Peri-implant marginal bone loss: What is the current concensus? an academic controversy or a clinical challenge?

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1 Peri-implant marginal bone loss; What is the current concensus? Peri-implant marginal bone loss: an academic controversy or a clinical challenge? Björn Klinge Eur J Oral Implantol 2012;5 (Suppl) 1

2 Periimplant tissue destruction Academic controversy: Clinical feature or Initiation of event? 2

3 (Selected) factors related to marginal bone loss: Overloading Bone quality and quantity Trauma to the periosteum Too deep implant placement Implant placed too close to teeth or implants Surgical technique (1 vs 2-stage) Immediate or delayed loading Over-heating during drilling Injury caused by squeezing the bone bed Implant surface structure Different abutment systems (incl platform switching) Biological width Lack of buccal bone Misalignment of the implant One-piece vs two-piece implants Excess implant remnants Inadequate restoration-abutment seating Factors related to marginal bone loss Biofilm accumulation ( infection ) at the implant-tissue interface inflammation tissue destruction, periimplantitis 3

4 The impac of genotypes and immune reactivity in peri-implant inflammation: identification and therapeutic use of antiinflammatory drugs and immunomodulators Thomas E Van Dyke Eur J Oral Implantol 2012; 5 (Suppl) Impact of the type and configuration of abutments and their (repeated) removal on the attachment level and marginal bone Eric Rompen European Journal of Oral Implantology 2012; 5 (suppl) Identifying occlusal overload and how to deal with it to avoid marginal bone loss around implants Jia-Hui Fu, Yung-Ting Hsu, Hom-Lay Wang Eur J Oral Implantol 2012; 5 (Suppl 5) 4

5 Little do we know. World Market Dental Implants # ESTIMATED FIGURES Klinge 2013, NQRDI, Sweden 5

6 Periimplantitis # Estimated growth 25 PubMed Publications Review: Periodontitis AND Dental implants AND Review Human: Periodontitis AND Dental implants AND Human Review Human #REF! PubMed searchoctober 6, 2012 PubMed periimplantitisand human Klinge B., E J Oral Impl

7 Under-reporting of relevant data In a systematic review reporting on complications after > 5 years follow-up, biological complications were reported only in < 40% of all available studies. Berglundh T, Abrahamsson I, Klinge B, J Clin Per 2002 Awareness of the problem (sic!) 7

8 28 % of all patients >1 implant, boneloss > 3 threads Bone gain (+) Thread 0 0: Baseline Thread 1 Thread 2 Thread 3 Distance 0.6mm Bone loss (-) Fransson et al % of patients >1 implant, boneloss > 3 threads Probing Pocket Depth (PPD) > 6mm Bone gain (+) Thread 0 0: Baseline Thread 1 Thread 2 Thread 3 Distance 0.6mm Bone loss (-) Roos Jansåker et al 2006 Peri-implant mucositis was diagnosed at 80% of all investigated individuals and at 50% of all implants Zitzmann et al

9 Peri-implantitis lesions were identified in 28% - >56% of all investigated individuals and at 12% - 43% of all implants Zitzmann et al 2008 Clinical Implant Dentistry and Related Research 2008 Åstrand et al Clinical Impl Dent and Rel Res

10 Åstrand et al Clinical Impl Dent and Rel Res 2008 Peri-implantitis 2.4% (implants, 3/123) 14% (patients, 3/21) Åstrand et al Clinical Impl Dent and Rel Res % of patients PPD > 4mm + BoP Boneloss > 2 mm > 2 mm Koldsland et al et al

11 11.3 % of patients PPD > 6mm + BoP Boneloss > 3 mm > 3 mm Koldsland et al et al % of patients PPD > 6mm + BoP Boneloss > 3 mm 24 % of patients PPD > 4mm + BoP Boneloss > 2 mm > 3 mm > 2 mm Koldsland et al et al

12 Statement 1* The prevalence of peri-implantitis over a 5 to 10 year period following implant placement has been reported to be in the order of 10% of implants and 20% of patients. *Minority statement by T. Albrektsson & A. Wennerberg:..it is quite clear that a particular figure for the true incidence of peri-implantitis cannot be stated.. Klinge B & Meyle J. COIR 2012 Statement 1 Clinical recommendations Peri-implantitis is expected to occur in 1 of 5 patients, hence frequent monitoring of the peri-implant tissues for signs of inflammation is necessary. Prior to placement of implants patients should be informed of the risk of peri-implant diseases and how it can be reduced. 12

13 Little do we know. Levignac J L ostéolyse périimplantaire, périimplantose periimplantite. Rev Fr Odontostomatolol 1965; 12: it is suggested that periimplantitis be regarded as a site specific infection.. 13

14 .failures, even one year after installation, still seemed to be concentrated in patients with a high degree of plaque accumulation. van Steenberghe et al

15 Klinge et al 2005 Klinge et al

16 Klinge et al 2005 Klinge et al 2005 Klinge et al

17 Little do we know. 17

18 World Market Dental Implants # ESTIMATED FIGURES Mio sale Accumul #REF! Periimplantitis # Estimated growth Periimpl 3% Periimpl 10% #REF!

19 Statement Factors that have been shown to affect peri-implantitis prevalence include smoking, poor oral hygiene and a history of periodontitis. Clinical significance Patients presenting with these factors should be subject to high vigilance monitoring. 19

20 20

21 21

22 What have we learned Periodontitis is a risk factor for implant treatment Common (other) risk factors has been identified for periodontitis susceptible individuals and patients experiencing complications in relation to implant treatment. Klinge B & Meyle J, EAO Concensus Conference Clin Oral Implants Research 2012 What have we learned Smokers with previous or current sensitivity to periodontitis have recently been identified as high-risk individuals. Klinge B & Meyle J, EAO Concensus Conference Clin Oral Implants Research

23 What have we learned Patients in general, and periodontitissusceptible individuals in particular, should be kept on a strict oral hygiene maintenance program and be encouraged to quit smoking. Klinge B & Meyle J, EAO Concensus Conference Clin Oral Implants Research 2012 What have we learned Periodontitis-susceptible individuals can be successfully treated with osseointegrated implants, however the patients should be informed of the higher risk involved. Klinge B & Meyle J, EAO Concensus Conference Clin Oral Implants Research

24 Acknowledgment: Dr Hadar Hallström, Halmstad Sweden Dr Margareta Hultin, Stockholm, Sweden Dr Leif Jansson, Stockholm, Sweden Dr Nils Ravald, Linköping, Sweden Dr Christer Slotte, Jönköping, Sweden Dr Andreas Stavropoulos, Malmö, Sweden 71 Peri-implant marginal bone loss; What is the current concensus? 24

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