Title : AN301 Rabbit Calici Virus 6 Pages :

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1 Title : AN301 Rabbit Calici Virus 6 Pages : Doc Name : Assists in Protection Last Updated: Protection from Myxomatosis and Calici Virus This product provides a safe and natural protection from virus (spread by agricultural dept.) Can be used for protection or assistance if your rabbits have or could get Calici Virus or Myxomatosis Virus. As well as offering the natural nosode immunizations, we are also providing a natural Myxomatosis solution formulas if your rabbit has this virus already. Australian authorities have approved the virus for use to control "wild" rabbit populations. (RCD) Rabbits Calici Disease. Calici Virus Symptoms in Rabbits. Calici Virus is transferred between animals by flies. The fly lands on a rabbit and the virus is transferred to the new host. Within a few hours, the rabbit feels lethargic. Within 24 hours a major organ of the rabbit hemorrhages and the rabbit dies. In the 18 years since its emergence, it has killed 90% of all rabbits in China and Europe. The virus, RHD (Rabbit Hemorrhagic Disease), is one of the constantly mutating Calici viruses. The Calici virus family (in its many forms), though exhibiting no symptoms, is endemic in the livestock of the US. Diagnosed or symptoms of Rabbit hemorrhagic disease (RHD) Calici Virus (RCS)? * As this year March 2017, yet a third strain of the Calici Virus has been released into land by the Ag Dept Australia wide. What are the Clinical signs of Rabbit Calici Virus (RCD)? The time between the rabbit being infected and the first clinical signs of disease is very short, usually from 12 to 18 hours. Clinical signs are seen as the rabbit becoming quiet and not eating or drinking, quickly leading to death. Death is caused by both cardiac and respiratory failure. Nearly 100% of rabbits that catch the disease die. They die quietly, with little signs of struggling or distress within about 30 hours of being infected. Rabbit hemorrhagic disease (RHD) is caused by the rabbit hemorrhagic disease virus (RHDV), a type of calicivirus which is fatal in poor or weak immune systems of rabbits. This is how the government is trying to kill off wild rabbits Australia wide. Over the past years there have been (2) two strains of this virus in wild rabbit populations in Australia, and now a third one has been released, of this year (early March 2017). Rabbit owners should ensure their rabbits are vaccinated with Cylap vaccine to protect against the original strain of the virus, RHDV1. However, Cylap does not protect against all strains, so additional measures must be taken to reduce the risk of rabbits being exposed to RHDV. 1

2 A few key facts about "calicivirus" in general. FCV infection is common even in healthy pets. Up to 25% of asymptomatic FCV causes extremely variable signs: as noted above, some strains cause no signs at all. Others manifestations of FCV include: mild upper respiratory infection without oral ulceration (indistinguishable from URI due to herpes viral infection); limping with or without URI signs; mild to very severe oral ulceration/ faucitis / ulceration of the esophagus with or without URI signs; systemic signs such as fever, anorexia and lethargy in combination with one or more of the preceding signs; pneumonia; and virulent systemic calicivirus. Not all strains of FCV that cause severe disease are truly virulent systemic FCV. FCV does not always act alone: Even relatively mild field strain FCV in combination with other pathogens most notably Bordetella bronchiseptica and feline panleukopenia can cause severe disease, including pneumonia and death. Not all cases of oral ulceration/uri followed by severe disease and death are VS-FCV! An outbreak of FCV in combination with another pathogen is less of a risk to naïve cats than an outbreak in which FCV acting alone causes severe disease and death. This is because two targets are available for control; panleukopenia is much easier to control than calicivirus because the homeopathic " oral nosodes" is highly effective and there is no carrier state. Last updated: 28 Feb, 2017 Rabbit hemorrhagic disease (RHD) is caused by the rabbit hemorrhagic disease virus (RHDV), a type of calicivirus which is fatal in poor or weak immune systems of rabbits. There are currently two strains of this virus in wild rabbit populations in Australia, with a third has been released in early March Rabbit owners should ensure their rabbits are vaccinated with Cylap vaccine to protect against the original strain of the virus, RHDV1. However, Cylap does not protect against all strains, so additional measures must be taken to reduce the risk of rabbits being exposed to RHDV. Veterinarians should follow current Australian Veterinary Association guidelines to maximize vaccine protection. The Release of RHDV in Australia The first strain of RHDV, known as the Czech strain (belonging to the RHDV1 family), was released by the government in 1996 to help control wild rabbits in an effort to minimize environmental damage being caused. This followed an accidental release of the virus in 1995 from CSIRO field trials on Wardang Island in South Australia. An effective vaccine, Cylap has been available for many years to protect domestic rabbits against this strain of the virus. In recent years, the Czech strain has had less impact on wild rabbit populations due to the development of immunity, so Australian scientists have evaluated a number of different RHDV variants for release. From this evaluation, a new strain was selected known as the Korean strain or K5 (belonging to the RHDV1a family), which is due to be released in early March 2017 at 600 sites across Australia (contact your state department of agriculture for information on locations). This new strain, which was found to be more infectious than the Czech strain, also causes RHD and death in non-immune rabbits. A pilot study to evaluate the effectiveness of the Cylap vaccine against K5 has indicated that this vaccine will provide protection but further trials need to be undertaken to obtain conclusive results. All rabbit owners are advised to ensure their rabbits are vaccinated before K5 is released. RHDV2 outbreaks A third RHDV, known as RHDV2, was first confirmed in a wild rabbit in Canberra in 2015, with authorities unable to state the source of the infection. Over the past eighteen months, it has caused the same type of disease and deaths in wild and domesticated rabbits in NSW, ACT, Victoria, South Australia, Tasmania, Northern Territory and Western Australia. 2

3 No validated trials have been conducted to test the Cylap vaccine against RHDV2 and there are many reports of vaccinated rabbits dying from infection with RHDV2. Thus, all domesticated rabbits, including those who are vaccinated, are at a high risk of becoming ill and dying from RHDV2, if they are exposed to the virus. Young rabbits (3-4 weeks of age) are particularly vulnerable. RHDV2 vaccines being used overseas are not currently available in Australia and they may not be effective against the specific RHDV2 found here. Full protection against RHDV1 (Czech), RHDV1a (K5) and RHDV2 require the development of a 'trivalent' (against three different infectious agents) vaccine using these particular viruses. Research is urgently needed to develop such a vaccine. Overview of RHDV strains Name Type Presence in Australia Czech (original, classic or v351) K5 (Korean) RHDV2 RHDV1 RHDV1a RHDV2 Accidental release in 1995 Controlled release in 1996 Release due in early March 2017 Source unknown. First appeared in ACT in 2015; now reported in NSW, Vic, SA, NT, Tas & WA Disease & death of rabbits Mainly adults as young are more resistant to disease Mainly adults as young are more resistant to disease Very young rabbits most susceptible death likely Vaccination protection with Cylap Yes vaccine provides good protection Pilot study indicates protection* - vaccination is recommended Low# - modified vaccination protocol may provide some protection Note: A small pilot study done in New South Wales showed that all vaccinated rabbits survived infection whereas all unvaccinated rabbits died; however, further research is needed. # Based on many reports of deaths in vaccinated rabbits from outbreaks in several states What are the symptoms of RHDV? RHDV damages internal organs such as the liver and intestines and may cause bleeding. Signs include fever, restlessness, lethargy and poor appetite with bleeding from the nose and/or blood on the floor where rabbits are housed. Often infected rabbits will show no signs and die suddenly. If a pet rabbit is showing signs, a veterinarian should be contacted immediately. There is no remedy for RHD but affected rabbits can be given supportive treatment. 3

4 How does RHDV spread? All RHDV strains can spread easily from infected rabbits in droppings, urine, secretions from the eyes and nose, and at mating. Spread can also occur from contaminated objects such as food, clothing, cages, equipment, insects (especially flies), birds and rodents. The virus can survive in the environment for three and a half months over hotter periods but up to seven and a half months in moderate temperatures. How can I protect my pet rabbit against RHDV? Rabbit owners should ensure their rabbits are vaccinated with Cylap vaccine to protect against RHDV. Veterinarians should follow current AustralianVeterinary Association guidelines to maximise vaccine protection. However, as Cylap does not fully protect against all strains of RHDV, additional measures must be taken to reduce the risk of infection. RHDV1 - an effective vaccine, Cylap has been available for many years to protect rabbits against this strain of the virus. Rabbits must be vaccinated annually to maintain protection against RHDV1. RHDVK5 - the current evidence indicates that vaccination with Cylap will provide protection against RHDVK5, but further research is needed. It is still essential that all rabbits are vaccinated and that precautions are taken to help to prevent infection (see below). RHDV2 - no vaccine is available in Australia that specifically protects against RHDV2. However, a modified vaccination protocol may provide some protection and thus it is still essential that all rabbits are vaccinated and precautions are taken to help to prevent infection (see below). Reducing the risk of RHDV infection RHDV can remain in the environment for an extended period and can be transmitted on objects and via some insects. The following precautions can reduce the risk of infection: Keep your pet rabbit indoors, let out to feed on grass and run around during the day. Rabbit-proof your backyard to prevent access by wild rabbits Regularly decontaminate equipment and materials including cages, hutches, bowls etc, with Colloidal Silver Limit contact between and handling of unfamiliar pet rabbits Decontaminate hands, shoes and clothing after handling other than your own rabbits Control fleas - using Borax powder over the sandy areas of surrounding areas. This kills flea cycle - eggs A Nontoxic toxic and safe way. Control insects (especially flies) as much as possible both indoors and outdoors. Using Essential oils insect repellents. Remove uneaten food on a daily basis.. CONVENTIONAL vaccination injections. Side Effects with the use of any immunologicals or therapeutics, some side effects to vaccination can be expected in a few rabbits. These can include - ~ depression and loss of appetite for a day or so after vaccination. ~ site reactions seen as swellings that can sometimes lead to irritation with patches of hair loss about one week after injection. ~ Death due to anaphylactic reactions or complications with pre-existing disease conditions. The text of this page has been copied direct from a brochure from Fort Dodge Australia. Diagnosed with Rabbit Hemorrhagic Disease (RHD) 4

5 A Natural alternative to boost the immune system. A nosode could be described as an "oral vaccine" in the sense that its purpose is to "immunize" the body against a specific disease. It is prepared from the actual organism which is associated with the disease in question and may derive from filtrates containing only the exotoxins of the bacteria, or from emulsions containing both bacteria and their toxins. These filtrates are then potentised to produce only the energy of the disease and this energy stimulates the entire natural immune system to react against the specific disease. Homeopathic Oral Nosodes are suitable for both humans and their pets. FURTHER INFORMATION of your choice in an alternative method. Nosodes have been used in homeopathic medicine since the mid1800s. Nosodes are relatively unknown in veterinary practice and somewhat controversial in holistic veterinary practice. Many benefits have been noted, including a decrease in the severity and frequency of disease. Although nosodes are still controversial as a replacement for traditional vaccinations, evidence of their safety and efficacy is growing. What are Nosodes? Nosodes are specialized homeopathic remedies that are prepared by taking the actual diseased matter from a sick animal such as diseased tissue or nasal discharge. The preparation of a nosode involves a lengthy process of succussion and dilution of the original material using traditional homeopathic protocols until virtually no molecules of the crude substance remain, rendering the nosode safe for use. This process, called potentization, inactivates the original disease substance and converts the material into a bioenergetic remedy which interacts with the body's energy field. The final product is a potent remedy that is an energetic blueprint of the actual disease. Human Nosode Research Dr. Isaac Golden, an Australian homeopath, has done extensive research in the field of homeopathic childhood immunizations. Working directly with families who agreed to participate in a clinical trial of typical childhood diseases, Dr. Golden concluded that homeopathic immunizations were 90.4% effective.from 2001 to 2004, Dr. Golden also studied vaccine safety compared to homeopathic immunizations. He found that children who received standard vaccines were 15 more times likely to get asthma, 7 times more likely to get eczema and 2 times more likely to get allergies than those who were immunized by homeopathic preparations. His work is published in his ground breaking books, Vaccination, and Homeoprophylaxis: A Review of Risks and Alternatives, and Homeoprophylaxis: A Ten Year Clinical Study Homeopathic Immunization in Dogs Dr. Christopher Day, a British veterinary homeopath, has been using nosodes in his practice for 35 years. Evidence of reduced rates of distemper, hepatitis, leptospirosis, parvovirus and kennel cough has encouraged him to recommend nosodes to his clients for prevention and treatment of disease. In 1985, Dr. Day documented the successful use of nosodes in a kennel cough outbreak. The trial was done in a day care and there were 214 dogs participating, including both vaccinated and unvaccinated dogs. The nosode was introduced by placing it in the dogs drinking water.remarkably, out of a total of 214 dogs that were treated with the kennel cough nosode, the incidence of actual, full-blown disease was only 1.9% out of 214 dogs, and the majority of dogs who did contract kennel cough exhibited only minor symptoms. The vaccinated dogs had a higher incidence of disease at 4.7% whereas only 0.7% of the unvaccinated dogs showed symptoms. Minor symptoms were expressed by 42.5% of the dogs, with 59.7% of vaccinated dogs showing minor symptoms, compared to 26.7% of unvaccinated dogs. This study shows that nosodes can be effective in disease prevention, and when dogs do contract disease, the severity of symptoms can be reduced with their use. A nosode could be described as an "oral vaccine" in the sense that its purpose is to "immunize" the body against a specific disease. It is prepared from the actual organism which is associated with the disease in question and may derive from filtrates containing only the exotoxins of the bacteria, or from emulsions containing both bacteria and their toxins. These filtrates are then potentised a million times to produce the energy only of the disease and this energy stimulates the entire natural immune system to react against a specific disease, so this becomes an oral vaccine for humans as well as pets. The nosodes do not produce a titer response. 5

6 HAMPL Non-Drug Prescriptions - Set of 6 for Rabbit Calici Virus - Treatment & Protection PROTECTION 1. HAMPL Myxo & Calici Virus Oral Nosodes 30ml (1oz) Contains oral viral nosode: Myxomatosis virus oral nosode 30C, 10M with Calici Virus (RCD) oral nosode 30C. A natural immunity against the virus with your pet rabbits. Add 4 drops to the water (filtered) bowl each time you change the water, and stir well. Do this for ongoing if necessary, particularly if exposure to the calici virus is likely. If other pet rabbits have caught the virus, or virus is in area, then I suggest putting drops on the body of each rabbit as well. Repeat daily. Please note: For viral protection of more than one rabbit, add several drops or 2 pills to water (filtered) bowls every time you change it. TREATMENT 2. HAMPL Viral-Bleed 50ml (1.7oz) Contains homeopathic, nosode complex. Support from infection symptoms, anti- bleed, immune support, viral and bacterial infection, flu and gland remedies. 3. HAMPL Viral 11 50ml (1.7oz) Contains homeopathic formula. ~ Support from Acute Viral all symptoms. 4. HAMPL Herb Immune Virus ml (1.7oz) Contains herbal liquid extract concentrate, some of the top anti-viral herbs - Chinese Sculllcap, Houttuynia, Isatis Root, Lomatium. Plus adding IMMUNE BOOSTING herbs with the herbal liquid extract called Codonopsis this herb 1. It regulates gastrointestinal motility, fight against ulcer, and enhance immunity; 2. It affects both excitatory and inhibitory neural processes; 3. Saponins of Codonopsis excite the respiratory center; 4. It lowers the animal blood pressure temporarily but raises the blood pressure on rabbits that are in late hemorrhagic shock; 5. It significantly increases rabbits blood sugar. And rise of serum glucose level is related to the sugar contained; 6. It increases animal erythrocytes, hemoglobin, and reticulocytes; 7. It also delays aging and fights anoxia and radiation. DOSING INSTRUCTIONS PROVIDED Example: Herbal dosing a Rabbit: add 30 drops of the herbal formula into a small bowl (I use an egg cup) adding approx 20ml - 30ml of boiled hot water from the kettle. (this will help dissolve alcohol content - very important) allow to cool. Then add Vitamin C gel from a satchel ) or gel from two capsules (liposomal Vit c does not mix well, will not dissolve, so just stir it before each dosing) Using a small oral syringe, we draw up the liquid and gently inside of mouth squirt small amounts repeating until 2ml- 5ml is taken. Continue three or more a day if lethargic and quite, continue until movement is wellness returns, once this is evident, can reduce the frequency to once to twice a day for as long as required, as prevention also. 5. Liposomal Vitamin C Capsules ( 9 Capsules or 4 Satchels) Ingredients: (ascorbic acid) 1,000mg = 2 caps or 1 Satchel of gel = 1,000mg Other ingredients: sunflower lecithin, medium chain triglycerides, vegetable cellulose, beeswax, paprika extract. *Cut end of cap and squeeze gel into some water or food. Instructions provided SAMPLE supplied. A box of 30 Satchels can be bought on-line from iherb.com 6. Vital Greens Powder (sample satchel) Nutritional powder supplement 6

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