Mark K. Ono, M.D. CURRICULUM VITAE Ironwood Cancer & Research Centers a division of Ironwood Physicians, PC

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1 Mark K. Ono, M.D. CURRICULUM VITAE Ironwood Cancer & Research Centers a division of Ironwood Physicians, PC EDUCATION INTERNSHIP: Thomas Jefferson University Hospital Department of Radiation Oncology Philadelphia, PA University of Minnesota Department of Obstetrics and Gynecology Minneapolis, MN Doctor of Medicine University of Chicago Chicago, IL Bachelor of Science, Chemistry University of Urbana-Champaign Urbana-Champaign, IL ADDITIONAL TRAINING Prostate Interstitial Brachytherapy, Seattle Prostate Institute, Seattle, WA Head and Neck Oncology, University of San Francisco, San Francisco, CA Gynecological Oncology, National Cancer Institute of Mexico; 1996 Pediatric Radiation Oncology, St. Jude Children's Research Hospital, Memphis, TN Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA Brachytherapy, Pennsylvania Hospital Stereotactic Radiosurgery, Intraoperative Radiotherapy, Hyperthermia, Brachytherapy, and RTOG and Intergroup Clinical Trials, Thomas Jefferson University Hospital HONORS & AWARDS Chief Resident, Thomas Jefferson University Hospital, Jefferson Medical College, Department of Radiation Oncology American College of Radiation Oncology, Resident Award Program, Subspecialty Elective Training Grant 1

2 American Radium Society Visiting Oncologist Award Selected for Cancer Committee, Thomas Jefferson University Hospital College of Medicine Scholarship Awarded King's College / University of London Exchange Program Dr. Bertram A. Richardson Scholarship Honors in Behavioral Sciences Edward James Honor Scholar Dean's List Harold Jacobsen Educational Scholarship Paul W. Murdock Scholarship Teaching Assistantship in Chemistry ACTIVITIES PROFESSIONAL: Medical Director, Tuality/OHSU Cancer Center Initiated, OHSU Intensity Modulated Radiotherapy program Director, Tuality Community Tumor Board Board Member, Tuality Community Hospital Foundation Founded and organized Tuality Hospital Tumor Board Organized CT/Simulation process American Board of Radiology Task Force for New Item Development BrainLab Novalis Stereotactic Coordinator Assistant Principal Investigator, Phase II Trial of Motexafin Gadolinium in Patients with Glioblastoma Multiforme CT Simulation Coordinator Assistant Principal Investigator, Phase III Trial of Whole Brain Radiotherapy (WBRT) with or without Gadolinium Texaphyrin, a Radiation Sensitizer Stereotactic Radiosurgery Program Prostate Brachytherapy Program Member, Multidisciplinary Spinal Management Team Lecturer, Clinical Oncology Series for Kaiser Permanente Resident Physicians Assistant Chair, Kaiser Permanente Executive Cancer Committee, Metropolitan Los Angeles Cancer Committee, The Community Hospital Volunteer, The Community Hospital Prostate Cancer Screening Program American Cancer Society; Clinical Screening Program Appointed lecturer; Thomas Jefferson University, Jefferson Medical College, Clinical Oncology Series for Medical Students Department of Radiation Oncology, Radiation Oncology Resident Physicians' Library Department of Radiation Oncology, Resident Class Photograph Collection Department of Radiation Oncology, Excellence in Teaching Award and Chief Resident Physician Award 2

3 Organizer, Thomas Jefferson University Hospital, Department of Radiation Oncology, Clinical Oncology Lecture Series Organizer, Thomas Jefferson University Hospital, Department of Radiation Oncology, Didactic Pathology Conference Organizer, Thomas Jefferson University Hospital, Department of Radiation Oncology, Distinguished Visiting Professor Lectureship Organizer, Chief Resident Physicians of the Greater Philadelphia Region Group. Program to develop greater communication amongst residency training programs to improve educational pursuits for the regional resident physicians. Appointed, Committee Member, Simon Kramer Society; Annual Simon Kramer Society Lecture Committee Organized corporate sponsorship for Annual Simon Kramer Society Lecture Member, Simon Kramer Society CERTIFICATION Active member of the Chicago Medical Student Council Prepared article for Students to Students, M1 Guide Volunteer in Youth Health Outreach Program Participant in M1 Mock Anatomy exam Committee member to organize "Realities of Medicine Week" Program Active Board Member, Alpha Epsilon Delta Pre-medical Society Physiology tutor for Physiology 105 Volunteer medical care at local university events; Certified Emergency Medical Technician Illini Emergency Medical Services University of Illinois Jazz Band American Board of Radiology, Certified, Radiation Oncology National Board of Medical Examiners Diplomate PROFESSIONAL ORGANIZATIONS PUBLICATIONS American Society for Therapeutic Radiology and Oncology (ASTRO), Active Member L. Wilson, Jr., M. Ono, L. Fields, G. Flouret. Comparison of Binding of Oxytocin and an Oxytocin Antagonist (NU8702) to Oxytocin Receptors in the Pregnant Rat Uterus. Biology of Reproduction, 40: 71, NATIONAL PRESENTATIONS M. Miller, H. Greathouse, A. Olch, Y. Qian, C. Hewlett, D. Khan and M. Ono. Department of Radiation Oncology, Kaiser Permenente Southern California. Dose Versus Volume as Factors in Predicting Outcomes on 3

4 Radiosurgical Treatment of Arteriovenous Malformations. American Radium Society, London England, April 2000, Poster Presentation. M. Ono, N. Ahmad, M. Saiful Huq, J. Vernick, and F. Rosato. The Influence of Intraoperative Radiation Therapy (IORT) on Outcome of Surgically Resectable Adenocarcinomas of the Pancreas. Departments of Radiation Oncology and Surgery, Thomas Jefferson University Hospital, Jefferson Medical College, Philadelphia, PA ASTRO, 38th Annual Scientific Meeting, Los Angeles, CA, October, 1996, Poster Presentation. M. Ono, K. Radie-Keane, K. Engin, L. Komarnicky, L. Hoh, J. McFarlane, C.M. Mansfield, F.M. Waterman, and D.B. Leeper. Single Field Hyperthermia Combined with Radiotherapy in Recurrent or Advanced Carcinoma of the Breast. Department of Radiation Oncology, Thomas Jefferson University Hospital, Jefferson Medical College, Philadelphia, PA Radiological Society of North America, 95th Annual Meeting, Chicago, IL, November, 1995, Oral Presentation. L. Wilson, Jr., M. Ono, L. Fields, G. Flouret. Comparison of Binding of Oxytocin and an Oxytocin Antagonist (NU8702) to Oxytocin Receptors in the Pregnant Rat Uterus. Society for the Study of Reproduction, 22nd Annual Meeting, University of Columbia Campus, Columbia, MO, August, 1989, Poster Presentation. LOCAL PRESENTATIONS Tuality/OHSU Cancer Center Invited Lecturer, DeMar Batchelor Memorial Health Education Lecture Series, New Directions in Cancer Care, Lung Cancer: Searching for the Facts, April 2004 Oregon State Radiologic Technologists Fall Symposium; Gold Seed Localization for Prostate IMRT, October 2003 Invited Lecturer, Tillamook General Hospital, Prostate Cancer and an Introduction to Radiation Therapy, April 2003 Invited Lecturer, Tualatin Valley Insurance Associates, NAIW, Breast Cancer Screening and Treatment, March 2003 Invited Lecturer, Forest Grove Rotary Club, Introduction to the Tuality/OHSU Cancer Center, March 2003 Invited Lecturer, Hillsboro Rotary Club, Introduction to the Tuality/OHSU Cancer Center, February 2003 Invited Guest, Hablemos Sobre El Cancer, Radio Talk Show Program, KWIP 880AM, November 2002 Invited Lecturer, DeMar Batchelor Memorial Health Education Lecture Series, Radiation Treatment and Caregiver Strategies, Introduction to Radiation Therapy, October 2002 OHSU Resident Physician Lecture, Testicular Cancer, October 2002 Kaiser Hospital, Los Angeles Medical Center Stereotactic Radiosurgery Presentation, Department of Radiation Oncology Open House, May 2000 Lecturer, First Annual Oncology Symposium; Radiation Therapy Planning and Three- Dimensional CT Planning, Newport Beach, CA, 1999 The Community Hospital, The Community Oncology Center Lecturer, Indiana Society for Radiation Technologists Annual Meeting, AcQSIM, Three-Dimensional Simulation, Hammond, IN, 1998 Lecturer, Community Hospital Pavilion Open House; Prostate Seed Implantation for the Treatment of Prostate Cancer, 1998 Lecturer, Inservice Lecture for the Departments of Radiation Oncology and Radiology, AcQSIM Simulation; The Next Step, 1997 Tumor Board Presentation, 1997, 1998 Moderator, American Cancer Society, Breast Cancer Update 1997 Thomas Jefferson University, Jefferson Medical College 4

5 Clinical Oncology Conference; Resectable Adenocarcinomas of the Pancreas and Intraoperative Radiation Therapy; Kick the Cone or Keep It?, 1997 Lecturer, Sophomore Medical Students Clinical Lecture Series; Principles and Paradigms in Clinical Oncology, 1996, 1997 Quality Assurance Conference; The Effects of Radiation Therapy on the Kidney, 1996 Clinical Case Presentation; Treatment of Advanced Cervical Carcinomas, 1996 Clinical Oncology Conference; The Treatment of Recurrent or Advanced Carcinomas of the Breast with Concurrent Hyperthermia and Radiotherapy, 1995 Clinical Oncology Conference; The Radiobiology and Treatment of Melanomas, 1995 Quality Assurance Conference; The Morbidity and Mortality of Ionizing Radiation on Bone Marrow Function, 1994 Resident Review Session; Cervical Cancer: Treatment, 1994 Resident Review Session; Nasal Vestibule and Cavity, & Paranasal Sinuses, 1994 Resident Review Session; CNS/Low Grade Gliomas, 1994 Resident Review Session; Radiation Therapy in Palliative Cancer Management, 1993 RESEARCH The Influence of Intraoperative Radiation Therapy (IORT) on Outcome of Surgically Resectable Adenocarcinomas of the Pancreas. M. Ono, N. Ahmad, M. Saiful Huq, J. Vernick, and F. Rosato, Department of Radiation Oncology and Surgery, Thomas Jefferson University Hospital, Jefferson Medical College, Philadelphia, PA Single Field Hyperthermia Combined With Radiotherapy In Recurrent or Advanced Carcinoma of the Breast. M. Ono, K. Radie-Keane, K. Engin, L. Komarnicky, L. Hoh, J. McFarlane, C.M. Mansfield, F.M. Waterman, and D.B. Leeper. Department of Radiation Oncology, Thomas Jefferson University Hospital, Jefferson Medical College, Philadelphia, PA Comparison of Binding of Oxytocin and an Oxytocin Antagonist (NU8702) to Oxytocin Receptors in the Pregnant Rat Uterus. L. Wilson, Jr., M. Ono, L. Fields, G. Flouret. Department of Obstetrics and Gynecology, University of Illinois at the Medical Center and Department of Physiology and Northwestern University Medical School, Chicago, IL, Esophageal Manometry Measurements in Patients with Gastroesophageal Reflux. C. Bombeck, J. DeSalvo, and M. Ono. Department of Gastroenterological Surgery, University of Illinois at the Medical Center, Chicago, IL,