Table 2.3 Cohort studies of painters and bladder cancer

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1 Cohort decription Expoure aement Organ ite Expoure categorie cae/ death Comment OPCS (1958) Regitered death of 221,941 men aged yr in the broad occupational category of painter and decorator Occupation at time of death or lat occupation from death certificate; Occupation coded according to the Cenu 1951, Claification of Occupation (ICD6 181.) Other painter & decorator Aerographer, paint prayer 58 3 [1.09 ( )] [1.50 ( )] Age, ex Reference, population of England and Wale Enterline & McKiever (1963); Guralnick (1963) 1950 Men aged who died in the in 1950 Uual occupation and indutry recorded from death certificate, coded uing International Occupational Claification and other urinary organ (ICD 181) Painter and platerer White Non-white Painter (contruction), paperhanger, glazier White Non-white [ ] 1.46 [ ] 1.43 [ ] 1.45 [ ] Age, race Reference, 1950 US cenu population OPCS (1971) Regitered death of men aged in England and Wale Lat occupation recorded on the death certificate? (181.) Painter & decorator [ ] Age, ex Reference, population of England and Wale 1

2 Cohort decription Expoure aement Organ ite Expoure categorie cae/ death Comment OPCS (1978), no Regitered death of 273,129 men aged Lat occupation recorded on the death certificate, a coded by the 1970 Claification of Occupation (188) Painter & decorator [ ] Age, ex Reference, population of England and Wale; The occupation unit of painter and decorator wa compried of aerographer, paint prayer, painter, decorator n.e.c., coach painter Logan (1982) Mortality of men in , age Occupation recorded at the time of cancer regitration/death and coded uing variou method Painter & decorator yr (1951) yr (1961) yr (1971) 1.09 () 1.18 () 1.52 () Age, ex, year Reference, all men in the 3 or 5 year period under review; Baed upon decennial occupational mortality analye of the Regitrar General of England and Wale ( ); Excluded from meta-analyi becaue of overlap with OPCS 1958, 1971, 1978 and lack of data to calculate confidence interval 1931 data Whorton et al (1983) painting union member (2197 men, 3 women) linked to the Calinia Tumor Regitry union memberhip file (ICDO ) Painter 3 SIR 1.31 [ ] Age, ex, year Reference, mid-year SMSA Calinia population OPCS (1986), no , Men aged in Great Britain who died during and Mortality of men aged in England & Wale in 1981 Lat full-time occupation recorded on the death certificate, coded by the OPCS 1980 occupational claification (ICD9 188) Painter, decorator, french poliher Painter & decorator [ ] 1.52 () Age, ex Reference, population of Great Britain, England & Wale, or Scotland a appropriate 2

3 Cohort decription Expoure aement Organ ite Expoure categorie cae/ death Comment Matanoki et al (1986) Mortality of white male painter and allied trademen currently or merly member of a painter union > 1 year during ; 33,098 men from mixed local were primarily or excluively painter Painter union record from local chapter (ICD 188) Mixed local member, coniting primarily or excluively of painter ( ) Age Reference, US white male; The union repreent mot unionized painter in the US; Excluded from meta-analyi becaue later updated by Steenland & Palu Malker et al (1987) Sweden The 1960 Swedih cenu wa linked to the Swedih Cancer Regitry to follow-up bladder cancer incidence from Occupation and indutrie were obtained from the 1960 cenu and coded uing ILO tandard. Painter a one pecific occupation Artitic painter SIR (p-value) 1.0 (not given) 1.7 [ ] Age, ex, region The cenu code i not given artitic painter and thu may correpond to the Swedih pictorial aritit tudied in Brown et al (2002). Excluded from meta-analyi becaue artit have different expoure than painter Olen & Jenen (1987) Denmark ,166 male incident cancer cae from the Danih Cancer Regitry were linked with employment record Longet employment held from penion fund regitrie, coded uing ISIC including papilloma (ICD7 181) Painter in the contruction indutry 24 SPIR 1.12 ( ) Age, time Reference, Danih population; No inmation on moking habit available. An earlier tudy howed that 60-80% of Danih men, aged year, moked; SPIR approximate the SIR when the cancer under invetigation contitute a minor part of all the malignancie included in the tudy and when expoure ha no effect on cancer rik in general. 3

4 Cohort decription Expoure aement Organ ite Expoure categorie cae/ death Comment Excluded from meta-analyi becaue of large overlap with Pukkala et al (2009). Dolin & Cook- Mozaffari (1992) Male Britih painter, aged 25-64, who died from bladder cancer during Inmation on occupation and indutry of uual employment wa extracted from death certificate and coded according to Englih tandard All painter Coach painter Painter, decorator Spray painter ( ) 7.03 ( ) 1.20 ( ) 0.92 ( ) Age, urbanizatio n Degree of urbanization wa ued a a proxy moking data that were unavailable. Excluded from the meta-analyi becaue of overlap with OPCS 1978, 1986 Skov et al (1993) Denmark , Finland , Norway , Sweden economically active, male painter and lacquerer included in the national cenu of 4 Scandinavian countrie were followed-up cancer incidence by linking individual record with national cancer regitrie Painter were identified by combining cenu code occupation and indutry Painter 380 [1.05 ( )] Birth cohort, ex, ite Reference, economically active cenu population or total population in ame region (Sweden only); Excluded from meta-analyi becaue of overlap with Pukkala et al (2009). 4

5 Cohort decription Expoure aement Organ ite Expoure categorie cae/ death Comment Hrubec et al (1995) painter were followed during within a cohort aembled from a roter of approximately white male WWI veteran who erved in the US Armed Force ome time during and who held active government life inurance policie Mailed quetionnaire that inquired about tobacco ue, uual indutry of employment and occupation, coded uing 1950 Cenu Occupation and Indutry code Painter, contruction and maintenance [ ] Smoking, age, time Reference, US white male Anderen et al Denmark , Finland , Norway , Sweden male and 2121 female painter and wallpaper hanger, aged year at 1970 cenue, were followed-up cancer incidence during by linkage to national cancer regitrie Occupation wa obtained from cenu data and coded according to national adaptation of the Nordic Occupational Claification or according to a pecial Danih nomenclature. Painter & wall paper hanger Men Women ( ) 1.46 ( ) Age, ex, Reference, national population; The Swedih component partly overlap Brown et al (2002) who alo included painter from the 1960 Swedih cenu. Excluded from meta-analyi becaue of overlap with Pukkala et al (2009). 5

6 Cohort decription Expoure aement Organ ite Expoure categorie cae/ death Comment Steenland & Palu painter and non-painter with > 1 yr union memberhip were identified from union record and followed from by linkage to national and local regiter; Retricted to white men (98% of the cohort). Job title were inferred from union memberhip record which identified the pecialty affiliation and trade of the local union all member Painter ( ) Age, time. Update of Matanoki et al (1986);Reference, general US population; No inmation on trade of individual member; SRR compared painter to nonpainter; Brown et al (2002) Sweden People in the painting trade or painting indutry ( male painter and 6662 male and 2136 female pictorial artit) obtained from 1960 and 1970 Swedih cenu data were linked to the Cancer Environment Regiter to follow-up cancer incidence from Job title and indutry were obtained from cenu data and coded uing Swedih occupational code. Male painter (claified either in 1960 or 1970) ( ) Age, ex, year Reference, national population; Lung cancer rik wa not increaed among artit; Excluded from meta-analyi becaue of overlap with Pukkala et al (2009) 6

7 Cohort decription Expoure aement Organ ite Expoure categorie cae/ death Comment Pukkala et al (2009) Denmark , Finland , Iceland , Norway , Sweden million people aged year in the 1960, 1970, 1980/1981 and/or 1990 cenue and the 2.8 million incident cancer cae diagnoed in thee people in a follow-up until about 2005 were linked to Nordic national regitrie Occupation from elfadminitered cenu quetionnaire, coded uing ISCO code adapted to Nordic countrie bladder, ureter, and urethra Painter Men Women [1.08 ( )] 1.08 ( ) 1.52 ( ) Country, ex, age, period Reference = national population; Etimated 69.1% of Norwegian male painter moked; Nordic Occupational Cancer (NOCCA) project; Update of Anderen et al Abbreviation: RR, relative rik; SIR, tandardized incidence ratio; SMR, tandardized mortality ratio; CI, confidence interval; ASCR, Aociation of Swi Cancer Regitrie; SIC, Standard Indutrial Claification; ISCO, International Standard Claification of Occupation; ISIC, International Standard Indutrial Claification;, not given 7

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