Catalog Romer Labs Products and Services

Transcription

1 Catalog 2014 Romer Labs Products and Services

2 New Products Content Food Allergens: AgraQuant F.A.S.T. Almond page 33 AgraQuant F.A.S.T. Casein page 33 AgraQuant F.A.S.T. Egg page 33 AgraQuant F.A.S.T. Hazelnut page 33 AgraQuant F.A.S.T. Macadamia Nut page 33 AgraQuant F.A.S.T. Peanut page 33 AgraQuant F.A.S.T. Cashew page 33 AgraQuant F.A.S.T. Mustard page 33 AgraStrip Wine Extraction Buffer (Casein) page 34 AgraStrip Wine Extraction Buffer (Egg) page 34 AgraStrip Milk page 34 AgraStrip Beta-Lactoglobulin page 34 AgraStrip Crustacea page 34 : AgraQuant T-2/HT-2 page 19 StarLine R columns page 22 Biopure MRM Aflatoxin in Pistachio page 28 Biopure CSM Aflatoxin in Maize page 29 GMO: AgraStrip GMO Low-LOD semi-quantitative TraitChek page 43 Romer Labs Worldwide... 4 Romer Labs Products and Solutions Aflatoxins... 9 Ochratoxins...12 Trichothecenes...13 Fumonisins...15 Zearalenone...17 T-2/HT-2 Toxin...19 Ergot Alkaloids...21 Cleanup Columns...22 Rapid Tests...23 Reference Materials...24 Enzymatic Food Analysis...30 Food Allergens...32 Food Pathogens...36 Ruminant Meat & Bone Meal...38 GMO...40 Residues + Adulterants...44 Check Sample Survey...47 Analytical Service...48 Equipment...52 Enzymatic: EnzymeFast Lactose/D-Glucose page 31 Food Pathogens: RapidChek Listeria F.A.S.T. Environmental System page 37

3 Worldwide Romer Labs Cheshire (UK) Herzogenburg Austria AgraQuant ELISA Test Romer Labs was founded in Washington, MO, in Now, three decades later, Romer Labs has seven business units Union, MO (USA) San Antonio Newark, DE (USA) Beijing (China) Malaysia Singapore AgraStrip Lateral Flow Devices (USA, Austria, Singapore, Brazil, China, United Kingdom and Malaysia) on three continents and is represented in more than 60 countries worldwide through dedicated Campinas (Brazil) RapidChek Pathogen Detection distributors. Over the years, it has become the number- Romer Labs Subsidiary Romer Labs Distributor FluoroQuant Fluorometric Test one, niche provider of diagnostic solutions for the agricultural, food and feed industry. Its broad range of innovative tests and services Romer Labs Diagnostic GmbH Technopark 1, A-3430 Tulln, Austria Tel: Fax: Romer Labs Inc Stylemaster Drive Union, MO , USA Tel: Fax: Romer Labs do Brasil Imp. e Exp. Ltda. Estr. Municipal Campinas/ B. Campo Grande, s/n, km 8.5 Caixa Postal N 1082, CEP Campinas/SP, Brazil Tel: Fax: vendas@romerlabs.com.br Romer Labs UK Ltd. Block 5, The Heath Business & Technical Park Runcorn, Cheshire WA7 4Q Tel: enquiry@romerlabs.com Romer Labs Singapore Pte. Ltd Jalan Bukit Merah #08-08, e-centre@redhill Singapore Tel: Fax: salesasia@romerlabs.com Romer Labs (Beijing) Co. Ltd Jia Tai International Mansion 41 East 4 th Ring Middle Road, Chaoyang District Beijing , China Tel: Fax: officechina@romerlabs.com Romer Labs Malaysia Sdn Bhd Suite 218, 2 nd Floor Eureka Complex Universiti Sains Malaysia Penang Malaysia Tel: Fax: officemalaysia@romerlabs.com Romer Labs Technology, Inc. 130, Sandy Drive Newark, DE 19713, U.S.A. Tel: Fax: rapidchek@romerlabs.com Page 4 MycoSep and MultiSep Cleanup Columns StarLine Immunoaffinity Columns Biopure Standards, Calibrants and Reference Materials Analytical Service EnzymeFast Laboratory Equipment Page 5 play a pivotal role in integrated food safety solutions. Romer Labs is at the forefront of diagnostic technology and is constantly expanding its product and service portfolio to meet the continuously evolving demands of its customers, supplying products and services in the fields of mycotoxins, food pathogens, food allergens, GMO and veterinary drug residues. The key objective at Romer Labs is to provide scientifically sound, high-quality products and services, in line with its mission -

4 AgraQuant ELISA Tests The Romer Labs AgraQuant product family is a range of enzyme-linked immunosorbent assay (ELISA) test kits that encompasses mycotoxin, allergen, GMO and drug residue tests. ELISA tests are quantitative tests. Reactions are read by a specific ELISA reader, such as the StatFax and the Chromate ELISA reader, for quantification purposes. A set of five to six standards used for calibration is supplied with all test kits to determine a result. Creating a new calibration curve with every assay setup assures high accuracy and reproducibility. The results obtained are comparable to HPLC results. AgraQuant kits are direct competitive ELISAs for mycotoxin and drug residue tests and sandwich ELISAs for allergen and GMO tests. All AgraQuant ELISAs use specific antibody coated microwells and an enzyme-labeled analyte conjugate. The quality of the antibody is crucial for test-result quality. Romer Labs has a broad range of monoclonal antibodies, which are highly specific to the respective analyte and guarantee robust and accurate results. AgraStrip Lateral Flow Devices The Romer Labs AgraStrip product family utilizes lateral flow technology, also known as immunochromatography tests. Most lateral flow devices (LFD) come in a format that is often called a dip stick or strip test. While the use of this technology is very widespread in the clinical field, the food safety market has only seen suitable applications in the last few years. AgraStrip LFDs use specific antibodies labeled with colloidal gold for visual color development at a test and control zone. Developed LFDs can be read visually, making instrumentation redundant. They normally produce only a yes/no answer, indicating the presence or absence of an analyte at a defined concentration. However, if instruments such as the Romer Labs AgraVision are used, LFDs can be read, providing a quantitative result. RapidChek Pathogen Detection As a food processor, choosing the best pathogen detection method can be a very difficult decision. The method should have a meaningful impact on the total cost of a food safety program but most importantly, provide maximum assurance of reliability in the test results. As a food safety professional, you know that it s not just a test result. It is information that will help to protect your customers and essentially your business. Romer Labs RapidChek and RapidChek SELECT product lines were developed to deliver the simplicity, speed and high accuracy necessary every day. Our technology sets us apart from other rapid test methods. The RapidChek product family utilizes highly selective enrichment media coupled to advanced lateral flow immunochemical detection of food pathogens such as Salmonella spp., Listeria spp., and Escherichia coli O157 in various foodstuffs and environmental applications. Patented phage technology used in the SELECT system suppresses the growth of competitive microflora which creates optimal growth conditions for Salmonella spp. Highly specific monoclonal and polyclonal antibodies are exclusive to the RapidChek system which works without the need for expensive equipment or extensive training. RapidChek. Simply Accurate. FluoroQuant Fluorometric Test The FluoroQuant Test Kits are the fastest, quantitative fluorometric tests based on a solidphase or immunoaffinity column cleanup. They are USDA/GIPSA approved and AOAC Performance Tested. These tests provide a wide quantitation range without dilution steps. The FluoroQuant tests are simple enough for field use in grain, feed and food handling facilities, but they are also appropriate for analytical laboratories. Each kit comes complete with all test and accessory materials such as columns, filter paper, pipette tips, cuvettes and reagents. The FluoroQuant Test kits require an FQ-Reader, which reads the fluorescence signal of the test and translates it into a quantitative analytical result. The FQ-Reader comes with a touch screen and can be connected to a PC and a printer. MycoSep and MultiSep Cleanup Columns In order to shorten the sample cleanup process, Romer Labs has developed a product portfolio of one-step-cleanup columns for different groups of mycotoxins. MycoSep and MultiSep columns contain packing materials made of absorbent mixes designed for all relevant food and feed commodities. MycoSep columns allow a one-step cleanup within 30 seconds: the MycoSep cleanup column is pushed into a test tube containing the sample extract, forcing the extract to filter upwards through the packing material of the column. The interferences adhere to the chemical packing in the column and the purified extract, containing the analytes of interest, passes through the column. Similarly to the MycoSep column format, the MultiSep column format allows a onestep cleanup of sample extracts, containing the analyte of interest, within 30 seconds: the sample extract is applied on top of the MultiSep cleanup column, allowing the extract to go through the packing material of the column by gravity, or Page 6 alternatively, by forcing the extract through the column material via the application of vacuum or positive pressure. Page 7 MycoSpin Romer Labs has developed a spin column that can be used for the majority of regulated mycotoxins to shorten the time-consuming cleanup process for the simultaneous analysis of multiple mycotoxins. The MycoSpin 400 Multitoxin spin column contains a combination of adsorbents that was designed for the purification of complex commodity extracts for subsequent LC-MS/MS multi-mycotoxin analysis. This cleanup column has been studied intensively and application briefs are available. StarLine Immunoaffinity Columns Romer Labs wide range of immunoaffinity columns (IAC) for regulated mycotoxins is based on a specific antibody-analyte binding technology. StarLine immunoaffinity columns are designed for simple and reliable cleanups before the detection of mycotoxins in a broad range of foodstuffs and animal feed. Immunoaffinity columns contain a gel bed with toxin-specific antibodies coupled to the gel particles. These antibodies will capture mycotoxins in a sample and release them again after a washing stage. StarLine immunoaffinity columns have been validated in an extensive testing program and can be used for the purification and concentration of mycotoxins prior to the analysis by various techniques, such as HPLC, LC-MS, GC-MS, ELISA or direct fluorometry. All Romer Labs IAC employ highly specific monoclonal antibodies. Biopure Standards, Calibrants and Reference Materials Biopure is a Romer Labs brand which stands for high quality reference materials. All Biopure products are characterized by the appropriate independent methods, such as HPLC, NMR and MS. The selection of the right method is crucial to ensuring the identity and purity of the reference material. Biopure reference materials are accompanied by a certificate. The certificate states the uncertainty of the target analyte and documents the traceability of the certified value, expressed in SI conform units. The Certificate of Analysis is supplied in accordance to ISO Guide 31. Biopure has the broadest range of mycotoxin reference materials currently available globally. In addition to mycotoxins, Biopure supplies standards for veterinary drug residues, and other contaminants such as melamine. The stars of this product line are the fully labeled C13 internal standards, which are unique and rely on a patented technology, proprietary to Romer Labs. C13 standards play a crucial role in LC-MS/ MS analysis and are widely used in multi-analyte methods. Analytical Service Romer Labs currently operates service laboratories in four countries: Austria, Singapore, the United Kingdom and the United States. All these laboratories are accredited according to ISO and offer a broad range of services for allergens, mycotoxins, GMOs and veterinary drug residues. The Romer Labs service laboratories employ cutting edged technology and are equipped with the latest generation of equipment. Laboratory Equipment Romer Labs aims to provide full set-up packages for its diagnostic solutions. Using the right equipment is essential to performing a method correctly. Romer Labs provides a series of readers for its rapid test kits, such as the AgraVision (for Lateral Flow Tests) or the Chromate (for ELISA tests). For instrumental analysis, Romer Labs has different instruments available that help improve method performance, such as the RDU (Romer Derivatization Unit) used for Aflatoxins analysis in HPLC-FLD. Romer laboratory mills have set the standard in sample preparation in mycotoxin analysis for over 25 years and are referenced in numerous official methods (AOAC, USDA, FAO, etc.) and scientific publications. Many multinational food and feed companies use Romer mills in their daily routine and the products are known for their reliability and robustness. EnzymeFast EnzymeFast tests are enzymatic tests in a micotiter plate format. Enzymatic food analysis is a basic method used for the measurement of compounds such as sugars, acids, alcohols and other metabolites in foods and beverages. In general, enzymes are proteins that catalyze the conversion of one molecule into another. Certain enzymatic reactions lead to color formation or consumption that often takes place in a wavelength range invisible to the human eye. This change in intensity can be measured. The high specificity of enzyme reactions allows for the analysis of food components in complex matrices.

5 AFLATOINS FAO estimates global losses of foodstuffs due to mycotoxins, are in the range of 1000 million tonnes per year. Many species of fungi can produce a vast number of different mycotoxins. The presence of these toxins in food and feed can be of major concern in food and feed safety. Generally speaking, if elevated levels of mycotoxins are indicated, this can result in toxic, mutagenic and teratogenic effects and lead to symptoms such as skin irritation, immune suppression and neurotoxicity, as well as to potential birth defects and death. The effects can be chronic or acute, depending on the concentration involved. are typically highly resistant to temperature and processing. Therefore, they cannot be destroyed during conventional food or feed production and can also be found in finished, processed products. Analytical procedures to find and identify mycotoxins are essential in ensuring proper risk management. Technologies and products are available for official field or on-site reference testing, depending on the intended use. Romer Labs offers a wide range of mycotoxin solutions, such as clean-up columns and reference materials for reference testing, as well as a complete portfolio of test kits for rapid testing. AgraQuant ELISA Tests Item No. Quantitation Range Limit of Detection No. of Tests AgraQuant Total Aflatoxin COKAQ ppb 1 ppb 96 COKAQ ppb 1 ppb 48 COKAQ ppb 3 ppb 96 COKAQ ppb 3 ppb 48 AgraQuant Aflatoxin B1 COKAQ ppb 2 ppb 96 COKAQ ppb 2 ppb 48 AgraQuant Aflatoxin M1 COKAQ ppt 18 ppt 96 COKAQ ppt 89 ppt 96 AgraStrip Lateral Flow Devices Item No. Quantitation Range Limit of Detection No. of Tests AgraStrip Afla COKAS ppb 24 COKAS1100U 2 incl. Whirl-Pak bags 4 ppb 24 COKAS ppb 24 COKAS1200U 1 incl. Whirl-Pak bags 10 ppb 24 COKAS ppb 24 COKAS1000U 1 20 ppb 24 COKAS1600A for AgraVision ppb 3.6 ppb 24 FluoroQuant Fluorometry Item No. Version Limit of Detection No. of Tests FluoroQuant Afla COKFA ppb 25 FluoroQuant Afla Plus COKFA Acetonitrile from 0.5 ppb 25 COKFA3070D 3 Methanol from 0.5 ppb 25 FluoroQuant Afla IAC COKFA US Domestic Version 3 ppb 25 COKFA4020 International Version 3 ppb 25 Page 8 Page 9 1 USDA/GIPSA approved 2 Japanese Department of Agriculture approved 3 AOAC RI approved

6 AFLATOINS AFLATOINS StarLine Immunoaffinity Columns AflaStar Item No. Product Format No. of Columns COIAC1001 AflaStar FIT 1 ml 25 COIAC1501 AflaStar FIT 1 ml 500 COIAC1004 AflaStar R 3 ml 25 COIAC1504 AflaStar R 3 ml 500 COIAC1005 AflaStar M1 R 3 ml 25 MycoSep & MultiSep Cleanup Columns MycoSep MultiSep Item No. Product Specificity No. of Columns COCMY2112 MycoSep 112 AflaZon Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMY2224 MycoSep 224 AflaZon 4 Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMY2226 MycoSep 226 AflaZon+ Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMY2228 MycoSep 228 AflaPat 5 Aflatoxins B1, B2, G1 & G2, Patulin 25 COCMU2224 MultiSep 224 AflaZon Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMU2226 MultiSep 226 AflaZon+ Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMU2228 MultiSep 228 AflaPat 5 Aflatoxins B1, B2, G1 & G2, Patulin 25 Calibrant Solutions Aflatoxin B1 (AFB1), 2 µg/ml in acetonitrile 5 ml S02017 Aflatoxin B1 (AFB1), 2 µg/ml in acetonitrile 1 ml Aflatoxin B2 (AFB2), 0.5 µg/ml in acetonitrile 5 ml S02018 Aflatoxin B2 (AFB2), 0.5 µg/ml in acetonitrile 1 ml Aflatoxin G1 (AFG1), 2 µg/ml in acetonitrile 5 ml S02019 Aflatoxin G1 (AFG1), 2 µg/ml in acetonitrile 1 ml Aflatoxin G2 (AFG2), 0.5 µg/ml in acetonitrile 5 ml S02020 Aflatoxin G2 (AFG2), 0.5 µg/ml in acetonitrile 1 ml Aflatoxin M1 (AFM1), 0.5 µg/ml in acetonitrile 5 ml S02030 Aflatoxin M1 (AFM1), 0.5 µg/ml in acetonitrile 1 ml Calibrant Mixtures MI 1 (Aflatoxins) 5 ml S02021 MI 1 (Aflatoxins) 1 ml MI 5 (Aflatoxins) 6 ml S02022 MI 5 (Aflatoxins) 1 ml LMY-092-5mL MI 9 (Aflatoxins) 5 ml Stable Isotope Labeled Calibrant Mixtures* ILMO ml MI 11 ( 13 C Aflatoxins) 1.2 ml Solid Standards Aflatoxin B1 (99.5 ± 0.5 purity) 5 mg Aflatoxin B2 (99.7 ± 0.3 purity) 5 mg Aflatoxin G1 (98.0 ± 2.0 purity) 5 mg Aflatoxin G2 (97.1 ± 2.9 purity) 5 mg Stable Isotope Labeled Standards ILM010 U-[ 13 C 17 ]-Aflatoxin B1 (0.5 µg/ml) in acetonitrile 1.2 ml ILM ML U-[ 13 C 17 ]-Aflatoxin B2 (0.5 µg/ml) in acetonitrile 1.2 ml ILM ML U-[ 13 C 17 ]-Aflatoxin G1 (0.5 µg/ml) in acetonitrile 1.2 ml ILM ML U-[ 13 C 17 ]-Aflatoxin G2 (0.5 µg/ml) in acetonitrile 1.2 ml ILM ML U-[ 13 C 17 ]-Aflatoxin M1 (0.5 µg/ml) in acetonitrile 1.2 ml Matrix Reference Materials Aflatoxin in Pistachios 55 g Afla B1: 34.0 µg/kg ± 0.9 µg/kg Afla B2: 2.4 µg/kg ± 0.1 µg/kg Afla G1: < 0.1 µg/kg, Afla G2: < 0.1 µg/kg, Afla total: 36.0 µg/kg ± 1.0 µg/kg Check Sample Materials Aflatoxins in Maize 100 g Afla B1: 4.06 μg/kg ± 1.05 μg/kg; Afla B2: 0.46 μg/kg ± 0.15 μg/kg; Afla G1:< 0.1 μg/kg; Afla G2: < 0.1 μg/kg; Afla total: 4.52 μg/kg ± 1.20 μg/kg Aflatoxins in Maize 100 g Afla B1: 9.62 μg/kg ± 2.70 μg/kg; Afla B2: 0.74 μg/kg ± 0.26 μg/kg; Afla G1: 0.68 μg/kg ± 0.28 μg/kg; Afla G2: < 0.1 μg/kg ± 0.28 μg/kg; Afla total: μg/kg ± 3.24 μg/kg Page 10 Page 11 4 AOAC Offical Method 5 Japanese Official Method * composition see page 27 These products represent naturally contaminated materials and have a limited supply. Subsequent products might have different characteristics.

7 OCHRATOINS TRICHOTHECENES AgraQuant ELISA Tests Item No. Quantitation Range Limit of Detection No. of Tests AgraQuant Ochratoxin COKAQ ppb 1.9 ppb 96 COKAQ ppb 1.9 ppb 48 StarLine Immunoaffinity Columns Item No. Product Format No. of Columns OchraStar COIAC2001 OchraStar FIT 1 ml 25 COIAC2004 OchraStar R 3 ml 25 COIAC2504 OchraStar R 3 ml 500 MycoSep & MultiSep Cleanup Columns Item No. Product Specificity No. of Columns MycoSep COCMY2229 MycoSep 229 Ochra Ochratoxin A 25 MultiSep COCMU2229 MultiSep 229 Ochra Ochratoxin A 25 Calibrant Solutions Ochratoxin A (OTA) in acetonitrile 5 ml S02023 Ochratoxin A (OTA) in acetonitrile 1 ml S02052 Ochratoxin B (OTB) in acetonitrile 1 ml S02053 Ochratoxin-alpha (OTα) in acetonitrile 1 ml Solid Standards AgraQuant ELISA Tests Item No Quantitation Range Limit of Detection No. of Tests AgraQuant Deoxynivalenol COKAQ ppb 1,2 200 ppb 96 COKAQ ppb 1,2 200 ppb 48 AgraStrip Lateral Flow Devices Item No. Quantitation Range Limit of Detection No. of Tests AgraStrip DON Quantitative COKAS4000A ppb 140 ppb 24 for AgraVision StarLine Immunoaffinity Columns Item No. Product Format No. of Columns DONStar COIAC5004 DONStar R 3 ml 25 COIAC5504 DONStar R 3 ml 500 MycoSep MycoSep & MultiSep Cleanup Columns Item No. Product Specificity No. of Columns COCMY2113 MycoSep 113 Trich Trichothecenes, Type A & B 25 COCMY2225 MycoSep 225 Trich 3, 5 Trichothecenes, Type A & B 25 COCMY2227 MycoSep 227 Trich+ 4 Trichothecenes, Type A & B 25 MultiSep COCMU2216 MultiSep 216 Trichothecenes, Type A & B 25 COCMU2225 MultiSep 225 Trich Trichothecenes, Type A & B 25 COCMU2227 MultiSep 227 Trich+ 4 Trichothecenes, Type A & B Ochratoxin A (99.5 ± 0.5 purity) 5 mg Ochratoxin A (99.5 ± 0.5 purity) 10 mg Stable Isotope Labeled Standards ILM007 U-[ 13 C 20 ]-Ochratoxin A (10 µg/ml) in acetonitrile 1.2 ml Check Sample Materials Ochratoxin A in Wheat 100 g (8.6 ± 3.6 µg/kg) These products represent naturally contaminated materials and have a limited supply. Subsequent products might have different characteristics. Page 12 Page 13 1 Japanese Department of Agriculture approved 2 AOAC RI approved 3 AOAC offical method 4 Japanese official method 5 Chinese Quarantine Inspection method

8 TRICHOTHECENES FUMONISINS Calibrant Solutions Acetyl-Deoxynivalenol (15-AcDON) in acetonitrile 5 ml S Acetyl-Deoxynivalenol (15-AcDON) in acetonitrile 1 ml Acetyl-Deoxynivalenol (3-AcDON) in acetonitrile 5 ml S Acetyl-Deoxynivalenol (3-AcDON) in acetonitrile 1 ml Deepoxy-deoxynivalenol in acetonitrile 5 ml S02033 Deepoxy-deoxynivalenol in acetonitrile 1 ml Deoxynivalenol (DON) in acetonitrile 5 ml S02009 Deoxynivalenol (DON) in acetonitrile 1 ml S02046 Deoxynivalenol-3-glucoside in acetonitrile 1 ml Calibrant Mixtures* MI 4-3-AcDON,DON,NIV,Fus,HT-2,T-2,DAS,ZON 5 ml S02002 MI 4-3-AcDON,DON,NIV,Fus,HT-2,T-2,DAS,ZON 1 ml LMY-093-5mL MI 8 - DON, HT-2, T-2, ZON 5 ml Stable Isotope Labeled Calibrant Mixtures* ILM mL MI C 15 DON, 13 C 22 HT-2, 13 C 24 T-2, 13 C 18 ZON 1.2 ml on request Solid Standards Acetyldeoxynivalenol (98.8 ± 1.2 purity) 5 mg Acetyldeoxynivalenol (98.8 ± 1.2 purity) 10 mg Acetyldeoxynivalenol (99.4 ± 0.6 purity) 5 mg Acetyldeoxynivalenol (99.4 ± 0.6 purity) 10 mg Deoxynivalenol (99.4 ± 0.6 purity) 5 mg Deoxynivalenol (99.4 ± 0.6 purity) 10 mg Stable Isotope Labeled Standards ILM006 U-[ 13 C 17 ]-3-Acetyl-Deoxynivalenol (25 µg/ml) in acetonitrile 1.2 ml U-[ 13 C 17 ]-Deoxynivalenol (25 µg/ml) in acetonitrile 1.2 ml Matrix Reference Materials Deoxynivalenol in Wheat (877 ± 23 µg/kg) 55 g Deoxynivalenol in Maize (1840 ± 30 µg/kg) 55 g Check Sample Materials Zearalenone and Deoxynivalenol in Maize ZON (79 ± 26 µg/kg), DON: 901 ± 110 µg/kg) Deoxynivalenol in wheat DON: 143 ± 256; Sum of 3AcDON and 15 AcDON < g These products represent naturally contaminated materials and have a limited supply. Subsequent products might have different characteristics. AgraQuant ELISA Tests Item No. Quantitation Range Limit of Detection No. of Tests AgraQuant Fumonisin COKAQ ppb 200 ppb 96 COKAQ ppb 200 ppb 48 AgraStrip Lateral Flow Devices Item No. Quantitation Range Limit of Detection No. of Tests AgraStrip Fumonisin Quantitative COKAS3000A for AgraVision ppb 300 ppb 24 StarLine Immunoaffinity Columns Item No. Product Format No. of Columns FumoniStar MycoSep MultiSep COIAC3000 FumoniStar 3 ml 25 MycoSep & MultiSep Cleanup Columns Item No. Product Specificity No. of Columns COCMY2231 MycoSep 231 FUM Fumonisin B1, B2 & B3 25 COCMU2211 MultiSep 211 FUM Fumonisin B1, B2 & B3 25 Calibrant Solutions Fumonisin B1 (50 µg/ml) in acetonitrile/water 5 ml S02003 Fumonisin B1 (50 µg/ml) in acetonitrile/water 1 ml Fumonisin B2 (50 µg/ml) in acetonitrile/water 5 ml S02004 Fumonisin B2 (50 µg/ml) in acetonitrile/water 1 ml S02007 Fumonisin B3 (50 µg/ml) in acetonitrile/water 1 ml LMY-087-1ML Hydrolyzed Fumonisin B1 (25 µg/ml) in acetonitrile/water 1 ml on request Calibrant Mixtures* MI 3 - Fumonisin B1 & B2 (50 µg/ml each) in AcN/water 5 ml S02006 MI 3 - Fumonisin B1 & B2 (50 µg/ml each) in AcN/water 1 ml *composition see page 27 Page 14 Page 15 Stable Isotope Labeled Calibrant Mixtures* ILM ML MI C 34 Fumonisin B1 & B2 (50 µg/ml each) in AcN/water 1.2 ml on request *composition see page 27

9 FUMONISINS ZEARALENONE Solid Standards Fumonisin B1 (97.6 ± 2.4 purity) 5 mg Fumonisin B1 (97.6 ± 2.4 purity) 10 mg Stable Isotope Labeled Standards ILM003 U-[ 13 C 34 ]-Fumonisin B1 (25 µg/ml) in acetonitrile/water 1.2 ml ILM004 U-[ 13 C 34 ]-Fumonisin B2 (10 µg/ml) in acetonitrile/water 1.2 ml ILM005 U-[ 13 C 34 ]-Fumonisin B3 (10 µg/ml) in acetonitrile/water 1.2 ml Check Sample Materials Fumonisins in Maize 100 g FB1: 270 ± 110 µg/kg; FB2: < 80 µg/kg; FB3: < 80 µg/kg These products represent naturally contaminated materials and have a limited supply. Subsequent products might have different characteristics. AgraQuant ELISA Tests Item No. Quantitation Range Limit of Detection No. of Tests AgraQuant Zearalenone COKAQ ppb 20 ppb 96 COKAQ ppb 20 ppb 48 StarLine Immunoaffinity Columns Item No. Product Format No. of Columns ZearaStar COIAC4004 ZearaStar R 3 ml 25 MycoSep & MultiSep Cleanup Columns Item No. Product Specificity No. of Columns MycoSep MultiSep COCMY2112 MycoSep 112 AflaZon Aflatoxins B1, B2, G1 & G2, Zearalenone, Zearalenol, Zearalanol 25 COCMY2224 MycoSep 224 AflaZon Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMY2226 MycoSep 226 AflaZon+ Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMU2224 MultiSep 224 AflaZon Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMU2226 MultiSep 226 AflaZon+ Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol Calibrant Solutions Zearalenone (ZON) (100 µg/ml) in acetonitrile 5 ml S02029 Zearalenone (ZON) (100 µg/ml) in acetonitrile 1 ml S02041 Zearalanone (ZAN) (10 µg/ml) in acetonitrile 1 ml on request Calibrant Mixtures* MI 4-3-AcDON, DON, NIV, Fus, 5 ml HT-2, T-2, DAS, ZON S02002 MI 4-3-AcDON, DON, NIV, Fus, 1 ml HT-2, T-2, DAS, ZON LMY-093-5ML MI 8 - DON, HT-2, T-2, ZON 5 ml Stable Isotope Labeled Calibrant Mixtures* Page 16 Page 17 ILM ML MI C 15 DON, 13 C 22 HT-2, 13 C 24 T-2, 13 C 18 ZON *composition see page ml on request

10 ZEARALENONE T-2/HT-2 TOIN Solid Standards Zearalenone (99.4 ± 0.6 purity) 5 mg Zearalenone (99.4 ± 0.6 purity) 10 mg Stable Isotope Labeled Standards ILM009 U-[ 13 C 18 ]-Zearalenone (25 µg/ml) in acetonitrile 1.2 ml Check Sample Materials Zearalenone and Deoxynivalenol in Maize 100 g ZON: 79 ± 26 µg/kg, DON: 901 ± 110 µg/kg These products represent naturally contaminated materials and have a limited supply. Subsequent products might have different characteristics. AgraQuant ELISA Tests Item No. Quantitation Range Limit of Detection No. of Tests AgraQuant T-2 Toxin COKAQ ppb 20 ppb 96 COKAQ ppb 20 ppb 48 AgraQuant T-2/HT-2 Toxin COKAQ ppb 29 ppb 96 StarLine Immunoaffinity Columns Item No. Product Format No. of Columns T2/HT2 Star COIAC6004 T2/HT2Star R 3 ml 25 MycoSep & MultiSep Cleanup Columns Item No. Product Specificity No. of Columns MycoSep COCMY2113 MycoSep 113 Trich Trichothecenes, Type A & B 25 COCMY2225 MycoSep 225 Trich 4, 6 Trichothecenes, Type A & B 25 COCMY2227 MycoSep 227 Trich+ 5 Trichothecenes, Type A & B 25 MultiSep COCMU2216 MultiSep 216 Trich Trichothecenes, Type A & B 25 COCMU2225 MultiSep 225 Trich Trichothecenes, Type A & B 25 COCMU2227 MultiSep 227 Trich+ 5 Trichothecenes, Type A & B 25 Page 18 Page 19 4 AOAC Offical Method 5 Japanese Official Method 6 Chinese Quarantine Inspection method

11 T-2/HT-2 TOIN ERGOT ALKALOIDS Calibrant Solutions HT-2 Toxin (100 µg/ml) in acetonitrile 5 ml S02036 HT-2 Toxin (100 µg/ml) in acetonitrile 1 ml T-2 Toxin (100 µg/ml) in acetonitrile 5 ml S02035 T-2 Toxin (100 µg/ml) in acetonitrile 1 ml S02048 T-2 Tetraol (50 µg/ml) in acetonitrile 1 ml on request S02037 T-2 Triol (50 µg/ml) in acetonitrile 1 ml Calibrant Mixtures* MI 4-3-AcDON, DON, NIV, Fus, 5 ml HT-2, T-2, DAS, ZON S02002 MI 4-3-AcDON, DON, NIV, Fus, 1 ml HT-2, T-2, DAS, ZON LMY-093-5mL MI 8 - DON, HT-2, T-2, ZON 5 ml Stable Isotope Labeled Calibrant Mixtures* ILM mL MI C 15 DON, 13 C 22 HT-2, 13 C 24 T-2, 13 C 18 ZON 1.2 ml on request Solid Standards T-2 Toxin (99.7 ± 0.3 purity) 5 mg T-2 Toxin (99.7 ± 0.3 purity) 10 mg Stable Isotope Labeled Standards ILM0008 U-[ 13 C 22 ]-HT-2 Toxin (25 µg/ml) in acetonitrile 1.2 ml U-[ 13 C 24 ]-T-2 Toxin (25 µg/ml) in acetonitrile 1.2 ml MycoSep MycoSep & MultiSep Cleanup Columns Item No. Product Specificity No. of Columns COCMY2150 MycoSep 150 Ergots Ergot Alkaloids 25 Calibrant Solutions LMY-085-5mL Dihydroergocristine (100 µg/ml), dried down Ergocornine (100 µg/ml), dried down 5 ml Ergocorninine (25 µg/ml), dried down 5 ml Ergocristine (100 µg/ml), dried down 5 ml Ergocristinine (25 µg/ml), dried down 5 ml Ergocryptine (100 µg/ml), dried down 5 ml Ergocryptinine (25 µg/ml), dried down 5 ml Ergometrine (100 µg/ml), dried down 5 ml LMY-090-5ML Ergometrinine (25 µg/ml), dried down 5 ml on request 5 ml Ergosine (100 µg/ml), dried down 5 ml LMY-089-5ML Ergosinine (25 µg/ml), dried down 5 ml Ergotamine (100 µg/ml), dried down 5 ml Ergotaminine (25 µg/ml), dried down 5 ml Calibrant Mixtures* MI 6 - Ergot Alkaloids 5 ml Ergocornine, Ergocristine, Ergocryptine, Ergometrine, Ergosine, Ergotamine; 100 µg/ml each, dried down *composition see page 27 Page 20 Page 21 *composition see page 27

12 CLEANUP COLUMNS RAPID TESTS StarLine Immunoaffinity Columns Item No. Product Specificity Format No. of Columns COIAC1001 AflaStar FIT Aflatoxins B1, B2, G1 & G2 1 ml 25 COIAC1004 AflaStar R Aflatoxins B1, B2, G1 & G2 3 ml 25 COIAC1005 AflaStar M1 R Aflatoxin M1 3 ml 25 COIAC1501 AflaStar FIT Aflatoxins B1, B2, G1 & G2 1 ml 500 COIAC1504 AflaStar R Aflatoxins B1, B2, G1 & G2 3 ml 500 COIAC2001 OchraStar FIT Ochratoxin A 1 ml 25 COIAC2004 OchraStar R Ochratoxin A 3 ml 25 COIAC2504 OchraStar R Ochratoxin A 3 ml 500 COIAC3000 FumoniStar Fumonisin B1, B2, B3 3 ml 25 COIAC4004 ZearaStar R Zearalenone 3 ml 25 COIAC5004 DONStar R Deoxynivalenol 3 ml 25 COIAC5504 DONStar R Deoxynivalenol 3 ml 500 COIAC6004 T2/HT2 Star R T2 Toxin HT2 Toxin 3 ml 25 MycoSep & MultiSep Cleanup Columns MycoSep Item No. Product Specificity No. of Columns COCMY2112 MycoSep 112 AflaZon Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMY2113 MycoSep 113 Trich Trichothecenes, Type A & B 25 COCMY2150 MycoSep 150 Ergot Ergot Alkaloids 25 COCMY2224 MycoSep 224 AflaZon 4 Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMY2225 MycoSep 225 Trich 4, 6 Trichothecenes, Type A & B 25 COCMY2226 MycoSep 226 AflaZon+ Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMY2227 MycoSep 227 Trich+ 5 Trichothecenes, Type A & B 25 COCMY2228 MycoSep 228 AflaPat 5 Aflatoxins B1, B2, G1 & G2, Patulin 25 COCMY2229 MycoSep 229 Ochra Ochratoxin A 25 COCMY2230 MycoSep 230 Niv Nivalenol 25 COCMY2231 MycoSep 231 Fum Fumonisin B1, B2 & B3 25 COCMY2240 MycoSep 240 Mon Moniliformin 25 MultiSep COCMU2211 MultiSep 211 Fum Fumonisin B1, B2 & B3 25 COCMU2216 MultiSep 216 Trichothecenes, Type A & B 25 COCMU2224 MultiSep 224 AflaZon Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMU2225 MultiSep 225 Trich Trichothecenes, Type A & B 25 COCMU2226 MultiSep 226 AflaZon+ Aflatoxins B1, B2, G1 & G2, 25 Zearalenone, Zearalenol, Zearalanol COCMU2227 MultiSep 227 Trich+ 5 Trichothecenes, Type A & B 25 COCMU2228 MultiSep 228 AflaPat 5 Aflatoxins B1, B2, G1 & G2, Patulin 25 COCMU2229 MultiSep 229 Ochra Ochratoxin A 25 COCMU2230 MultiSep 230 Niv Nivalenol 25 MycoSpin Column Item No. Product Specificity No. of Columns COCMY2400 MycoSpin 400 Multitoxin Aflatoxin B1, B2, G1 & G2, Trichothecenes Type A & B, 25 Zearalenone, Ochratoxin A 4 AOAC official method 5 Japanese official method 6 Chinese Quarantine Inspection method Page 22 Page 23 AgraQuant ELISA Tests Item No. Product Quantitation Range LOD No. of Tests COKAQ1000 AgraQuant Aflatoxin 4 40 ppb 3 ppb 96 COKAQ1048 AgraQuant Aflatoxin 4 40 ppb 3 ppb 48 COKAQ1100 AgraQuant Aflatoxin ppb 1 ppb 96 COKAQ1148 AgraQuant Aflatoxin ppb 1 ppb 48 COKAQ7100 AgraQuant Aflatoxin M ppt ppb 96 COKAQ7200 AgraQuant Aflatoxin M ppt ppb 96 COKAQ8000 AgraQuant Aflatoxin B ppb 2 ppb 96 COKAQ8048 AgraQuant Aflatoxin B ppb 2 ppb 48 COKAQ2000 AgraQuant Ochratoxin 2 40 ppb 1.9 ppb 96 COKAQ2048 AgraQuant Ochratoxin 2 40 ppb 1.9 ppb 48 COKAQ3000 AgraQuant Fumonisin ppb 200 ppb 96 COKAQ3048 AgraQuant Fumonisin ppb 200 ppb 48 COKAQ4000 AgraQuant Deoxynivalenol ppb 200 ppb 96 COKAQ4048 AgraQuant Deoxynivalenol ppb 200 ppb 48 COKAQ5000 AgraQuant Zearalenone ppb 20 ppb 96 COKAQ5048 AgraQuant Zearalenone ppb 20 ppb 48 COKAQ6000 AgraQuant T-2 Toxin ppb 20 ppb 96 COKAQ6048 AgraQuant T-2 Toxin ppb 20 ppb 48 COKAQ6100 AgraQuant T-2/HT-2 Toxin ppb 29 ppb 96 AgraStrip Lateral Flow Devices Item No. Product Quantitation Range LOD No. of Tests COKAS1100 AgraStrip Aflatoxin 2 cut-off 4 ppb - 24 COKAS1100U AgraStrip Aflatoxin 2 cut-off 4 ppb - 24 COKAS1200 AgraStrip Aflatoxin 1 cut-off 10 ppb - 24 COKAS1200U AgraStrip Aflatoxin 1 cut-off 10 ppb - 24 COKAS1000 AgraStrip Aflatoxin 1 cut-off 20 ppb - 24 COKAS1000U AgraStrip Aflatoxin 1 cut-off 20 ppb - 24 COKAS1600A AgraStrip Aflatoxin ppb 3.6 ppb 24 for AgraVision Reader COKAS4000A AgraStrip DON ppb 300 ppb 24 for AgraVision Reader COKAS3000A AgraStrip FUM ppb 190 ppb 24 for AgraVision Reader FluoroQuant Fluorometry Item No. Product Version LOD No. of Tests COKFA1010 FluoroQuant Afla 1-3 ppb 25 COKFA3070 FluoroQuant Afla Plus 3 acetonitrile from 0.5 ppb 25 COKFA3070D FluoroQuant Afla Plus 3 methanol from 0.6 ppb 25 COKFA4010 FluoroQuant Afla IAC 1 US Domestic Version 3 ppb 25 COKFA4020 FluoroQuant Afla IAC International Version 3 ppb 25 1 USDA/GIPSA approved 2 Japanese Department of Agriculture approved 3 AOAC RI approved

13 REFERENCE MATERIALS REFERENCE MATERIALS Calibrant Solutions LMY-088-1ML 15-Acetoxyscirpenol (50 µg/ml) in acetonitrile 1 ml Acetyl-Deoxynivalenol (15-AcDON) (100 µg/ml) in AcN 5 ml S Acetyl-Deoxynivalenol (15-AcDON) (100 µg/ml) in AcN 1 ml Acetyl-Deoxynivalenol (3-AcDON) (100 µg/ml) in acetonitrile 5 ml S Acetyl-Deoxynivalenol (3-AcDON) (100 µg/ml) in acetonitrile 1 ml Aflatoxin B1 (AFB1) (2 µg/ml) in acetonitrile 5 ml S02017 Aflatoxin B1 (AFB1) (2 µg/ml) in acetonitrile 1 ml Aflatoxin B2 (AFB2) (0.5 µg/ml) in acetonitrile 5 ml S02018 Aflatoxin B2 (AFB2) (0.5 µg/ml) in acetonitrile 1 ml Aflatoxin G1 (AFG1) (2 µg/ml) in acetonitrile 5 ml S02019 Aflatoxin G1 (AFG1) (2 µg/ml) in acetonitrile 1 ml Aflatoxin G2 (AFG2) (0.5 µg/ml) in acetonitrile 5 ml S02020 Aflatoxin G2 (AFG2) (0.5 µg/ml) in acetonitrile 1 ml Aflatoxin M1 (0.5 µg/ml) in acetonitrile 5 ml S02030 Aflatoxin M1 (0.5 µg/ml) in acetonitrile 1 ml Agroclavine (100 µg/ml) in acetonitrile 5 ml on request S02054 Alpha-Zearalanol (Zeranol) (10 µg/ml) in acetonitrile 1 ml S02042 Alpha-Zearalenol (10 µg/ml) in acetonitrile 1 ml S02076 Alternariol (100 µg/ml) in acetonitrile 1 ml S02077 Alternariolmethylether (100 µg/ml) in acetonitrile 1 ml LMY-056-1ML Beauvericin (100 µg/ml) dried down 1 ml on request S02055 Beta-Zearalanol (Taleranol) (10 µg/ml) in acetonitrile 1 ml S02043 Beta-Zearalenol (10 µg/ml) in acetonitrile 1 ml LMY-084-1ML Citreoviridin (100 µg/ml) dried down 1 ml on request S02063 Citrinin (100 µg/ml) in acetonitrile 1 ml on request LMY-095-1mL Cyclopiazonic Acid (100 µg/ml) in acetonitrile 1 ml on request Deepoxy-deoxynivalenol (50 µg/ml) in acetonitrile 5 ml S02033 Deepoxy-deoxynivalenol (50 µg/ml) in acetonitrile 1 ml Deoxynivalenol (DON) (100 µg/ml) in acetonitrile 5 ml S02009 Deoxynivalenol (DON) (100 µg/ml) in acetonitrile 1 ml S02046 Deoxynivalenol-3-glucoside (50 µg/ml) in acetonitrile 1 ml Diacetoxyscirpenol (DAS) (100 µg/ml) in acetonitrile 5 ml S02037 Diacetoxyscirpenol (DAS) (100 µg/ml) in acetonitrile 1 ml S02056 Fumagillin (100 µg/ml) in acetonitrile 1 ml Fumonisin B1 (FB1) (50 µg/ml) in acetonitrile/water 5 ml S02003 Fumonisin B1 (FB1) (50 µg/ml) in acetonitrile/water 1 ml LMY-087-1ML Fumonisin B1, hydrolyzed (HFB1) (25 µg/ml) in /water 1 ml on request Fumonisin B2 (FB2) (50 µg/ml) in acetonitrile/water 5 ml S02004 Fumonisin B2 (FB2) (50 µg/ml) in acetonitrile/water 1 ml S02007 Fumonisin B3 (FB3) (50 µg/ml) in acetonitrile/water 1 ml Fusarenon (Fus) (100 µg/ml) in acetonitrile 5 ml S02010 Fusarenon (Fus) (100 µg/ml) in acetonitrile 1 ml S02057 Gliotoxin (100 µg/ml) in acetonitrile 1 ml on request Page 24 Page 25 Calibrant Solutions HT-2 Toxin (HT-2) (100 µg/ml) in acetonitrile 5 ml S02036 HT-2 Toxin (HT-2) (100 µg/ml) in acetonitrile 1 ml LMY-083-1ML Kojic acid (100 µg/ml) in dried down 1 ml on request LMY-081-1ML Meleagrin (100 µg/ml) in dried down 1 ml on request S02058 Moniliformin (MON) (100 µg/ml) in acetonitrile/water 1 ml Mycophenolic acid (100 µg/ml) in acetonitrile 5 ml on request S02049 Mycophenolic acid (100 µg/ml) in acetonitrile 1 ml on request Neosolaniol (NEO) (100 µg/ml) in acetonitrile 5 ml S02001 Neosolaniol (NEO) (100 µg/ml) in acetonitrile 1 ml Nivalenol (NIV) (100 µg/ml) in acetonitrile 5 ml S02011 Nivalenol (NIV) (100 µg/ml) in acetonitrile 1 ml Ochratoxin A (OTA) (10 µg/ml) in acetonitrile 5 ml S02023 Ochratoxin A (OTA) (10 µg/ml) in acetonitrile 1 ml S02052 Ochratoxin B (OTB) (10 µg/ml) in acetonitrile 1 ml S02053 Ochratoxin-alpha (OTα) (10 µg/ml) in acetonitrile 1 ml Patulin (PAT) (100 µg/ml) in acetonitrile 5 ml S02026 Patulin (PAT) (100 µg/ml) in acetonitrile 1 ml S02059 Paxilline (100 µg/ml) in acetonitrile 1 ml on request S02060 Penicillic acid (100 µg/ml) acetonitrile 1 ml S02079 Roquefortine C (100 µg/ml) dried down 1 ml LMY ML Secalonic Acid D (50 µg/ml) in chloroform 1.2 ml on request LMY-086-1ML Stachybotrylactam (100 µg/ml) dried down 1 ml on request Sterigmatocystin (50 µg/ml) in acetonitrile 5 ml S02051 Sterigmatocystin (50 µg/ml) in acetonitrile 1 ml S02048 T-2 Tetraol (50 µg/ml) in acetonitrile 1 ml on request T-2 Toxin (T-2) (100 µg/ml) in acetonitrile 5 ml S02035 T-2 Toxin (T-2) (100 µg/ml) in acetonitrile 1 ml S02047 T-2 Triol (50 µg/ml) in acetonitrile 1 ml S02078 Tentoxin (100 µg/ml) dried down 1 ml LMY-080-1ML Tenuazonic acid (100 µg/ml) dried down 1 ml S02061 Verruculogen (100 µg/ml) in acetonitrile 1 ml on request S02062 Wortmannin (100 µg/ml) in acetonitrile 1 ml on request S02041 Zearalanone (ZAN) (10 µg/ml) in acetonitrile 1 ml on request Zearalenone (ZON) (100 µg/ml) in acetonitrile 5 ml S02029 Zearalenone (ZON) (100 µg/ml) in acetonitrile 1 ml

14 REFERENCE MATERIALS Ergot Alkaloids LMY-085-5mL Dihydroergocristine 5 ml on request Ergocornine (100 µg/kg) dried down 5 ml Ergocorninine (25 µg/kg) dried down 5 ml Ergocristine (100 µg/kg) dried down 5 ml Ergocristinine (25 µg/kg) dried down 5 ml Ergocryptine (100 µg/kg) dried down 5 ml Ergocryptinine (25 µg/kg) dried down 5 ml Ergometrine (100 µg/kg) dried down 5 ml LMY-090-5ML Ergometrinine (25 µg/kg) dried down 5 ml Ergosine (100 µg/kg) dried down 5 ml LMY-089-5ML Ergosinine (25 µg/kg) dried down 5 ml Ergotamine (100 µg/kg) dried down 5 ml Ergotaminine (25 µg/kg) dried down 5 ml Calibrant Mixtures * MI 1 (Aflatoxins) 5 ml S02021 MI 1 (Aflatoxins) 1 ml MI 2 (B Trichothecenes) 5 ml S02026 MI 2 (B Trichothecenes) 1 ml MI 3 (Fumonisins) 5 ml S02006 MI 3 (Fumonisins) 1 ml MI 4 (A & B Trichothecenes, ZON) 5 ml S02002 MI 4 (A & B Trichothecenes, ZON) 1 ml MI 5 (Aflatoxins) 5 ml S02022 MI 5 (Aflatoxins) 1 ml MI 6 (Ergot Alkaloids) 5 ml LMY-093-5mL MI 8 (Fusarium toxins) 5 ml LMY-092-5mL MI 9 (Aflatoxins) 5 ml REFERENCE MATERIALS Composition of Mycotoxin Calibrant Mixtures MI 1 2 µg/ml Aflatoxin B1, 2 µg/ml Aflatoxin G1, 0.5 µg/ml Aflatoxin B2, 0.5 µg/ml Aflatoxin G2 in acetonitrile MI 2 MI 3 MI µg/ml each of Deoxynivalenol, Nivalenol, 3-Acetyl-deoxynivalenol, 15-Acetyl-deoxynivalenol in acetonitrile 50 µg/ml each Fumonisin B1, Fumonisin B2 in acetonitile/water 10 µg/ml each 3-Acetyl-doxynivalenol, Deoxynivalenol, Nivalenol, Fusarenon, HT-2 Toxin, T-2 Toxin, Diacetoxyscirperiol, Zearalenone in acetonitrile MI µg/ml each Aflatoxin B1, Aflatoxin B2, Aflatoxin G1, Aflatoxin G2 in acetonitrile MI 6 MI µg/ml each Ergocornine, Ergocristine, Ergocryptine, Ergometrine, Ergosine, Ergotamine dried down 100 µg/ml Deoxynivalenol, 100 µg/ml HT-2Toxin, 10 µg/ml T-2 Toxin, 30 µg/ml Zearalenone MI 9 1 µg/ml Aflatoxin B1, 1 µg/ml Aflatoxin B2, 1 µg/ml Aflatoxin G1, 1 µg/ml Aflatoxin G2 in acetonitrile MI µg/ml 13 C 15 Deoxynivalenol, 10 µg/ml 13 C 22 HT-2Toxin, 1 µg/ml 13 C 24 T-2Toxin, 3 µg/ml 13 C 18 Zearalenone in acetonitrile MI µg/ml 13 C 17 Aflatoxin B1, 0.5 µg/ml 13 C 17 Aflatoxin B2, 0.5 µg/ml 13 C 17 Aflatoxin G1, 0.5 µg/ml 13 C 17 Aflatoxin G2 in acetonitrile MI µg/ml 13 C 34 Fumonisin B1, 50 µg/ml 13 C 34 Fumonisin B2 Composition of Mycotoxin Calibrant Kit KIT 1 (LC-MS Mycotoxin Kit) MI 3 (Fumonisins), MI 8 (Fusarium Toxins), MI 9 (Aflatoxins) Ochratoxin A MI 10 ( 13 C Fusarium Toxins), MI 11 ( 13 C Aflatoxins), MI 12 ( 13 C Fumonisins) U-[ 13 C 20 ]-Ochratoxin A (on request) Concentration See items: , LMY-093-5ML, LMY-092-5ML, , ILM ML, ILM ML, ILM ML, ILM007 Stable Isotope Labeled Calibrant Mixtures * ILM mL MI 10 ( 13 C Fusarium toxins) 1.2 ml on request ILM mL MI 11 ( 13 C Aflatoxins) 1.2 ml ILM mL MI 12 ( 13 C Fumonisins) 1.2 ml on request *composition see page 27 Page 26 Page 27

15 REFERENCE MATERIALS REFERENCE MATERIALS Check Sample Materials Solid Standards Acetyldeoxynivalenol (98.8 ± 1.2 purity) 5 mg Acetyldeoxynivalenol (98.8 ± 1.2 purity) 10 mg Acetyldeoxynivalenol (99.4 ± 0.6 purity) 5 mg Acetyldeoxynivalenol (99.4 ± 0.6 purity) 10 mg Aflatoxin B1 (99.5 ± 0.5 purity) 5 mg Aflatoxin B2 (99.7 ± 0.3 purity) 5 mg Aflatoxin G1 (98.0 ± 2.0 purity) 5 mg Aflatoxin G2 (97.1 ± 2.9 purity) 5 mg Deoxynivalenol (99.4 ± 0.6 purity) 5 mg Deoxynivalenol (99.4 ± 0.6 purity) 10 mg Fumonisin B1 (97.6 ± 2.4 purity) 5 mg Fumonisin B1 (97.6 ± 2.4 purity) 10 mg Fusarenon (99.4 ± 0.6 purity) 5 mg Fusarenon (99.4 ± 0.6 purity) 10 mg Neosolaniol (99.4 ± 0.6 purity) 5 mg Neosolaniol (99.4 ± 0.6 purity) 10 mg Nivalenol hydrate (98.6 ± 1.4 purity) 5 mg Nivalenol hydrate (98.6 ± 1.4 purity) 10 mg Ochratoxin A (99.5 ± 0.5 purity) 5 mg Ochratoxin A (99.5 ± 0.5 purity) 10 mg Patulin (99.7 ± 0.3 purity) 5 mg Sterigmatocystin (99.7 ± 0.3 purity) on request T-2 Toxin (99.7 ± 0.3 purity) 5 mg T-2 Toxin (99.7 ± 0.3 purity) 10 mg Zearalenone (99.4 ± 0.6 purity) 5 mg Zearalenone (99.4 ± 0.6 purity) 10 mg Matrix Reference Materials Aflatoxin in Pistachios 55 g Afla B1: 34.0 µg/kg ± 0.9 µg/kg Afla B2: 2.4 µg/kg ± 0.1 µg/kg Afla G1: < 0.1 µg/kg Afla G2: < 0.1 µg/kg Afla total: 36.0 µg/kg ± 1.0 µg/kg Deoxynivalenol in Maize 55 g DON: 1840 ± 30 µg/kg Deoxynivalenol in Wheat 55 g DON: 877 ± 23 µg/kg These products represent naturally contaminated materials and have a limited supply. Subsequent products might have different characteristics. Page 28 Page Fumonisins in Maize 100 g FB1: 270 ± 110 μg/kg; FB2: < 80 μg/kg; FB3: < 80 μg/kg Ochratoxin A in Wheat 100 g OTA 8.6 ± 3.6 µg/kg Zearalenone und Deoxynivalenol in Maize 100 g ZON: 79 ± 26 μg/kg, DON: 901 ± 110 μg/kg Deoxynivalenol in Wheat DON: 1431 ± 265; Sum of 3AcDON and 15AcDON < g Aflatoxin in Maize 100 g Afla B1: 4.06 μg/kg ± 1.05 μg/kg; Afla B2: 0.46 μg/kg ± 0.15 μg/kg; Afla G1:< 0.1 μg/kg; Afla G2: < 0.1 μg/kg; Afla total: 4.52 μg/kg ± 1.20 μg/kg Aflatoxin in Maize 100 g Afla B1: 9.62 μg/kg ± 2.70 μg/kg; Afla B2: 0.74 μg/kg ± 0.26 μg/kg; Afla G1: 0.68 μg/kg ± 0.28 μg/kg; Afla G2: < 0.1 μg/kg ± 0.28 μg/kg; Afla total: μg/kg ± 3.24 μg/kg Stable Isotope Labeled Calibrants ILM006 U-[ 13 C 17 ]-3-Acetyl-Deoxynivalenol (25 µg/ml) in AcN 1.2 ml ILM010 U-[ 13 C 17 ]-Aflatoxin B1 (0.5 µg/ml) in AcN 1.2 ml ILM ML U-[ 13 C 17 ]-Aflatoxin B2 (0.5 µg/ml) in AcN 1.2 ml ILM ML U-[ 13 C 17 ]-Aflatoxin G1 (0.5 µg/ml) in AcN 1.2 ml ILM ML U-[ 13 C 17 ]-Aflatoxin G2 (0.5 µg/ml) in AcN 1.2 ml ILM ML U-[ 13 C 17 ]-Aflatoxin M1 (0.5 µg/ml) in AcN 1.2 ml ILM ML U-[ 13 C 19 ]-Diacetoxyscirpenol (25 µg/ml) in AcN 1.2 ml U-[ 13 C 15 ]-Deoxynivalenol (25 µg/ml) in AcN 1.2 ml ILM003 U-[ 13 C 34 ]-Fumonisin B1 (25 µg/ml) in AcN/water 1.2 ml ILM004 U-[ 13 C 34 ]-Fumonisin B2 (10 µg/ml) in AcN/water 1.2 ml ILM005 U-[ 13 C 34 ]-Fumonisin B3 (10 µg/ml) in AcN/water 1.2 ml ILM008 U-[ 13 C 22 ]-HT-2 Toxin (25 µg/ml) in AcN 1.2 ml ILM ML U-[ 13 C 6 ]-Kojic Acid (25 µg/ml) in AcN 1.2 ml on request ILM007 U-[ 13 C 20 ]-Ochratoxin A (10 µg/ml) in AcN 1.2 ml ILM ML U-[ 13 C 7 ]-Patulin (25 µg/ml) in AcN 1.2 ml ILM ML U-[ 13 C 17 ]-Mycophenolic acid (100 µg/ml) in AcN 1.2 ml on request ILM ML U-[ 13 C 15 ]-Nivalenol (25 µg/ml) in AcN 1.2 ml ILM ML U-[ 13 C 22 ]-Roquefortine C (25 µg/ml) in AcN 1.2 ml on request ILM ML U-[ 13 C 18 ]-Sterigmatocystin (25 µg/ml) in AcN 1.2 ml on request U-[ 13 C 24 ]-T-2 Toxin (25 µg/ml) in AcN 1.2 ml ILM009 U-[ 13 C 18 ]-Zearalenone (25 µg/ml) in AcN 1.2 ml These products represent naturally contaminated materials and have a limited supply. Subsequent products might have different characteristics.

16 Enzymatic FOOD ANALYSIS Enzymatic FOOD ANALYSIS EnzymeFast Tests Item No. Product No. of Assays Sugars COKEF0100 EnzymeFast Lactose/D-Galactose 140 COKEF0200 EnzymeFast Sucrose/D-Glucose/D-Fructose 70 COKEF0300 EnzymeFast Sucrose/D-Glucose 70 COKEF0400 EnzymeFast D-Glucose/D-Fructose 70 COKEF0700 EnzymeFast Lactose/D-Glucose 140 The traditional enzymatic method has now been transferred to a microtitre plate kit format a significant benefit in routine food analysis Enzymatic food analysis is a basic method used for the measurement of compounds such as sugars, acids, alcohols and other metabolites in foods and beverages. In general, enzymes are proteins that catalyze the conversion of one molecule into another. Certain enzymatic reactions lead to color formation or consumption that often takes place in a wavelength range invisible to the human eye. This change in intensity can be measured. The high specificity of enzyme reactions allows for the analysis of food components in complex matrices. Enzymatic methods are especially important for food production and quality assurance. Results give information on the nutrients, authenticity and hygienic status of the food. For example, levels of sugars are crucial for consumers suffering from intolerances and the presence of certain metabolites indicates a lack of hygiene during production. With using enzymatic methods it is also possible to detect whether food has been tampered. Romer Labs offers a growing list of enzymatic test kits for rapid and reliable analysis in a microtitre plate format. Page 30 Page 31

17 Food ALLERGENS Food Allergens RAPID TESTS AgraQuant F.A.S.T. Tests Item No. Product Quantitation Range LOD No. of Tests Eight major food allergens, the so-called Big 8, are responsible for the vast majority of all recorded food allergy incidents. A food allergy is an immune response to a food allergen that the body mistakenly believes is harmful. Food allergies affect 1 3 % of the population as a whole and 5 8 % of children, making them an important health issue in modern society. Even minimal exposure to a food allergen in the milligram range can cause symptoms from mild skin rashes to fatal anaphylactic shocks. Despite the fact that any food could provoke an allergic reaction, the vast majority of documented incidents are caused by cereals containing gluten, crustaceans, eggs, fish, peanuts, soybeans, milk and lactose, in addition to nuts. Other allergens such as mustard, sesame, celery, mollusks and lupines may be of more regional importance. Thus, legislation in many parts of the world requires that these ingredients be labeled on food products independent of their concentration. Allergens might be present as food ingredients, but what is more dangerous is their unexpected appearance via crosscontaminations during the production process. This means testing needs to be done not only by the authorities for labeling compliance, but also by the manufacturer itself for the on-site control of ingredients and finished products. COKAL0748F AgraQuant F.A.S.T. Almond 1 25 ppm 0.5 ppm 48 COKAL1248F AgraQuant F.A.S.T. Casein 1 25 ppm 0.2 ppm 48 COKAL3148F AgraQuant F.A.S.T. Cashew 1 25 ppm 1 ppm 48 COKAL1848F AgraQuant F.A.S.T. Egg 1 25 ppm 0.5 ppm 48 COKAL0348F AgraQuant F.A.S.T. Hazelnut 2 25 ppm 1 ppm 48 COKAL1648F AgraQuant F.A.S.T. Macadamia nut 1 25 ppm 1 ppm 48 COKAL2148F AgraQuant F.A.S.T. Mustard 1 25 ppm 0.5 ppm 48 COKAL0148F AgraQuant F.A.S.T. Peanut 1 25 ppm 0.5 ppm 48 Romer Labs provides an extensive range of allergen test kits for laboratory-based, as well as on-site testing. Page 32 Page 33

18 Food Allergens RAPID TESTS Food Allergens Reference Materials AgraQuant ELISA Tests Item No. Product Quantitation Range LOD No. of Tests COKAL0748 AgraQuant Almond ppm 0.2 ppm 48 COKAL1048 AgraQuant Beta-Lactoglobulin ppb 1.5 ppb 48 COKAL1200 AgraQuant Casein ppm 0.04 ppm 96 COKAL3148 AgraQuant Cashew 2 60 ppm 0.2 ppm 48 COKAL2248 AgraQuant Crustacea ppb 0.9 ppb 48 COKAL0848 AgraQuant Egg White ppm 0.05 ppm 48 COKAL2548 AgraQuant Fish ppm 1.4 ppm 48 COKAL0200 AgraQuant Gluten G ppm 2 ppm 96 COKAL0248 AgraQuant Gluten ppm 0.6 ppm 48 COKAL0348 AgraQuant Hazelnut 1 40 ppm 0.3 ppm 48 COKAL0500 AgraQuant Histamine ppb 0.15 ppb 96 COKAL0548 AgraQuant Histamine rapid ppm 1 ppm 48 COKAL1548 AgraQuant Lupin 2 30 ppm 0.2 ppm 48 COKAL2848 AgraQuant Lysozyme ppb 2 ppb 48 COKAL2448 AgraQuant Milk ppm 0.05 ppm 48 COKAL2148 AgraQuant Mustard 2 60 ppm 1 ppm 48 COKAL2948 AgraQuant Ovalbumine ppb 4 ppb 48 COKAL0148 AgraQuant Peanut 1 40 ppm 0.1 ppm 48 COKAL2748 AgraQuant Pistachio 1 40 ppm 0.13 ppm 48 COKAL1948 AgraQuant Sesame 2 30 ppm 0.2 ppm 48 COKAL0448 AgraQuant Soy ppb 16 ppb 48 COKAL0948 AgraQuant Walnut 2 60 ppm 0.35 ppm 48 Check Sample Materials Positive control sample for Egg 5 g Positive control sample for Casein 5 g Positive control sample for Peanut 5 g These products represent naturally contaminated materials and have a limited supply. Subsequent products might have different characteristics. Accessory COOLS0120 AgraQuant Allergen Swabbing Kit 20 AgraStrip Lateral Flow Devices Item No. Product No. of Tests COKAL0710AS AgraStrip Almond 10 COKAL1010AS AgraStrip Beta-Lactoglobulin 10 COKAL1710AS AgraStrip Brazil Nut 10 COKAL1210AS AgraStrip Casein 10 COKAL1206AS AgraStrip Wine Extraction Buffer (Casein) - COKAL2210AS AgraStrip Crustacea 10 COKAL1310AS AgraStrip Cashew/Pistachio 10 COKAL2610AS AgraStrip Coconut 10 COKAL1810AS AgraStrip Egg 10 COKAL1806AS AgraStrip Wine Extraction Buffer (Egg) - COKAL0200AS AgraStrip Gluten G12 10 COKAL0210AS AgraStrip Gluten 10 COKAL0310AS AgraStrip Hazelnut 10 COKAL1510AS AgraStrip Lupin 10 COKAL1610AS AgraStrip Macadamia Nut 10 COKAL2410AS AgraStrip Milk 10 COKAL2110AS AgraStrip Mustard Kit 10 COKAL0110AS AgraStrip Peanut 10 COKAL1910AS AgraStrip Sesame 10 COKAL0910AS AgraStrip Walnut 10 COKAL0410AS AgraStrip Soy 10 G12 Antibody: The G12 antibody represents the next generation of gluten testing as it targets toxic peptides that trigger auto-immune reactions in people suffering from celiac disease. It is a monoclonal antibody that was raised against the toxic fragment called 33-mer of the gliadin protein present in gluten. Results obtained from immunochemical test systems based on the G12 antibody should be considered to be closer to the ideal of a food safety test as they establish the important link between celiac disease and detection of the immunotoxic peptides. Page 34 Page 35

19 Food PATHOGENS Food PATHOGENS RapidChek E. coli Item No. Product Quantity RapidChek E. coli O157 Test Kit (no media) 50 Tests RapidChek E. coli O157 Media 500 g RapidChek E. coli O157 Media 5 kg Rapid Chek E. coli O157 Test Kit (no media) 500 Tests RapidChek CONFIRM non-o157 STEC 100 Tests per O-Type A breakdown at any point on the farm-totable spectrum can cause catastrophic harm to the health of consumers and great disruption and economic loss to the food industry Margaret A. Hamburg, M.D., Commissioner of Food and Drugs Foodborne illness is a serious public health concern around the world. Foods can become contaminated with pathogenic bacteria through exposure to animal manure, inadequate processing controls, cross-contamination, and improper storage or cooking. Upon ingestion, pathogenic bacteria secrete toxins which can cause human illness, such as diarrhea, fever, vomiting, and abdominal cramps. In severe cases, hemolytic uremic syndrome and listeriosis can lead to death, especially in infants and the elderly. With the globalization of the food supply it is imperative that food producers test their products for pathogens due to numerous regulatory requirements. Production delays and plant shut-downs, food spoilage, brand protection, and product recalls cost money as well as a company s reputation; therefore, cost-effective, easy-to-use, and accurate testing methods are necessary to ensure safe food is being supplied to the consumer. Romer Labs offers validated food pathogen detection solutions for Escherichia coli O157 and other shigatoxin-producing E. coli, Salmonella spp. (including Salmonella Enteritidis), as well as Listeria spp. in a user-friendly, rapid and accurate, costeffective format. RapidChek Listeria Item No. Product Quantity RapidChek Listeria Test Kit (no media) 45 Tests RapidChek Listeria Environmental System 90 Tests RapidChek Listeria Food System 45 Tests RapidChek Listeria Media System 500 g/10 g RapidChek Listeria F.A.S.T. Test Kit (no media) 45 Tests RapidChek Listeria F.A.S.T. Environmental System 180 Tests RapidChek Listeria F.A.S.T. Media 500 g RapidChek Salmonella Item No. Product Quantity RapidChek SELECT Salmonella Test Kit (no media) 50 Tests RapidChek SELECT Salmonella Food System 100 Tests RapidChek SELECT Salmonella Carcass Rinse System 400 Tests RapidChek SELECT Salmonella Environmental System 400 Tests RapidChek SELECT Salmonella Media System 500 g/10 g/250 ml RapidChek Salmonella Test Kit (no media) 50 Tests RapidChek Salmonella Media 500 g RapidChek Salmonella Enteritidis Item No. Product Quantity RapidChek SELECT Salmonella Enteritidis Environmental Swab System 250 Tests RapidChek SELECT Salmonella Enteritidis Egg Test System 250 Tests RapidChek SELECT Salmonella Enteritidis Test Kit (no media) 50 Tests RapidChek SELECT Salmonella Enteritidis Media System 500 g/10 g/250 ml RapidChek CONFIRM Salmonella Enteritidis 100 Tests Page 36 Page 37 High volume packaging also available

20 Ruminant MEAT & BONE MEAL Ruminant MEAT & BONE MEAL AgraStrip FeedChek Item No. Product Quantity AgraStrip FeedChek Test Kit 20 Tests FeedChek Sample Buffer 600 ml AgraStrip FeedChek Test Strips 20 Tests BSE provides an example of an emerging infectious disease that demonstrates the challenges of policy-making in the face of rapidly changing science and public outrage pushing for action Reference: Hueston, W.D. BSE and variant CJD: Emerging science, public pressure and the vagaries of policy-making. Preventive Veterinary Medicine: 2012 Dec 31. Bovine spongiform encephalopathy (BSE), or mad cow disease, is one of several transmissible spongiform encephalopathies (TSEs) or degenerative neurological diseases caused by abnormal prion protein found in the nervous tissues of infected animals that is known to affect various mammalian species including humans. It is spread through the ingestion of infected animal tissue. Most animal health experts believe that the inadvertent contamination of meat and bone meal (MBM) with infected animal tissue and the subsequent use of this material as a feed supplement contribute to the spread of the disease. As a result, the use of processed animal proteins (PAPs) in animal feeds is regulated in many countries around the world. While feed testing is the only definitive means to certify compliance, regulatory compliance often relies solely on paper certification. Recently, rapid methods have become available for use by regulators to determine compliance during routine inspections. Romer Labs offers a rapid, cost-effective immunochromatographic strip test for use in the field that can detect 0.1 % MBM in animal feedstuffs (including raw materials and finished feeds). Page 38 Page , Romer Labs

21 GMO GMO RAPID TESTS AgraQuant ELISA Tests Item No. Product Trait Range No. of Tests GMOChek According to the UN, the global area of GM crop plantation has grown 80-fold between 1996 and Plants of vital importance to agriculture are often genetically modified by the insertion of foreign DNA material into their DNA sequence, resulting in expressed novel traits that normally would not appear in nature -- typically herbicide tolerance or insect resistance. Seeds harvested from GMO plants will also contain the modification. Current GMO production basically centers on four main crops: soybeans, corn, cotton and oilseed rape. On a global level, GMO crops are cultivated on substantial areas of arable land. Approximately 90 % of all soy available commercially is GMO soy (ca. 80 % of corn, ca. 70 % oilseed rape and almost 50 % of cottonseed). When testing for GMOs, detection is achieved either through the inserted DNA or expressed protein translated from the novel DNA. The inserted DNA and its corresponding protein are found in all the cells of the plant. Thus, the seeds and/or plant tissue material (e.g. leaves) can be used for GMO testing. Testing for the expressed protein can be performed using rapid on-site test kits, such as lateral flow devices (LFD) or ELISA, while the reference method for detecting the DNA itself -- using polymerase chain reaction (PCR) methods -- needs to be done by specialized labs. Romer Labs offers a wide range of rapid tests, based on LFD and ELISA technologies, covering the majority of registered GMO traits found on the market. Page 40 Page AgraQuant Cry1F SeedChek Bt-Cry1F n/a AgraQuant EPSPS SeedChek CP4 EPSPS n/a AgraQuant Vip3A SeedChek Vip3A n/a AgraQuant PMI Plate Seed Check PMI n/a AgraQuant DAS Cry1Ac SeedChek Bt-Cry1Ac n/a AgraQuant Soya Toasted Meal GMOChek CP4 EPSPS % AgraQuant RUR Soya Grain GMOChek CP4 EPSPS % AgraQuant Cry1Ab Maize GMOChek Bt-Cry1Ab % 96 Standards RUR Soya Standards - Full Fat Flour (for flour, meal and grit) RUR Soya Standards - Defatted Flour RUR Soya Standards - Protein Isolate AgraStrip Lateral Flow Devices Item No. Product Trait No. of Tests SeedChek AgraStrip Cry2Ab Bt-Cry2Ab AgraStrip LL Cotton PAT AgraStrip EPSPS EPSPS (Event GA21) AgraStrip Cry1Ac Bt-Cry1Ac AgraStrip PMI PMI AgraStrip RUR CP4 EPSPS AgraStrip Cry3Bb Bt-Cry3Bb AgraStrip Cry34Ab1 Bt-Cry34Ab AgraStrip RUR-HS CP4 EPSPS AgraStrip Triple Trait CP4 EPSPS, 50 Bt-Cry1Ab, Bt-Cry3Bb AgraStrip Cry1F Bt-Cry1F 50 (water extract) - corn AgraStrip Vip Vip3A AgraStrip Cry1Ab Bt-Cry1Ab AgraStrip Cry1F Bt-Cry1F 50 (buffer extract) - cotton AgraStrip LL PAT AgraStrip Dual Trait Cry1F/Cry34 Cry1F, Cry AgraStrip Btk Bt-Cry1Ab, Bt-Cry1Ac AgraStrip BR CP4 EPSPS, Bt-Cry1Ac AgraStrip B2R CP4 EPSPS, 50 Bt-Cry2Ab, Bt-Cry1Ac

22 GMO RAPID TESTS GMO RAPID TESTS AgraStrip Lateral FLow Devices Item No. Product Trait LOD No. of Tests TraitChek AgraStrip RUR-HS Bulk Grain CP4 EPSPS % in corn % in canola % in alfalfa AgraStrip RUR Bulk Grain CP4 EPSPS 0.1 % in soy and 100 sugarbeets in 5 min; % in soy in 3 min AgraStrip RUR Seed and Leaf CP4 EPSPS qualitative AgraStrip Cry1Ab Bulk Grain Bt-Cry1Ab 0.9 % in corn AgraStrip Cry1Ab Seed and Leaf Bt-Cry1Ab qualitative AgraStrip Cry1F Seed and Leaf Bt-Cry1F qualitative AgraStrip Cry3Bb Bulk Grain Bt-Cry3Bb % in corn AgraStrip Cry3Bb Seed and Leaf Bt-Cry3Bb qualitative AgraStrip LL Bulk Grain PAT 0.9 % in corn and 100 sugarbeet, 2 % in canola AgraStrip Cry1Ab/LL Bulk Grain Combo Bt-Cry1Ab, PAT 0.9 % in corn AgraStrip LL Seed and Leaf PAT qualitative AgraStrip LL Bulk Grain for Rice PAT 0.05 % in LLRice % in LLRice AgraStrip Cry1F Bulk Grain Bt-Cry1F 0.9 % in corn 100 (water extract) AgraStrip Triple Trait Seed and Leaf CP4 EPSPS, qualitative 100 Bt-Cry1Ab, Bt-Cry3Bb AgraStrip Cry34Ab1 Bulk Grain Bt-Cry34Ab % in corn AgraStrip Vip Seed and Leaf Vip3A qualitative AgraStrip Vip Bulk Grain Vip3A 0.33 % in corn AgraStrip Cry2Ab Seed and Leaf Trait Check Bt-Cry2Ab qualitative AgraStrip RUR Toasted Meal CP4 EPSPS 0.9% in toasted soy AgraStrip Triple Trait Bulk Grain CP4 EPSPS, 0.5 % in corn, 100 Bt-Cry1Ab, 0.9 % in corn, Bt-Cry3Bb 0.5 % in corn AgraStrip Soy Comb 2 Traits CP4 EPSPS, PAT depends on 20 the trait AgraStrip Corn Comb w/vip3a CP4 EPSPS, depends on 20 PAT, Bt-Cry1Ab, the trait Bt-Cry3Bb1, Bt-Cry1F, Bt-Cry34Ab1, VIP3A AgraStrip Triple Trait Seed and Leaf Comb CP4 EPSPS, qualitative 50 Bt-Cry1Ab, Bt-Cry3Bb AgraStrip Semi quantitative CP4EPSPS, PAT, depends 20 Corn comb Vip 3A, Bt-Cry1Ac, on the trait Bt-Cry3Bb, Br-Cry1F, Bt-Cry34Ab AgraStrip Semi quantitative CP4EPSPS, PAT, depends 20 Corn Comb for Vip 3A, Bt-Cry1Ab, on the trait AgraVision Reader Bt-Cry3Bb, Bt-Cry1F, Bt-Cry34Ab1 Page 42 Page 43 AgraStrip Lateral Flow Devices Item No. Product Trait Range Commodity No. of Tests Semi-quantitative TraitChek AgraStrip RUR-HS Bulk Grain CP4 EPSPS 0.1 to 5.0 % corn 100 and canola AgraStrip RUR Bulk Grain CP4 EPSPS 0.1 to 5.0 % soy AgraStrip Cry3Bb Bulk Grain Bt-Cry3Bb 0.25 to 5.0 % corn AgraStrip LL Bulk Grain PAT 0.5 to 5.0 % corn 100 and canola AgraStrip Cry1F Bulk Grain Bt-Cry1F 0.25 to 5.0 % corn 100 (water extract) AgraStrip Cry34Ab1 Bulk Grain Bt-Cry34Ab to 5.0 % corn AgraStrip Cry1Ac Bulk Grain Bt-Cry1Ac 0.5 to 5% corn AgraStrip Vip Bulk Grain Vip3A 0.1 to 5 % corn AgraStrip Semi quantitative CP4EPSPS, PAT, depends corn 20 Corn comb Vip 3A, Bt-Cry1Ac, on the trait Bt-Cry3Bb, Br-Cry1F, Bt-Cry34Ab AgraStrip Semi quantitative CP4EPSPS, PAT, depends corn 20 Corn Comb for Vip 3A, Bt-Cry1Ab, on the trait AgraVision Reader Bt-Cry3Bb, Bt-Cry1F, Bt-Cry34Ab1

23 Residues & ADULTERANTS Veterinary DRUG RESIDUES In contrast to pesticides, exposure to veterinary drug residues is rather more common, as they are directly injected or fed to the animals. Residues in food and feed are a very heterogeneous group of substances ranging from process contaminants to pesticides, veterinary drugs or even substances added illegally, such as melamine. Veterinary drugs are used in animal production to treat disease, maintain herd and flock health, promote growth, improve meat or otherwise reduce production costs. There is a possibility that residues or their metabolites may appear in the final animalbased foods with their use. Government authorities control the use of veterinary drugs and monitor food for unsafe or prohibited residues. There are a wide variety of regulations in place, with some veterinary drugs allowed in animal products for food production under certain conditions and others banned from use completely. Melamine, widely used in combination with formaldehyde to produce melamine resin and melamine foam for countertops, glues, household goods and flame retardants, has been added to raw milk and feed illegally to give the appearance of higher protein content than the actual level. Melamine itself is non-toxic in low doses, but can cause fatal bladder cancer and kidney stones in combination with other chemicals. AgraQuant ELISA Tests Item No. Product Quantitation Range LOD No. of Tests COKDA1100 AgraQuant Chloramphenicol ppb ppb* 96 COKDA0200 AgraQuant AMOZ ppb* 0.2 ppb 96 COKDA0300 AgraQuant AOZ ppb* 0.2 ppb 96 COKDA0400 AgraQuant Clenbuterol ppb* ppb* 96 COKDA0500 AgraQuant Ractopamine ppb ppb* 96 COKDA0600 AgraQuant Beta-Agonists ppb* ppb* 96 COKDA0800 AgraQuant Dexamethasone ppb* ppb* 96 COKDA0900 AgraQuant Ciprofloxacin ppb* ppb 96 COKDA1300 AgraQuant Nitrofuran (AHD) ppb ppb* 96 COKDA1200 AgraQuant Quinolones ppb ppb* 96 COKDA1400 AgraQuant Nitrofuran (SEM) ppb ppb 96 COKDA1600 AgraQuant Sulfonamides ppb ppb 96 *depending on matrix Calibrant Solutions ANT-005-5ML Chloramphenicol (100 µg/ml) in acetonitrile 5 ml ANT-004-5ML Cyclosporine A (100 µg/ml) in acetonitrile 5 ml ANT-002-5ML Griseofulvin (100 µg/ml) in acetonitrile 5 ml ANT-007 Tetracycline (2.5 µg/ml) dried down 5 x 1mL ANT-009 Oxytetracycline (2.5 µg/ml) dried down 5 x 1mL Stable Isotope Labeled Calibrants ANT ML U-[ 13 C 11 ]-Chloramphenicol (25 µg/ml) in acetonitrile 1.2 ml ANT ML U-[ 13 C 62 ]-Cyclosporine A (25 µg/ml) in acetonitrile 1.2 ml ANT ML U-[ 13 C 17 ]-Griseofulvin (25 µg/ml) in acetonitrile 1.2 ml ANT-008 U-[ C 22 N 2 ]-Tetracycline (2.5 µg/ml) dried down 5 x 1mL ANT-010 U-[ C 22 N 2 ]-Oxytetracycline (2.5 µg/ml) dried down 5 x 1mL Pyrrolizidine alkaloids, plant toxins widely found in the Asteraceae, Boraginaceae and Fabaceae families, can form toxic compounds when metabolized (e.g. in the liver). Several food products such as milk, honey, eggs and herbal teas, as well as medicinal products and animal feed, have been found contaminated with pyrrolizidine alkaloids. Romer Labs offers ELISA-based test kits, standards and reference materials for residues. Page 44 Page 45

24 Residues OTHER AgraQuant ELISA Tests Item No. Product Quantitation Range LOD No. of Tests Check Sample Survey Melamine COKAQ9300 AgraQuant Melamine 2 50 ppm* 96 COKAQ9400 AgraQuant Melamine Sensitive ppm* ppm* 96 *depending on matrix Calibrant Solutions ALK-001-1ML Atropine (100 µg/ml) dried down 1 ml ALK-003-1ML Scopolamine (100 µg/ml) dried down 1 ml ALK-004-1ML Hyoscyamine (100 µg/ml) dried down 1 ml ALK-002-1ML Monocrotaline (100 µg/ml) dried down 1 ml ALK-005-1ML Retrorsine (50 µg/ml) dried down 1 ml ALK-006-1ML Senecionine (50 µg/ml) dried down 1 ml ALK-008-1ML Seneciophylline (50 µg/ml) dried down 1 ml ALK-007-1ML Senkirkine (50 µg/ml) dried down 1 ml CMT001 Melamine (100 µg/ml) in acetonitrile 5 ml Stable Isotope Labeled Calibrants CMT002 U-[ 13 C 3 ]-Melamine (100 µg/ml) in acetonitrile 1.2 ml Participating in a sample survey, a multi-laboratory study aimed at producing summary statistics, will give you confidence in your own results. Analyzing samples in your own laboratory often raises the question of comparability. How do the results generated compare to other labs using identical samples? The most common way to find out is by taking part in a proficiency testing program or a check sample survey. In such program, participants receive homogenized sample material to be analyzed using in-house laboratory methods. A description of the procedure and the results will be then forwarded to the organizer, following which the results will be compiled and analyzed statistically. Every participant will get a final report, accompanied by an anonymous summary of all results, together with their own individual results. Romer Labs organizes such programs four times a year for mycotoxins and anyone may take part on a worldwide basis. Naturally contaminated material, homogenized and characterized, will be used as samples for the check sample survey. More details on availability and planned rounds, the type of mycotoxins and matrices in the program, as well as examples of reports from previous rounds, can be found on our website ( romerlabs.com) or are available from your local Romer Labs representative or distributor. Page 46 Page 47

25 I S O Analytical SERVICE Analytical SERVICE Analytical Service Well thought-out quality control systems are important, but it is the analytical data that help to make decisions for fulfillment of quality. Thirty years of experience has built confidence and competence in the Romer Labs analytical testing service as a partner for accurate and reliable results. The service operates on a global scale with laboratories in Austria, Singapore, the United Kingdom and the United States. Comprehensive analytical services for mycotoxins, allergens, GMOs, veterinary drug residues and other contaminants that are of key relevance in food and feed safety are available. These services are on offer for a variety of sample matrices, including grains, feed samples, food samples and many others. Reliable and accurate results are established through ISO9100 certification and ISO17025 accreditation, as well as other reference lab certifications and participation in official proficiency testing programs. State-of-the-art equipment allows our highly trained and motivated analysts to use the latest methods and technologies to perform analyses with the highest level of accuracy and minimal turn-around time. Romer Labs is offering Analytical Services in its laboratories in Austria, Singapore, United States and United Kingdom. The following is a list of parameters and their availability in the respective labs. Analyte Austria Singapore USA UK 3-Acetyl DON 15-Acetyl DON Aflatoxin B1, B2, G1,G2 Aflatoxin M1 Citrinin Cyclopiazonic Acid DAS DON Ergot Alkaloids (Ergocornin, Ergocorninine, Ergocristine, Ergocristinine, Ergocryptin, Ergocryptinine, Ergometrin, Ergometrinine, Ergosin, Ergosinine, Ergotamin, Ergotaminine) Ergocornine Ergocristin Ergocryptin Ergosin Ergotamin Fumonisin B1, B2, B3 Fusarenon HT-2 Toxin Moniliformin Multi-Mycotoxin (18-type) analysis using LC-MSMS Neosolaniol Nivalenol Ochratoxin A Patulin Sterigmatocystin T-2 Toxin Trichothecenes A (Neosolaniol, DAS, T-2 Toxin, HT-2 Toxin) Trichothecenes B (DON, 3-Acetyl-DON, 15-Acetyl-DON, Nivalenol, Fusarenon ) Zearalenone IS O Page 48 Page 49

26 Analytical SERVICE Analytical SERVICE Analytical Service Analyte Austria Singapore USA UK Contaminants Ammelide Ammeline Cyanuric Acid Melamine Food Allergens Almonds BLG (ß-Lactoglobulin) Brazil Nut Casein Cashew Celery Crustacea Egg White Gluten Hazelnuts Histamine Lactose Lupin Milk Mustard Peanuts Pistachio Sesame Soy Walnut Drug Residues Beta-Agonist Chloramphenicol Clenbuterol Nitrofuran Ractopamine Chloramphenicol AMOZ AOZ Clenbuterol Ractopamine Beta-Agonists Dexamethasone Ciprofloxacin Nitrofuran (AHD) Nitrofuran (SEM) Sufonamides Analytical Service Analyte Austria Singapore USA UK GMOs Roundup Ready Soy Bt-11 Maize Bt-176 Maize GA21 Maize MON810 Maize NK603 Maize Star Link Maize T25 (Liberty Link) Maize MON863 Maize E3272 Maize DP98140 Maize Mon Maize Mon Maize Bt-10 Maize TC1507 (Herculex) Maize MON89788 Soy DP Soy DP Soy BPS-CV127-9 Soy A Soy Mon Mon Mon RT73 Rapeseed T45 Rapeseed BT63 Rice LL601 Rice LL62 rice FP967 Lineseed EH Potato GMO Screening Speciation Beef Pork Chicken Turkey Sheep Cod Horse Duck Goat Pesticide Screening Carbamates DithioCarbamates Organochlorus(OC) Organophosporus (OP) Pyrethroids Page 50 Page 51 For further details, please contact Romer Labs sales or the respective lab. Romer Labs Inc. in Union, MO, USA - labusa@romerlabs.com Romer Labs Diagnostic GmbH. in Tulln, Austria - Quantas Analytik - labat@romerlabs.com Romer Labs Singapore Pte. Ltd, Singapore - salesasia@romerlabs.com Romer Labs UK Ltd. in Runcorn, Cheshire, UK - enquiry@romerlabs.com

27 Equipment Equipment Item No. Romer Mills Description Laboratory Equipment High quality equipment is essential to obtain accurate analytical results. When performing an analytical test, strong focus has to be put on the equipment used to obtain accurate and reproducible test results. The first step of any analysis is the use of a well-established sampling plan to obtain a representative sample. After taking the representative sample for instance, consisting mostly of several aggregated subsamples taken out of a large storage tank appropriate sample preparation is vital. This lab sample needs to contain the same concentration of the analyte as the sample from which it was taken. To achieve this goal, two steps are required. First, the representative sample needs to be ground and then a small analytical sample needs to be taken. This is done by using equipment such as mills and/or subsampling devices. Romer Labs offers a range of equipment for such analytical purposes, including Romer Mills for grinding and sample division and the Romer Evap System for the rapid concentration of sample extracts. Furthermore, quantitative and/or semiquantitative analyses often require additional equipment for result interpretation. For instance, Romer Labs offers the AgraVision for lateral flow test interpretation and StatFax or ChroMate from Awareness Technology, Inc. for ELISA quantification purposes. Last but not least, aflatoxin analysis by HPLC-FLD requires derivatization of the analytes for higher sensitivity; a task made possible by Romer Labs photo chemical or electrochemical derivatization units. Page 52 Page 53 Reader Romer Series II Mill 7 EQMMS2010 Series II Mill, 115V EQMMS2015 Series II Mill, 230V, American Plug EQMMS2018 Series II Mill, 230V, European Plug The patented Romer Series II Mill can prepare a representative sample quickly and easily. A 2 lb. (1 kg) sample of corn can be ground and subsampled within 1 to 2 minutes. This mill simultaneously grinds and splits the samples and is the only mill available that combines these two steps into one piece of equipment. The Series II Mill is USDA/GIPSA approved and is used mainly for grains, feeds and foods. RAS (Romer Analytical Sampling) Mill 7 EQMMR1010 RAS Mill, 115V EQMMR1017 RAS Mill, 230V The RAS Mill has been specifically developed for products that are difficult to grind due to high moisture and/or high oil content. Among these products are cottonseed, tree nuts, peanuts and pistachios. A 2 lb. (1 kg) sample of corn can be ground and subsampled in 1 minute. Special features include the availability of 2 unique chute options (to allow more rapid and accurate grinding and sampling), interchangable grinding burrs, and power drive screws to allow the grinding of practically any product. The moving parts are made of stainless steel and flashed chrome for food safety analyses. The RAS Mill is ideal for use in all labs where grinding and subsampling is essential, from pesticides to mycotoxins, moisture and proteins. StatFax ELISA Reader (Awareness Technology, Inc.) EQOLE1409 Stat Fax 303 ELISA Reader The StatFax ELISA Reader is a microstrip reader intended for in-vitro diagnostic use. It is a compact, microprocessor-controlled, photometer system designed to read and calculate the results of endpoint colorimetric assays, which are read in microtiter strips. All AgraQuant ELISA test kits featuring breakaway strips can be read by a Statfax ELISA Reader. ELx800 UV Reader (BioTek Instruments Inc.) EQOLE1495 BioTek ELx800 UV Absorbance Microplate Reader The ELx800 UV is a compact microplate reader that measures in the UV as well as in the visible range. The standard filters 340, 405, 490 and 550 nm are included. It reads 96 well microplates in 30 seconds and comes with Gen5 RC Software. All EnzymeFast Test Kits can be read using the ELx800 UV reader. ChroMate ELISA Reader (Awareness Technology, Inc.) EQOLE1408 ChroMate ELISA Reader The ChroMate ELISA Reader is a compact and economical 8-channel microplate reader, intended for in-vitro diagnostic use. It reads a 96 well plate in 12 seconds and comes with versatile and flexible software. All AgraQuant ELISA test kits can be read with the ChroMate ELISA Reader. 7 AOAC Official Method, USDA/GIPSA approved, UNECE Standard, FAO recommended, OECD recommended