal Mutations 2.) Gene Mutations What are chromosomes? Humans have 23 pairs of chromosomes, with one chromosome from each parent. The chromosomes
More informationChromosomal Abnormalities and Karyotypes Creating a Karyotype
Chromosomal Abnormalities and Karyotypes Creating a Karyotype The Normal Human Karyotype The normal human karyotype is composed of SEVEN groups of chromosomes A G plus the sex chromosomes X and Y. The
More informationMULTIPLE CHOICE QUESTIONS
SHORT ANSWER QUESTIONS-Please type your awesome answers on a separate sheet of paper. 1. What is an X-linked inheritance pattern? Use a specific example to explain the role of the father and mother in
More informationHuman Genetic Disorders
Human Genetic Disorders HOMOLOGOUS CHROMOSOMES Human somatic cells have 23 pairs of homologous chromosomes 23 are inherited from the mother and 23 from the father HOMOLOGOUS CHROMOSOMES Autosomes o Are
More informationMutations Quick Questions and Notes (#1) QQ#1: What do you know about mutations?
Mutations Quick Questions and Notes (#1) QQ#1: What do you know about mutations? mutation basics Definition: a change in the genetic material of a cell Note: not all mutations are bad Can occur in 2 types
More informationGene Expression and Mutation
Gene Expression and Mutation GENE EXPRESSION: There are hormonal and environmental factors that may cause the expression of some genetic information. Some examples are: 1. The two- colour pattern of some
More informationUnit 3: DNA and Genetics Module 9: Human Genetics
Unit 3: DNA and Genetics Module 9: Human Genetics NC Essential Standard: 3.2 Understand how the environment, and /or the interaction of alleles, influences the expression of genetic traits. 3.3.3 Evaluate
More informationHths 2231 Laboratory 3 Genetics
Watch Movie: Cystic Fibrosis Answer the movie questions on the worksheet. Complete activities 1-5 Activity #1: Under Lab 3 Click on activity 1 Click on Tour of the Basics Do all 6 What is exercises Activity
More informationClick on Karyotyping under human biology and read the Introduction page: 1. What causes a dark band on the chromosome?
Karyotyping Activity Name: In this activity, you will use a computer model to look at chromosomes and prepare a karyotype. You will diagnose patients for abnormalities and learn the correct notation for
More informationGenetic Diseases. SCPA202: Basic Pathology
Genetic Diseases SCPA202: Basic Pathology Amornrat N. Jensen, Ph.D. Department of Pathobiology School of Science, Mahidol University amornrat.nar@mahidol.ac.th Genetic disease An illness caused by abnormalities
More informationKaryotype Lab. Patient James a 28 year old male who is trying to determine why he he can t have children.
Name: Karyotype Lab Block: Objective: Students will interpret karyotypes to determine the gender of individuals and whether they have chromosomal abnormalities. Problem: The genetics lab has mixed up the
More informationGenetics. the of an organism. The traits of that organism can then be passed on to, on
Genetics DNA contains the genetic code for the production of. A gene is a segment of DNA, which consists of enough bases to code for many different proteins. The specific proteins produced by a gene determine
More informationPedigree Analysis. Genetic disorders. Dominant inheritance. Recessive inheritance. Autosomal vs. sex-linked traits. X-linked recessive inheritance
Genetic disorders 4.2 Errors During Meiosis 5.3 Following Patterns of Human nheritance Pedigree Analysis 2005 Lee Bardwell Autosomal vs. sex-linked traits Autosomal traits are caused by genes on autosomes
More informationChapter 11 Gene Expression
Chapter 11 Gene Expression 11-1 Control of Gene Expression Gene Expression- the activation of a gene to form a protein -a gene is on or expressed when it is transcribed. -cells do not always need to produce
More informationCh 7 Extending Mendelian Genetics
Ch 7 Extending Mendelian Genetics Studying Human Genetics A pedigree is a chart for tracing genes in a family. Used to determine the chances of offspring having a certain genetic disorder. Karyotype=picture
More informationLab Activity 36. Principles of Heredity. Portland Community College BI 233
Lab Activity 36 Principles of Heredity Portland Community College BI 233 Terminology of Chromosomes Homologous chromosomes: A pair, of which you get one from mom, and one from dad. Example: the pair of
More informationUnit 3: DNA and Genetics Module 9: Human Genetics
Unit 3: DNA and Genetics Module 9: Human Genetics NC Essential Standard: 3.2.3 Explain how the environment can influence expression of genetic traits 3.3.3 Evaluate ethical issues surrounding the use of
More informationLesson Overview Human Chromosomes
Lesson Overview 14.1 Human Chromosomes Human Genome To find what makes us uniquely human, we have to explore the human genome, which is the full set of genetic information carried in our DNA. This DNA
More informationGenetic Diseases. SCPA202: Basic Pathology
Genetic Diseases SCPA202: Basic Pathology Amornrat N. Jensen, Ph.D. Department of Pathobiology School of Science, Mahidol University amornrat.nar@mahidol.ac.th Genetic disease An illness caused by abnormalities
More informationGenetics. by their offspring. The study of the inheritance of traits is called.
Genetics DNA contains the genetic code for the production of. A gene is a part of DNA, which has enough bases to make for many different proteins. These specific proteins made by a gene decide the of an
More informationLecture 17: Human Genetics. I. Types of Genetic Disorders. A. Single gene disorders
Lecture 17: Human Genetics I. Types of Genetic Disorders A. Single gene disorders B. Multifactorial traits 1. Mutant alleles at several loci acting in concert C. Chromosomal abnormalities 1. Physical changes
More informationChromosomal Mutations
Notes 2/17 Chromosomal Mutations A chromosome mutation is an unpredictable change that occurs in a chromosome. These changes are most often brought on by problems that occur during meiosis or by mutagens
More informationNOTES: : HUMAN HEREDITY
NOTES: 14.1-14.2: HUMAN HEREDITY Human Genes: The human genome is the complete set of genetic information -it determines characteristics such as eye color and how proteins function within cells Recessive
More informationChromosome Abnormalities
Chromosome Abnormalities Chromosomal abnormalities vs. molecular mutations Simply a matter of size Chromosomal abnormalities are big errors Two types of abnormalities 1. Constitutional problem present
More informationBIO113 Exam 2 Ch 4, 10, 13
BIO113 Exam 2 Ch 4, 10, 13 See course outline for specific reading assignments Study notes and focus on terms and concepts The images in the textbook are useful CELLS (pg. 37) The basic unit of life living
More informationChapter 15 Notes 15.1: Mendelian inheritance chromosome theory of inheritance wild type 15.2: Sex-linked genes
Chapter 15 Notes The Chromosomal Basis of Inheritance Mendel s hereditary factors were genes, though this wasn t known at the time Now we know that genes are located on The location of a particular gene
More informationUnit 3 Chapter 16 Genetics & Heredity. Biology 3201
Unit 3 Chapter 16 Genetics & Heredity Biology 3201 Intro to Genetics For centuries, people have known that certain physical characteristics are passed from one generation to the next. Using this knowledge,
More informationUNIT IX: GENETIC DISORDERS
UNIT IX: GENETIC DISORDERS Younas Masih Lecturer New Life College Of Nursing Karachi 3/4/2016 1 Objectives By the end of this session the Learners will be able to, 1. Know the basic terms related genetics
More informationGenetic Carrier Testing Cystic Fibrosis (CF) Spinal Muscular Atrophy (SMA) Fragile X Syndrome
Genetic Carrier Testing Cystic Fibrosis (CF) Spinal Muscular Atrophy (SMA) Fragile X Syndrome It s about knowing. Prenatal testing is not about telling you what s wrong, it s knowing that everything is
More informationIN-VITRO FERTILIZATION WITH DONATED OOCYTES COMPREHENSIVE HISTORY OF RECIPIENT COUPLE (HUSBAND)
Personal History Name Date of Birth Home Address Home Phone Work Phone Type of Employment Social Security # Medical Insurance Marital Status Religion Highest education degree (high school, college, graduate
More informationGenes are found on Chromosomes! Genes are found on Chromosomes! I. Types of Mutations
Genes are found on Chromosomes! genes and chromosomes are made up of DNA, which is the genetic material for all life on earth genes are found on a specific region on a chromosome; called a locus (loci)
More informationSection Objectives: Pedigrees illustrate inheritance. Pedigrees illustrate inheritance
What You ll Learn You will compare the inheritance of recessive and dominant traits in humans. You will analyze the inheritance patterns of traits with incomplete dominance and codominance. You will determine
More informationLesson Overview. Human Genetic Disorders. Lesson Overview Human Genetic Disorders
Lesson Overview 14.2 Human Genetic Disorders THINK ABOUT IT Have you ever heard the expression It runs in the family? Relatives or friends might have said that about your smile or the shape of your ears,
More informationThe Chromosomal Basis of Inheritance
The Chromosomal Basis of Inheritance Factors and Genes Mendel s model of inheritance was based on the idea of factors that were independently assorted and segregated into gametes We now know that these
More informationGenetics in Primary Care Curriculum Statement 6. Dr Dave Harniess PCME Stockport
Genetics in Primary Care Curriculum Statement 6 Dr Dave Harniess PCME Stockport Learning Objectives Understanding of genetic component of disease Screening for genetic conditions and risk assessment in
More information40 Bell Work Week 8 5/12 41 Genetic Notes 5/12 42 Bill Nye Video & Questions 5/12
40 Bell Work Week 8 5/12 41 Genetic Notes 5/12 42 Bill Nye Video & Questions 5/12 1. I am available after school on Wed. and Thurs. this week. 2. Quiz Friday over genetic material 3. Last day to turn in
More informationIntroduction to Genetics
Introduction to Genetics Table of contents Chromosome DNA Protein synthesis Mutation Genetic disorder Relationship between genes and cancer Genetic testing Technical concern 2 All living organisms consist
More informationLesson Overview. Human Genetic Disorders. Lesson Overview Human Genetic Disorders
Lesson Overview 14.2 Human Genetic Disorders From Molecule to Phenotype There is a direct connection between molecule and trait, and between genotype and phenotype. In other words, there is a molecular
More informationTopic 4 Year 10 Biology
Topic 4 Year 10 Biology TOPIC 4 CHROMOSOMES & CELL DIVISION Things to cover: 1. Chromosomes 2. Karyotypes inc. chromosomal disorders 3. Cell division inc. mitosis, meiosis & fertilisation Work to do: 1.
More informationCONTROL OF CELL DIVISION
CONTROL OF CELL DIVISION Regulation of cell division is necessary to determine when and how cells should divide. Types of Regulators: Internal regulators: Cyclins proteins that regulate the timing of the
More informationCh. 15 The Chromosomal Basis of Inheritance
Ch. 15 The Chromosomal Basis of Inheritance Nov 12 12:58 PM 1 Essential Question: Are chromosomes the basis of inheritance? Nov 12 1:00 PM 2 1902 Walter S. Sutton, Theodor Boveri, et al Chromosome Theory
More information14 2 Human Chromosomes
14-2 Human Chromosomes 1 of 25 Sex-Linked Genes Sex-Linked Genes The X chromosome and the Y chromosomes determine sex. Genes located on these chromosomes are called sex-linked genes. More than 100 sex-linked
More informationThe Chromosomal Basis of Inheritance
LECTURE PRESENTATIONS For CAMPBELL BIOLOGY, NINTH EDITION Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson Chapter 15 The Chromosomal Basis of Inheritance
More informationChromosomes and Gene Expression. Exceptions to the Rule other than sex linked traits
Chromosomes and Gene Expression Exceptions to the Rule other than sex linked traits Chromosome Inactivation If girls have two X chromosomes, do they produce more proteins than boys with only one X chromosome???
More informationHuman Genetic Disorders. Lesson Overview. Lesson Overview Human Genetic Disorders
Lesson Overview 14.2 Human Genetic Disorders THINK ABOUT IT Have you ever heard the expression It runs in the family? Relatives or friends might have said that about your smile or the shape of your ears,
More informationPrepare a karyotype of these chromosomes. A karyotype is a pattern or picture of chromosomes from one cell grouped into pairs and organized by size.
MR. POMERANTZ Page 1 of 7 In this activity, you will create a karyotype from a page of mixed chromosomes. Karyotypes are created by matching homologous pairs and numbering them from largest to smallest.
More informationSex Determination. Male = XY. Female = XX. 23 pairs of chromosomes (22 autosomes/body chromosomes, 1 sex)
Sex Determination Male = XY Female = XX 23 pairs of chromosomes (22 autosomes/body chromosomes, 1 sex) X chromosome----->large, rod shaped Y chromosome-----> smaller Mating of male & female XY x XX X Y
More informationChapter 15 - Chromosomal Basis of Inheritance CHROMOSOMAL THEORY OF INHERITANCE
Chapter 15 - Chromosomal Basis of Inheritance CHROMOSOMAL THEORY OF INHERITANCE Early 1900 s cytology and genetics merge ~ parallels between chromosome behavior and Mendel s factors MENDEL s hereditary
More information-19. -Mousa Salah. -Shahd Alqudah. -Dr Belal
التزام -19 -Mousa Salah -Shahd Alqudah -Dr Belal 1 P a g e In the previous lecture we talked about the numerical chromosomal abnormalities, they are either autosomal or sex, and we said that the chromosomal
More informationHuman Heredity: The genetic transmission of characteristics from parent to offspring.
Human Heredity: The genetic transmission of characteristics from parent to offspring. Karyotype : picture of the actual chromosomes arranged in pairs, paired and arranged from largest to smallest. Human
More informationSection Chapter 14. Go to Section:
Section 12-3 Chapter 14 Go to Section: Content Objectives Write these Down! I will be able to identify: The origin of genetic differences among organisms. The possible kinds of different mutations. The
More informationLesson Overview. Human Chromosomes. Lesson Overview. Human Chromosomes
Lesson Overview Karyotypes A genome is the full set of genetic information that an organism carries in its DNA. A study of any genome starts with chromosomes, the bundles of DNA and protein found in the
More informationChromosome Mutations
Chromosome Mutations Variation in Chromosome Number Euploidy: having full sets of chromosomes Haploid Diploid Triploid Aneuploidy: having anything other than full sets of chromosomes Monosomy Trisomy Variation
More informationChromosomes and Human Inheritance. Chapter 11
Chromosomes and Human Inheritance Chapter 11 11.1 Human Chromosomes Human body cells have 23 pairs of homologous chromosomes 22 pairs of autosomes 1 pair of sex chromosomes Autosomes and Sex Chromosomes
More informationGenetics, Mendel and Units of Heredity
Genetics, Mendel and Units of Heredity ¾ Austrian monk and naturalist. ¾ Conducted research in Brno, Czech Republic from 1856-1863 ¾ Curious about how traits were passed from parents to offspring. Gregor
More informationThe Living Environment Unit 3 Genetics Unit 11 Complex Inheritance and Human Heredity-class key. Name: Class key. Period:
Name: Class key Period: Chapter 11 assignments Pages/Sections Date Assigned Date Due Topic: Recessive Genetic Disorders Objective: Describe some recessive human genetic disorders. _recessive_ alleles are
More informationGenetics 1. Down s syndrome is caused by an extra copy of cshromosome no 21. What percentage of
Genetics 1. Down s syndrome is caused by an extra copy of cshromosome no 21. What percentage of offspring produced by an affected mother and a normal father would be affected by this disorder? (2003) 1)
More informationGenomics and Genetics in Healthcare. By Mary Knutson, RN, MSN
Genomics and Genetics in Healthcare By Mary Knutson, RN, MSN Clinical Objectives Understand the importance of genomics to provide effective nursing care Integrate genetic knowledge and skills into nursing
More informationChapter 28 Modern Mendelian Genetics
Chapter 28 Modern Mendelian Genetics (I) Gene-Chromosome Theory Genes exist in a linear fashion on chromosomes Two genes associated with a specific characteristic are known as alleles and are located on
More informationCell Division and Inheritance
Cell Division and Inheritance Continuing life relies on reproduction Individual organism replacing dead or damaged cells Species making more of same species Reproduction Cells divide, grow, divide again
More informationThe Chromosomal Basis Of Inheritance
The Chromosomal Basis Of Inheritance Chapter 15 Objectives Explain the chromosomal theory of inheritance and its discovery. Explain why sex-linked diseases are more common in human males than females.
More informationMutations. New inherited traits, or mutations, may appear in a strain of plant or animal.
Genetic Mutations Mutations New inherited traits, or mutations, may appear in a strain of plant or animal. The first individual showing the new trait is called a mutant. 2 Types of Mutations Chromosomal
More informationThe Chromosomal Basis of Inheritance
Chapter 15 The Chromosomal Basis of Inheritance PowerPoint Lecture Presentations for Biology Eighth Edition Neil Campbell and Jane Reece Lectures by Chris Romero, updated by Erin Barley with contributions
More informationShould Universal Carrier Screening be Universal?
Should Universal Carrier Screening be Universal? Disclosures Research funding from Natera Mary E Norton MD University of California, San Francisco Antepartum and Intrapartum Management June 15, 2017 Burden
More informationTesting for Genetic Disorders that Cause Brain Damage
STO-132 Testing for Genetic Disorders that Cause Brain Damage Part 1: Newborn Screening Tests Matt is watching his twins, Anna and Cody, in the newborn nursery. The nurse pokes the babies heels, collects
More informationA. Definitions... CD-157. B. General Information... CD-158
CD Part 10 Multiple Body System Disorders A. Definitions... CD-157 B. General Information... CD-158 C. Specific Listings and Residual Functional Capacity... CD-158 1. Listing 10.06: Non-Mosaic Down Syndrome
More informationFigure 1: Transmission of Wing Shape & Body Color Alleles: F0 Mating. Figure 1.1: Transmission of Wing Shape & Body Color Alleles: Expected F1 Outcome
I. Chromosomal Theory of Inheritance As early cytologists worked out the mechanism of cell division in the late 1800 s, they began to notice similarities in the behavior of BOTH chromosomes & Mendel s
More informationNormal enzyme makes melanin (dark pigment in skin and hair) Defective enzyme does not make melanin
Genetics Supplement (These supplementary modules, a Genetics Student Handout, and Teacher Preparation Notes with suggestions for implementation are available at http://serendip.brynmawr.edu/sci_edu/waldron/#genetics.
More informationTwo copies of each autosomal gene affect phenotype.
UNIT 3 GENETICS LESSON #34: Chromosomes and Phenotype Objective: Explain how the chromosomes on which genes are located can affect the expression of traits. Take a moment to look at the variety of treats
More informationCELLS. Some human cells
CELLS the basic unit of life living things are composed of at least one cell cells metabolize (obtain energy, use energy, make waste) cells can reproduce cells sense and respond to the environment red
More informationHuman Genetics Notes:
Human Genetics Notes: Human Chromosomes Cell biologists analyze chromosomes by looking at. Cells are during mitosis. Scientists then cut out the chromosomes from the and group them together in pairs. A
More informationUNIT IV. Chapter 14 The Human Genome
UNIT IV Chapter 14 The Human Genome UNIT 2: GENETICS Chapter 7: Extending Medelian Genetics I. Chromosomes and Phenotype (7.1) A. Two copies of each autosomal gene affect phenotype 1. Most human traits
More informationMutations. A2 Biology For WJEC
12. Mutation is a change in the amount, arrangement or structure in the DNA of an organism. 13. There are two types of mutations, chromosome mutations and gene mutations. Mutations A2 Biology For WJEC
More informationChromosome Disease. The general features in autosome abnormalities are a triad of growth retardation, mental
Medical Genetics Chapter4 Chromosome Disease Chromosome Disease Clinical feature The general features in autosome abnormalities are a triad of growth retardation, mental retardation, and specific somatic
More information8/31/2017. Biology 102. Lecture 10: Chromosomes and Sex Inheritance. Independent Assortment. Independent Assortment. Independent Assortment
Biology 102 Lecture 10: Chromosomes and Sex Inheritance All of our examples of inheritance patterns have focused on single genes Humans have 25,000 genes! Genes on the same chromosome are inherited together
More informationPatterns of Inheritance
Patterns of Inheritance Some diseases are caused by changes in genes (mutations). Remember, there are always two copies of each gene in a person, but changes in the genes can cause some genetic diseases.
More informationChapter 11. Chromosomes and Human Inheritance
Chapter 11 Chromosomes and Human Inheritance Human Chromosomes Human body cells have 23 pairs of homologous chromosomes 22 pairs of autosomes 1 pair of sex chromosomes Autosomesand Sex Chromosomes Paired
More informationGenetic Disorders. n A genetic disorder is an abnormality
+ GENETIC DISORDERS + Genetic Disorders n A genetic disorder is an abnormality in an individual's DNA. Abnormalities can range from a small mutation in a single gene to the addition or subtraction of an
More informationHuman inherited diseases
Human inherited diseases A genetic disorder that is caused by abnormality in an individual's DNA. Abnormalities can range from small mutation in a single gene to the addition or subtraction of a whole
More informationGenetic Disorders. Students must provide an explanation for all problems. Students must have parent signature prior to submission.
Name: Date: Students must provide an explanation for all problems. Students must have parent signature prior to submission. 1. A human hereditary disorder that may result in mental retardation is 1. A.
More informationMEIOSIS: Genetic Variation / Mistakes in Meiosis. (Sections 11-3,11-4;)
MEIOSIS: Genetic Variation / Mistakes in Meiosis (Sections 11-3,11-4;) RECALL: Mitosis and Meiosis differ in several key ways: MITOSIS: MEIOSIS: 1 round of cell division 2 rounds of cell division Produces
More informationReview Packet for Genetics and Meiosis
Name: Date: Block: 1 Review Packet for Genetics and Meiosis Directions: Answer the questions and where indicated, draw a Punnett square and show all work! 1. Who was Gregor Mendel? Where did he live and
More informationClassifications of genetic disorders disorders
Classifications of genetic disorders Dr. Liqaa M. Sharifi Human diseases in general can roughly be classified in to: 1-Those that are genetically determined. 2-Those that are almost entirely environmentally
More informationGenes and Inheritance (11-12)
Genes and Inheritance (11-12) You are a unique combination of your two parents We all have two copies of each gene (one maternal and one paternal) Gametes produced via meiosis contain only one copy of
More information10/26/2015. ssyy, ssyy
Biology 102 Lecture 10: Chromosomes and Sex Inheritance All of our examples of inheritance patterns have focused on single genes Humans have 25,000 genes! Genes on the same chromosome are inherited together
More informationHonors Biology Review Sheet to Chapter 9 Test
Honors Biology Review Sheet to Chapter 9 Test Name Per 1. Label the following flower: sepal, petal, anther, filament, style, ovary, stigma Draw in ovules and label. Color the female structure red and the
More informationChapter 11 Patterns of Chromosomal Inheritance
Inheritance of Chromosomes How many chromosomes did our parents gametes contain when we were conceived? 23, 22 autosomes, 1 sex chromosome Autosomes are identical in both male & female offspring For the
More informationTHE KING AND THE SCRATCHED DIAMOND
BIRTH DEFECTS 1 THE KING AND THE SCRATCHED DIAMOND Once there was a king who had a beautiful, large pure diamond. There was no other diamond like it in the world. One day, it became deeply scratched. The
More informationPre-AP Biology Unit 7 Genetics Review Outline
Unit 7 Genetics Review Outline Pre-AP Biology 2017-2018 LT 1 - I can explain the relationships among alleles, genes, chromosomes, genotypes, and phenotypes. This target covers application of the vocabulary
More information2. Circle the genotypes in the table that are homozygous. Explain how the two different homozygous genotypes result in different phenotypes.
Genetics Supplement (These supplementary modules, a Genetics Student Handout, and Teacher Preparation Notes with background information are available at http://serendip.brynmawr.edu/sci_edu/waldron/#genetics.
More informationCYTOGENETICS Dr. Mary Ann Perle
CYTOGENETICS Dr. Mary Ann Perle I) Mitosis and metaphase chromosomes A) Chromosomes are most fully condensed and clearly distinguishable during mitosis. B) Mitosis (M phase) takes 1 to 2 hrs and is divided
More informationThe Chromosomal Basis of Inheritance
Chapter 15 The Chromosomal Basis of Inheritance PowerPoint Lectures for Biology, Seventh Edition Neil Campbell and Jane Reece Lectures by Chris Romero Overview: Locating Genes on Chromosomes A century
More informationPreconception/prenatal family history questionnaire
1 of 5 Today s date: Person completing questionnaire: Patient Partner/spouse Name Date of birth Occupation Marital status (married, divorced, widowed, single) Last grade completed Height Weight Adopted
More informationSEX-LINKED INHERITANCE. Dr Rasime Kalkan
SEX-LINKED INHERITANCE Dr Rasime Kalkan Human Karyotype Picture of Human Chromosomes 22 Autosomes and 2 Sex Chromosomes Autosomal vs. Sex-Linked Traits can be either: Autosomal: traits (genes) are located
More informationWhat is the inheritance pattern (e.g., autosomal, sex-linked, dominant, recessive, etc.)?
Module I: Introduction to the disease Give a brief introduction to the disease, considering the following: the symptoms that define the syndrome, the range of phenotypes exhibited by individuals with the
More information- Aya Alomoush. - Talal Al-Zabin. - Belal Azab. 1 P a g e
24 - Aya Alomoush - Talal Al-Zabin - Belal Azab 1 P a g e 1) Features of autosomal dominant inheritance: A) Vertical transmission: direct transmission from grandparent to parent to child without skipping
More informationRecombina*on of Linked Genes: Crossing Over. discovered that genes can be linked. the linkage was incomplete
Recombina*on of Linked Genes: Crossing Over Fig. 15-10 Testcross parents Gray body, normal wings (F 1 dihybrid) Black body, vestigial wings (double mutant) Morgan discovered that genes can be linked the
More informationKlinefelter syndrome ( 47, XXY )
Sex Chromosome Abnormalities, Sex Chromosome Aneuploidy It has been estimated that, overall, approximately one in 400 infants have some form of sex chromosome aneuploidy. A thorough discussion of sex chromosomes
More information