Immunology/ Transplantation. Epidemiology/ Genetics

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1 FRIDAY, JUNE 22, 2018 Registration Hours: 9:00 a.m. 6:30 p.m. Shop Store Hours: 9:00 a.m. 6:30 p.m. 11:30 a.m. 12:30 p.m. Mini- Measuring Neuropathy Is Corneal Confocal Microscopy Ready for Prime Time? Mini- Biofilm Real Wound Problem or Just a Buzzword? Mini- Tech and Teens Mini- Myth or Science? Current Fads and Evidence in Diet and Nutrition Mini- Innovations in Pregnancy Care Mini- New-Onset Type 2 in the Youngest and the Oldest Mini- The Emerging Role of Neoepitopes in the Dialogue between T Cells and Beta Cells Mini- The Banting Exchange New Concepts in the Pathogenesis of and Metabolic Disease Mini- New Regulators of Beta-Cell Identity 12:45 p.m. 1:45 p.m. Mini- Surveillance of Kidney Disease and Comorbidities among People with What We Can Learn from the CDC s Chronic Kidney Disease Surveillance System Mini- Understanding Hybrid Closed-Loop Pump Mini- Youth-Onset Type 2 and Exercise Outcomes and Challenges Mini- Improving Patient-Provider Communication in the Management of in Culturally Diverse Populations Mini- Better Ways to Build Population Health Management Mini- Challenging Times for Youth with Type 1 How Do We Approach Them? Mini- The Future of Islet Transplant Towards a Renewable Source of Beta Cells Mini- Near, Far, Wherever You Are Obesity-Related Defects in Insulin Signaling Mini- Of Mice, Mongrels, and Men Commonalities and Differences in Metabolic Research

2 FRIDAY, JUNE 22, 2018 (CONTINUED) Registration Hours: 9:00 a.m. 6:30 p.m. Shop Store Hours: 9:00 a.m. 6:30 p.m. 2:00 p.m. 4:00 p.m. Antiplatelet and Antithrombotic Therapies in Decreasing Risk for Type 2 with Foods Artificial Pancreas and Decision Support Approaches Real-World Evidence in Mental Health Disorders and Distress among Adults with Endocrine, Paracrine Signaling Affecting Adipocyte Function The Exosome Superhighway in Energy and Metabolic Homeostasis Transformational Technologies in Islet Biology From Omics to Imaging 4:15 p.m. 6:15 p.m. The Many Faces of Hypoglycemia Impact on Patient Health and Well-Being Data, Data, Everywhere and Not a Pattern to Be Found Current Issues (4:15 p.m. 5:10 p.m.) Cardiovascular Outcomes Trials (CVOTs) in Shall We Continue or Change Course?, Adipose Tissue, Obesity, and Type 2 Novel Approaches to Advancing Islet Basic Science Adipose Differentiation and Function DiRECT Links between Hepatic Metabolism, Glucagon Action, and Glucose Turnover Balancing Proliferation and Maturation in the Islet (With ADA Presidents Select Abstract) Dynamic Approaches to Improve Glycemic Control and Primary Care Glucose Monitoring Advances, Pitfalls, and Clinical Relevance Current Issues (5:20 p.m. 6:15 p.m.) Should Metformin Remain the First- Line Therapy for Type 2? 6:30 p.m. 8:30 p.m. Networking Reception Orange County Convention Center (Level 4 Foyer)

3 SATURDAY, JUNE 23, 2018 Registration Hours: 7:00 a.m. 6:30 p.m. Shop Store Hours: 7:30 a.m. 6:15 p.m. Exhibit Hall Hours: 10:00 a.m. 4:00 p.m. Poster Hall Hours: 10:00 a.m. 6:00 p.m. 8:00 a.m. 10:00 a.m. Is It Osteomyelitis or Not? Diagnostic and Treatment Dilemmas in Bone Infection What s New in Diabetic Neuropathy? Equal Parts Clinical and Basic Science ADA Education Recognition Program Implementing Technology-Enabled Care Management Processes for Population Health Conception, Build, Implementation, Outcomes, and Sustainability Have You Seen Your Mother, Baby? Placenta- Derived Biomarkers of Adverse Pregnancy Outcomes in Gestational Mellitus and Type 2 in Youth HIV and The Double Whammy Overcoming Challenges in Islet Engineering and Protecting Beta Cells Hepatokines and Metabolic Regulation A Liver- Centric Point of View Turning Up the Heat New Regulators of Thermogenesis in Mice and Humans Targeting Beta-Cell Apoptosis and Death Effects of Exercise on Metabolic Health in Type 1 and Type 2 (With ADA Presidents Select Abstract) ADA Care Using Continuous Glucose Monitoring and Smart Devices to Control Glucose when It Matters Most Emerging Targets for Treatment 10:15 a.m. 11:15 a.m. President, Health Care & Education Address and Outstanding Educator in Award Lecture 11:30 a.m. 12:30 p.m. The Best and Worst Practices in Managing the Diabetic Foot Update on Nonnutritive Sweeteners and Cardiometabolic Health Mini- Quantifying Genomics, Electronic Health Records, and Automated Control Reframing Exercise The Surprising Science behind Motivating Patients to Be More Physically Active 11:30 a.m. 12:30 p.m. General Poster Session Hall WA4-WB2 (Poster Hall) 11:30 a.m. 1:30 p.m. Moderated Poster Discussions Hall WA4-WB2 (Poster Hall)/Hall WA1-WA3 (Exhibit Hall)

4 Registration Hours: 7:00 a.m. 6:30 p.m. Shop Store Hours: 7:30 a.m. 6:15 p.m. DAY-AT-A-GLANCE SCHEDULE SATURDAY, JUNE 23, 2018 (CONTINUED) Exhibit Hall Hours: 10:00 a.m. 4:00 p.m. Poster Hall Hours: 10:00 a.m. 6:00 p.m. 1:45 p.m. 3:45 p.m. The Resurgence of Triglyceride-Rich Lipoproteins as an Important Target in the Treatment of Dyslipidemia What Is New in Diabetic Kidney Disease? (With Stateof-the-Art Lecture and ADA Presidents Select Abstract) Making a Difference in Five Minutes Interventions in for Anyone (With Richard R. Rubin Award Lecture) Role of Exercise in Regulating Mitochondrial Dynamics National Implementation and Dissemination of Research to Improve Patient Safety and Reduce Hypoglycemia The Do-It-Yourself (DIY) Revolution Exploring the Next Frontier in Pharmacology Lessons Learned from the Environmental Determinants of in the Young (TEDDY) Study Insights into Early Autoimmune Type 1 Case Studies Monogenic Testing Is Ready for Prime Time Integrating into Your Practice New Insights into the Immunology of Human Type 1 The Intestine in the Regulation of Metabolism, Immunity, and Insulin Sensitivity Steering the Right Course for Management Clinical Perspectives Beta-Cell Dedifferentiation True or False? 4:00 p.m. 6:00 p.m. Hypoglycemia Reducing the Risk Research Advances in the Diabetic Foot (With Roger Pecoraro Award Lecture) Nutrition and the Gut Microbiome Online and Mobile Support Wading through the Noise Joint ADA/ISPAD 25 Years after the Announcement of the DCCT Results What Is the Status of Type 1 in Youth, and How Can We Do Better? Joint ADA/Chinese Society Glucose and Lipid Metabolism Novel Mechanisms and Targets It s Not Too Late, Baby Outcomes in Gestational Mellitus (With Norbert Freinkel Award Lecture) Updates from Type 2 Trials The Impact of Interventions and Behaviors on Outcomes Clinical Progress in Islet Clinical Science Mitochondrial Dynamics, Metabolism, and Insulin Action G is for GLP, GIP, and Glucagon A NOD to the Gut Liver Axis Muscling In on the Heart of Metabolism and Insulin Sensitivity Neurotransmitters in the Islet

5 Registration Hours: 7:30 a.m. 5:00 p.m. Shop Store Hours: 7:30 a.m. 6:45 p.m. DAY-AT-A-GLANCE SCHEDULE SUNDAY, JUNE 24, 2018 WEAR RED DAY Exhibit Hall Hours: 10:00 a.m. 4:00 p.m. Poster Hall Hours: 7:30 a.m. 6:30 p.m. 8:00 a.m. 10:00 a.m. The Where and Why of Diabetic Neuropathy Blood Flow to the Toe Prediction and Prevention of Cardiovascular Disease Building a Case for Getting Reimbursement or Payment for Behavioral Health in NDEP Prevention, Care, and Education in the Digital Age Unrecognized (Occult) Metabolic Conditions in Women with Gestational Mellitus that Predict Metabolic Later in Life Prioritizing Injectable Therapies in Type 2 and Risk Factors Challenges and Hope in Finding a Cure for Type 1 Molecular Mechanisms of Insulin Action and Resistance in Peripheral Tissues Precision Medicine in ADA Emerging Areas of Islet Biology Novel Signaling Pathways in the Islet Enhancing the Use of Prevention and Cardiovascular Risk Factor Control 10:15 a.m. 11:45 a.m. President, Medicine & Science Address and Banting Medal for Scientific Achievement Room: Hall WB4 12:00 p.m. 1:00 p.m. Mini- The Importance of the Functional Characteristics of HDL Mini- Update on Diabetic Retinopathy Clinical Trials Moving Past the Randomized Controlled Trial Understanding the Need for Implementation Science in Care The Future of Education Live Educator and Virtual Coach Partners in Care Beyond HbA1c in Pediatric Is It Time to Look at Other Outcomes? Clinical Centers and Programs Session I Mini- Update on the of Type 1 and Type 2 12:00 p.m. 1:00 p.m. General Poster Session/Moderated Poster Discussions Hall WA4-WB2 (Poster Hall)/Hall WA1-WA3 (Exhibit Hall) 1:00 p.m. 2:00 p.m. Session Break (Take this opportunity to visit the Exhibit and Poster Halls)

6 Registration Hours: 7:30 a.m. 5:00 p.m. Shop Store Hours: 7:30 a.m. 6:45 p.m. DAY-AT-A-GLANCE SCHEDULE SUNDAY, JUNE 24, 2018 WEAR RED DAY (CONTINUED) Exhibit Hall Hours: 10:00 a.m. 4:00 p.m. Poster Hall Hours: 7:30 a.m. 6:30 p.m. 2:15 p.m. 4:15 p.m. Joint ADA/ASN Management of Patients with Progressing Diabetic Kidney Disease (DKD) New Insights into the Mechanisms of Defective Hypoglycemia Counterregulation in (With ADA Presidents Select Abstract) Innovative Strategies to Improve the Inpatient Experience Aerobic Exercise in the Prevention of Cognitive Decline in The National Prevention Program From Research to Practice to National Policy Joint ADA/JDRF Current Management of Type 1 in Youth What Are the Options? Addressing Unique Challenges in Management (2:15 p.m. 3:00 p.m.) Kelly West Award for Outstanding Achievement in Epidemiology Lecture Joint ADA/ UK Cell Therapy for International Progress Fuel Driving Function Lipidic Roles in Different Tissues Ordering from the Weight- Loss Menu in the Era of Precision Medicine for Obesity More to Mitochondria in the Beta Cell Clinical Trials in Type 1 4:30 p.m. 6:30 p.m. Neuro- and Glial-Vascular Effects in the Pathogenesis of Diabetic Retinopathy The Veterans Affairs Trial (VADT) at 15 Years Low-Carbohydrate Diets Potential Benefits, Risks, and Costs High Risk Behavioral and Psychosocial Issues in Prevention What Are We Preventing? Joint ADA/AACC Refining Measurement of A1C Do We Know What It Means? Basic and Translational Mechanisms in Gestational Mellitus Academia-Industry Collaborations Key Considerations Beyond Single Nucleotide Polymorphisms Building on Knowledge of the Genetic Architecture of Novel Pathogenetic Pathways in Type 1 What Can We Learn from Cancer Immunotherapy? New Angles in Adipose Biology Joint ADA/EASD Central Control of Glucose Homeostasis Alpha Cells New Sources of Beta Cells? From Progression to Management in Type 1 What Is New? (With ADA Presidents Select Abstract)

7 MONDAY, JUNE 25, 2018 Registration Hours: 7:30 a.m. 4:00 p.m. Shop Store Hours: 7:30 a.m. 6:45 p.m. Exhibit Hall Hours: 10:00 a.m. 2:00 p.m. Poster Hall Hours: 7:30 a.m. 2:00 p.m. 8:00 a.m. 10:00 a.m. Role of the Kidney in Heart Health New Insights into the Pathogenesis of Diabetic Retinopathy Intervening in the Lived Experiences and Social Context of Those with Self-Management Education and Support Embracing Data and Digital Dialogue Advances Who Do You Think You Are? Heterogeneity of Obesity and Gestational Mellitus Type 2 in Youth Update on the Current State of Knowledge on Effectiveness of Telemedicine in Underserved Communities Genetic and Ethnic Heterogeneity and the Road to Precision Medicine in (With ADA Presidents Select Abstract) Clinical Trials for Type 1 Current, Emerging, and Novel Adipose Browning and Energy Expenditure (With State-of-the-Art Lecture) Recognition of Depression,, and Dementia Resetting Clinical Priorities Novel Mediators and Mechanisms of Obesity Pathogenesis in Animals Metabolism and the Beta Cell SGLT2 Inhibitors From Mechanisms to Clinical Trials (With ADA Presidents Select Abstract) 10:10 a.m. 11:45 a.m. 12:00 p.m. 1:00 p.m. 12:00 p.m. 1:00 p.m. 1:00 p.m. 2:00 p.m. Mini- Special Topics in Hypoglycemia Mini- Overcoming Gender Gaps in Science National Scientific & Health Care Achievement Awards Presentation and Outstanding Scientific Achievement Award Lecture Room: Hall WB4 The Lancet Commission on Societal Solutions to Combat Should All Pregnant Women with Type 1 Use Continuous Glucose Monitoring from Planning Pregnancy until after Breastfeeding? Clinical Centers and Programs Session II Group Session Defining a Healthy Diet Do Fats or Carbohydrates Matter More? Group Session Immunopathogenesis of Type 1 Is It Autoimmunity? General Poster Session/Moderated Poster Discussions Hall WA4-WB2 (Poster Hall)/Hall WA1-WA3 (Exhibit Hall) Session Break (Take this opportunity to visit the Exhibit and Poster Halls)

8 Registration Hours: 7:30 a.m. 4:00 p.m. Shop Store Hours: 7:30 a.m. 6:45 p.m. DAY-AT-A-GLANCE SCHEDULE MONDAY, JUNE 25, 2018 (CONTINUED) Exhibit Hall Hours: 10:00 a.m. 2:00 p.m. Poster Hall Hours: 7:30 a.m. 2:00 p.m. 2:15 p.m. 4:15 p.m. Evolving Mechanisms in Cardiovascular (With Edwin Bierman Award Lecture) Easing Disease Management Burden for Older Adults Nutrition 2018 New Data, New Perspectives Cost-Related Nonadherence to Care The Restoring Insulin Secretion (RISE) Study in Youth and Adults Baseline Data and Results of the Pediatric Medication Study Race and Societal Influences on (With Vivian Fonseca and Nagendran Family Research Award Presentation) Translational Immunology in Type 1 A Look at the Future Adipose Signaling and the Central Nervous System in the Control of Obesity Diversity Affairs Impact of Genetic Variability and Sex on Integrative Metabolism and Disease Risk Regulation of Islet Function in Health and Disease Preventing and Treating Hypoglycemia 4:30 p.m. 6:30 p.m. Current Issues Albuminuria Two Debates Clinical Strategies for Prevention and Management of Hypoglycemia New Insights into Lipid and Lipoprotein Alterations in Patients with and Psychosocial Risk Factors in the Hispanic Community Health Study/Study of Latinos Using mhealth for Obesity Treatment and Weight Management Insulin Therapy To the Future and Back Adiposity, Insulin Resistance, and Type 2 Mellitus What Is New in Risk Factors and Biomarkers? Innovations in Insulin Formulation and Delivery Mechanistic Insights from Rare Conditions and Opportunities for Novel Clinical Updates in Beta-Cell Replacement Therapy Novel Aspects of Metabolic Regulation (With ADA Presidents Select Abstract) Human Obesity Pathogenesis From Brain to Peripheral Organs Alphabet Soup GABA, FGF, ERα Recipe for Central Nervous System Control of Metabolic Homeostasis and Remission (With State-of-the-Art Lecture) The Islet in Type 1 What s New?

9 TUESDAY, JUNE 26, 2018 Registration Hours: 7:30 a.m. 10:30 a.m. Shop Store Hours: 7:30 a.m. 12:30 p.m. 8:00 a.m. 10:00 a.m. Cardiorenal Effects of Glucose-Lowering Therapies Multigenerational Effects of Exercise Management of in a Surgical Patient Obesity in Type 1 An Evolving Challenge in Rural America Aging and Insulin Sensitivity Nutrient Sensing and Signaling in the Regulation of Metabolic Homeostasis G-Protein-Coupled Receptors Structural Insights to Therapeutic Options Management of Hyperglycemia in Type 2 Draft ADA/EASD Consensus Report :15 a.m. 12:15 p.m. SGLT Inhibition for Type 1 Mellitus Management How Far Have We Gone?

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