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1 DAFTAR PUSTAKA 1. Yao YM, Luan YY, Zhang QH, Zhi-Yong S. Pathophysiological aspects of sepsis: an overview. Methods in Molecular Biology 2014;1237: Angus DC, Van der Poll T. Severe sepsis and septic shock. NEJM 2013;369: Alberti C, Brun-Buisson C, Chevret S, Antonelli M, Goodman SV, et al. Systemic inflammatory response and progression to severe sepsis in critically ill infected patients. Critical Care Med 2005;171: Keegan J, Wira CR. Early identification and management of patients with severe sepsis and septic shock in the emergency department. Emergency Medicine Clinics Of North America 2014;32(4): Hall MJ, Williams SN, DeFrances CJ, Golosinskiy A. Inpatient care for septicemia or sepsis: a challenge for patients and hospital. NCHS Data Brief 2011; Vincent JL, Sakr YMB, Sprung CL, Ranieri VM. Sepsis in European intensive care units: results of the SOAP study. Critical Care Med 2006;34(2): Vincent JL, Rello J, Marshall J, et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA 2009;302: Póvoa P, Salluh JI. Biomarker-guided antibiotic therapy in adult critically ill patients: a critical review. Ann Intensive Care 2012;2(1): Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock. Critical Care Med 2012:

2 Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, et al. Harrison s Manual of Medicine 16 th Edition. USA: McGraw-Hill Companies, 2005: Artero A, Zaragoza R, Nogueira JM. Epidemiology of severe sepsis and septic shock. Spain: Critical Care and Emergency Medicine, 2012: McPhee SJ, Hammer GD. Pathophysiology of Disease: An Introduction to Clinical Medicine 6 th Edition. USA: McGraw-Hill Companies, 2010: Moss M. Epidemiology of sepsis: race, sex, and chronic alcohol abuse. Oxford Journals: Clinical Infectious Disease 2005;41(7): The EPISEPSIS Group. EPISEPSIS: A reappraisal of the epidemiology and outcome of severe sepsis in French intensive care units. Intensive Care Med 2004;30: Mayr FB, Yende S, Angus DC. Epidemiology of severe sepsis. Virulence: 2014;5(1): Nachtigall I, Tafelski S, Rothbart A, Kaufner L, Schmidt M, et al. Genderrelated outcome difference is related to course of sepsis on mixed ICUs: a prospective, observational clinical study. Critical Care Medicine 2011;15(3):R Pietropaoli AP, Glance LG, Oakes D, Fisher SG. Gender differences in mortality in patients with severe sepsis or septic shock. Gend Med 2010;7(5):

3 Dombrovskiy VY, Martin AA, Sunderram J, Paz HL. Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to Critical Care Med 2007;35: Martin GS, Mannino DM, Moss M. The effect of age on the development and outcome of adult sepsis. Critical Care Med 2006;34: Angus DC, Linde-Zwirble WT. Severe sepsis epidemiology: sampling, selection, and society. Critical Care Med 2004;8(4): Carbajal-Guerrero J, Cayuela-Dominguez A, Fernandez-Garcia E, Aldabo- Pallas T, Marquez-Vacaro JA, et al. Epidemiology and long-term outcome of sepsis in elderly patients. Med Intensiva 2014;38(1): Lemay AC, Anzueto A, Restrepo MI, Mortensen EM. Predictors of long-term mortality after severe sepsis in the elderly. Am J Med Sci 2013;347(4): Quenot JP, Binguet C, Kara F, Martinet O, Ganster F, et al. The epidemiology of septic shock in French intensive care units: the prospective multicenter cohort EPISS. Critical Care Med 2013;17(2):R Phua J,Ngerng WJ, See KC, Tay CK, Kiong T, et al. Characteristics and outcomes of culture-negative versus culture-positive severe sepsis. Critical Care Med 2013;17(5):R Vincent JL, Moreno R. Clinical review: scoring system in the critically ill. Critical Care Med 2010;14: Goldis A, Ratiu I. Acute biliary pancreatitis: from diagnosis to treatment. Timisoara Medical Journal 2007;4.

4 Mayr FB, Yende S, Angus DC. Epidemiology of severe sepsis. Virulence 2014;5(1): Yang Y, Yang KS, Hsann YM, Lim V, Ong BC. The effect of comorbidity and age on hospital mortality and length of stay in patients with sepsis. Journal of Critical Care 2010;25(3): Engel C, Brunkhorst FM, Bone HG, Brunkhorst R, Gerlach H, et al. Epidemiology of sepsis in Germany: results from a national prospective multicenter study. Intensive Care Med 2007;33: Sudoyo AW, Setiyohadi B, Alwi I, Simadibrata M, Setiati S. Buku Ajar Ilmu Penyakit Dalam Jilid 3 Edisi V. Jakarta: Interna Publishing, 2009: Andrew TL, Brian PC, Mitchell ML. Reducing mortality in severe sepsis and septic shock. Semin Respir Crit Care Med 2011;32(2): Keputusan Menteri Kesehatan Republik Indonesia Nomor 1778 Tahun Padkin A, Goldfrad C, Brady AR, Young D, Black N, Rowan K. Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland. Crit Care Med 2003;31: Finfer S, Bellomo R, Lipman J, French C, Dobb G, Myburgh J. Adult population incidence of severe sepsis in Australian and New Zealand intensive care units. Intensive Care Med 2004;30: Blanco J, Muriel-Bombin A, Sagredo V, Taboada F, Gandia F, et al. Incidence, organ dysfunction and mortality in severe sepsis: a Spanish multicentre study. Critical Care Med 2008(12):R158.

5 Kaukonen KM, Bailey M, Suzuki S, Pilcher D, Bellomo R. Mortality Related to Severe Sepsis and Septic Shock Among Critically Ill Patients in Australia and New Zealand, JAMA 2014;311(13): Martin GS, Mannino DM, Moss M. The Effect of Age on the Development and Outcome of Adult Sepsis. Critical Care Med 2006;34(1): Higgins C. Laboratory Diagnosis of Sepsis: blood culture and beyond. 2010(5): van Gestel A, Bakker J, Veraart CPWM, van Hout BA. Prevalence and incidence of severe sepsis in Dutch intensive care units. Critical Care Med 2004(8):R Annane D, Aegerter P, Jars-Guincestre MC, Guidet B. Current epidemiology of septic shock. Critical Care Med 2002;168:

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8 68 Lampiran 3. Biodata Mahasiswa Identitas Nama : Victoria Natasha Suwondo NIM : Tempat/tanggal lahir : Semarang, 06 Juli 1994 Jenis kelamin Alamat : Perempuan : Jl.Semarang Indah EI/102, Semarang Nomor Telepon : (024) Nomor HP : victorians27@live.com Riwayat Pendidikan Formal 1. SD : SD Kristen 3 YSKI Lulus tahun: SMP : SMP PL Domenico Savio Lulus tahun: SMA : SMA Karangturi Lulus tahun: FK UNDIP : Masuk tahun : 2011

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