DAFTAR PUSTAKA. 2. Undurti N Das. Insulin in Sepsis and Septic Shock. JAPI. 2003; 51:

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1 33 DAFTAR PUSTAKA 1. Dan L Longo, Dennis L Kasper, J Larry Jameson, Anthony S Fauci, Stephen L Hauser, Joseph Loscalzo. Harrison s Principles of internal medicine. USA: The McGraw-Hill Companies; Undurti N Das. in Sepsis and Septic Shock. JAPI. 2003; 51: Van Den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schietz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouikkon R. Intensive Therapy in Critically Ill Patients. N Engl J Med. 2001; 345: Jonathan Cohen. The immunopathogenesis of sepsis. Nature [Internet] [cited 2012 October 8]; 420: Available from: 5. F Wong, M Bernardi, R Balk, B Christman, R Moreau, G Garcia-Tsao, et al. Sepsis in cirrhosis: report on the 7 th meeting of the International Ascites Club. Gut [Internet].2005 [cited 2012 December 24]; 54: Available from: gut.bml.com. 6. Arthur C Guyton, John E Hall. Buku ajar fisiologi kedokteran. Jakarta: EGC; Anselm O Agwunobi, Claire Reid, Paula Maycock, Roderick A Little, Gordon L Carlson. Resistence and Substrate Utilization in Human Endotoxemia. JCE & M. 2000; 85: Armella Mathonet, Alain Cariou. Glycemic Control in Sepsis. Adv Sepsis. 2007; 6(1):16-18.

2 34 9. Paul E Marik, Murugen Raghavan. Stress-hyperglycemia, insulin and immunomodulation in sepsis. Intensive Care Med. 2004; 30: Alain Cariou, Christophe Vinsonneau, Jean-Francois Dhainaut. Adjunctive therapies in sepsis: An evidence-based review. Crit Care Med. 2004;32(11):S562-S Eric A J Hoste, Norbert H Lameire, Raymond C Vanholder, Dominique D Benoit, Johan M A Decruyenaere, Francis A Colardyn. Acete Renal Failure in Patients with Sepsis in a Surgical ICU: Predictive Factor, Incidence, Comorbidity, and Outcome. J Am Soc Nephrol.2003; 14: Greg S Martin, Stephanie Eaton, Meredith Mealer, Marc Moss. Extravascular lung water in patients with severe sepsis: a prospective cohort study. Critical Care [Internet] [cited 2012 December 24]; 9(2): R74-R82. Available from: Andreas Hillenbrand, Manfred Weiss, Uwe Knippschild, Anna Maria Wolf, Markus Huber-Lang. Sepsis-induced adipokine change with regard to insulin resistance. International Journal of Inflamation. 2012: Can Ince. The microcirculation is the motor of sepsis. Critical Care [Internet] [cited 2012 December 24]; 9(suppl 4): S13-S19. Available from: Soren Kaeseler Andersen, Jakob Gjedsted, Christian Christiansen, Else Tonnesen. The roles of insulin and hyperglycemia in sepsis pathogenesis. Journal of Leukocyte Biology. 2004; 75: Abdulaziz S Aldawood, Hani M Tamim, Mohammed A Alsultan, Asgar H Rishu, Yaseen M Arabi. Intensive insulin therapy versus conventional insulin

3 35 therapy for critically ill trauma patients admitted to ICU. M E J Anesth [Internet] [cited 2013 January 24]; 20(5): Available from: Abbas E Kitabchi, Guillermo E Umpierrez, Mary Beth Murphy, Eugene J Barrett, Robert A Kreisberg, Johan I Malone, et al. Management of hyperglycaemic crises in patients with diabetes. Diabetes Care. 2001; 24: John Koskinas, Ilias P Gomatos, Dina G Tiniakos, Nikolas Memos, Maria Boutsikou, Aspasia Garatzioti, Athanasios Archimandritis, et al. Liver histology in ICU patients dying from sepsis: A clinic-pathological study. World J Gastroenterol [Internet] [cited 2013 January 22]; 14(9): Available from: Herbert Spapen. Liver perfusion in sepsis, septic shock, and multiorgan failure. The Anatomical Record [Internet] [cited 2013 January 22]; 291: Available from: Wiley Interscience. 20. Robert KM, Daryl KG, Victor WR. Biokimia harper. Jakarta: EGC; Sacha Zeerleder, Erik Hack, Walter A Wuillemin. Disseminated Intravascular Coagulation in Sepsis. CHEST [Internet] [cited 2013 January 3]; 128: Available from: Frank M Brunkhorst, Christoph Engel, Frank Bloos, et al. Intensive Therapy and Pentastarch Resuscitation in Severe Sepsis. N Engl J Med. 2008; 358: Sidharta Das, Bijay Misra. Resistance as Prognostic Indicator in Multi Organ Dysfunction Syndrome. Medicine Update. 2011:

4 Ricardo Gracia Branco, Robert Charles Tasker, Pedro Celiny Ramos Gracia, et al. Glycemic control and insulin therapy in sepsis and critical illness. Jurnal de Pediatria. 2007; 83(Suppl 5): S128-S Zdenek Rusavy, Vladimir Sramek, Silvie Lacigova, et al. Influence of insulin on glucose metabolisme and energy expenditure in septic patients. Critical Care. 2004; 8: R213-R Tri Murti Andayani, Mohamed Izham Mihemed Ibrahim, Ahmad H Asdie. Comparison of the glycemyc control of insulin and triple oral therapy in type 2 diabetes mellitus. Journal of Diabetes and Endocrinology. 2010: 1 (2):

5 37 Lampiran Descriptive Statistics N Minimum Maximum Mean Std. Deviation Jenis Kelamin Pasien Usia Pasien GDS Sebelum Pemberian GDS Sesudah Pemberian Valid N (listwise) 22 Case Processing Summary Cases Valid Missing Total N Percent N Percent N Percent GDS Sebelum Pemberian % 0.0% % GDS Sesudah Pemberian % 0.0% %

6 38 Jenis Kelamin Pasien Cumulative Frequency Percent Valid Percent Percent Valid Laki-laki Perempuan Total Descriptives Statistic Std. Error GDS Sebelum Pemberian Mean % Confidence Interval for Mean Lower Bound Upper Bound % Trimmed Mean Median Variance Std. Deviation Minimum 100 Maximum 585 Range 485 Interquartile Range 215 Skewness Kurtosis

7 39 GDS Sesudah Pemberian Mean % Confidence Interval for Mean Lower Bound Upper Bound % Trimmed Mean Median Variance Std. Deviation Minimum 62 Maximum 401 Range 339 Interquartile Range 107 Skewness Kurtosis Tests of Normality Kolmogorov-Smirnov a Shapiro-Wilk Statistic df Sig. Statistic df Sig. GDS Sebelum Pemberian * GDS Sesudah Pemberian * a. Lilliefors Significance Correction *. This is a lower bound of the true significance.

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9 41 Paired Samples Statistics Mean N Std. Deviation Std. Error Mean Pair 1 GDS Sebelum Pemberian GDS Sesudah Pemberian

10 42 Paired Samples Correlations N Correlation Sig. Pair 1 GDS Sebelum Pemberian & GDS Sesudah Pemberian Paired Samples Test Paired Differences 95% Confidence Interval Std. Std. Error of the Difference Sig. (2- Mean Deviation Mean Lower Upper t df tailed) Pair 1 GDS Sebelum Pemberian - GDS Sesudah Pemberian

11 43 IDENTITAS Nama : Desriyan Purnama Putra NIM : G2A Tempat/Tanggal Lahir : Rimbo Bujang/ 23 Desember 1991 Jenis Kelamin : Laki-laki Alamat : Jalan Bukit Kelapa Sawit VII AD 27 Tembalang No Telepon : - No HP : desriyan@gmail.com Riwayat Pendidikan Formal 1. SD : SD 81/VIII Lulus Tahun: SMP : SMP N 3 Tebo Lulus Tahun: SMA : SMA N 2 Tebo Lulus Tahun: FK Undip : Masuk Tahun: 2009 Keanggotaan Organisasi Anggota Maladica ( Mahasiswa Pecianta Alam Medica) FK Undip sejak 2010 Pengalaman Penelitian Pengalaman Publikasi Tulisan Ilmiah Pengalaman Presentasi Karya Tulis Ilmiah Pengalaman Mengikutai Lomba Karya Ilmiah

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