NVB PRO-CON DEBAT 2018 Er is geen reden voor 1:1:1 -transfusiebeleid of transfusiepaketten in de behandeling van massaal bloedverlies.
|
|
|
- Josephine Rich
- 5 years ago
- Views:
Transcription
1 NVB PRO-CON DEBAT 2018 Er is geen reden voor 1:1:1 -transfusiebeleid of transfusiepaketten in de behandeling van massaal bloedverlies Standpunt: CON Military Blood Bank Dr. F.Noorman Head Quality Research and Development
2 PRO 1:1:1, PRO availability When suspect class III/IV hemorrhage ( 1.5L/5L) ASAP: Start with 2-4 RBC and 2 Plasma Then (if needed) followed by packages: 1 Platelet unit in plasma 3 Plasma 4 RBC 2 After hemodynamic stability achieved: Sample laboratory based transfusion
3 Water is to fish, what blood is to humans.. Traumatic to be without it for seconds 3
4 Resuscitation..The sooner the better! Stop the bleeding Prevent/Treat ASAP: Hypovolemia Shock Acidosis Hypothermia Hemodilution 4
5 Prevent death, do not use saline for gold fish 5
6 BEST Product for bleeding patients? Hypovolemia, acidosis/shock, NO RBC Microcirculation, Albumin, α 2 M, Haptoglobin, Coag factors. plasma instead of saline Deficit thrombin generation platelets/mp 6
7 What is 1:1:1? PRODUCT RBC ml Plasma ml PLT 10 9 AS ml US WB US RBC ? 15? 110 US PPP (FFP) 250? 15? US PRP US APH PLT (=6PRP) NLD WB (not avail.) NLD RBC (Bc v, LD, SAGM) NLD PLT (LD, plasma) NLD PLT (LD, PAS) NLD FFP (APH) NLD OMNIPLAS (S/D)
8 NLD Products; 3 units WB vs 3:3:1 ratio 8
9 PRO 1:1:1, PRO availability When suspect class III/IV hemorrhage ( 1.5L/5L) ASAP: Start with 2-4 RBC and 2 Plasma Then (if needed) followed by packages: 1 Platelet unit in plasma 3 Plasma 4 RBC 9 After hemodynamic stability achieved: Sample laboratory based transfusion
10 Trauma care and/or military scenarios Pre-hospital resuscitation? Logistic restraints? Massive blood loss? Mass Casualties? 10
11 NLD Military Blood Supply ISAF: Afghanistan, Tarin Kowt Transfusion: -80 C Frozen blood products are safe and effective in military casualty care. 11 PLOS ONE. 13 th Dec article?id= /journal.pone
12 272 trauma patients >0 RBC: 30% 6 RBC (MT);70% 1-5 RBC (n-mt) in 24hrs * * * * POST MTP ( 4:3:1 ratio ) 24hr blood use: MT 12:6:3 (median 10:5:2) RBC:Plasma:Plt Non-MT 3:1:0.5 (median 2:2:0) RBC:Plasma:Plt 12
13 Post MTP lower mortality * * * Despite increased injury and number of wounds, decreased mortality rates post MTP 13
14 Introduction of 4:3:1 MTP (Nov 2007) and 7d, 4 C stored thawed plasma (Apr 2009) units Thawed plasma at 4 C (max 7 days) Increased and earlier use of MTP Decreased mortality
15 PRO 1:1:1, PRO availability When suspect class III/IV hemorrhage ( 1.5L/5L) ASAP: Start with 2-4 RBC and 2 Plasma (Pre-Hosp?) Then (if needed) followed by packages: 1 Platelet unit in plasma 3 Plasma units 4 RBC units 15 After hemodynamic stability achieved: Sample laboratory based transfusion
16 Resuscitation..The sooner the better! Stop the bleeding Prevent/Treat ASAP: With compatible, safe blood products in a 1:1:1 ratio. 16
17 CON! Femke Noorman Military Blood Bank Leiden, The Netherlands 17
Experiences with frozen blood products in the Afghan theater (Aug 2006 Aug 2008)
Experiences with frozen blood products in the Afghan theater (Aug 2006 Aug 2008) CCM Lelkens, SBB(ASCP) Cdr (MC) (Royal Netherlands Navy) CO NLD Military Blood Bank 1 Outline Introduction ISAF / OEF facts
Pre-hospital Administration of Blood Products (PHBP) and Tranexamic acid (TXA): Is the Jury Still Out?
Pre-hospital Administration of Blood Products (PHBP) and Tranexamic acid (TXA): Is the Jury Still Out? Jessica K. Reynolds, MD Assistant Professor of Surgery University of Kentucky, Department of Trauma
Pediatric massive transfusion protocols
University of New Mexico UNM Digital Repository Emergency Medicine Research and Scholarship Emergency Medicine 2014 Pediatric massive transfusion protocols Ramsey Tate Follow this and additional works
Groupe d Intérêt en Hémostase Périopératoire
How do I treat massive bleeding? Red blood cell / plasma / platelet ratio and massive transfusion protocols Anne GODIER Service d Anesthésie-Réanimation Hopital Cochin Paris Groupe d Intérêt en Hémostase
Transfusion support during Mass Casualty Events
Transfusion support during Mass Casualty Events Dr Heidi Doughty Consultant in Transfusion Medicine NHS Blood and Transplant Birmingham Hon Senior Lecturer in Transfusion Medicine, Dept of Clinical Trauma,
Tactical Combat Casualty Care Guideline Change Fluid Resuscitation for Hemorrhagic Shock in TCCC
Tactical Combat Casualty Care Guideline Change 14-01 Fluid Resuscitation for Hemorrhagic Shock in TCCC 2 June 2014 Why a change was needed: The last update to the fluid resuscitation recommendations in
Remote Damage Control Resuscitation: An Overview for Medical Directors and Supervisors. THOR Collaboration
Remote Damage Control Resuscitation: An Overview for Medical Directors and Supervisors THOR Collaboration Agenda What is Remote Damage Control Resuscitation? Putting RDCR into Practice Control Hemorrhage
MASSIVE TRANSFUSION DR.K.HITESH KUMAR FINAL YEAR PG DEPT. OF TRANSFUSION MEDICINE
MASSIVE TRANSFUSION DR.K.HITESH KUMAR FINAL YEAR PG DEPT. OF TRANSFUSION MEDICINE CONTENTS Definition Indications Transfusion trigger Massive transfusion protocol Complications DEFINITION Massive transfusion:
Transfusion 2004: Current Practice Standards. Kay Elliott, MT (ASCP) SBB SWMC Transfusion Service
Transfusion 2004: Current Practice Standards Kay Elliott, MT (ASCP) SBB SWMC Transfusion Service Massive Transfusion Protocol (MTP) When should it be activated? Massive bleeding i.e. loss of one blood
1/16/2014 NONE WILL BE TALKING ABOUT NON FDA APPROVED DRUGS WILL LET YOU KNOW WHEN NOT ENDORSING ANY PARTICULAR PIECE OF EQUIPMENT
CUTTING EDGE TACTICAL MEDICINE SECRETS FROM THE BATTLEFIELD Brendan Anzalone, DO, Maj, USAF, MC Emergency Physician Special Tactics Medicine USAF Special Operations Surgical/Critical Care Evacuation Team
Massive transfusion: Recent advances, guidelines & strategies. Dr.A.Surekha Devi Head, Dept. of Transfusion Medicine Global Hospital Hyderabad
Massive transfusion: Recent advances, guidelines & strategies Dr.A.Surekha Devi Head, Dept. of Transfusion Medicine Global Hospital Hyderabad Massive Hemorrhage Introduction Hemorrhage is a major cause
Implementation and execution of civilian RDCR programs Minnesota RDCR
Implementation and execution of civilian RDCR programs Minnesota RDCR Donald H Jenkins, MD FACS Associate Professor of Surgery and Director of Trauma Division of Trauma, Critical Care and Emergency General
Armed Services Blood Program
Armed Services Blood Program Defense Health Board Concerns Regarding the Collection and Transfusion of Non-FDA Compliant Blood Products in Theater Information Brief Defense Health Board 17 August 2009
Management of the Trauma Patient. Elizabeth R Benjamin MD PhD Trauma and Surgical Critical Care Critical Care Symposium April 20, 2015
Management of the Trauma Patient Elizabeth R Benjamin MD PhD Trauma and Surgical Critical Care Critical Care Symposium April 20, 2015 Saturday Night 25 yo M s/p high speed MVC Hypotensive in the ED, altered
Strategies to Enhance Plasma Availability
Strategies to Enhance Plasma Availability Andrew Bernard, MD Professor of Surgery Medical Director, Acute Care Surgery and Trauma Chief, Section on Trauma and Acute Care Surgery Paul A. Kearney, MD Endowed
Coagulopathy: Measuring and Management. Nina A. Guzzetta, M.D. Children s Healthcare of Atlanta Emory University School of Medicine
Coagulopathy: Measuring and Management Nina A. Guzzetta, M.D. Children s Healthcare of Atlanta Emory University School of Medicine No Financial Disclosures Objectives Define coagulopathy of trauma Define
Kay Barrera MD. Surgery Grand Rounds June 19, 2014 SUNY Downstate
Kay Barrera MD Surgery Grand Rounds June 19, 2014 SUNY Downstate Kay Barrera MD Surgery Grand Rounds June 19, 2014 SUNY Downstate Outline Why are we talking about this SCORE expectations When do we use
The changing face of massive transfusion
The changing face of massive transfusion HAABB, Kansas City, 18 April 2018 John R. Hess, MD, MPH, FACP, FAAAS Professor of Laboratory Medicine Medical Director, Transfusion Service, Harborview MC U of
MASSIVE TRANSFUSION PROTOCOL
MASSIVE TRANSFUSION PROTOCOL IF YOU ANTICIPATE EMERGENT NEED FOR LARGE AMOUNTS OF BLOOD IN A SHORT PERIOD OF TIME Call Blood Bank: 6622121 Tell them you have a patient who needs a Massive Transfusion and
PEDIATRIC MASSIVE TRANSFUSION
PEDIATRIC MASSIVE TRANSFUSION CHELSEA RUNKLE RN, BSN, CCRN, SRNA CROZER-CHESTER MEDICAL CENTER/VILLANOVA UNIVERSITY NURSE ANESTHESIA PROGRAM LEADING CAUSE OF DEATH Trauma Motor vehicle accidents, nonaccidental
2/2/2011. Blood Components and Transfusions. Why Blood Transfusion?
Blood Components and Transfusions Describe blood components Identify nursing responsibilities r/t blood transfusion Discuss factors r/t blood transfusion including blood typing, Rh factor, and cross matching
Civilian versus Military Trauma Management
Western University From the SelectedWorks of Vivian C. McAlister November, 2010 Civilian versus Military Trauma Management Vivian C. McAlister Available at: https://works.bepress.com/vivianmcalister/151/
2 Liters. Goal: Basic Algorithm Volume Resuscitation in Trauma. Initial Fluids. Blood. Where do Blood Products Come From?
Goal: Basic Algorithm Volume Resuscitation in Trauma Sanjay Arora MD Associate Professor of Emergency Medicine Keck School of Medicine at USC Los Angeles County + USC Medical Center May 23, 2012 Initial
TXA. Things Change. Tranexamic Acid TXA. Resuscitation 2017 TXA In The ED March 31, MAST Trousers. High Flow IV Fluids.
Resuscitation 2017 In The ED March 31, 2017 Corey M. Slovis, M.D. Vanderbilt University Medical Center Metro Nashville Fire Department Nashville International Airport Nashville, TN SECURE THE ABC S MAST
Bleeding, Coagulopathy, and Thrombosis in the Injured Patient
Bleeding, Coagulopathy, and Thrombosis in the Injured Patient June 7, 2008 Kristan Staudenmayer, MD Trauma Fellow UCSF/SFGH Trauma deaths Sauaia A, et al. J Trauma. Feb 1995;38(2):185 Coagulopathy is Multi-factorial
ACCEPTABLE UNIVERSAL BLOOD PRODUCTS FOR RESUSCITATION?
ACCEPTABLE UNIVERSAL BLOOD PRODUCTS FOR RESUSCITATION? Paul M. Ness, M.D. Professor Pathology, Medicine, and Oncology The Johns Hopkins Medical Ins tu ons Bal more, Maryland, USA BLOOD BANK BUREAUCRATS
Kristan Staudenmayer, MD Stanford University, Stanford, CA
Kristan Staudenmayer, MD Stanford University, Stanford, CA Fluid resuscitation Variety of fluids How to administer What you do DOES matter WWII 1942 North Africa high mortality from hemorrhaghic shock
Source of platelet concentrates FACHBEREICH MEDIZIN
FACHBEREICH MEDIZIN Efficacy and safety of platelet concentrates from platelet apheresis donations or whole blood donations Gregor Bein Institute for Clinical Immunology and Transfusion Medicine Justus-Liebig-University
Epidemiology. Case. Pre-Hospital SI and Massive Transfusion
Epidemiology Preston Maxim, MD Assoc. Professor of Emergency Medicine San Francisco General Hospital ~180,000 deaths 2007 due to trauma 25% trauma patients require 1 unit of PRBC and only 25% of those
WELCOME. Evaluation Summary
WELCOME Evaluation Summary 489 delegates from 40 countries Delegate s specialty 239 respondents Delegate s professional activity 208 respondents Overall Evaluation This symposium was helpful for your clinical
TRANSFUSIONS FIRST, DO NO HARM
TRANSFUSIONS FIRST, DO NO HARM BECAUSE BLOOD CAN KILL 7 TRALI DEATHS SINCE 2002 WMC 5 women BECAUSE In OB you are transfusing 2 instead of 1 BECAUSE BLOOD IS A LIQUID TRANSPLANT RISKS versus BENEFITS versus
Transfusion Pitfalls. Objectives. Packed Red Blood Cells. TRICC trial (subgroups): Is transfusion always good? Components
Objectives Transfusion Pitfalls Gregory W. Hendey, MD, FACEP Professor and Chief UCSF Fresno, Emergency Medicine To list risks and benefits of various blood products To discuss controversy over liberal
Hemostatic Resuscitation
Hemostatic Resuscitation 30 th David Miller Trauma Symposium Bill Beck, MD Assistant Professor of Surgery Trauma, Emergency General Surgery, Critical Care Disclosures None Again. Mac user. Why I Like Trauma?
High Risk + Challenging Trauma Cases. Hawaii. Topics 1/27/2014. David Thompson, MD, MPH. Head injury in the anticoagulated patient.
High Risk + Challenging Trauma Cases David Thompson, MD, MPH Hawaii Topics Head injury in the anticoagulated patient Shock recognition Case 1: Head injury HPI: 57 yo male w/ PMH atrial fibrillation, on
Damage Control Resuscitation
Damage Control Resuscitation H M Cassimjee Critical Care Specialist Department of Critical Care & Level 1 Trauma Unit Inkosi Albert Luthuli Central Hospital Damage Control Resuscitation only for DAMAGED
MANAGEMENT OF COAGULOPATHY AFTER TRAUMA OR MAJOR SURGERY
MANAGEMENT OF COAGULOPATHY AFTER TRAUMA OR MAJOR SURGERY 19th ANNUAL CONTROVERSIES AND PROBLEMS IN SURGERY Thabo Mothabeng General Surgery: 1 Military Hospital HH Stone et al. Ann Surg. May 1983; 197(5):
Hemostatic Resuscitation in Trauma. Joanna Davidson, MD 6/6/2012
Hemostatic Resuscitation in Trauma { Joanna Davidson, MD 6/6/2012 Case of HM 28 yo M arrives CCH trauma bay 5/27/12 at 241 AM Restrained driver in low speed MVC after getting shot in the chest Arrived
Shock and Resuscitation: Part II. Patrick M Reilly MD FACS Professor of Surgery
Shock and Resuscitation: Part II Patrick M Reilly MD FACS Professor of Surgery Trauma Patient 1823 / 18 Police Dropoff Torso GSW Lower Midline / Right Buttock Shock This Monday Trauma Patient 1823 / 18
Heme (Bleeding and Coagulopathies) in the ICU
Heme (Bleeding and Coagulopathies) in the ICU General Topics To Discuss Transfusions DIC Thrombocytopenia Liver and renal disease related bleeding Lack of evidence in managing critical illness related
Massive Transfusion Initiation & Implication
Massive Transfusion Initiation & Implication Katayoun Fayaz MD Blood Bank Medical Director Northwell Health April 2017 Trauma Statistics/Facts Each year trauma accounts for 41 million emergency department
Adult Trauma Advances in Pediatrics. (sometimes they are little adults) FAST examination. Who is bleeding? How much and what kind of TXA volume?
Adult Trauma Advances in Pediatrics (sometimes they are little adults) Alisa McQueen MD, FAAP, FACEP Associate Professor of Pediatrics The University of Chicago Alisa McQueen MD, FAAP, FACEP Associate
Transfusion in major bleeding: new insights. Gert Poortmans
Transfusion in major bleeding: new insights Gert Poortmans Trauma Cardiac Surgery Major Surgery with ongoing blood loss Burn Surgery Lethal Triad Polytransfusion: definitions Coagulation Coagulopathy of
Managing Bleeding in the Patient on DOACs
Managing Bleeding in the Patient on DOACs Spring 2016 Jean M. Connors, MD Anticoagulation Management Services BWH/DFCI Hemostatic Antithrombotic Stewardship BWH Assistant Professor of Medicine, HMS Conflicts
FLUID MANAGEMENT AND BLOOD COMPONENT THERAPY
Manual: Section: Protocol #: Approval Date: Effective Date: Revision Due Date: 10/2019 LifeLine Patient Care Protocols Adult/Pediatrics AP1-011 10/2018 10/2018 FLUID MANAGEMENT AND BLOOD COMPONENT THERAPY
10/4/2018. Nothing to Disclose. Liz Robertson, MD FACS October 5, 2018 Steven R. Hall Trauma Symposium Big Cedar Lodge, MO
Nothing to Disclose Liz Robertson, MD FACS October 5, 2018 Steven R. Hall Trauma Symposium Big Cedar Lodge, MO History of IV Resuscitation Review of Data for Fluid Strategies Historical Examples of IV
Recombinant Activated Factor VII: Useful. Department of Surgery Grand Rounds 11/8/10 David Mauchley MD
Recombinant Activated Factor VII: Useful Department of Surgery Grand Rounds 11/8/10 David Mauchley MD Hemostasis and Coagulation Traditional cascade model Two convergent pathways Series of proteolytic
My Bloody Talk. Dr Ben Turner MBBS, FANZCA, FCICM The Royal Children s Hospital, Melbourne
My Bloody Talk Dr Ben Turner MBBS, FANZCA, FCICM The Royal Children s Hospital, Melbourne Disclosures No conflicts of interest Interest in conflict Blood transfusion Massive transfusion definitions Transfusion
Chest diseases Hospital Laboratory Hematology Practice guidelines
Chest diseases Hospital Laboratory Hematology Practice guidelines Title RBCs transfusion in Adults SOP Code Policy Owner Hematology Unit Section Hematology Prepared By Dr. Taher Ahmed Abdelhameed Issuing
Assessing thrombocytopenia in the intensive care unit: The past, present, and future
Assessing thrombocytopenia in the intensive care unit: The past, present, and future Ryan Zarychanski MD MSc FRCPC Sections of Critical Care and of Hematology, University of Manitoba Disclosures FINANCIAL
Thicker than Water. Alisa McQueen MD, FAAP, FACEP Associate Professor of Pediatrics The University of Chicago
Thicker than Water Alisa McQueen MD, FAAP, FACEP Associate Professor of Pediatrics The University of Chicago I have no relevant financial relationships to disclose. Who is bleeding? How much and what kind
Damage Control Resuscitation. VGH Trauma Rounds 2018 Harvey Hawes
Damage Control Resuscitation VGH Trauma Rounds 2018 Harvey Hawes Example Case 25yo F in motor vehicle collision at high speed Picked up at scene by Helicopter EMS unit Initial vital signs: HR 134 BP 88/42
Research Article. Trauma and Emergency Care ISSN: Introduction. Valeri CR*, Giorgio GR and CA Valeri
Trauma and Emergency Care Research Article ISSN: 2398-3345 The therapeutic effectiveness and safety of universal donor group O frozen RBC, group O frozen platelets, and group AB frozen plasma to treat
Surgical Resuscitation Management in Poly-Trauma Patients
Surgical Resuscitation Management in Poly-Trauma Patients Andrew Bernard, MD FACS Paul Kearney MD Chair of Trauma Surgery Associate Professor Medical Director of Trauma and Acute Care Surgery UK Healthcare
HYPOTHERMIA IN TRAUMA. Kevin Palmer EMT-P, DiMM
HYPOTHERMIA IN TRAUMA Kevin Palmer EMT-P, DiMM DISCLOSURE No Financial conflicts of interest Member of the Wilderness Medical Society Diploma in Mountain Medicine Fellowship in the Academy of Wilderness
Emergency Blood and Massive Transfusion: The Surgeon s Perspective. Transfusion Medicine Update September 16 17, 2009
Transfusion Medicine Update September 16 17, 2009 Mandip S. Atwal, D.O. FACOS Carl M. Pesta, D.O. FACOS Agenda History Hemorrhagic shock Transfusion is Bad Transfusion Prevention Transfusion The Red Chest
Transfusion Requirements and Management in Trauma RACHEL JACK
Transfusion Requirements and Management in Trauma RACHEL JACK Overview Haemostatic resuscitation Massive Transfusion Protocol Overview of NBA research guidelines Haemostatic resuscitation Permissive hypotension
UPDATE IN TRAUMA ANESTHESIA ARANA Spring Meeting May 5th, 2017 Joe Romero CRNA, MS, CPT USAR
UPDATE IN TRAUMA ANESTHESIA 2018 ARANA Spring Meeting May 5th, 2017 Joe Romero CRNA, MS, CPT USAR UPDATE IN TRAUMA ANESTHESIA 2018 - An overview of trauma demographics, mechanisms, and current literature
VanderbiltEM.com. Prehospital STEMIs. EMS Today 2018 Research That Should Be On Your Radar Screen 3/1/2018
EMS Today 2018 Research That Should Be On Your Radar Screen Corey M. Slovis, M.D. Vanderbilt University Medical Center Metro Nashville Fire Department Nashville International Airport Nashville, TN VanderbiltEM.com
Massive Transfusion. MPQC Spring Summit April 29, Roger Belizaire MD PhD
Massive Transfusion MPQC Spring Summit April 29, 2015 Roger Belizaire MD PhD Take home points 1. Blood is always available. Requests for massive transfusion or emergency release typically only require
WP-5:Use of Blood and Blood Products in Disasters , Israel
WP-5:Use of Blood and Blood Products in Disasters 24-25.11.08, Israel Identifying the Needs of Medical First Responder in Disasters (NMFRDisaster) Theme 10 Security; Call FP7-SEC-2007-1 Workshop Agenda
Mechanisms of Trauma Coagulopathy. Dr B M Schyma Changi General Hospital Singapore
Mechanisms of Trauma Coagulopathy Dr B M Schyma Changi General Hospital Singapore HAEMORRHAGE A continued cause of PREVENTABLE death. 24% of trauma patients are coagulopathic on arrival 1 56% of severe
DAMAGE CONTROL RESUSCITATION
DAMAGE CONTROL RESUSCITATION Chapter 4 Contributing Authors Jeremy G. Perkins, MD, FACP, LTC, MC, US Army Alec C. Beekley, MD, FACS, LTC, MC, US Army All figures and tables included in this chapter have
Define Shock, mostly as it relates to bleeding Options and evidence for tools of resuscitation Understand a little about coagulation and coagulopathy
Define Shock, mostly as it relates to bleeding Options and evidence for tools of resuscitation Understand a little about coagulation and coagulopathy 1:1:1 New advances Reduced perfusion of vital organs
3/16/15. Management of the Bleeding Trauma Patient: Concepts in Damage Control Resuscitation. Obligatory Traumatologist Slide
Management of the Bleeding Trauma Patient: Concepts in Damage Control Resuscitation Courtney Sommer, MD MPH Duke Trauma Symposium March 12, 2015 Obligatory Traumatologist Slide In 2010 trauma was leading
Clinical Overview of Coagulation Testing Issues
Clinical Overview of Coagulation Testing Issues Adam M. Vogel, MD Assistant Professor, Division of Pediatric Surgery Washington University in St. Louis School of Medicine September 19, 2014 Disclosure
TRAUMA RESUSCITATION. Dr. Carlos Palisi Dr. Nicholas Smith Liverpool Hospital
TRAUMA RESUSCITATION Dr. Carlos Palisi Dr. Nicholas Smith Liverpool Hospital First Principles.ATLS/EMST A- Airway and C-spine B- Breathing C- Circulation and Access D- Neurological deficit E- adequate
Massive Transfusion in Trauma
Page 1 Massive Transfusion in Trauma Robert S. Harris, M.D. Atlanta, Georgia Definitions and Demographics Hemorrhage is the second most common cause of death following injury and trauma, and is responsible
CrackCast Episode 7 Blood and Blood Components
CrackCast Episode 7 Blood and Blood Components Episode Overview: 1) Describe the 3 categories of blood antigens 2) Who is the universal donor and why? 3) Define massive transfusion 4) List 5 physiologic
How can ROTEM testing help you in trauma?
How can ROTEM testing help you in trauma? Complicated bleeding situations can appear intra and post operatively. They can be life-threatening and always require immediate action. A fast differential diagnosis
Resuscitation Update
Resuscitation Update? Dr. Edward Pyun Jr., M.D. FACS Trauma Medical Director/Surgical ICU Director OSF St. Anthony Medical Center Trauma Services Perryville Surgical Associates November 10, 2012 2009 Recommendations
Blood Management of the Cardiac Patient in the Postoperative Period
Blood Management of the Cardiac Patient in the Postoperative Period Al Stammers, MSA, CCP, Eric Tesdahl, PhD Andy Stasko MS, CCP, RRT, Linda Mongero, BS, CCP, Sam Weinstein, MD, MBA Goal To examine the
Financial Disclosure. Objectives 9/24/2018
Hemorrhage and Transfusion Adjuncts in the Setting of Damage Control Joseph Cuschieri, MD FACS Professor of Surgery, University of Washington Adjunct Professor of Orthopedics and Neurosurgery, University
I have no conflicts of interest to disclose. Major cause of mortality worldwide, more than 5 million deaths annually
I have no conflicts of interest to disclose Bethany Benish MD Asst. Professor Anesthesiology University of Colorado SOM Denver Health Medical Center 1 2 Review the challenges and complexities of Acute
Neue Wirkungsmechanismen von Transfusionsplasma
Neue Wirkungsmechanismen von Transfusionsplasma Lorenzo ALBERIO Médecin chef Hématologie générale et Hémostase Service et Laboratoire centrale d Hématologie CHUV, Lausanne Trauma patient Bleeding Thrombosis
Components of Blood. N26 Blood Administration 4/24/2012. Cabrillo College ADN/C. Madsen RN, MSN 1. Formed elements Cells. Plasma. What can we give?
Components of Blood Formed elements Cells Erythrocytes (RBCs) Leukocytes (WBCs) Thrombocytes (platelets) Plasma 90% water 10% solutes Proteins, clotting factors 1 What can we give? Whole blood Packed RBC
Hemostasis and thrombosis in patients with liver disease. Ton Lisman, Dept Surgery, UMC Groningen, The Netherlands
Hemostasis and thrombosis in patients with liver disease Ton Lisman, Dept Surgery, UMC Groningen, The Netherlands Importance of the liver in hemostasis Synthesis of Coagulation factors Fibrinolytic proteins
Reversal of Direct Oral Anticoagulants. Why are we now seeing so many patients on DOACs? Objectives. DOAC: Recurrent VTE. DOAC: Intracranial Bleeding
Reversal of Direct Oral Anticoagulants Cameron D Griffiths, MD, FRCPC Clinical Assistant Professor Division of Hematology UBC Objectives Review efficacy and safety data for Direct Oral Anticoagulants (DOACs)
Intraoperative haemorrhage and haemostasis. Dr. med. Christian Quadri Capoclinica Anestesia, ORL
Intraoperative haemorrhage and haemostasis Dr. med. Christian Quadri Capoclinica Anestesia, ORL Haemostasis is like love. Everybody talks about it, nobody understands it. JH Levy 2000 Intraoperative Haemorrhage
Blood Supply and Wastage
Blood Supply and Wastage Inga Willett Lab Matters, Oake Manor, 21 st June 2017 Blood supply UK supplied by 4 blood services: SNBTS NIBTS NHSBT WBS http://commons.wikimedia.org/wiki/file:uk_map_home_nations.png
Blood Components & Indications for Transfusion. Neda Kalhor
Blood Components & Indications for Transfusion Neda Kalhor Blood products Cellular Components: Red blood cells - Leukocyte-reduced RBCs - Washed RBCs - Irradiated RBCs Platelets - Random-donor platelets
Bassett Medical Center The Mary Imogene Bassett Hospital Clinical Laboratory Blood Bank Title: MTP 2016 Revision: 2.00 Created By: Admin, The Last
Bassett Medical Center The Mary Imogene Bassett Hospital Clinical Laboratory Blood Bank Title: MTP 2016 Revision: 2.00 Created By: Admin, The Last Approved Time: 7/22/2016 12:44:54 PM Massive Transfusion
GUIDANCE DOCUMENT FOR MASSIVE HEMORRHAGE MANAGEMENT IN ADULTS
GUIDANCE DOCUMENT FOR MASSIVE HEMORRHAGE MANAGEMENT IN ADULTS 1.0 Definitions & Acronyms 1.1 Massive Hemorrhage Event (MHE): Transfusion of a volume of blood components equivalent to a patient s estimated
Blood Reviews 23 (2009) Contents lists available at ScienceDirect. Blood Reviews. journal homepage:
Blood Reviews 23 (2009) 231 240 Contents lists available at ScienceDirect Blood Reviews journal homepage: www.elsevier.com/locate/blre REVIEW Resuscitation and transfusion principles for traumatic hemorrhagic
Pretransfusion Testing
Pretransfusion Testing Blood transfusion services The immunohematologic testing needed for By proper patient blood typing, component Dr. selection Reham and Talaat compatibility testing. Which Blood ensure
the bleeding won t stop? Liane Manz RN, BScN, CNCC(c) Royal Alexandra Hospital
What do you do when the bleeding won t stop? Teddie Tanguay RN, MN, NP, CNCC(c) Teddie Tanguay RN, MN, NP, CNCC(c) Liane Manz RN, BScN, CNCC(c) Royal Alexandra Hospital Outline Case study Normal coagulation
Blood Components Transfusion Criteria
Adults 1. Packed Cells: Dosage one unit of red blood cells will raise the Hbg by 1 gram; Hct by 3% in a 70Kg adult. Red Blood Cells should be transfused based on clinical need. In the absence of acute
Paediatric trauma resuscitation: an update
Eur J Trauma Emerg Surg (2016) 42:297 301 DOI 10.1007/s00068-015-0614-9 ORIGINAL ARTICLE Paediatric trauma resuscitation: an update T. H. Tosounidis 1,2 P. V. Giannoudis 1,2 Received: 18 November 2015
Prise en charge de la transfusion massive en chirurgie programmée et chez le polytraumatisé
Cours de sciences de base en anesthésiologie 2010 Prise en charge de la transfusion massive en chirurgie programmée et chez le polytraumatisé Jean-François Hardy MD, FRCPC Département d anesthésiologie
What is. InSpectra StO 2?
What is InSpectra StO 2? www.htibiomeasurement.com What is InSpectra StO 2? Hemoglobin O 2 saturation is measured in three areas: 1) Arterial (SaO 2, SpO 2 ) Assesses how well oxygen is loading onto hemoglobin
M.A.R.C.H. M.A.R.C.H. 10/11/2017. Hartford Consensus 2 April Comparison of Statistics for Battle Casualties,
Presented by: Envision/EM Care 15 th Annual Advanced Emergency and Acute Care Medicine Conference Stop the Bleed EAST COAST TACTICAL MEDICINE Dr. A. Scott Whyte Danny Devlin Emergency Physician Level II
Modulation of Vascular Stability in Traumatic Injury by Plasma
Modulation of Vascular Stability in Traumatic Injury by Plasma Shibani Pati MD. PhD. Blood Systems Research Institute and University of California San Francisco Remote Damage Control Resuscitation Meeting
Are Patients Hypoperfused in the ED? Rapid Perfusion Assessment in the Emergency Department
Are Patients Hypoperfused in the ED? Rapid Perfusion Assessment in the Emergency Department R. Benjamin Saldaña DO, FACEP Associate Medical Director Methodist Emergency Care Center, Houston TX Disclosure
RESUSCITATION IN TRAUMA. Important things I have learnt
RESUSCITATION IN TRAUMA Important things I have learnt Trauma resuscitation through the decades What was hot and now is not 1970s 1980s 1990s 2000s Now 1977 Fluids Summary Dogs subjected to arterial hemorrhage
BLOOD IN THE AIR: THE STARS EXPERIENCE Dr. Ryan Deedo MD DipAeroRT FRCPC Transport Physician STARS Medical Communications Lead (Calgary)
BLOOD IN THE AIR: THE STARS EXPERIENCE Dr. Ryan Deedo MD DipAeroRT FRCPC Transport Physician STARS Medical Communications Lead (Calgary) What s new at STARS? STARS bases and response areas Operations
5/30/2013. I have no conflicts of interest to disclose. Alicia Privette, MD Trauma & Critical Care Fellow. Trauma = #1 cause of death persons <40 yo 1
I have no conflicts of interest to disclose. Alicia Privette, MD Trauma & Critical Care Fellow Trauma = #1 cause of death persons
NIH Public Access Author Manuscript Blood Rev. Author manuscript; available in PMC 2011 August 22.
NIH Public Access Author Manuscript Published in final edited form as: Blood Rev. 2009 November ; 23(6): 231 240. doi:10.1016/j.blre.2009.07.003. Resuscitation and transfusion principles for traumatic
Battlefield Transfusions
Battlefield Transfusions Chapter 33 Battlefield Transfusions Introduction About 87% of battlefield deaths occur in the prehospital environment. Of these, 24% have been deemed to be potentially survivable,
Does a Controlled Fluid Resuscitation Strategy Decrease Mortality in Trauma Patients?
Does a Controlled Fluid Resuscitation Strategy Decrease Mortality in Trauma Patients? death Haemorrhage remains the biggest killer of major trauma patients Expected deaths will increase to 8 million/year
Management of Bleeding Pelvic Fractures
Management of Bleeding Pelvic Fractures Clay Cothren Burlew, MD FACS Professor of Surgery Program Director, SCC and TACS Fellowships Director, Surgical Intensive Care Unit Denver Health Medical Center/University
The principle of 1:1:1 blood product use in the resuscitation of trauma victims. K. D. Boffard
The principle of 1:1:1 blood product use in the resuscitation of trauma victims K. D. Boffard Milpark Hospital Department of Surgery University of the Witwatersrand Johannesburg, South Africa Annual Controversies