2. Quarterly sales and constant exchange rate sales growth by Division in 2016 and
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1 Appendix: Tables 1. Sales January to March 2016 and Quarterly sales and constant exchange rate sales growth by Division in 2016 and Pharmaceuticals Division Top 20 Pharmaceuticals Division product sales and constant exchange rate growth Q vs. Q Top 20 Pharmaceuticals Division quarterly product sales and quarterly constant exchange rate sales growth Top 20 Pharmaceuticals Division quarterly product sales and quarterly constant exchange rate sales growth United States Top 20 Pharmaceuticals Division quarterly product sales and quarterly constant exchange rate sales growth Europe Top 20 Pharmaceuticals Division quarterly product sales and quarterly constant exchange rate sales growth Japan Top 20 Pharmaceuticals Division quarterly product sales and quarterly constant exchange rate sales growth International*... 10
2 1. Sales January to March 2016 and 2015 Three months ended CHF millions 31 March % change At CER In CHF Pharmaceuticals Division 9,800 9, United States 4,716 4, Europe 2,319 2, Japan International* 1,912 1, Diagnostics Division 2,614 2, Roche Group 12,414 11, * Asia Pacific, EEMEA (Eastern Europe, Middle East and Africa), Latin America, Canada, Others
3 2. Quarterly sales and constant exchange rate sales growth by Division in 2016 and 2015 CHF millions Q vs. Q vs. Q vs. Q vs. Q vs. Pharmaceuticals Division 9, , , , ,800 4 United States 4, , , , ,716 3 Europe 2, , , , ,319 5 Japan International* 1, , , , ,912 4 Diagnostics Division 2, , , , ,614 5 Roche Group 11, , , , ,414 4 *Asia Pacific, EEMEA (Eastern Europe, Middle East and Africa), Latin America, Canada, Others
4 3. Pharmaceuticals Division Top-selling pharmaceuticals and recent new launches Total United States Europe Japan International* January - March 2016 CHF m % CHF m % CHF m % CHF m % CHF m % MabThera/Rituxan 1, Herceptin 1, Avastin 1, Perjeta Actemra/RoActemra Tamiflu Xolair Lucentis Activase/TNKase Tarceva Recent new launches Kadcyla Esbriet Zelboraf Erivedge Gazyva/Gazyvaro Alecensa ** Cotellic 11 ** 2 ** 9 ** * Asia Pacific, EEMEA (Eastern Europe, Middle East and Africa), Latin America, Canada, Others ** Over 500%
5 4. Top 20 Pharmaceuticals Division product sales and constant exchange rate growth Q vs. Q CHF millions Total United States Europe Japan International* CHF m % CHF m % CHF m % CHF m % CHF m % MabThera/Rituxan 1, Herceptin 1, Avastin 1, Perjeta Actemra/RoActemra Tamiflu Xolair Lucentis Activase/TNKase Tarceva Kadcyla CellCept Esbriet Pulmozyme Mircera Xeloda Rocephin Pegasys NeoRecormon/Epogin Valcyte/Cymevene * Asia Pacific, EEMEA (Eastern Europe, Middle East and Africa), Latin America, Canada, Others
6 5. Top 20 Pharmaceuticals Division quarterly product sales and quarterly constant exchange rate sales growth CHF millions Q vs. Q vs. Q vs. Q vs. Q vs. MabThera/Rituxan 1, , , , ,825 3 Herceptin 1, , , , ,725 4 Avastin 1, , , , ,706 4 Perjeta Actemra/RoActemra Tamiflu Xolair Lucentis Activase/TNKase Tarceva Kadcyla CellCept Esbriet Pulmozyme Mircera Xeloda Rocephin Pegasys NeoRecormon/Epogin Valcyte/Cymevene
7 6. Top 20 Pharmaceuticals Division quarterly product sales and quarterly constant exchange rate sales growth United States CHF millions Q vs. Q vs. Q vs. Q vs. Q vs. MabThera/Rituxan Herceptin Avastin Perjeta Actemra/RoActemra Tamiflu Xolair Lucentis Activase/TNKase Tarceva Kadcyla CellCept Esbriet * Pulmozyme Mircera Xeloda Rocephin Pegasys NeoRecormon/Epogin Valcyte/Cymevene * Over 500%
8 7. Top 20 Pharmaceuticals Division quarterly product sales and quarterly constant exchange rate sales growth Europe CHF millions Q vs. Q vs. Q vs. Q vs. Q vs. MabThera/Rituxan Herceptin Avastin Perjeta Actemra/RoActemra Tamiflu Xolair Lucentis Activase/TNKase Tarceva Kadcyla CellCept Esbriet Pulmozyme Mircera Xeloda Rocephin Pegasys NeoRecormon/Epogin Valcyte/Cymevene
9 8. Top 20 Pharmaceuticals Division quarterly product sales and quarterly constant exchange rate sales growth Japan CHF millions Q vs. Q vs. Q vs. Q vs. Q vs. MabThera/Rituxan Herceptin Avastin Perjeta Actemra/RoActemra Tamiflu Xolair Lucentis Activase/TNKase Tarceva Kadcyla CellCept Esbriet Pulmozyme Mircera Xeloda Rocephin Pegasys NeoRecormon/Epogin Valcyte/Cymevene
10 9. Top 20 Pharmaceuticals Division quarterly product sales and quarterly constant exchange rate sales growth International* CHF millions Q vs. Q vs. Q vs. Q vs. Q vs. MabThera/Rituxan Herceptin Avastin Perjeta Actemra/RoActemra Tamiflu Xolair Lucentis Activase/TNKase Tarceva Kadcyla CellCept Esbriet Pulmozyme Mircera Xeloda Rocephin Pegasys NeoRecormon/Epogin Valcyte/Cymevene * Asia Pacific, EEMEA (Eastern Europe, Middle East and Africa), Latin America, Canada, Others
January March CHF m CHF m In CHF
1. Sales January to March 2011 and 2010 2011 2010 % change January March CHF m CHF m In CHF In local currencies Pharmaceuticals Division 8,712 9,727-10 -2 United States 3,322 3,647-9 +2 Western Europe
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Sales CHF millions As % of sales % change. In CHF Group sales 12,942 12,
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Nine months ended 30 September At CER* In CHF In USD Pharmaceuticals Division Excluding Tamiflu 24,397 24,096 28,395 27,587
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1 Pharmaceutical Division 42, Diagnostics Division 32,794 9,737
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