NEW. Fully Automated Solution. Metabolic Disorders Diabetes Vitamin Deficiencies Inflammatory Diseases Clinical Chemistry Specific Proteins TDM DOA

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1 NEW FAST & ACCURATE DIAGNOSIS OF: Metabolic Disorders Diabetes Vitamin Deficiencies Inflammatory Diseases Clinical Chemistry Specific Proteins TDM DOA Fully Automated Solution Reliable User-friendly Fast results

2 COMPACT & VERSATILE A FULLY AUTOMATED SOLUTION A fully automated, hihly interated compact analyser. Specially desined for small to mid-sized laboratories, doctor offices, specific hospital settins, (rural) labs. Easy to operate menu for fast startup and minimum down time. Disposable reaction cells. Low water consumption. Minimum maintenance required. Very cost effective and precise. 2 years warranty. Fully developed and made in Italy.

3 hs-crp HbA1c Microalbumin & Glucose Clinical Chemistry Specific Proteins Vitamin D Cobalamin (Vit.B12) * Folic Acid (Vit.B9) * TDM * DOA * * Comin soon ALL IN ONE OPERATOR CONSOLE H Hemo One Instrument Unit Graphic and friendly interface assists the operator and simplifies the daily routine work The Hemo One software is modular and expandable for future parameters Simple to operate, minimum trainin requered Remote maintanance possible on demand * Based on MS Windows 10 operatin system HEMO ONE

4 SMALL FOOTPRINT & FLEXIBILITY IS THE ANSWER RELIABLE, FAST & SIMPLE FULLY AUTOMATED SOLUTION Throuhput Pretreatment Number of arms Number of reaents positions Number of samples / calibrators / controls Vials sizes Diluter Reaent volume Sample volume Dosin resolution Typical readin volume Calibration Calibration curves Automatic dilution Incubation & Readin cuvettes Up to 120 tests/hr mono-reaent Up to 60 tests/hr bi-reaent On board, automatic pretreatment of whole blood with HbA1c lysin reaent 1 liquid dispenser arm with capacitive liquid level detector and obstacle sensor mm Ø with 75/85 mm heiht, and 3 ml sample cups 1 hih-precision micro-meterin pump for dosin reaents and samples μl μl 1 microliter 200/250 μl On-line Calibration, QC and patient results archive Linear reression, piece-wise, cubic spline, polynomial (selected automatically by assay application) Automatic / on request 72 disposable on-board

5 TECHNICAL SPECIFICATIONS SIMPLE TO OPERATE - LOW MAINTENANCE Reaction temperature Wavelenths Liht source Photometric linearity Water consumption Reaent cooler Barcode Interface to LIS host STAT function Operator Console +37 C ± 0.1 C 8 from 340 to 700 nm Lon life haloen lamp (2000 hours life) OD Low water consumption due to use of disposable cuvettes Up to 14 C below ambient temperature (optional) Yes (fully interated for sample and reaents) Bi-directional connection, Ethernet Selectable on all sample positions External, All-in-One computer with Touch Screen Operational system MS Windows 10 GUI Printer Workin Environment Real-time electronics Power manaement Power supply Dimensions Weiht Easy to use and wizard-style user interface USB connection Temperature C Relative humidity % Modular, SMD Automatic start-up and shut-down Vac, Hz 45(W) x 46(D) x 50(H) cm 25 k HEMO ONE

6 TESTS MENU HEMO ONE TESTS HbA1c MICROALBUMIN GLUCOSE hs-crp VITAMIN D VITAMIN B12* VITAMIN B9* TDM* DOA* * Comin soon CLINICAL CHEMISTRY REAGENT KITS ALBUMIN BCG CK MB SL IRON ALT / GPT SL CK NAC SL MAGNESIUM ALP (DEA) SL CREATININE PHOSPHOROUS UV AMYLASE GAMMA GT SL TOTAL PROTEIN AST / GOT SL GLUCOSE PAP TRIGLYCERIDES BILIRUBIN DIRECT HDL CHOLESTEROL UREA UV SL BILIRUBIN TOTAL LDL CHOLESTEROL URIC ACID CALCIUM ARSENAZO LDH-P SL CHOLINESTERASE CHOLESTEROL PAP TURBIDIMETRY REAGENT KITS ALBUMIN CERULOPLASMIN IM ALFA-1 - ACID GLYCOPROTEIN COMPLEMENT C3 KAPPA LIGHT CHAIN ALFA-1 - ANTITRYPSIN COMPLEMENT C4 LAMBDA LIGHT CHAIN ALFA-2 MACROGLOBULIN CRP LIPOPROTEIN (A) ANTITHROMBIN III FIBRINOGEN MICROALBUMIN APOLIPO PROTEIN A1 HAPTOGLOBIN PREALBUMIN APOLIPO PROTEIN B IA TRANSFERRIN C1 ESTERASE INHIBITOR IG CE-IVD marked reaents panel: Ready to use Stable formulations based on IFCC & DGKC recommendations for whole blood, serum, plasma and urine samples LATEX REAGENT KITS ANTI-STREPTOLYSIN (O) BETA 2 - MICROGLOBULIN FERRITIN RHEUMATOID FACTOR GENERIC CALIBRATORS & CONTROLS MULTICALIBRATOR NORMAL CONTROL SERUM PATHOLOGICAL CONTROL SERUM

7 Positive identification of reaents ives the end user the assurance to work without compromises on quality. Twenty-eiht parameters for enzymes and substrates, with application on serum, plasma and urine, based on the most advanced research in clinical chemistry followin international recommendations (IFCC). Twenty-eiht parameters for specific protein, with application on serum, plasma and urine, standardized with 5-point calibration curve. HEMO ONE

8 R&D and Production: I.S.E. S.r.l. Via Luii Einaudi, 7 Guidonia Montecelio Rome, Italy Tel: Fax: Leal site: I.S.E. S.r.l. Via delle Driadi, Rome, Italy I.S.E. is a dynamic company specialized in development and manufacturin of Laboratory Analysers and associated Reaents. I.S.E. is an ISO 9001:2008 and ISO 13485:2012 certified company and all our products are CE marked. Several other certifications available. I.S.E. have thousands of solutions installed worldwide. I.S.E. provides to our customers hih end, hih quality and reliable solutions of Analysers and Reaents. Ease of use, combined with minimal operatin requirements makes ISE systems the best choice for any laboratory. Customer Care Center: info@lootech-ise.com Tel: Fax: Sales and Marketin office: sales@lootech-ise.com Tel: Fax: We are dedicated to customer satisfaction and will do the utmost to respond quickly to your needs. Technical service: service@lootech-ise.com Tel: Fax: Order handlin and loistics: order@lootech-ise.com Tel: Fax: Hemo One Ref. BRO1010 V2.1 I.S.E S.r.l. All rihts reserved. All trademarks are property of their respective owners. Specifications are subject to chane without notice.