Microlife - A partner for people. For life.

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1 Product Catalogue 2016 / 2017

2 Microlife A partner for people. For life. Microlife is one of the world leaders in development and manufacturing of medical diagnostic equipment for home monitoring and institutional use. Blood pressure monitors, digital thermometers, asthma monitors and flexible heating are Microlife s core business. As the pioneer of the mercuryfree digital thermometer, Microlife products are free of environmentally hazardous substances. We strive for high quality, reliability and accuracy. We develop techno logy for the benefit of your health and set the quality standard just as high as for professional applications. Our medical devices are clinically validated and guarantee the highest level of safety. They are robust and easy to use. Whether it is blood pressure, fever, asthma, weight management or flexible heating, Microlife s technologies provide you with accurate and reliable solutions for children and adults. Our vision is to empower people through our products and services to be able to manage and promote their own health. Microlife AG, Switzerland Swiss Design Logo This Swiss Design logo serves as a specific identifier of the Microlife Master Brand, that supports our commitment and dedication towards the high quality of design that we put into the making of all our products and solutions. NICE RECOMMENDED BY National Health Service National Institute for Health and Care Excellence (NICE) Recommendation Microlife WatchBP Home A is the only officially recommended blood pressure monitor for use during routine blood pressure measurement for all GP s and primary care professionals in the United Kingdom (NHS), as it simultaneously can detect atrial fibrillation during blood pressure measurement. Red Dot Design Award Extreme precision, quality and innovation combined with ease of operation and practical handling are the key success factors of Microlife s blood pressure monitors. The blood pressure monitors BP A80, BP A100, BP A100 Plus, BP W100 and BP A6 PC have now been recognised with one of the world s highest design award, the «red dot» product design. German Design Award Microlife has been awarded with the «Special Mention» recognition by the German Design Council for the Blood Pressure Monitor BP A6 PC and the Non Contact Thermometer NC 150. The German Design Council is one of the world s leading centres of expertise on design. They support corporations in their brand and design development efforts and communicate the added value of design, both in Germany and beyond its borders. Environmental Protection Fulfilling our social and corporate responsibility means that we have to take environmental protection seriously, foster human health and help conserve natural resources. Through management leadership and employee commitment, we aim to conduct the manufacturing of our high quality healthcare solutions in a way that protects the environment. 2 Microlife A partner for people. For life.

3 Automatic blood pressure monitors SemiAutomatic and Manual blood pressure monitors Wrist blood pressure monitors Aneroids Stethoscopes Accessories WatchBP Professional Solutions Hypertension Management 4 Hypertension Atrial Fibrillation Pulse Arrhythmia Detection Inflation Mode Technology Microlife Average Mode Validation in Atrial Fibrillation Validation in pregnancy, preeclampsia Validation in endstage renal disease (ESRD) Validation in hypotension Nathan 2015 Validation on DABLWebsite Technologies / Validations 12 Technologies Infrared thermometers Pentype thermometers Special thermometers Fever Management 30 Fever Peak flow meter Nebulisers Pulse Oximeter Asthma Management 41 Asthma Heating pads Heating blanket Foot Warmer Flexible Heating 47 Flexible Heating Diagnostic scale Body fat scale Weight scale Weight Management 50 Weight

4 Hypertension Management Home Monitoring Blood Pressure Monitor with Stroke Risk Detection AFIB Touch BP A7 Touch Atrial fibrillation detection for stroke prevention Touch screen technology USB port, 2 users, and 99 memories per user BHS protocol: A/A in special population with atrial fi brillation Fully automatic Userfriendly touch screen technology Gentle + technology MAM technology: 3 readings in a row Conical rigid cuff wide range 2242 cm Traffic light indicator Cuff check indicator Arm movement indicator Lock/Unlock function Bluetooth Blood Pressure Monitor with Stroke Risk Detection AFIB Bluetooth BP A6 BT Atrial fibrillation detection for stroke prevention MAM technology: 3 readings in a row as recommended by doctors Bluetooth technology for easy analysis of your blood pressure BHS protocol: A/A in special population with atrial fi brillation Fully automatic Gentle + technology 99 memories, USB port Traffic light indicator Conical rigid cuff wide range 2242 cm Cuff check indicator Arm movement indicator Blood Pressure Monitor with Stroke Risk Detection AFIB PC BP A6 PC Atrial fibrillation detection for stroke prevention MAM technology: 3 readings in a row as recommended by doctors USB port, 2 users, and 99 memories per user BHS protocol: A/A in special population with atrial fi brillation Fully automatic Gentle + technology for gentle inflation and deflation Traffic light indicator Cuff check indicator Arm movement indicator Lock/Unlock function 4 Hypertension Management The Bluetooth word mark and logos are registered trademarks owned by Bluetooth SIG, Inc. and any use of such marks by Microlife Corp. is under license. Other trademarks and trade names are those of their respective owners.

5 BP A3L Comfort Advanced Blood Pressure Monitor with IMT Inflation Mode Technology MAM IMT Gentle measurement during inflation MAM technology: 3 readings in a row as recommended by doctors Large display Validations Hypertension ISO protocol Fully automatic 2 x 99 Data memory Traffic light indicator USB port Soft fanshaped cuff Time and date Cuff check indicator Arm movement indicator Advanced Technology Blood Pressure Monitor MAM Plus BP A3 Plus MAM technology: 3 readings in a row as recommended by doctors Comfortable cuff for all common arm sizes 2 users, and 99 memories per user BHS protocol: A/A in special population Fully automatic Gentle + technology for gentle inflation and deflation Traffic light indicator Soft fanshaped cuff Cuff check indicator Arm movement indicator Blood Pressure Monitor with Gentle + technology Automatic BP A2 Basic Comfortable cuff for all common arm sizes PAD technology for arrhythmia detection 30 Data memory BHS protocol: A/A Time and date Fully automatic Traffic light indicator Soft fanshaped cuff Cuff check indicator Arm movement indicator Blood Pressure Monitor with PAD technology Simple BP A2 Classic Comfortable cuff for all common arm sizes PAD technology for arrhythmia detection 30 Data memory BHS protocol: A/A Fully automatic Traffic light indicator Soft fanshaped cuff Low battery indication Hypertension Management 5

6 Blood Pressure Monitor with Gentle + technology Travel Kit Easy BP A1 Easy Comfortable cuff for all common arm sizes PAD technology for arrhythmia detection 1 touch operation, easy to use BHS protocol: A/A 1 Button, 1 Data memory Fully automatic Soft fanshaped cuff Arm movement indicator Blood Pressure Monitor with Stroke Risk Detection AFIB Automatic PC BP A200 AFIB Atrial fibrillation detection for stroke prevention MAM technology: 3 readings in a row as recommended by doctors USB port, memory for 200 measurements BHS protocol: A/A in special population Fully automatic USB port Conical rigid cuff wide range 2242 cm 200 Data memory Time and date Low battery indication Arm movement indicator Blood Pressure Monitor with Stroke Risk Detection AFIB BP A150 AFIB Atrial fibrillation detection for stroke prevention MAM technology: 3 readings in a row as recommended by doctors Comfortable cuff for all common arm sizes BHS protocol: A/A in special population Fully automatic Soft fanshaped cuff Traffic light indicator 1 Button, 1 Data memory Low battery indication Arm movement indicator Blood Pressure Monitor with Voice Feature Talking BP A130 Voice guided Certified quality with PAD Volume On/Off 6 languages BHS protocol: A/A in special population Fully automatic Soft fanshaped cuff Traffic light indicator 100 Data memory With speaker and volume control 6 Hypertension Management

7 Blood Pressure Monitor with MAM technology Automatic Plus Recommended by doctors 200 Data memory Medically reliable measurements with PAD & MAM Validations Hypertension BHS protocol: A/A BP A100 Plus Fully automatic Easy to use cuff Note panel XLDisplay & traffic light indication One touch operation 200 Data memory Low battery indication Rechargeable batteryfriendly Blood Pressure Monitor with PAD technology Automatic PAD Certified quality with PAD Recommended by doctors Accurate results at your fingertips BHS protocol: A/A BP A100 Fully automatic Easy to use cuff XLDisplay Note panel One touch operation 30 Data memory Washable cuff cover Low battery indication Rechargeable batteryfriendly Blood Pressure Monitor with PAD technology BP 3AG1 High accuracy 30 Data memory Certified quality with PAD BHS protocol: A/A BP 3AG1 Fully automatic One touch operation 30 Data memory Easy to use cuff Automatic switchoff Low battery indication Rechargeable batteryfriendly Hypertension Management 7

8 Blood Pressure Monitor with PAD technology SemiAutomatic BP N2 Easy Comfortable cuff for M size PAD technology for arrhythmia detection 1 touch operation, easy to use Blood pressure and pulse measurements Gentle warning for hypertension 1 Button, 1 Data memory Very easy to use Automatic switchoff Soft fanshaped cuff Blood Pressure Monitor SemiAutomatic BP 3AS12 BP 3AS12 High accuracy Recommended by doctors Automatic deflation Blood pressure and pulse measurements Last reading memory Very easy to use Automatic switchoff Clinically tested Blood Pressure Monitor SemiAutomatic BP A50 Reliable Recommended by doctors Certified quality with PAD BP A50 Blood pressure and pulse measurements 14 Data memory Easy to use cuff Large Display Low battery indication Clinically tested ESH protocol 8 Hypertension Management

9 BP W2 Slim Wrist Blood Pressure Monitor with IMT Inflation Mode Technology Slim Gentle measurement during inflation PAD technology for arrhythmia detection For wrist circumferences up to 23 cm Validations Hypertension cm ISO protocol Fully automatic Modern and slim design Easy to use 2 x 60 Data memory Time and date Traffic light indicator Portable Low battery indication Arm movement indicator Cuff check indicator Wrist Blood Pressure Monitor with PAD technology Wrist LED BP W1 Basic LED arm position indicator PAD technology for arrhythmia detection Very easy to use Fully automatic Portable 60 Data memory Time and date Traffic light indicator Large display Low battery indication Arm movement indicator Blood Pressure Monitor Wrist BP W100 BP W100 Compact and portable Recommended by doctors Equipped with PAD technology BHS protocol: A/A Fully automatic 200 Data memory Time and date 2 Alarm times With storage box Low battery indication Rechargeable batteryfriendly Hypertension Management 9

10 Comparison Product name BP A7 Touch BP A6 BT BP A6 PC BP A3L Comfort BP A3 Plus BP A2 Basic BP A2 Classic BP A1 Easy BP A200 AFIB BP A150 AFIB Type UAA UAA UAA UAA UAA UAA UAA UAA UAA UAA Page AFIB PAD MAM IMT Time & Date Positioning indicator Memory 2 x x 99 2 x 99 2 x Adapter port PC connection Traffic light Rechargeable battery friendly Product name BP A130 Talking BP A100 Plus BP A100 BP 3AG1 BP N2 Easy BP 3AS12 BP A50 BP W2 Slim BP W1 Basic BP W100 Type UAA UAA UAA UAA UAS UAS UAS wrist wrist wrist Page AFIB PAD MAM IMT Time & Date Positioning indicator Memory x Adapter port PC connection Traffic light Rechargeable battery friendly UAA = upper arm, automatic / UAS = upper arm, semiautomatic 10 Hypertension Management

11 AG110 Clinical High accuracy Competent solution Easy to use Highquality sphygmomanometer Professional cuff (without metal bar) Aneroid Blood Pressure Kit Bulb and valve Soft bag Validations Hypertension Basic High accuracy Complete solution Easy to use Aneroid Blood Pressure Kit AG120 Highquality sphygmomanometer Stethoscope Soft Msize cuff Bulb and valve Soft bag Economic Aneroid Blood Pressure Kit AG130 High accuracy Recommended by doctors Easy to use Highquality sphygmomanometer Stethoscope Soft Msize cuff Bulb and valve Soft bag Professional Palm Blood Pressure Kit AG140 High accuracy Precise deflation control Ergonomic operation Highquality sphygmomanometer Professional cuff (without metal bar) Stethoscope Bulb and valve Soft bag Hypertension Management 11

12 Stethoscope ST 71 Single Head High sound precision Reliable quality Lightweight chest piece Lightweight aluminum chest piece Adjustable chromeplated brass binaural Durable onepiece molded PVC «Y» tubing Ear tips with soft coneshaped bell ST 72 Dual Head High sound precision Reliable quality Lightweight chest piece Aluminum chest piece Dual head Adjustable chromeplated brass binaural Stethoscope Durable onepiece molded PVC «Y» tubing Ear tips with soft coneshaped bell Stethoscope Sprague Rappaport ST 77 Black Dark blue Grey Red Lilac High sound precision Reliable quality Accessories included 3 spare ear tips of different sizes 3 bell type chest pieces 2 spare transparent plastic diaphragms 5 colors Accessories AD1024C Mains adapter for Microlife products AD1024C / AD1024CW Adapter Suitable from V DC, Hz Use only with Microlife products AD1024CW Mains adapter for WatchBP Home Input: V DC, 50/60 Hz Output: 6 V, 600 ma 12 Hypertension Management

13 S M M L L L XL Soft fanshaped Upper arm cuff Soft cuff for the highest level of comfort Fanshaped for better fitting and accuracy Suitable for all common arm sizes Use only with Microlife products Available sizes: S: cm M: cm L: cm ML: cm LXL: cm Validations Hypertension ML Easy Upper arm cuff Wide range conical rigid arm circumference Easy to fit conical rigid shape cuff Highest level of comfort Cuffs, as important as the blood pressure monitor An appropriate cuff size and shape are the key elements for an accurate blood pressure measurement. Microlife has developed a new generation of cuffs, able to meet the needs of all patients. All Microlife blood pressure monitors are equipped with a guide to check the arm circumference in order to select the correct cuff size. Intuitive colorcoded connectors with integrated valve A regular cuff deflation speed is very important for accurate blood pressure measurement. Different cuff sizes have various deflation speeds. Blue Grey Black L Connector Black/Black Each Microlife cuff has a uniquely coded connector with integrated calibrated valve, that guarantees optimal deflation speed. Blue calibrated for S cuff Grey calibrated for M and M L cuff Black calibrated for L and L XL cuff L Connector suitable for use with: S/M/ML 3G cuffs on 2G devices, semiautomatic and IMTdevices Black/Black Connector suitable for use with: L/LXL 3G cuffs on 2G devices, semiautomatic and IMTdevices Clinically validated Microlife wide range conical cuff Microlife wide range cuffs (M L size and L XL size) fit both normal and large arms. The conical shape provides a better fit for improved accuracy. Microlife wide range cuffs are available in soft and rigid preformed structure (easy fit and comfort). Both cuffs are validated in specific clinical studies. 1 Latest materials: «Latex free and PVC free»* Microlife bladders are «latex free» to avoid any latex allergy problems. The innovative TPU (thermoplastic polyurethane) plastic bladder has replaced the traditional latex bladder. These TPU bladders provide a better durability than latex and PVC. All Microlife cuffs have a 2year guarantee. 1 Bonso E, Dorigatti F, Palatini P: Accuracy of the BP A100 blood pressure measuring device coupled with a single cuff with standardsize bladder over a wide range of arm circumferences. Blood Press Monit 2009; 14: 2169 * Cuff tube is PVC. Hypertension Management 13

14 Hypertension Management WatchBP Professional Solutions Ambulatory 24hour blood pressure measurement Office blood pressure measurement Selfmeasurement of blood pressure at home Population screening WatchBP Office AFIB Dualcuff blood pressure measurement Screening for AF with high accuracy Builtin auscultatory measurement function WatchBP Office AFIB Screen mode for identifying Routine mode HTN (Hypertension) for easily implementing IAD (Inter Arm Difference) BP measurement AF (Atrial Fibrillation) Auscultatory mode 3 consecutive Double arm measurements measurement AHA Protocol Embedded 14 Hypertension Management

15 Cardiovascular Screening Device WatchBP Office ABI Dualcuff blood pressure measurement Screening for AF with high accuracy Fast, easy and accurate Ankle Brachial Index (ABI) assessment Validations Hypertension WatchBP Office ABI AHA Protocol Embedded AF detection 3 consecutive measurements Double arm measurement ABI assessment Inter Arm Difference (IAD) assessment PC link Cardiovascular Screening Solution WatchBP Office Central Noninvasive central blood pressure measurement Screening for AF with high accuracy Fast, easy and accurate Ankle Brachial Index (ABI) assessment WatchBP Office Central AHA Protocol Embedded validated against simultaneously recorded invasively measured central aortic blood pressure measurement AF detection 3 consecutive measurements Double arm measurement ABI assessment Inter Arm Difference (IAD) assessment PC link Central blood pressure measurement Professional 24hour blood pressure monitor WatchBP O3 Ambulatory Fullyprogrammable Highly affordable Lightweight and compact WatchBP O3 Ambulatory AHA Protocol Embedded Convenient to carry PC link Easy setup Silent mode option Software CD included Nighttime measurement Pillbutton Reports in PDF / Excel Clinically validated Optional: AF detection Hypertension Management 15

16 BY RECOMMENDED National Health Service WatchBP O3 AFIB Professional 24hour blood pressure monitor Fullyprogrammable Screening for AF with high accuracy Lightweight and compact AHA Protocol Embedded WatchBP O3 AFIB AF detection PC link Easy setup Silent mode option Highly affordable Software CD included Nighttime measurement Pillbutton Reports in PDF / Excel Clinically validated AHA Protocol Embedded WatchBP Home Home blood pressure monitor with detection function WatchBP Home Accurate for use in pregnancy and preeclampsia Embedded ESH/AHA/BHS measurement guidelines Automated data tabulation displays averages for morning, evening and overall measurement 250 Data memory For use in pregnancy and preeclampsia Software: WatchBP Analyzer Home PC link Usual mode Diagnostic mode (7day selfmeasurement program) AHA Protocol Embedded WatchBP Home A NICE Home blood pressure monitor with atrial fibrillation detection function WatchBP Home A Screening for AF with high accuracy Embedded ESH/AHA/BHS measurement guidelines Automated data tabulation displays averages for morning, evening and overall measurement AF detection 3 consecutive measurements PC link Software: WatchBP Analyzer Home A 250 Data memory Usual mode Diagnostic mode (7day selfmeasurement program) 16 Hypertension Management

17 RECOMMENDED BY National Health Service Home blood pressure monitor with atrial fibrillation detection function WatchBP Home A BT (Bluetooth) Bluetooth technology for easy analysis of your blood pressure Screening for AF with high accuracy Embedded ESH/AHA/BHS measurement guidelines Validations Hypertension WatchBP Home A BT AHA Protocol Embedded NICE AF detection 3 consecutive measurements PC link Software: WatchBP Analyzer Home A BT 250 Data memory Usual mode Diagnostic mode (7day selfmeasurement program) Home blood pressure monitor with atrial fibrillation detection function WatchBP Home N Screening for AF with high accuracy Embedded ESH/AHA/BHS measurement guidelines For monitoring blood pressure during sleep AHA Protocol Embedded WatchBP Home N AF detection 3 consecutive measurements PC link Software: WatchBP Analyzer Home N 250 Data memory Usual mode Diagnostic mode (7day selfmeasurement program) Nighttime measurement Pillbutton Home blood pressure monitor with atrial fibrillation detection function WatchBP Home S WatchBP Home S Simultaneously detecting high blood pressure and AF conditions at home Animated reminder for seeking medical consultation Easy, reliable and affordable device AHA Protocol Embedded AF detection 3 consecutive measurements Easy Reliable Affordable The Bluetooth word mark and logos are registered trademarks owned by Bluetooth SIG, Inc. and any use of such marks by Microlife Corp. is under license. Other trademarks and trade names are those of their respective owners. Hypertension Management 17

18 Comparison WatchBP Office AF detection 3 consecutive measurements Double arm measurement Ausculatory mode ABI assessment PC link Central blood pressure measurement For use in end stage renal disease (ESRD) WatchBP Office AFIB WatchBP Office ABI WatchBP Office Central For use in pregnancy WatchBP O3 24hour ambulatory blood pressure monitoring AF detection Nighttime measurement Pill button PC link For use in end stage renal disease (ESRD) For use in pregnancy WatchBP O3 Ambulatory WatchBP O3 AFIB WatchBP Home Single measurement AF detection 3 consecutive measurements Nighttime measurement Pill button ESH/AHA/BHS guidelines embedded PC link For use in end stage renal disease (ESRD) For use in pregnancy Bluetooth WatchBP Home WatchBP Home A WatchBP Home A BT WatchBP Home N WatchBP Home S 18 Hypertension Management The Bluetooth word mark and logos are registered trademarks owned by Bluetooth SIG, Inc. and any use of such marks by Microlife Corp. is under license. Other trademarks and trade names are those of their respective owners.

19 The cardiovascular management solution Clinical blood pressure measurement has limited accuracy because of: Blood pressure variability White coat effect / hypertension Masked hypertension Additional cardiovascular screening is recommended for: Atrial fibrillation (AF) Peripheral arterial disease: Ankle Brachial Index (ABI) Inter Arm Difference (IAD) Validations Hypertension Guidelines recommend: Ambulatory (24hour) blood pressure measurement Selfmeasurement of blood pressure at home Microlife WatchBP presents a solution that makes screening for these important cardiovascular risks easy, fast and accurate. High accuracy and clinically validated AHA Protocol Embedded All tested Microlife WatchBP devices have passed ESH, BHS and AAMI / ISO validation protocols. Accuracy of WatchBP blood pressure monitors Over the past 10 years Microlife WatchBP devices have passed more than 20 validations according to both the ESH, BHS and AAMI / ISO protocols. These include validations for special patient groups such as patients with high blood pressure during pregnancy (preeclampsia), End Stage Renal Disease (ESRD) and for those with obesity. All WatchBP Home devices have ESH/AHA/BHS guidelines embedded. Recommended by NICE NICE RECOMMENDED BY National Health Service The National Institute for Health and Care Excellence (NICE) officially recommends using the WatchBP Home A during routine blood pressure measurement for all GP s in the United Kingdom. WatchBP Home A should be used for hypertension monitoring in primary care. NICE medical technologies guidance addresses WatchBP Home A: The available evidence suggests that the device reliably detects atrial fibrillation and may increase the rate of detection when used in primary care. WatchBP Home A should be considered for use in people with suspected hypertension and those being screened or monitored for hypertension, in primary care. Tested and approved for detecting atrial fibrillation WatchBP AFIB detects atrial fibrillation with high accuracy (sensitivity 98%, specificity 92%) as demonstrated in multiple comparative studies with ECG. Hypertension Management 19

20 Cuffs, as important as the blood pressure monitor Using the wrong size cuff is a major cause for erroneous blood pressure measurements. All cuffs are both latex and PVC free Soft Upper Arm WatchBP Office (Washable cuffs available in both nylon and cotton) WatchBP Home S S M M L L LXL* LXL* WatchBP O3 Ambulatory (Washable cuffs available in both nylon and cotton) S Tube with cuff connector M L 50 cm tube with cuff connector LXL* 100 cm tube with cuff connector * the LXL cuff has been validated for use among patients with large arms. 20 Hypertension Management

21 Rigid Upper Arm WatchBP Office ML With air tube 130 cm for: WatchBP Office AFIB, Office ABI, Office Central Validations Hypertension Upper Arm Single Patient Use (Disposable) WatchBP S Tube with cuff connector 1722cm Inches M 50 cm tube with cuff connector L 3242cm Inches 100 cm tube with cuff connector Soft Ankle WatchBP Office ABI / Central M Tube with cuff connector L 170 cm tube with cuff connector Upper arm cuff Ankle cuff Size Measures (cm) Measures (Inches) S M ML L LXL M L Hypertension Management 21

22 Premium Microlife Accuracy 1 ESH Protocol BHS protocol: A/A ISO protocol in Europe in special population Tested by European Society of Hypertension Microlife Blood Pressure Monitors are successfully validated according to the International Protocol of the ESH (European Society of Hypertension). Tested by British Hypertension Society Microlife Blood Pressure Monitors are successfully validated according to the protocol of the BHS (British Hypertension Society). The majority of Microlife s upper automatic arm devices are validated with the highest possible grade of A/A. Tested by ANSI/AAMI/ISO Microlife Blood Pressure Monitors are successfully validated according to the ANSI/AAMI/ ISO :2013 protocols. Tested in Europe In cooperation with an Austrian Hospital several studies have been conducted proving the accuracy and reliability of our infrared thermometers. Tested in special population Clinically tested on patients with pregnancy/preeclampsia, diabetes, renal disease, obesity and atrial fibrillation. Tested by German Hypertension Society It is the aim of the German Hypertension Society to improve measurement accuracy, by testing and awarding Blood Pressure Monitoring devices that fulfill its own test criteria following the strict protocol of the German Hypertension Society. European Society of Hypertension The main purpose of the European Society of Hypertension (ESH) is to provide a stable and organised European platform for scientific exchange in hypertension. The objectives of ESH are to promote, endorse and organise activities involved with the continuing medical education in the field of hypertension and associated cardiovascular diseases. Microlife exhibits its products at each congress. 1 The permission for the use of the ESH logo is provided only to Microlife as a company. No distinct product. It is not allowed to use the logo in own printed leaflets with products other than Microlife. Violation of this copyright law may lead to legal issues where Microlife won t take any responsibility for. 22 Premium Microlife Accuracy

23 Advanced Microlife Technologies Atrial Fibrillation US 7,680,532 US 7,020,514 US 7,706,868 Atrial Fibrillation (AF) is a growing and urgent public health concern. AF is the most common sustained abnormal heart rhythm worldwide and numbers set to increase. About 20% of strokes occur in patients with AF. AF often is accompanied by additional risk factors such as hypertension and diabetes mellitus. Therefore, Microlife developed Hypertension and Atrial Fibrillation are the major risk factors of STROKE. Microlife AFIB, the blood pressure monitor with Atrial Fibrillation detection. blood pressure monitors with an implemented AF detector the socalled AFIB technology. This means that AF can be diagnosed during blood pressure measurement without any extra efforts. With the implemented AF detector Microlife follows the latest guidelines of the European Society of Hypertension (ESH) for home blood pressure monitoring. Technologies How Microlife s patented AFIB technology works Microlife s patented AFIB technology performs AF screening with the oscillometric method during easy blood pressure measurements. An algorithm calculates the irregularity index, which is the standard deviation divided by mean based on interval times between heartbeats. If AF is detected during blood pressure measurements, the AFIB symbol is displayed. Microlife AFIB does not make a diagnosis, but provides important information for your doctor, who can refer you to a 12lead ECG to confirm the presence of AF. Tested and approved to detect atrial fibrillation Microlife AFIB detects AF with high accuracy (on average, sensitivity 98% specificity 92%) as demonstrated in several comparative studies with ECG. Patients (n) Setting Average age (y) AF n (%) NonAF arrhythmia n (%) Sensitivity (%) Specificity (%) Wiesel Hospital (12) (±25) Stergiou Hospital (37) 23 (31) Wiesel Hospital (23) 64 (14) Oxford trial Primary care practice (11) n.s Tripps study Home (10) n.s. 99* 93* Wiesel Hospital (15) n.s Gandolfo Hospital (38) n.s [1] Wiesel J et al, Detection of Atrial Fibrillation using a modified microlife blood pressure monitor. Am J Hypertens 2009: 22845:852 [2] Stergiou, G.S., et al., Diagnostic accuracy of a home blood pressure monitor to detect atrial fibrillation. J Hum Hypertens, : p [3] Wiesel, J., et al., Detection of atrial fibrillation using a modified microlife blood pressure monitor. Am J Hypertens, : p [4] Kearley, K., et al., What is the best way to screen for atrial fibrillation in primary care? A comparison of the accuracy of 3 methods: nurse pulse palpation, a handheld ECG and a modified BP monitor Submitted, [5] Wiesel, J., et al., Screening for Asymptomatic Atrial Fibrillation While Monitoring the Blood Pressure at Home: Trial of Regular Versus Irregular Pulse for Prevention of Stroke (TRIPPS 2.0). Am J Cardiol, [6] Wiesel J, Arbesfeld B, Schechter D. Comparison of the Microlife blood pressure monitor with the Omron blood pressure monitor for detecting atrial fibrillation. Am J Cardiol 2014;114: [7] Gandolfo C, Balestrino M, Bruno C, Finocchi C, Reale N: Validation of a simple method for atrial fibrillation screening in patients with stroke. Neurol Sci 2015; 36: 16758: All studies were compared against 12lead ECG unless otherwise indicated; AF indicates atrial fibrillation; n.s., not specified; *, compared against electrocardiographic event monitor. Advanced Microlife Technologies 23

24 Pulse Arrhythmia Detection US Patent 6,485,429 B2 The PAD technology automatically detects heart arrhythmias during a blood pressure measurement. What is PAD technology? The PAD technology (Pulse Arrhythmia Detection) analyses pulse frequency and detects irregular heart beats during blood pressure measurement. If an irregular heart beat occurs during the measurement, the PAD symbol is displayed. PAD does not replace a cardiac examination, but it serves to detect pulse irregularities at an early stage. Advantages of PAD technology All Microlife blood pressure monitors with PAD technology detect heart arrhythmias during a blood pressure measurement. This is automatically done by the device without the need for any adjustments. Unlike most common monitors, Microlife devices can distinguish between arrhythmias and artefacts due to great technical and physiological precision in measurements. Inflation Mode Technology IMT for fast, accurate and extra comfortable blood pressure measurements. What is IMT? Microlife IMT (Inflation Mode Technology) ensures an extra gentle, quick and accurate blood pressure measurement. IMT blood pressure devices examine pulse signals during inflation of the cuff. For assessing the blood pressure values, most automated blood pressure monitors analyse pulse oscillations during deflation of the cuff. Therefore, these devices must inflate mmhg above the estimated blood pressure level, which from experience the user may find uncomfortable in cases where a high cuff inflation pressure is required. In order to guarantee that IMT blood pressure monitors also meet our highest standards, the inflation runs smoothly and slowly. As soon as all necessary signals are recorded, the air in the cuff is discharged and the blood pressure value is immediately displayed so that the average measurement time is significantly shortened. This in combination with the gentle inflation process guarantees a new level of comfort. Patients who generally experience a high cuff pressure as uncomfortable, will especially benefit from this technology. Advantages of IMT Accurate measurement results Particularly pleasant, gentle measurement Shortened measurement time New level of comfort for blood pressure measurements 24 Advanced Microlife Technologies

25 Microlife Average Mode US Patent 6,447,457 B1 The MAM technology allows rapid and accurate characterisation of blood pressure equivalent to repeated measurements over 90 minutes. publication source: Wilton A, De Greeff A, Shennan AH RAPID ASSESSMENT OF BLOOD PRESSURE IN THE OBSTETRIC DAY UNIT USING MICROLIFE MAM TECHNOLOGY; European Society of Hypertension, 16th Annual Meeting, Madrid, Spain, June What is MAM technology? MAM (Microlife Average Mode) is the analysis of 3 successive measurements in less than 3 minutes so that superior reliability is achieved by automatic weighted data. MAM technology provides highest accuracy for blood pressure monitoring both at home and in professional settings. Multiple readings give important information to doctors and ensures that treatment plans meet healthcare needs. Technologies Why MAM technology? Doctors and hypertension societies recommend taking at least two readings every time and average the measurement value, because blood pressure fluctuates during the day. Microlife s patented MAM technology performs three consecutive measurements in every session. The readings are analysed and weighted for a more accurate result and the average blood pressure value is provided. Advantages of MAM technology High data reliability Efficient hypertension diagnosis Secured therapy control Compensation for insufficient rest prior to measurements Push the button 1 st Measurement 15 2 nd Measurement 15 3 rd Measurement* Analysis Result * A fourth measurement is automatically taken, if one of the individual measurements was questionable. Advanced Microlife Technologies 25

26 Validations Clinical validations confirm Microlife s leading accuracy 2001 Quality Seal German Hypertension League: Prof. M. Anlauf; Reinkenheide Hospital, Bremerhaven, Germany 2002 Prof. A. Shennan; St. Thomas Hospital, London, UK Blood Pressure Monitoring Journal, 2002, Vol. 7, No Dr. K.W. Forstner; Research Institute, Asperg, Germany, Pulse Arrhythmia Detection by Oscillometric Blood Pressure Measurement Devices, P25, American Society of Hypertension, 18th Annual Scientific Meeting, NYC, New York 2004 Reinders A, Cuckson AC, Lee J and Shennan AH, International Society of Hypertension,20th Annual Scientific Meeting Sao Paulo, Brazil 2005 Prof. Asmar, El Assaad; The Cardiovascular Institute, Paris, France Blood Pressure Monitoring Journal, 2005, Vol. 10, No Dr. Stergiou; Hypertension Centre Athens, Greece Blood Pressure Monitoring Journal, 2006, Vol. 11, No Prof. A. Shennan; St. Thomas Hospital, London, UK Blood Pressure Monitoring Journal, 2007, Vol. 25, No. 2, pp Dr. T. Pickering; Columbia University, New York, USA Blood Pressure Monitoring Journal, 2007, Vol. 12, No. 4, pp Dr. Stergiou; Hypertension Centre Athens, Greece Blood Pressure Monitoring Journal, 2007, Vol. 12, pp Dr. Stergiou; Hypertension Centre Athens, Greece Blood Pressure Monitoring Journal, 2008, Vol. 13, pp Dr. Stergiou; Hypertension Centre Athens, Greece Blood Pressure Monitoring Journal, 2009, Vol. 23, pp Prof. Paolo Palatini; Università di Padova, Italia Blood Pressure Monitoring Journal, 2009, Vol. 14, pp F. Ragazzo, F. Saladini, P. Palatini Blood Pressure Monitoring Journal, 2010, Vol. 15, pp S. Madiero, F. Saladini, E. Benetti, P. Palatini Blood Pressure Monitoring Journal 2011, Vol. 16, pp Kearley K, Selwood M, Van den Bruel A, et al. BMJ Open 2014;4:e doi: /bmjopen Gandolfo C, Balestrino M, Bruno C, Finocchi C, Reale N: Validation of a simple method for atrial fibrillation screening in patients with stroke. Neurol Sci 2015; 36: 16758: Nathan HL, de Greeff A, Hezelgrave NL, Chappell LC, Shennan AH: Accuracy validation of the Microlife 3AS12 blood pressure device in a pregnant population with low blood pressure. Blood Pressure Monitoring 2015 Oct;20(5): Bing S, Chen K, Hou H, Zhang W, Li L, Wei J, Shu C, Wan Y: Accuracy validation of the Microlife BP A200 Comfort and W2 Slim automated blood pressure monitors in a general adult population according to the European Society of Hypertension and the ANSI/AAMI/ ISO :2013 protocols. Blood Pressure Monitoring 2016 Apr; 21 (2): Validation in Atrial Fibrillation (AF) All Microlife fully automated upper arm blood pressure monitors can be used in patients with AF. Measurement of blood pressure in patients with AF is considered as difficult and uncertain. 1 Even auscultatory measurements obtained with a mercury device, regarded as the gold standard for blood pressure measurement, show large differences between and within different observers in the presence of atrial fibrillation. 1 All Microlife devices have proven to be accurate in measuring systolic blood pressure in patients with AF. 1 One particular study with the aim to assess the accuracy of blood pressure monitors for patients with atrial fibrillation highlight the importance of accurate measurements of systolic blood pressure for selfhome monitoring: Since atrial fibrillation affects mainly the elderly population in whom systolic blood pressure carries most of the hypertension induced cardiovascular risk, this device [BP A100 Plus] appears to be suitable for selfhome blood pressure monitoring in AF patients. 2 G.S. Stergiou, A. Destounis, A. Kollias, D. Tzamouranis, N. Karpettas, P. Kalogeropoulos et al. 1 Stergiou GS, Kollias A, Destounis A, Tzamouranis D: Automated blood pressure measurement in atrial fibrillation: a systematic review and metaanalysis. J Hypertens 2012; 30: Stergiou GS, Destounis A, Kollias A, Tzamouranis D, Karpettas N, Kalogeropoulos P: et al. Accuracy of automated oscillometric blood pressure measurement in patients with atrial fibrillation [abstract]. J Hypertens 2011; 29 (Suppl A):e2. 26 Validations

27 Validation in pregnancy Preeclampsia All Microlife fully automated upper arm blood pressure monitors can be used during pregnancy and preeclampsia. Common electronic blood pressure monitors have significant difficulties in measuring during pregnancy and especially during preeclampsia. This means that, when measurements are taken with these devices, preeclampsia may NOT be detected. For this reason healthcare authorities require a specific validation test among pregnant women and those who have preeclampsia before automated blood pressure devices may be recommended for use during pregnancy. Risks of preeclampsia Preeclampsia can reduce the blood flow through the placenta so that the baby receives less oxygen and nutrients. This can cause low birth weight and other problems for the baby. Most women with preeclampsia still deliver healthy babies. A few develop a condition called eclampsia, which causes high risk for both mother and baby. Preeclampsia can be recognised by a clear increase in blood pressure after 20 or 32 weeks of gestation. Microlife has produced today s only monitor with appropriate cuff sizes that can be recommended for use during pregnancy. 1 Reinders A, Cuckson AC, Lee JTM, Shennan AH 1 Reinders A, Cuckson AC, Lee JTM, Shennan AH: The Microlife 3BTOA: An accurate automated device for use in adults and pregnancy. Journal of Hypertension 2004; 22: S192S192: Validations Validation in endstage renal disease (ESRD) All Microlife fully automated upper arm blood pressure monitors can be used for patients with endstage renal disease and arterial stiffness. 1,2 Studies to date have shown that many oscillometric devices are not accurate in patients with diabetes and increased arterial stiffness. Patients with ESRD commonly suffer from increased arterial stiffness which as in other populations could affect the accuracy of oscillometric blood pressure devices used by these patients. This sometimes leads to an underestimated blood pressure value of up to 50 mmhg. 1 Aliza M. Thompson, Kazuo Eguchi, Michael E. Reznik, Samir S. Shah, Thomas G. Pickering: Validation of an oscillometric home blood pressure monitor in an endstage renal disease population and the effect of arterial stiffness on its accuracy, BPM: Blood Pressure Monitoring, Vol 12, N 4, pp , August Aliza M. Thompson, Kazuo Eguchi, Michael E. Reznik, Samir S. Shah, Thomas G. Pickering: Accuracy of a Home Blood Pressure Monitor Tested in Endstage Renal Disease Patients, ERD: European Renal Disease 2007, Issue 1, pp. 38/40 Validation in hypotension Nathan 2015 All Microlife upper arm blood pressure monitors can be used in hypotension (low blood pressure) and in hypotension during pregnancy. 1 Low blood pressure (BP) is the second most common cause of maternal deaths in pregnancy. 2 Many oscillometric devices fail to accurately measure low blood pressure values which can put both mother and child at risk. Therefore, it is important to test blood pressure monitors for accuracy in pregnant women with low blood pressure values (hypotension). The Microlife BP 3AS12 is the first device that is validated for measuring low blood pressure in pregnancy and received «A/A from BHS», the highest grade of accuracy. 1 Microlife has the first device to be both accurate in pregnancy and suitable for use in lowresource settings. 1 Nathan HL, de Greeff A, Hezelgrave NL, Chappell LC, Shennan AH 1 Nathan HL, de Greeff A, Hezelgrave NL, Chappell LC, Shennan AH: An accurate semiautomated oscillometric blood pressure device for use in pregnancy (including preeclampsia) in a lowincome and middleincome country population: the Microlife 3AS12. Blood Press Monit 2015; 20: Horton R. Healthy motherhood: an urgent call to action. The Lancet 2006; 368:1129. Validations 27

28 Validations on dablwebsite The dabl Educational Trust Limited was established by William J. Rickard and Prof Eoin O Brien in 2003 to oversee the website as a notforprofit educational venture. Manual Devices: Device Mode AAMI BHS ESH Circumstance Recommendation Microlife BP 3AS12 Electr Pass At rest Recommended 10 Microlife WatchBP Office Electr Pass At rest Recommended 8 Status as of October 14, 2016 Automated Upper Arm Devices for Self Measurement of Blood Pressure: Device Mode AAMI BHS ESH Circumstance Recommendation Microlife BP A1 Easy A/A Pass BP A100 Plus and BP 3BT0A Equivalences Osc Pass A/B Normotensive Pregnancy Recommended E106 Pass B/B Nonproteinuric HBP Pass A/B PreEclampsia Microlife BP A2 Classic A/A BP 3BT0A Equivalence Osc Pass BP A100 Equivalence Recommended E150 Microlife BP A2 Basic A/A Pass BP A100 Plus and BP 3BT0A Equivalences Osc Pass A/B Normotensive Pregnancy Recommended E107 Pass B/B Nonproteinuric HBP Pass A/B PreEclampsia Microlife BP A6 PC A/A Pass BP A100 Plus and BP 3BT0A Equivalences Osc Pass A/B Normotensive Pregnancy Recommended E108 Pass B/B Nonproteinuric HBP Pass A/B PreEclampsia Microlife BP 3AC11 Pass At rest Recommended 15 Osc Pass A/A Pregnancy; Abstract Questionable 20 Pass B/A Preeclampsia; Abstract Questionable 20 Microlife BP 3AC11 PC Osc Pass BP 3AC11 Equivalence Recommended E1 Pass ESRD population Recommended 28 Microlife BP 3AC12 Osc Pass BP 3AC11 Equivalence Recommended E2 Microlife BP 3AG1 Osc A/A BP 3BT0A Equivalence Recommended E3 Microlife BP 3BTO1 Osc A/A BP 3BT0A Equivalence Recommended E4 Microlife BP 3BTOA A/A Small recruitment violation Recommended 7 Osc Pass A/B Normotensive Pregnancy Pass B/B Nonproteinuric HBP Recommended 12 Pass A/B PreEclampsia Microlife BP 3BTOA(2) Osc A/A BP 3BT0A Equivalence Recommended E5 Microlife BP 3BTOAP Osc A/A BP 3BT0A Equivalence Recommended E6 Microlife BP A150 Afib Pass BP A100 Equivalence Osc Pass BP A100 Plus Equivalence Recommended E Validations

29 Device Mode AAMI BHS ESH Circumstance Recommendation Microlife BP A100 Osc Microlife BP A100 Plus Osc Pass BP A100 Plus Equivalence Recommended E7 Pass With ML Soft Cuff Recommended FTS, 52 Pass With ML Rigid Conical Cuff Recommended 37 Pass At rest Recommended 17 Pass At rest Recommended 29 Microlife Exact BP (BP3MD13) Osc Pass BP A100 Equivalence Recommended E21 Microlife RM 100 Osc A/A BP 3BT0A Equivalence Recommended E8 Microlife WatchBP Home Pass At rest Recommended 25 (BP3MX11) Osc A/A Pregnancy Recommended 66 B/A PreEclampsia Recommended 66 Microlife WatchBP Osc Pass Watch BP Home Equivalence Recommended E27 Home A (BP3MX13) Microlife WatchBP Osc Pass Watch BP Home Equivalence Recommended E70 Home N (BP3MX14) Microlife WatchBP Home S (BP3MX15) Osc Pass Watch BP Home Equivalence Recommended E28 Validations Automated Devices for Clinical Use and ABPM: Device Mode AAMI BHS ESH Circumstance Recommendation Microlife BP 3AS12 Pass At rest Recommended 34 Osc A/A Pregnancy Recommended 68 B/A PreEclampsia Recommended 68 Microlife WatchBP O3 Osc Pass At rest Recommended 38 (3MZ0) Microlife WatchBP O3 Osc Pass At rest Recommended 39 (3MZ1) Microlife WatchBP Office Osc Pass At rest Recommended 33 Microlife WatchBP Office Osc ABI Pass A/A Pass At rest Recommended Pass LXL size cuff Recommended 45 Microlife WatchBP Office Electr Pass WatchBP Office Equivalence Recommended E29 AFIB Microlife WatchBP Office Target Electr Pass BP A100 Equivalence Recommended E37 42 FTS Wrist Devices for Self Measurement of Blood Pressure: Device Mode AAMI BHS ESH Circumstance Recommendation Microlife BP W100 Wrist Pass A/A Pass Supine position Recommended 23 Microlife BP W2001 Wrist Pass MAM averaging and supine Recommended 21 position References: Please find the references for the validations on the dablwebsite: Validations 29

30 Fever Management Forehead Thermometer 3 Blue tracking light Non Contact Touchfree measurement Recommended by doctors Gentle & hygienic NC 150 Mercury free Fever alarm Illuminated display Beeper Blue tracking light 30 Data memory C F Switchable Multifunctional 3 Fever alarm Silent Glow TM Technology Measure body temperature Measure object temperature Instant Thermometer 1 Illuminated probe Ear Very easy to use Recommended by doctors Accurate results in only 1 second IR 150 Mercury free Fever alarm Illuminated display Beeper Blue probe LED 30 Data memory C F Switchable Multifunctional 1 Fever alarm Silent Glow TM Technology Measure body temperature Measure object temperature 30 Human Fever Management

31 Non Contact Thermometer 3 NC 100 Touchfree measurement Recommended by doctors Gentle & hygienic 3 NC 100 Fever alarm Silent Glow TM Technology Multiple use: body, object and ambient temperature measurement Silent Glow TM technology Illuminated display / backlight Very large LCD display 30 Data memory Fever alarm Storage base & bag Automatic switchoff Beeper Easy to use / read Infrared Ear Thermometer 1 IR 120 Very easy to use Recommended by doctors Accurate results in only 1 second 1 IR 120 Fever alarm Silent Glow TM Technology 1 second measurement Probe cover free Multiple use C Silent Glow TM technology Illuminated display / backlight Large LCD display Fever alarm Beeper 12 Data memory Measurement accuracy ± 0.2 C / ± 0.4 F Automatic switchoff Easy to use / read Storage case Fever Dual Mode Thermometer 1 1 IFR 100 Fever alarm Silent Glow TM Technology IFR 100 For the whole family Recommended by doctors Accurate & multifunctional Multiple use: ear, forehead and ambient temperature Silent Glow TM technology Illuminated display / backlight Large LCD display 12 Data memory Fever alarm Storage bag Automatic switchoff Beeper Easy to use / read Human Fever Management 31

32 Gold Tip Thermometer Swift 3 MT 550 Extra fast measurement Silent Glow TM Technology Flexible tip 4 5 GOLD TEMP TM no nickel in direct contact with the skin. Hg 10 Second measurement Flexible tip / soft touch Gold Tip anallergic 1 Large display Silent Glow TM technology Waterproof Antimicrobial Thermometer Fast Beeper Fever alarm Memory Automatic switchoff Low battery indication WORLD S FIRST antimicrobial thermometer Hg MT Second measurement High safety to whole family Protects against pathogenic microbes 10 Second measurement Reduces drastically the dispersion of contagious microorganisms Fights contamination among users Flexible tip / soft touch Large display Backlight Beeper Fever alarm Memory Low battery indication GOLD TEMP TM 6 Hg MT no nickel in direct contact with the skin. Fast Gold Tip Thermometer HighSpeed Highest accuracy in only 10 seconds Soft, flexible & safe measuring tip Baby friendly 10 Second measurement Flexible tip / soft touch Gold tip anallergic 1 Large display Backlight Waterproof Beeper Fever alarm Memory Measurement accuracy ±0.1 C / ± 0.2 F Automatic switchoff Automatic selftest Low battery indication Human Fever Management

33 Curved Design Thermometer 10Second MT Second measurement Curved design Flexible tip Hg 10 Second rectal measurement Flexible tip / soft touch Large display Waterproof Beeper Memory Measurement accuracy ±0.1 C / ± 0.2 F Automatic switchoff Automatic selftest Low battery indication Basic Digital Thermometer 30 1 MT Second measurement 100 % Waterproof Easy battery change Hg Second measurement Mercury free Waterproof Beeper Digital Thermometer Flexible Memory C F switchable Automatic switchoff Low battery indication 30 Fever 3 1 MT Second measurement 100 % Waterproof Flexible tip MT Hg Hg 60 MT Second measurement Flexible tip / soft touch Mercury free Waterproof, beeper Digital Thermometer Children Mercury free solution Flexible tip Last measurement memory 30 Second measurement Childfriendly designs Flexible tip / soft touch Mercury free Memory C F switchable Automatic switchoff Low battery indication 30 Memory Beeper Automatic switchoff Low battery indication Human Fever Management 33

34 Hg WORLD S FIRST antimicrobial thermometer GOLD TEMP TM Hg MT no nickel in direct contact with the skin. 60 Hg MT MT Antimicrobial Thermometer Easy Safe measurement Fights contamination Protects against pathogenic microbes 60 Second measurement Reduces drastically the dispersion of contagious microorganisms Swift Digital Thermometer Mercury free solution High accuracy Gentle & hygienic 60 Second measurement Water resistant, beeper Memory Automatic switchoff Digital Thermometer Gold Tip Easy battery change Flexible & soft touch Automatic switchoff & selftest 60 Second measurement Flexible tip / soft touch Gold tip anallergic 1 Waterproof, beeper Memory 60 Memory, beeper Automatic switchoff Automatic selftest Low battery indication 60 Measurement accuracy ±0.1 C / ± 0.2 F Automatic selftest Low battery indication 60 Measurement accuracy ±0.1 C / ± 0.2 F Automatic switchoff Automatic selftest Low battery indication Transparent Thermometer Smart Mercury free solution Compact & easy to use Last measurement memory 60 Hg 60 MT Second measurement No metal tip anallergic Waterproof Easy to clean Memory Measurement accuracy ±0.1 C / ± 0.2 F Automatic switchoff Automatic selftest Low battery indication 34 Human Fever Management

35 Right choice of thermometers Internal body temperature External body temperature Measurement method Normal temperature range Medical indication Recommended thermometers Rectal Oral Ear Axillary Forehead / Non Contact C C C C C Fast and precise measurement that is used for reference values. It is used frequently with babies and infants. Special attention on hygiene needs to be given. 10, 30 or 60 Second thermometer: e.g. MT 550, MT 700 Fast and convenient measurement that supplies accurate values. Special attention during measurement needs to be given as mouth temperature may be changed by cold / hot beverages or open mouth respiration. 10, 30 or 60 Second thermometer: e.g. MT 410, MT 500 Fast and convenient measurement of core body temperature. Very accurate results can be obtained. To achieve reliable measurements instructions must be kept and a little practice is needed. Infrared ear thermometer: e.g. IR 150, IFR 100 Practical and comfortable as application in the shoulder cave is easily accessible and simple. The measurement time is long and results can underestimate body core temperature. 60 Second thermometer: e.g. MT 300, MT 1931, MT 3010 Fast and hygienic measuring method. Measuring site is easy to reach and the measurement can be performed even on a sleeping baby. During decreased skin blood circulation reduced accuracy. Sweat needs to be removed. Infrared non contact or forehead thermometer: e.g. NC 150 Babies and children up to 3 years This is the ideal measurement method as it supplies very accurate results in a relatively short time. This measurement is not suitable as it can provide inaccurate results in this age group due to open mouth respiration and crying. For children from about 6 months on this is a good alternative to rectal measurement as it provides very fast and accurate results. Read the instructions carefully. This measurement method is not suitable as it is likely to provide inaccurate results in this age group due to application difficulties. This measurement me thod is a good alternative if the child is very sensitive to other types of thermometers, has an ear infection or is sleeping. Fever Children above 3 years and adults Due to convenience and ethical reasons this method is rather not used on older children and adults. This measurement method is a good option as it is very simple and fast. Relatively accurate results can be achieved if performed correctly. Ear temperature measurement is a convenient choice as it provides good results in a short time and the measuring site is easily accessible. Axillary temperature determination is very easy and convenient. Yet for obtaining highly accurate results another measurement method should be chosen. This measurement me thod is very convenient, easy and fast. In addition, it provides accurate re sults and is therefore a recommendable way of temperature measurement. Icons Easy to read icons: Blue tracking light Illuminated probe Date & Time 1 1 Second measurement 10 Second measurement Waterproof Memory High temperature indication Silent Glow TM technology Second measurement Beeper Fever alarm Flexible Tip Illuminated display Hg Mercury free solution Clinically tested in Europe Human Fever Management 35

36 Comparison Product name Non Contact Ear Non Contact Ear Dual Mode Swift Fast High Speed 10 Second Basic Model name NC 150 IR 150 NC 100 IR 120 IFR 100 MT 550 MT 410 MT 200 MT 1961 MT 500 Infrared technology Sensor tip technology Measurement time / Forehead measurement Non contact measurement Ear measurement Object ambient measurement Rectal, oral, and axillary measurement Illuminated probe Clean me function Tracking light technology Flexible tip Goldplated tip (anallergic) No metal tip (anallergic) Antimicrobial properties Nickel tip Silent Glow TM technology Fever alarm Beeper Display incl. date & time Large display Display backlight Waterproof Battery 2 x 1.5 V; size AAA CR V 2 x 1.5 V; size AAA CR V CR V CR V 1.5/1.55 V; R /1.55 V; R /1.55 V; R 41 Low battery indication Replaceable battery Automatic selftest Automatic switch off After 1 min. After 1 min. After 1 min. After 1 min. After 1 min. After 3 min. After 10 min. After 10 min. After 10 min. Memory Measurement range 0 C to C 0 C to C 0 C to C 0 C to C 0 C to C 32 C to 43.9 C 32 C to 42.9 C 32 C to 42.9 C 32 C to 42.9 C 1.5/1.55 V; R 41 After 10 min. 32 C to 42.9 C Measurement accuracy ± 0.2 C ± 0.2 C ± 0.2 C ± 0.2 C ± 0.2 C ± 0.1 C ± 0.1 C ± 0.1 C ± 0.1 C ± 0.1 C Mercury free Product warranty 5 years 5 years 2 years 2 years 2 years Lifetime 5 years Lifetime Lifetime Lifetime 36 Human Fever Management

37 Comparison Product name Flexible Children Children Easy Swift Gold Tip Smart Pen Type Compact Model name MT 510 MT 700 MT 710 MT 3010 MT 300 MT 1931 MT 50 MT 16F1 MT 1671 Infrared technology Sensor tip technology Measurement time Forehead measurement Non contact measurement Ear measurement Object ambient measurement Rectal, oral, and axillary measurement Illuminated probe Clean me function Tracking light technology Flexible tip Goldplated tip (anallergic) No metal tip (anallergic) Antimicrobial properties Nickel tip Fever Silent Glow TM technology Fever alarm Beeper Display incl. date & time Large display Display backlight Waterproof Battery 1.5/1.55 V; R /1.55 V; R /1.55 V; R /1.55 V; R /1.55 V; R /1.55 V; R /1.55 V; R /1.55 V; R 41 Low battery indication Replaceable battery Automatic selftest Automatic switch off After 10 min. After 10 min. After 10 min. After 10 min. After 10 min. After 10 min. After 10 min. After 10 min. Memory Measurement range 32 C to 42.9 C 32 C to 42.9 C 32 C to 42.9 C 32 C to 43.9 C 32 C to 42.9 C 32 C to 43.9 C 32 C to 43.9 C 32 C to 43.9 C 1.5/1.55 V; R 41 After 10 min. 32 C to 43.9 C Measurement accuracy ± 0.1 C ± 0.1 C ± 0.1 C ± 0.1 C ± 0.1 C ± 0.1 C ± 0.1 C ± 0.1 C ± 0.1 C Mercury free Product warranty Lifetime Lifetime Lifetime 5 years Lifetime Lifetime Lifetime Lifetime Lifetime Human Fever Management 37

38 Fever technologies Silent Glow TM Technology Fever alarm Illuminated Fever alarm. Microlife is the first company in Europe to launch the Silent Glow TM Technology, enabling easy readability of high temperatures. All Microlife infrared thermometers use this registered Swiss trademarked Silent Glow TM Technology. A green light will show if temperatures are up to 37.4 C A red light will show if temperatures exceed 37.4 C 1Second Technology Trademark No (CH) Microlife has developed a new 1second IR Ear Thermometer that uses «realtime» technology. This new patented technology ensures superior accuracy. 1 How does Microlife s Ear thermometer ensure superior performance? The heat sensor is located at the front of the measurement tip and thus closer to your body s heat source. A patented tip design prevents false readings from the effects of room temperature. Our high quality ear sensor provides years of reliable readings. 3Seconds Technology Microlife uses the 3second Non Contact (NC) thermometers for fast, reliable and hygienic measurements on the forehead. 3 How does Microlife's NC thermometer ensure accurate readings? Being able to measure the center of the forehead during the 3second measurement time ensures maximum precision. Microlife's NC thermometers measure 12 times per second and the readout displays the highest value of the 36 spots measured. This technology guarantees safe and sanitary measurements within only 3 seconds. 10Seconds Technology Trademark No (CH) Microlife s new 10seconds highspeed technology is part of our newest Digital Thermometers. An advancement in the design and assembly of the measuring tip (patent) allows for temperature measurement in as little as 10seconds, more than 4 times faster than conventional digital thermometers. Maximum precision and accuracy of temperature measurement are achieved through the use of microcomputer technology in the advanced sensor tip. The Microlife sensor tip is a very unique piece of technology which is protected by a patent. Antimicrobial Thermometer with Copper Alloy WORLD S FIRST antimicrobial thermometer The ultimate solution for hygiene and safety in fever management. Microlife presents the innovative antimicrobial thermometer the world s first thermometer with implementation of copper alloy. Through it s patented technological application, it aims to create safe thermometry conditions, not only to families but to the entire healthcare chain (doctorsnursespatients). The antimicrobial copper which is applied on the thermometer s tip and battery cover kills a wide range of pathogenic microbes, drastically reducing microbial flora on the coated parts and causes significant pathogenic microbes reduction to the rest of the body of the thermometer. The result of it s continuous and ongoing antimicrobial action is the decrease of pathogenic microbes spreading, thus providing high safety and protection to the user. Greek national patent No: ( )/ ; International Patent Application No: WO/2013/064847; European Patent Application No / Human Fever Management

39 Gold Temp TM Measuring Tip GOLD TEMP TM 1 no nickel in direct contact with the skin. The anallergic 1 way to measure. The Microlife GoldTemp TM thermometers are goldplated and are ideal for people who are sensitive to nickel, a metal used on the probes of standard thermometers. The patented (EM Design ) gold tip is the first of its kind and offers a perfect solution for people who are allergic to nickel. It is suitable for adults, children and babies. Illuminated Probe and «clean me» Technology The new transparent probe with LED light function helps to find the position of the ear in the dark. The «clean me» function reminds you to clean the probe before turningoff the thermometer: «clean me» is displayed on the LCD and the illuminated probe flashes for 3 seconds. Tracking Light Technology The blue tracking light of the Non Contact thermometer indicates the correct measurement area and also the distance in the dark. Mercury Free Thermometers Mercury in thermometers has been officially forbidden by the European Union in April 2009 due to the fact that it is a highly toxic heavy metal. Microlife has always been producing mercury free thermometers due to its awareness of the human wellbeing and protection of the environment. Biocompatibility Phthalate and BPA free material B i o c o m p a t l e i b Microlife thermometers have been tested for biocompatibility in order to guarantee the absolute harmless application of the thermometers for the user. All the materials of applied parts in Microlife thermometers are biocompatible in compliance with ISO Fever in Europe In cooperation with an Austrian Hospital several studies have been conducted proving the accuracy and reliability of our infrared thermometers. Human Fever Management 39

40 Display options 4 Single boxes in display 4 Single boxes in display available for: NC 150, IR 150 available for: NC 100, IR 120 IFR 100, IR 100 FR Thermometers in display: 4 colours; 5 thermometers per colour 12 Single boxes in display available for: MT 50 MT 100 available for: MT 710, MT 700 MT 550, MT 510, MT 500 MT 410, MT 200 MT 300, MT 100, MT Human Fever Management

41 Phthalate and BPA free material Asthma Management Peak Flow Meter Asthma Monitor Classic Suitable for children & adults High accuracy Software included PF 100 Peak expiratory flow PEF & FEV 1 measurement 240 Data memory Rotating vane wheel method Traffic light indicator with Analyser Software Easy installation Simple operation Clear data overview Traffic light system for selfassessment Specified Use: Asthmatics who have to check their peak flow regularly and would like to solve the tiresome task of keeping a regular asthma diary. Results are digitally measured and electronically interpreted. Nebulisers Professional Compressor Nebuliser Professional 2 in 1 Nasal washer for the treatment of upper airways Breathenhanced nebuliser for lower airways Low noise level Asthma NEB 10A Large accessory compartment Continuous operation Easy to transport Adapter for nasal wash and aerosol therapy 3 replacement air filters Mouthpiece with expiratory valve Noninvasive nasal dispenser Adult & child face masks B i o c o m p a t l e i b Human Fever Management 41

42 Phthalate and BPA free material Phthalate and BPA free material Compressor Nebuliser Fast Fast & efficient Suitable for intensive use Adjusts to breathing characteristics NEB 50A Extremely fine nebulisation Nebuliser holder Transport handle 30 min. ON / 30 min. OFF Mouthpiece with expiratory valve Adult & child face masks 3 replacement air filters Carrying bag B i o c o m p a t l e i b Compressor Nebuliser Advanced 3 different nebulisation rates Suitable for intensive use Adjusts to breathing characteristics NEB 50B Individual nebulisation Breathenhanced nebuliser Nebuliser holder Transport handle Mouthpiece with expiratory valve Adult & child face masks 30 min. ON / 30 min. OFF Carrying bag B i o c o m p a t l e i b Compact Plus & Basic Compact & convenient Medically highly effective For the whole family Compressor Nebuliser NEB 100A Easy to use and clean Cable storage Nebuliser holder Mouthpiece 3 replacement air filters Adult & child face masks 30 min. ON / 30 min. OFF Carrying bag (not supplied with Compact Basic) Phthalate and BPA free material B i o c o m p a t l e i b Available in two versions: 1. NEB 100A Compact Plus (bicolor, with carrying bag) 2. NEB 100B Compact Basic (all white, without carrying bag) 42 Asthma Management

43 Phthalate and BPA free material Phthalate and BPA free material B i o c o m p a t l e i b NEB 1000 Mini Portable Compressor Nebuliser Fast and efficient treatment Small and lightweight Low noise operation One button, Easy to use Compact desgin Nebuliser holder Mouthpiece with expiratory valve Nose piece 3 replacement air filters Adult & child face masks 30 min. ON / 30 min. OFF Carrying bag Active Compressor Nebuliser Compact & convenient Fast and efficient treatment For the whole family NEB 200 Easy to use and clean Nebuliser holder Adult & child face masks Mouth and nose piece 5 replacement air filters 30 min. ON / 30 min. OFF Carrying bag Vital Compressor Nebuliser Asthma Compact and convenient Medically highly effective For the whole family NEB 500 Efficient nebulisation system Nebuliser holder Transport handle Cable storage Adult & child face masks Mouth and nose piece 5 replacement air filters Continuous operation B i o c o m p a t l e i b Asthma Management 43

44 Mesh Nebuliser Pocket Mesh Portable, pocket size design One button User friendly interface Ultra light and silent Phthalate and BPA free material B i o c o m p a t l e i b NEB 800 Leading «Vibrating Mesh Technology» (VMT) Ultra light Automatic switchoff Very easy to use For the whole family Silent with low power consumption Pulse Oximeter Pulse Oximeter Fingertip OXY 300 Determining oxygen saturation (SpO 2 ) and heart rate (pulse) Comfortable measurement Lightweight and portable Phthalate and BPA free material B i o c o m p a t l e i b Oxygen level Pulse rate Specified Use: For respiratory disease, altitude activities, and sports. Simple to operate Dual color OLED display 6 Display modes 10 Brightness levels Low battery indication Automatic switchoff With carrying strap and carrying bag 44 Asthma Management

45 Comparison Technical specification Nebulisation rate (NaCl) Particle size * (NaCl) Nebuliser capacity Maximum pressure Compressor air flow Operating air flow Sound noise level Operating cycles Weight Size Warranty Nebuliser Nasal washer Nebuliser Nasal washer NEB 100A NEB 100B 0.35 ml/min 2.61 μm 75% < 5 μm 12 ml 1.85 bar 12 l/min. 5.0 l/min. at 70 kpa 56 dba 30 min ON/30 min. OFF 1200 g 140 x 150 x 120 mm 3 years NEB ml/min 3.16 µm 71.2% < 5 μm 8 ml 2.2 bar 15 l/min l/min. at 70 kpa 52 dba 30 min ON/30 min. OFF 1300 g 92 x 160 x 140 mm 5 years NEB 50A 0.50 ml/min μm 75% < 5 μm 16 ml 1.95 bar 13 l/min. 5.2 l/min. at 70 kpa 53 dba 30 min ON/30 min. OFF 1300 g 209 x 140 x 124 mm 3 years NEB 50B 0.19 / 0.38 / 0.55 ml/min / 8.17 / μm 12 ml 1.95 bar 13 l/min. 5.2 l/min. at 70 kpa 53 dba 30 min ON/30 min. OFF 1300 g 209 x 140 x 124 mm 3 years Technical specification NEB 10A NEB 500 NEB 1000 NEB 800 Asthma Nebulisation rate (NaCl) Particle size (NaCl) Nebuliser capacity Maximum pressure Compressor air flow Operating air flow Sound noise level Operating cycles Weight Size Warranty Nebuliser Nasal washer Nebuliser Nasal washer 0.55 ml/min 5.58 ml/min μm 75% < 5 μm * 34.9 μm 94% >10 μm * 12 ml 2.5 bar 15 l/min. 5.5 l/min. at 70 kpa 52 dba Continuous use 1600 g 280 x 270 x 107 mm 5 years 0.3 ml/min μm (MMAD) 13 ml 2.89 bar 5 ~ 8 l/min. N/A 53 dba Continuous use 1400 g 200 x 158 x 93 mm 3 years 0.45 ml/min μm 75% < 5 μm 16 ml 1.65 bar 12 l/min. 5.0 l/min. at 70 kpa 51 dba 30 min ON/30 min. OFF 400 g 98 x 131 x 51.5 mm 3 years 0.2 ml/min 5 μm (MMAD) 8 ml N/A N/A N/A < 30 dba Continuous use 130 g 121 x 44 x 59 mm 2 years Microlife aerosol therapy products are designed to ensure high therapeutic efficacy and to increase patient compliance to the therapy recommended by their physicians. * Using Cascade Impactor Asthma Management 45

46 Asthma technologies Professional Nebuliser System High performance system for the upper and medium/lower respiratory tract Suitable for continuous use and every day treatment Nasal washer Use the nasal washer for a fast & efficient treatment of the upper respiratory tract. For allergic and nonallergic rhinitis, rhinosinusitis, nasal polyps, tubotympanitis, etc. Aerosol therapy Choose between the breathenhanced valve system or the short therapy option to treat the medium & lower airways. For chronic disorders such as asthma, cystic fibrosis, chronic bronchitis, etc. Innovative Nebulisation System Nebulises any medication effectively Choose from 3 different nebulisation rates Enables the correct quantity of medication to be featured to the respiratory tract 1 Inhalation Exhalation 2 Two treatment options: Short therapeutic session without the breathenhanced valve system Advanced treatment with the breathenhanced valve system which adjusts to the breathing characteristics The valve controls the flow of medication during inhalation 1, thus reducing medication loss during exhalation 2. Innovative Nebulisation System Nebulises any medication effectively Enables the correct quantity of medication to be featured to the respiratory tract Phthalate and BPA free material B i o c o m p a t l e i b Biocompatible This compressor nebuliser was developed using biocompatible material only. Contains no phthalate nor bisphenol A This device is safe to be used with all common inhalation solutions. Suitable for the inhalation of corticosteroids 46 Asthma Management

47 Flexible Heating FH 80 Standard heating pad 4 Temperature levels Fast warmup Quick & comfortable FH 80 4 Temperature levels Even heat distribution Ultrathin heating filament 90 Minutes auto shutoff Fast warmup Machine washable cotton cover: 40 C Low EMF* High safety level Traditional heating pad FH 100 FH Temperature levels Fast warmup Auto shutoff 4 Temperature levels Even heat distribution Ultrathin heating filament 90 Minutes auto shutoff Fast warmup Machine washable cotton cover: 40 C Low EMF* High safety level Comfort heating pad FH 200 / FH 200C Optional: Cushion insert for back support and extra comfort FH 200 FH 200C 6 Temperature settings Fast warmup Auto shutoff 6 Temperature levels Even heat distribution Ultrathin heating filament 90 Minutes auto shutoff Fast warmup Machine washable cotton cover: 40 C Low EMF* High safety level Flexible Heating Flexible Heating 47

48 Ergonomic heating pad for back & neck FH Temperature settings Auto shutoff Ergonomic shape for back & neck FH Temperature levels Even heat distribution Ultrathin heating filament 90 Minutes auto shutoff Fast warmup Machine washable cotton cover: 40 C Low EMF* High safety level Ergonomic heating pad for lower back & waist FH 310 FH 310 Auto shutoff 3 Temperature settings Ergonomic shape for lower back & waist 3 Temperature levels Even heat distribution Ultrathin heating filament 90 Minutes auto shutoff Fast warmup Machine washable cotton cover: 40 C Low EMF* High safety level Ergonomic heating pad for neck & shoulder FH 320 FH 320 Auto shutoff Machine washable cover Ergonomic shape for neck & shoulder 4 Temperature levels Even heat distribution Ultrathin heating filament 90 Minutes auto shutoff Fast warmup Machine washable cotton cover: 40 C Low EMF* High safety level * EMF = Electric magnetic field 48 Flexible Heating

49 Underblanket FH 422 FH Temperature settings Auto shutoff Machine washable 3 Temperature levels Even heat distribution Ultrathin heating filament 12 Hours auto shutoff Fast warmup Machine washable: 40 C Low EMF* High safety level 80 x 150 cm Foot Warmer FH 600 FH 600 Auto shutoff Washable Cover 3 Temperature settings 3 Temperature levels Even heat distribution Ultrathin heating filament 90 Minutes auto shutoff Fast warmup Machine washable cover: 40 C High safety level Heat therapy technologies MSS Microlife Safety Standard Latest wiring technology. Microlife heating pads conform to the highest safety requirements. This safety is attributable to the extreme flexibility of the heating wire, the builtin overheating control and the high quality of materials used. Three levels of safety. 1. Short Circuit Safety 2. Overheat Protection via Fusible Layer 3. PTC Temperature Monitoring Even Heat Distribution Feeling warm and comfortable. Microlife heating pads have been designed for use on specific body parts where heat therapy is most effective. The pads offer the largest surface areas of heat yet remain compact for easy application and storage. Microlife heating pads are characterised by an even and fast heat distribution. Microlife technology Conventional technology Flexible Heating Flexible Heating 49

50 Weight Management Easy Weight Scale STEP ON WS 50 For the whole family Easy to use Instant on Weight measurement Large, easy to read display Instant on Slim and compact design Auto shutoff 150 kg capacity 100 g division KG St lb selection Scale size 30 x 30 cm Weight Scale Flat WS 60 For the whole family Slim and modern design Step on STEP ON Weight measurement Large, easy to read display Step on Slim and compact design Auto shutoff 150 kg capacity 100 g division KG St lb selection Scale size 30 x 30 cm Diagnostic Scale Slim TAP ON Bang WS User memory Slim design Measures weight, body fat, body water, muscle mass, bone mass, BMI and BMR Weight measurement Body fat measurement Body water measurement Muscle mass measurement Body mass index measurement Bone mass measurement Basal metabolic rate measurement Large display 180 kg capacity 100 g division KG St lb selection 50 Weight Management

51 Diagnostic Scale STEP ON WS 90 Smart 10 User memory Slim design Measures weight, body fat, body water, muscle mass, bone mass and BMI Weight measurement Body fat measurement Body water measurement Muscle mass measurement Bone mass measurement Body mass index measurement Large display 180 kg capacity 100 g division KG St lb selection WS 100 Simple Body Fat Scale 10 User memory Large display Measures weight, body fat & body water 10 Person memory Large display Weight measurement Body fat measurement Body water measurement Athlete mode with 3 levels of activity 150 kg capacity 100 g division KG St lb selection Body composition Body fat mass The essential fat is necessary for the metabolism and some spare fat, which is theoretically surplus, is necessary for those who carry out physical activities. The normal percentage of fat mass on the body weight is approximately 16 % for men and 27 % for women. Body water The body water % is an important indication of the overall «well being» of a human being as water is the most important component of body weight and represents more than half of the total weight. A body water percentage of 57 % is optimum, a variation of 10 % higher or lower is normal. Bone mass Bone mass increases rapidly in childhood and reaches its maximum between 30 and 40 years. It decreases slightly afterwards with increasing age. Healthy nutrition, regular exercise including some level of muscle building can help to reduce bone degeneration. However, little influence can be taken on bone mass. Average adult bone mass is 15 % for male and 12 % for female. Muscle mass Muscle mass is important in determining a healthy body composition. A person with a higher % of muscle mass finds it easier to move, but needs more energy to do it. Body mass index The body mass index (BMI) is a simple index of weightforheight that is commonly used to classify underweight, overweight and obesity in adults. However, it overestimates fatness in people who are muscular or athletic. Weight Management 51 Weight

52 A partner for people. For life. 3G_Company_Brochure 4216 Europe / MiddleEast / Africa Microlife AG Espenstrasse Widnau / Switzerland Tel. +41 / Fax +41 / admin@microlife.ch Asia Microlife Corporation. 9F, 431, RuiGang Road, NeiHu Taipei, 11492, Taiwan, R.O.C. Tel Fax service@microlife.com.tw North / Central / South America Microlife USA, Inc Gulf to Bay Blvd., 2nd Floor Ste A Clearwater, FL / USA Tel Fax msa@microlifeusa.com

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