The International Graduate School GRK1409. Molecular Interactions of Pathogens with Biotic and Abiotic Surfaces
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1 The International Graduate School GRK1409 Molecular Interactions of Pathogens with Biotic and Abiotic Surfaces Speakers Hans C. Bauer Kenneth W. Bayles John C. Bell Maurizio Brigotti Petra Dersch Alain Filloux Julia S. Frick Jürgen Heesemann Brendan Kenny Hans-Dieter Klenk Wilhelm Schäfer D. Barry Scott Magdalene So Beate Sodeik Susann Teneberg Ulrich Vogel Salzburg, Austria Omaha, USA Ottawa, Canada Bologna, Italy Braunschweig, Germany London, England Tübingen, Germany München, Germany Newcastle, England Marburg, Germany Hamburg, Germany Palmerston, New Zealand Tucson, USA Hannover, Germany Gothenburg, Sweden Würzburg, Germany Open Lectures! For more information visit the website or contact us: Mail: The International Graduate School GRK1409 Center for Molecular Biology of Inflammation (ZMBE), Von-Esmarch-Str. 56, D Münster
2 II. Summer School Pathogen Host Interactions at Cellular Barriers Scientific Program Jürgen Heesemann Maurizio Brigotti Brendan Kenny Bacteria-Host Interactions (3:00 p.m. 5:25 p.m.) Phagocyte - Staphylococcus interaction in 3-dimensional collagen gels The interaction between Shiga toxins and neutrophils in the pathogenesis of hemolytic uremic syndrome Enteropathogenic E. coli (EPEC) pathogenicity: recent insights on the cooperative and regulated nature of its effector proteins Alain Filloux Kenneth W. Bayles Ulrich Vogel Biofilms (9:00 a.m. 11:15 p.m.) Pseudomonas aeruginosa pathogenesis: molecular switches drive the transition towards the biofilm mode Staphylococcal biofilm formation: a matter of life or death Meningococcal biofilm formation: the role of DNA and altered protein expression Petra Dersch Susann Teneberg Magdalene So Hans C. Bauer Julia S. Frick Bacteria vs. Cellular Barriers (11:45 a.m. 6:05 p.m.) Different strategies controlling host cell invasion by enteropathogenic yersiniae during infection Carbohydrate receptors for microbial pathogens Pulling on the host membrane: how Neisseria gonorrhoeae modulates infection Barriers in the brain: molecular architecture and functions of tight junctions Host microbe interaction in intestinal inflammatory diseases Fungi-Plant Interactions (09:00 a.m. 10:35 a.m.) D. Barry Scott Signalling in the Epichloe festucae - perennial ryegrass mutualistic symbiotic association Wilhelm Schäfer Induction of fungal toxin production by the infected host plant Beate Sodeik John C. Bell Hans-Dieter Klenk Viruses and the Cell (11:05 a.m. 3:20 p.m.) Herpes simplex virus - A hitch hiker's guide to the cell Experimental and clinical studies with oncolytic vaccinia virus Determinants of pathogenicity and host range of influenza viruses Additionally there will be students talks and poster sessions. To check complete program and further information please visit: With great thanks to our supporters:
3 Wednesday, June 8th, :00 Registration 15:00 Welcome Session 1: Bacteria-Host Interactions 15:10 Keynote speaker: Jürgen Heesemann (München, Germany) Phagocyte Staphylococcus interaction in 3-dimensional collagen gels (abstract p. 19, O.01) 15:50 Maurizio Brigotti (Bologna, Italy) The interaction between Shiga toxins and neutrophils in the pathogenesis of hemolytic uremic syndrome (abstract p. 19, O.02) 16:30 Jessica Kneidl (Münster, Germany) CD163 Promotes Recognition, Phagocytosis and Killing of Staphyloccoccus aureus Via Binding of Specific Fibronectin Peptides (abstract p. 20, O.03) 16:45 Brendan Kenny (NewCastle, UK) Enteropathogenic E. coli (EPEC) pathogenicity: recent in sights on the cooperative and regulated nature of its effector proteins (abstract p. 21, O.04) 17:25 Poster Session 1 with sandwiches, beer and wine 14
4 Thursday, June 9th, 2011 Session 2: Biofilms 09:00 Alain Filloux (London, UK) Pseudomonas aeruginosa pathogenesis: molecular switches drive the transition towards the biofilm mode (abstract p. 21, O.05) 09:40 Katja Crull (Braunschweig, Germany) Biofilm formation by Salmonella enterica serovar Typhimurium colonizing solid tumors (abstract p. 22, O.06) 09:55 Kenneth W. Bayles (Omaha, NE, USA) Staphylococcal biofilm formation: a matter of life or death (abstract p. 23, O.07) 10:35 Ulrich Vogel (Würzburg, Germany) In vitro biofilm formation as a model for meningococcal carriage and transmission (abstract p. 23, O.08) 11:15 Coffee Break Session 3: Bacteria vs. Cellular Barriers 11:45 Petra Dersch (Braunschweig, Germany) Different strategies controlling host cell invasion by entero pathogenic yersiniae during infection (abstract p. 24, O.09) 15
5 12:25 Dina Hilmi (Heidelberg, Germany) Differences in Toll-like receptor-2 activity of clinical S. aureus isolates reveal a novel immune evasion strategy (abstract p. 25, O.10) 12:40 Lunch Break 14:10 Susann Teneberg (Gothenburg, Sweden) Carbohydrate receptors for microbial pathogens (abstract p. 25, O.11) 14:50 Magdalena So (Tucson, AZ, USA) Pulling on the Epithelial Cell by Neisseria gonorrhoeae: Consequences for Host and Pathogen (abstract p. 26, O.12) 15:30 Hans C. Bauer (Salzburg, Austria) Barriers in the brain: molecular architecture and functions of tight junctions (abstract p. 27, O.13) 16:10 Poster Session 2 with Coffee 17:10 Roland Bücker (Berlin, Germany) Aerolysin, a pore-forming toxin from Aeromonas hydrophila, disturbs tight junction integrity and epithelial restitution (abstract p. 27, O.14) 17:25 Julia S. Frick (Tübingen, Germany) Host microbe interaction in intestinal inflammatory diseases (abstract p. 28, O.15) 19:00 16
6 Friday, June 10th, 2011 Session 4: Fungi-Plant Interactions 09:00 Barry Scott (Palmerston, New Zealand) Signalling in the Epichloe festucae perennial ryegrass mutualistic symbiotic association (abstract p. 29, O.16) 09:40 Wilhelm Schäfer (Hamburg, Germany) Induction of fungal toxin production by the infected host plant (abstract p. 30, O.17) 10:20 Julia Schumacher (Münster, Germany) Signalling in the plant pathogenic fungus Botrytis cinerea (abstract p. 30, O.18) 10:35 Coffee Break Session 5: Viruses and the Cell 11:05 Beate Sodeik (Hannover, Germany) Herpes simplex virus A hitch hiker s guide to the cell (abstract p. 31, O.19) 11:45 Eike-Roman Hrincius (Münster, Germany) Crk adaptor protein expression is required for efficient repli cation of avian influenza A viruses and controls JNK mediated apoptotic responses (abstract p. 32, O.20) 12:00 John C. Bell (Ottawa, Canada) Experimental and clinical studies with oncolytic vaccinia virus (abstract p. 32, O.21) 12:40 Lunch Break 17
7 14:10 Susanne Weber (Münster, Germany) Human Papillomavirus Type 16 entry into host cells depends on cell cycle progression (abstract p. 33, O.22) 14:25 Meike Müller (Würzburg, Germany) Therapy of human liver tumor xenografts in mice using the recombinant oncolytic vaccinia virus GLV-1h68 (abstract p. 34, O.23) 14:40 Hans-Dieter Klenk (Marburg, Germany) Determinants of pathogenicity and host range of influenza viruses 15:20 Coffee Break (abstract p. 34, O.24) 18
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