ABBREVIATIONS BOD. Ac-DEVD-AFC Ac-DEVD-CHO AcNPV A1F AP

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1 ABBREVIATIONS Ac-DEVD-AFC Ac-DEVD-CHO AcNPV A1F AP Apaf-1 ATF 4 ATM ATP Bad Bak Bax BCIP Bcl-2 BH Bid BIM Bip BIR BOD BOK BOO CAD c-amp CARD CAT Ced : N-acetyl-Asp-Glu-Val-Asp-amino-4-trifiuoromethyl coumarin : N-acetyi-Asp-Glu-Val-Asp-aldehyde : Autographa californica nuclear polyhedrosis virus : Apoptosis inducing factor : Alkaline phosphatase : Apoptosis protein activating factor : Activated transcription factor : Ataxia telangiectasia mutated protein : Adenosine 5' tri phosphate : Bcl-2/Bcl-XL associated death promoter : Bcl-2 homologous antagonist killer : Bcl-2 associated X-protein : 5-bromo-4-chloro-3-indoyl-phoshphate : B-cell CLL : Bcl-2 homology domain : BH3 interacting death domain agonist : Bcl-2 interacting mediator : Immunoglobulin heavy chain binding protein : Baculovirus IAP repeat : Bcl-2 related ovarian death agonist : Bcl-2 related ovarian killer : Bcl-2 homologue of ovary : Caspase activated DNase : cyclic- adenosine mono phosphate : Caspase activation recruitment domain : Chloramphenicol acetyl transferase : Cell death iii

2 Met mg MOI NACa NAIP NBT NF-kB NP Omi OP1AP PABP PAGE PAK2 PARP PDI PERK PKc5 PKR PP2A PUMA ROCK Rpr S51A S5ID SDS Sf9 Smac SRP TEMED Tg : Methionine : milligram : Multiplicity of infection : Nascent associated complex a : Nucleotide binding apoptosis inhibitor protein : Nitro Blue Tetrazolium : Nuclear factor-kappa B : Nucleo capsid protein : Outer mitochondrial IAP binding protein : Orgyia pseuditsugate IAP : Poly A binding protein : Poly aery lam ide gel electrophoresis : P21 activated kinase-2 : Poly (ADP-Ribose) Polymerase : Protein disulphide isomerase : Pancreatic endoplasrnic-resident elf2ot kinase : Protein kinase c delta : Double-stranded RNA-dependent eif2a kinase : Protein phosphatase 2 A : p53 up regulated modulator of apoptosis : Rho GTPase activated serine threonine kinase : repear : eif2a mutation of ser 51 eif2a to Ala : elf2a mutation of ser* 1 elf2a to Asp : Sodium dodecyl sulphate : Spodoptera frugiperda : Second mitochondria derived activator of caspase : Signal recognition particle : N\ N\ N\ N\ N'-tetra ethyl methyl ethyl diamine : Thapsigargin

3 ER : Endoplasmic reticulum ERK : Extra cellular regulated kinase ERP : Endoplasmic reticulum protein Et : Etoposide FADD : Fas associated death domain FCS : Fetal calf serum FKB13 : FK506 binding protein FLICE : Fas associated death domain-like interleukin converting enzyme FLIP : FLICE inhibitory protein GADD : Growth arrest DNA damage GCN2 kinase : General nonderepressible kinase GRP : Glucose response protein GSH : Reduced glutathione GST : Giutathione S-transferase HID : Head involution defective HRI kinase : Heme regulated inhibitor kinase HSP : Heat shock promoter Htr A2 : High temperature requirement protein A2 IAP : Inhibitor apoptosis of proteins IC AD : Inhibitor of caspase activated DNase ICE : Interleukin converting enzyme IFN : Inteferons IGL : Insulin growth factor IkB : Inhibitor of kappa B IL : Interleukin IREs : Internal ribosome entry sites JNK : c-jun-nh 2 terminal kinase KI : Kinase insertion MAPK : Mitogen activated protein kinase v

4 Met rng M01 NACa NAIP NBT NF-kB NP Omi OPIAP PABP PAGE PAK2 PARP PD1 PERK PKc5 PKR PP2A PUMA ROCK Rpr S51A S51D SDS SfV Smac SRP TEMED Tg : Methionine : milligram : Multiplicity of infection : Nascent associated complex a : Nucleotide binding apoptosis inhibitor protein : Nitro Blue Tetrazolium : Nuclear factor-kappa B : Nucleo capsid protein : Outer mitochondrial IAP binding protein : Orgyia pseuditsugate IAP : Poly A binding protein : Poly acrylamide gel electrophoresis : P21 activated kinase-2 : Poly (ADP-Ribose) Polymerase : Protein disulphide isomerase : Pancreatic endoplasmic-resident eif2a kinase : Protein kinase c delta : Double-stranded RNA-dependent eif2a kinase : Protein phosphatase 2 A : p53 up regulated modulator of apoptosis : Rho GTPase activated serine threonine kinase :repear : eif2a mutation of ser 51 eif2a to Ala : eif2a mutation of ser* 1 eif2a to Asp : Sodium dodecyl sulphate : Spodoptera frugiperda : Second mitochondria derived activator of caspase : Signal recognition particle : N\ N\ N\ N', N'-tetra ethyl methyl ethyl diamine : Thapsigargin vi

5 SRP : Signal recognition particle TEMED : N\ N\ N\ N\ N'-tetra ethyl methyl ethyl diamine Tg : Thapsigargin Tn : Tunicamycin TNFR-1 : Tumor necrosis factor receptor-1 TNFa : Tumour necrosis factor -alpha TRAF : TNF receptor adaptor factor TRAIL : TNF-reiated apoptosis inducing ligand TSP : Thrombospondin UPR : unfolded protein response UV light : Ultra violet light wt : wild type XIAP : X-linked Inhibitor of apoptosis Z-IETD-fmk : N-carbobenzoxy-isoleucine-glutamine-[O-methyl]- threonine-apartyl-[o-methyl]-fluoromethtylketone z-vad-fmk : N-carbobenzoxy-valyl-alanvl-aspartyl-[0-methyl]- fluoromethylketone ug : microgram vii

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