WHO International Biological Reference Preparations Held and distributed by the WHO International Laboratories for Biological Standards
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1 WHO International Biological Preparations Activin A, human, recombinant. Lyophilized. 5 units / Reagent, 1998 No th NIBSC 91/ Arginine vasopressin. Lyophilized. 8.2 IU / Standard, 1978 No. 638, 30th Hormone NIBSC 77/ Atrial natriuretic factor, human. Lyophilized. 2.5 IU / Standard, 1987 No. 771, 38th Peptide NIBSC 85/ Calcitonin, eel. Lyophilized. 88 IU / Standard, 1989 No. 800, 40th Hormone NIBSC 88/ Calcitonin, human. Lyophilized IU / Standard, 1991 No. 822, 42nd Hormone NIBSC 89/ Calcitonin, salmon. Lyophilized. 138 IU / 3rd-International Standard, 1999 No. 904, 50th Hormone NIBSC 98/ Chorionic gonadotrophin, alpha subunit, human, for immunoassay. Lyophilized. 70 IU / Preparation, 1974 No. 565, 26th Glycoprotein NIBSC 75/ Chorionic gonadotrophin, beta subunit, human, for immunoassay. Lyophilized. 70 IU / Preparation, 1974 No. 565, 26th Glycoprotein NIBSC 75/ Chorionic gonadotrophin, human. Lyophilized. 650 IU / 4th-International Standard, 1999 No. 904, 50th Glycoprotein NIBSC 75/ Corticotrophin (ACTH), porcine. Lyophilized. 5 IU / 3rd-International Standard, 1962 No. 259, 15th NIBSC 59/ Page 1 of 8
2 WHO International Biological Preparations Elcatonin (Calcitonin analogue). Lyophilized. 15 IU / No. 760, 37th Endocrinologic al products NIBSC 84/ Erythropoietin, human, urinary. Lyophilized. 10 IU / Preparation, 1970 No. 463, 23rd Urinary NIBSC 67/ Erythropoietin, rdna-derived. Lyophilized. 120 IU / Standard, 2003 No. 926, 53rd NIBSC 88/ Follicle stimulating, human, recombinant, for bioassay. Lyophilized. 138 IU / Standard, 1995 No. 872, 46th NIBSC 92/ Follicle stimulating, human, pituitary. Lyophilized. 80 IU / No. 760, 37th NIBSC 83/ Follicle stimulating, human, recombinant for immunoassay. Lyophilized. 60 IU / Standard, 1997 No. 889, 48th NIBSC 92/ Follicle stimulating, human, urinary (Urofollitropin), for bioassay. Lyophilized. 121 IU / Standard, 1995 No. 872, 46th Urinary NIBSC 92/ Follicle-stimulating and luteinising human, urinary for bioassay. Lyophilized. FSH 72 IU / LH 70 IU / 4th-International Standard, 2000 No. 910, 51st Urinary NIBSC 98/ Glucagon, porcine. Lyophilized IU / Standard, 1973 No. 530, 25th Gastrointestinal NIBSC 69/ Page 2 of 8
3 WHO International Biological Preparations Gonadotrophin, equine serum. Lyophilized. 1,600 IU / Standard, 1966 No. 361, 19th Horse serum NIBSC 62/ Human Chorionic Gonadotrophin for immunoassay of intact hcg. Lyophilized nmol / Hormone.Intact hcg: purified to remove nicked forms, and free subunits NIBSC 99/ alpha subunit hcg (hcg-alpha). Lyophilized nmol / Hormone. Purified alpha subunit of hcg NIBSC 99/ beta core fragment hcg (hcg-beta-cf). Lyophilized nmol / ampoule Hormone. hcg beta core fragment: residues beta 6-40 disulphide bonded to beta NIBSC 99/ hcg beta subunit (hcg-beta). Lyophilized nmol/ampoule Hormone. Beta subunit of hcg, purified to remove intact dimeric hcg, alpha subunit and nicked beta subunit NIBSC 99/ Page 3 of 8
4 WHO International Biological Preparations nicked hcg (hcg-n). Lyophilized nmol/ampoule Hormone. Nicked hcg: partially degraded hcg, missing bonds in the beta region NIBSC 99/ nicked hcg beta subunit (hcg-beta-n). Lyophilized nmol/ampoule Hormone. Nicked hcg beta subunit: partially degraded beta subunit, missing bonds in the beta region NIBSC 99/ Human growth, pituitary. Lyophilized. 4.4 IU / Standard, 1982 No. 687, 33rd NIBSC 80/ Inhibin A, human, recombinant. Lyophilized. 150,000 IU / Standard, 1994 No. 858, 45th ; No. 910, 51st NIBSC 91/ Inhibin B. Lyophilized. Immunoassay calibration 12 ng / Bioactivity: 12 units / Reagent, 2000 No. 910, 51st Immunoaffinity purified human inhibin NIBSC 96/ Page 4 of 8
5 WHO International Biological Preparations Inhibin, porcine. Lyophilized. 2,000 IU / Standard, 1990 No. 814, 41st Purified porcine NIBSC 86/ Insulin C-, human. Lyophilized. 10 µg / Reagent, 1986 No. 760, 37th Synthetic C- NIBSC 84/ Insulin, bovine. Hydrated crystals IU / mg. Approximately 50 mg / Insulin, human. Hydrated crystals. 26 IU / mg. Approximately 50 mg / Insulin, human, for immunoassay. Lyophilized. 3 IU / Insulin, porcine. Hydrated crystals. 26 IU / mg. Approximately 50 mg / Preparation, 1974 No. 760, 37th Insulin crystals NIBSC 83/ No. 760, 37th Insulin crystals NIBSC 83/ No. 565, 26th Human insulin NIBSC 66/ No. 760, 37th Insulin crystals NIBSC 83/ Insulin-like growth factor I for immunoassay. Lyophilized. 3.1 µg / Reagent, 2000 No. 910, 51st NIBSC 87/ Leptin, human. Lyophilized. 4,000 IU / Standard, 1999 No. 904, 50th / E.Coli NIBSC 97/ Leptin, mouse. Lyophilized. 4,000 IU / Standard, 1999 No. 904, 50th / E.Coli NIBSC 97/ Luteinizing, bovine, for immunoassay. Lyophilized IU / Standard, 1985 No. 745, 36th NIBSC 98/ Page 5 of 8
6 WHO International Biological Preparations Luteinizing, human, pituitary. Lyophilized. 35 IU / Standard, 1988 No. 786, 39th NIBSC 80/ Luteinizing, human, pituitary, alpha subunit. Lyophilized. 10 IU / Standard, 1984 No. 725, 35th NIBSC 78/ Luteinizing, human, pituitary, beta subunit. Lyophilized. 10 IU / Standard, 1984 No. 725, 35th NIBSC 78/ Lysine vasopressin. Lyophilized. 7.7 IU / Standard, 1978 No. 638, 30th Synthetic NIBSC 77/ Oxytocin. Lyophilized IU / 4th-International Standard, 1978 No. 638, 30th Synthetic oxytocin NIBSC 76/ Parathyroid, bovine. Lyophilized. 39 IU / Standard, 1985 No. 745, 36th Parathyroid NIBSC 82/ Parathyroid, human, for immunoassay. Lyophilized. 0.1 IU / Preparation, 1981 No.673, 32nd Parathyroid NIBSC 79/ Placental lactogen, human, for immunoassay. Lyophilized IU / Preparation, 1977 No. 626, 29th Purified placental protein NIBSC 73/ Proinsulin, bovine, for immunoassay. Lyophilized. 25 µg / No. 760, 37th Pancreatic enzyme NIBSC 84/ Page 6 of 8
7 WHO International Biological Preparations Proinsulin, human. Lyophilized. 6 µg / Reagent, 1986 No. 760, 37th proinsulin NIBSC 84/ Proinsulin, porcine, for immunoassay. Lyophilized. 20 µg / No. 760, 37th Pancreatic enzyme NIBSC 84/ Prolactin, human. Lyophilized IU / 3rd-International Standard, 1988 No. 786, 39th NIBSC 84/ Prolactin, recombinant human, for immunoassay. Lyophilized. Nominal content for immunization calibration: 24.5 µg / ampoule; for bioassay calibration: 1,400 mu / rdna derived prolactin NIBSC 97/ Prolactin, recombinant human, glycosylated form, for immunoassay. Lyophilized. Nominal content for immunization calibration: 5.5 µg / ampoule; for bioassay calibration: 88 mu / NIBSC 98/ Prolactin, recombinant human, non-glycosylated form, for immunoassay. Lyophilized µg / ampoule; for bioassay: 670 mu / rdna derived prolactin, nonglycosylated form NIBSC 98/ Renin, human. Lyophilized. 0.1 IU / Preparation, 1974 No. 565, 26th Kidney extract derived NIBSC 68/ Sex binding globulin (SHBG). Lyophilized. 107 IU / Standard, 1998 No. 897, 49th Human serum NIBSC 95/560 98/1884 Page 7 of 8
8 WHO International Biological Preparations Somatropin (rdna-derived human growth ). Lyophilized mg protein / Standard, 2000 No. 910, 51st / E.Coli NIBSC 98/ Tetracosactide. Lyophilized. 490 IU / Preparation, 1981 No. 673, 32nd Synthetic NIBSC 80/ Thyroid stimulating, human, for immunoassay. Lyophilized x -3 log 10 IU / 3rd-International Standard, 2003 In press NIBSC 81/ Thyroid-stimulating, human, recombinant. Lyophilized units / Reagent, 1996 No. 878, 47th, [Chinese Hamster Ovary cells (CHO)] NIBSC 94/ Thyroxine-binding globulin. Lyophilized. 30 IU / Standard, 1991 No. 822, 42nd Human serum derived NIBSC 88/ Page 8 of 8
PREPARATION STANDARD MATERIAL HELD AT CODE WHO/BS DOCUMENT. Native hormone purified from urine
WHO International Biological Reference Preparations Held and Distributed by the WHO International Laboratories for Biological Standards ENDOCRINOLOGICAL SUBSTANCES Activin A, human, recombinant, Lyophilized,
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WHO International Biological Reference Preparations Held and Distributed by the WHO International Laboratories for Biological Standards
WHO International Biological Reference Preparations Held and Distributed by the WHO International Laboratories for Biological Standards PREPARATION Activin A, human, recombinant, Lyophilized., 5 units
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WHO International Biological Reference Preparations Held and distributed by the WHO International Laboratories for Biological Standards
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