Supplementary appendix

Transcription

1 Supplementary appendix This appendix formed part of the original submission and has been peer reviewed. We post it as supplied by the authors. Supplement to: Jha V, Garcia-Garcia G, Iseki K, et al. Chronic kidney disease: global dimension and perspectives. Lancet 2013; published online May org/ /s (13)60687-x.

2 1 Table : Prevalence of indicators of chronic kidney disease around the world Reference Year of study Number of subjects Population Screening tools Prevalence of reduced GFR and proteinuria Australia Chadban ,247 Adults 7, 11 egfr<60 : 11.2% Proteinuria: 2.4% Hematuria: 4.6% Bangladesh Cravedi ,518 High-risk rural adults 1,10 egfr<60 : 8.6% Albuminuria: 45.4% Bolivia Cravedi ,436 Urban adults 1,11 egfr<60 : 3.2% Proteinuria: 4.5% Brazil Passos ,560 Urban adults 1742 > 60 y y 9 Serum creatinine (>1.3 mg/dl males, >1.2 females) 5.1% >60 y 0.5% y Cipullo ,717 Urban adults 8 Creatinine clearance < % China Zhang ,204 Urban and rural adults 5,10 Albuminuria 9.4% egfr<60 1.7% Zhang ,925 Urban and 5,10 Albuminuria 9.2% CKD stages Stage 3: 2.5% Stage 4: 0.4% Stage 5: 0.4% Stage 3: 7.4% Stage 4: 1.4% Stage 5: 0.1% Stage 1: 5.7% Stage 2: 3.4% Stage 3: 1.6% Stage 4/5: 0.1%

3 2 rural adults Hematuria 3.5% egfr<60 1.7% Zhang 7 2,353 Adults >40 y 5,10 Albuminuria 6.2% Hematuria 0.8% egfr<60 5.2% Chen ,311 Urban adults 3 egfr<60 :3.2% Albuminuria :6.6% Chen ,540 Urban and rural adults y Hematuria:3.8% 5,10 All CKD (agestandardized): 41.9% Liu ,214 Rural adults Albuminuria 7.1% Hematuria 4.6% egfr<60 2.6% Congo Sumaili Urban adults 1,7,11 egfr<60 MDRD: 8% C-G: 15.3% Proteinuria 18% India Varma ,850 Urban adults 1,2,10 Albuminuria 10% egfr<60 15% by MDRD 13.1% by CKD-EPI Stage 1: 1.9% Stage 2: 4.3% Stage 3: 5.2% Stage 2:39.4% Stage 3:2.4% Stage 4/5:0.14% MDRD and CG Stage 1: 2% and 1.4% Stage 2: 2.4% and 2.2% Stage 3: 7.8% and 15.0% Stage 4/5: 0.2% MDRD and CKD-EPI Stage 1: 6.6% and 6.7% Stage 2: 5.4% and 4.3% Stage 3: 3% and 2.1% Singh ,252 1,7 MDRD egfr<60 :4.2% CG egfr<60 :13.3% Proteinuria : 2.3% Iran Hosseinpanah ,063 Urban adults 1 egfr<60 Stage 3: 99.2%

4 % Italy Ravera ,525 Adult 1 egfr<60 hypertensive 3.3% Minutolo ,630 Adults 1 egfr<60 Crude 16.2% Age-adjusted 9.3% Japan Horio ,024 Adults 4,6 egfr< 60 By J-MDRD 7.7% By J-CKD-Epi 5.4% Stage 4: 0.7% Stage 5: 0.2% Stage 2: 5.8% Stage 3: 2.2% Stage 4/5: 1.1% Break-up of stages J-MDRD and J-CKDEpi Stage 1: 31.9% and 34.1% Stage 2: 60.1% and 60.5% Stage 3: 7.5% and 5.2% Stage 4/5: 0.2% each Imai ,594 Adults 4 All CKD 12.9% Stage 1:0.6% Stage 2:1.7% Stage 3:10.4% Stage 4/5:0.2% Iseki ,019 Adults 4 egfr< % Korea Kim ,356 Urban adults 1 All CKD :13.7% Stage 1:2.0% Stage 2: 6.7% Stage 3:4.8% Stage 4:0.2% Chang ,921 Urban adults 1,11 All CKD: 7.3% Proteinuria: 5.7% Mexico

5 4 Obrador ,539 High risk adults, 90% urban Amato 22 Not mentioned Mongolia Sharma High risk 1,10,11 egfr<60 6.2% proteinuria 16.8% 3,564 Urban adults 7 egfr<60 : 35.8% 1,10,11 egfr<60 8% Proteinuria 6.2% urban adults Nepal Cravedi ,811 Rural adults 1,11 egfr<60 : 19% Proteinuria: 3.5% Stage 1: 14% Stage 2: 9% Stage 3: 3.5% Stage 4/5: 1% Stage 3: 4.2% Stage 4: 0.2% Stage 5: 0.2% Stage 3: 7% Stage 4/5: 1% Stage 3: 18.6% Stage 4/5: 0.4% Norway Hallan ,939 Adults > 20 y 1 All CKD: 10.2% Stage 1: 2.7% Stage 2: 3.2% Stage 3: 4.2% Stage 4 :0.2% Spain Buitrago yr old urban 1,7 egfr<60 MDRD: 8.3% C-G: 11.6% Stage 1: 12.8% Stage 2 : 75.6% Stage 3: 11.6% Singapore Teo ,979 Multi ethnic adults 1,3 egfr<60 MDRD: 3.7% All subjects: Normal or stage 1: 45.7%, Stage 2: 50.6%, Stage 3: 3.3% Stage 4: 0.3% Stage 5: 0.08% Chinese, MDRD v C-MDRD

6 5 Stage1:15.2% and 29.3% Stage 2: 56.8% and 19.7% Stage 3: 3% and 0.8% Stage 4: 0.2% each Taiwan Wen ,293 1 Total CKD:11.9% Stage 1:1.0% Stage 2 : 3.8% Stage 3: 6.8% Stage 4 : 0.2% Stage 5:0.1% Hsu ,409 Adults 1 egfr<60 6.9% Kuo ,365 Adults ICD-9 All CKD: 9.8% Thailand Chittinandana ,612 Urban adults (Air Force forces) Perkovic ,146 Urban and rural adults > 35 y Ong-Ajyooth ,117 Urban and rural adults>15y codes 1,11 Proteinuria 1.9% egfr<60 7.4% C-G 3.1% MDRD 1,7 All CKD: 4.5% Urban: 4.8% Rural: 5.8% In >40 y old, stage % (CG) and 16.3# Progressive increase in prevalence from urban to rural and more to less developed (MDRD) 3 All CKD: 8.5% stage 3: 8.1% stage 4: 0.2% stage 5: 0.2% Kitiyakara ,152 Urban adults 1,2,3,6, egfr<60 CKD-EPI: 12.2% MDRD: 20.2% Stage 1: 29.2% Stage 2: 65.5% Stage 3: 5.4% Stage 4/5: 0.1%

7 6 J-CKD-Epi: 37.9% C-MDRD: 5.5% T-GFR: 5.4% USA Coresh ,233 Adults 1 Stage 1: 1.8% Stage 2: 3.2% Stage 3:7.7% Stage 4:0.35% 1MDRD egfr, 2 CKD-EPI egfr, 3 Chinese and 4 Japanese modifications of MDRD equation, 5 Chinese and 6 Japanese modifications of CKD-EPI equation, 7 Cockroft and Gault equation, 8 24-h urinary creatinine clearance, 9 Serum creatinine, 10 microalbuminuria, 11dipstick proteinuria, 12 Serum creatinine, 13 Thai GFR equation

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