MELISSA A.H. WITMAN, PH.D.

Transcription

1 MELISSA A.H. WITMAN, PH.D. University of Delaware STAR Campus Newark DE Assistant Professor Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE EDUCATION Postdoctoral Research Fellow, SLC VA Medical Center, Internal Medicine/Geriatrics - Salt Lake City, UT October 2011-December 2014 PhD, University of Utah, Exercise and Sport Science, Exercise Physiology Salt Lake City, UT August September 2011 MS, University of New Hampshire, Kinesiology Durham, NH August 2003 August 2005 BS, St. Lawrence University, Major in Biology, Minor in Sports Studies and Exercise Science Canton, NY August 1999-May 2003 ACADEMIC APPOINTMENTS Assistant Professor Department of Kinesiology and Applied Physiology, University of Delaware Newark, DE - August 2015-present Research Associate Internal Medicine/Geriatrics, University of Utah Salt Lake City, UT - January 2015-August 2015 Postdoctoral Research Fellow - SLC VA Medical Center, Internal Medicine/Geriatrics Salt Lake City, UT - October 2011-December 2014 Graduate Research Assistant University of Utah, Department of Exercise and Sport Sciences Salt Lake City, UT May 2008-September 2011 Graduate Research Assistant University of Utah, The Orthopedic Specialty Hospital Murray, UT August 2007-May 2008 Instructor & Academic Advisor University of New Hampshire, Kinesiology Exercise Science Durham, NH August 2005-May 2007 Graduate Research Assistant University of New Hampshire, Kinesiology Exercise Science Durham, NH August 2003-August 2005

2 PEER-REVIEWED PUBLICATIONS (note name change from Hayman to Witman) 1. Edwards, DG, Gauthier, AL, Hayman, MA, Lang, JT, and Kenefick, RW. Acute Effects of Cold Exposure on Central Aortic Wave Reflection. Journal of Applied Physiology, 100: , Hayman, MA, Wray, DW, and Richardson, RS. Comment on: Commentaries on viewpoint: Pick your Poiseuille: normalizing the shear stimulus in studies of flow-mediated dilation. Journal of Applied Physiology, 2009, 107: McDaniel, J, Fjeldstad, AS, Ives, S, Hayman, M, Kithas, P, and Richardson, RS. Central and peripheral contributors to skeletal muscle hyperemia: The response to passive limb movement. Journal of Applied Physiology. 2010, 108: Hayman, MA, Nativi, J, Stehlik, J, McDaniel, J, Fjeldstad, AS, Ives, SJ, Wray, DW, Bader, F, Gilbert, EM, and Richardson, RS. Understanding Exercise-induced hyperemia: Central and peripheral hemodynamic responses to passive limb movement in heart transplant recipients. Am J Physiol Heart Circ Physiol, 2010, 299: H1653-H McDaniel, J, Hayman, MA, Ives, SJ, Fjeldstad, AS, Trinity, JD, Wray, DW, and Richardson, RS. Attenuated Exercise Hyperemia with Age: The response to passive limb movement. Journal of Physiology, 2010, 588: Wray, DW, Witman, MA, Ives, SJ, McDaniel, J, Fjeldstad, AS, Trinity, JD, Conklin, J, Supiano, MA, and Richardson, RS. Progressive Handgrip Exercise: Evidence of Nitric Oxide-dependent Vasodilation and Blood Flow Regulation in Humans. Am J Physiol Heart Circ Physiol, 2011, 300: H Trinity, J, McDaniel, J, Venturelli, M, Fjeldstad, A, Ives, S, Witman, MA, Barrett-O Keefe, Amann, M, Wray, DW, and Richardson, RS. Central and Hemodynamic Contributions to Movement-induced Hyperemia: Impact of Body Position. Am J Physiol Heart Circ Physiol, 2011, 300: H Fjeldstad, AS, McDaniel, J, Witman, MA, Ives, SJ, Zhao, J, Rose, JW, Hannon, J, Wray, DW, and Richardson, RS. Vascular function and the role of oxidative stress in Multiple Sclerosis. J of Neurology, 2011, 258: Ives, SJ, Andtbacka, RHI, Noyes, RD, Witman, MA, McDaniel, J, Amann, M, Symons, JD, Wray, DW, and R.S. Richardson. Effect of Temperature on Alpha- Adrenergic Responsiveness in Human Arteries Studied In Vitro. Exp Physiol, 2011, 96: Wray, DW, Nishiyama, SK, Harris, RA, Zhao, J, McDaniel, J, Fjeldstad, AS, Witman, MA, Ives, SJ, Barrett- O Keefe, Z, and Richardson, RS. Acute Reversal of Endothelial Dysfunction in the Elderly after Antioxidant Consumption. Hypertension, 2012, 59(4): Witman, MA, Fjeldstad, AS, McDaniel, J, Ives, SJ, Zhao, J, Barrett- O Keefe, Z, Nativi, JN, Stehlik, J, Wray, DW, and Richardson, RS. Vascular Function and the Role of Oxidative Stress in Heart Failure, Heart Transplant, and Beyond. Hypertension, 2012, 60(3):

3 12. Larson, A, Witman, MA, Guo, Y, Ives, S, Richardson, RS, Bruno, RS, Jalili, T, and Symons, JD. Acute, quercetin- induced reductions in blood pressure in hypertensives are not secondary to lower plasma angiotensin converting enzyme activity or endothelin- 1: nitric oxide. Nutrition Research, 2012, 32(8): Witman, MA, McDaniel, J, Fjeldstad, AS, Ives, SJ, Zhao, J, Nativi, JN, Stehlik, JS, Wray, DW, and Richardson, RS. A Differing Role of Oxidative Stress in the Regulation of Central and Peripheral Hemodynamics during Exercise in Heart Failure. Am J Physiol Heart Circ Physiol, 2012, 303(10): H (Featured Article). 14. Barrett- O Keefe, Z, Witman, MA, McDaniel, J, Fjeldstad, AS, Trinity, JD, Ives, SJ, Conklin, JD, Reese, V, Runnels, S, Morgan, DE, Sander, M, Richardson, RS, and Wray, DW. Angiotensin- II potentiates alpha- adrenergic vasoconstriction in the elderly. Clinical Science, 2013, 124(6): Ives, SJ, McDaniel, J, Witman, MA, and Richardson, RS. Passive limb movement: Evidence of mechanoreflex sex specificity. Am J Physiol Heart Circ Physiol, 2013, 304(1): H Wray, DW, Witman, MA, Ives, SJ, McDaniel, J, Trinity, JD, Conklin, JD, Supiano, MA, and Richardson, RS. Does brachial artery FMD provide a bioassay for nitric oxide? Hypertension, 2013, 62(2): Trinity, JD, Wray, DW, Witman, MA, Layec, G, Barrett- O Keefe, Z, Ives, SJ, Conklin, J, Reese, V, and Richardson, RS. The Contribution of Nitric Oxide to Brachial Artery Vasodilation during Progressive Handgrip Exercise in the Elderly. Am J Physiol Regul Integr Comp Physiol, 2013, 305(8): R893- R Ives, SJ, Harris, RA, Witman, MA, Fjeldstad, AS, Garten, RS, McDaniel, J, Wray, DW, and Richardson, RS.Vascular Dysfunction and Chronic Obstructive Pulmonary Disease: The Role of Redox Balance. Hypertension, 2014, 63(3): Amann, M, Venturelli, M, Ives, SJ, Morgan, DE, Gmelch, B, Witman, MA, Groot, HJ, Wray, DW, Stehlik, J., and Richardson, RS. Group III/IV Muscle Afferents Impair Limb Blood Flow in Patients with Chronic Heart Failure. Int J Cardiol. 2014, 174(2): Barrett-O Keefe, Z, Lee, JL, Berbert, A, Witman, MA, Nativi, JN, Stehlik, J, Richardson, RS, and Wray, DW. Hemodynamic Responses to Small Muscle Mass Exercise in Heart Failure Patients with Reduced Ejection Fraction. Am J Physiol Heart Circ Physiol 2014, 307(10):H Witman, MA, Ives, SJ, Trinity, JD, Groot, HJ, Stehik, J, and Richardson, RS. Partitioning the Impact of Central and Peripheral Dysfunction in Heart Failure. Int J Cardiol 2015, 178: Rossman, MJ, Trinity, JD, Garten, RS, Ives, SJ, Conklin, J, Barrett-O Keefe, Z, Witman, MA, Bledsoe, A, Morgan, D, Runnels, S, Reese, V, Zhao, J, Amann, M, Wray, DW, and Richardson, RS. Limb Blood Flow During Exercise in Patients with COPD: The Impact of Antioxidants. Am J Physiol Heart Circ Physiol 2015, 309(5):H

4 23. Witman, MA, Garten, RS, Gifford, JR, Groot, HJ, Trinity, JD, Stehlik, J, Nativi, JN, Selzman, CH, Drakos, SG, and Richardson, RS. Further Peripheral Vascular Dysfunction in Heart Failure Patients with a Continuous-flow Left Ventricular Assist Device: The role of pulsatility. JACC Heart Fail. 2015, 3(9): (Associated Editorial Comment). 24. Ives, SJ, Amann, J, Venturelli, M, Witman, MA, Groot, JH, Wray, DW, Morgan, DE, and Richardson, RS. The Mechanoreflex and Hemodynamic Response to Passive Leg Movement in Heart Failure. MSSE 2015 (In Press). 25. Gifford, JR, Garten, RS, Nelson, AD, Trinity, JD, Layec, G, Witman, MA, Weavil, JC, Mangum, T, Hart, C, Etheredge, C, Jessop, J, Bledsoe, A, Morgan, DE, Wray, DW, and Richardson, RS. Symmorphosis and Skeletal Muscle VO2max: In Vivo and In Vitro Measures Reveal Differing Constraints in the Exercise Trained and Untrained Human. J Physiol (In Press). 26. Rossman, MJ, Groot, HJ, Garten, RS, Witman, MA, and Richardson, RS. Vascular Function Assessed by Passive Leg Movement and Flow-mediated Dilation: Evidence of Construct Validity (In Review). 27. Trinity, JD, Wray, DW, Witman, MA, Layec, G, Barrett-O Keefe, Z, Ives, SJ, Conklin, JD, Reese, V, Zhao, J, and Richardson, RS. Ascorbic Acid Improves Brachial Artery Vasodilation during Progressive Handgrip Exercise in the Elderly through a Nitric Oxide-mediated Mechanism. (In Review). PROFESSIONAL PRESENTATIONS (note name change from Hayman to Witman) 1. Hayman, MA, Roy, MS, Kenefick, RW, and Edwards, DG. The Effect of N-acetylcysteine on Cycling Performance in the Heat. New England Regional Chapter of American College of Sports Medicine Fall Meeting, Providence, RI, November Hayman, MA. Injury Prevention for Marathon Training. Team in Training Desert Mountain States Chapter, Salt Lake City, UT, June Hayman, MA, Nativi, J, Stehlik, J, McDaniel, J, Fjeldstad, AS, Ives, SJ, Wray, DW, and Richardson, RS. Understanding exercise-induced hyperemia: central and peripheral responses to passive limb movement in heart transplant patients. Cardiovascular-Slide Presentation. 57 th American College of Sports Medicine Annual Meeting, Baltimore, MD, June Witman, MA. Cardiovascular Responses to Passive Limb Movement in Heart Failure. Invited Speaker. The Physiology of Exercise in Heart Failure Symposium. 59 th American College of Sports Medicine Annual Meeting, San Francisco, CA, June Witman, MA. Vascular function and the role of oxidative stress in heart failure, heart transplantation, and beyond. Invited Presentation. US Army Research Institute of Environmental Medicine (USARIEM), Natick, MA, April 2013.

5 6. Witman, MA, Wray, DW, and Richardson, RS. Progressive handgrip exercise: a new tool for assessing nitric oxide-dependent vasodilation in health and disease. Invited Speaker. Featured Science Session - Assessing Vascular Function: Past, Current, and Future Promises. 60 th American College of Sport Medicine Annual Meeting, Indianapolis, IN, May Witman, MA, McDaniel, J, Ives, SJ, Nativi, JN, Stehlik, J, and Richardson, RS. Heart Transplant Recipients and NO-mediated Vascular Function: Evidence from Passive Limb Movement. Cardiovascular-Slide Presentation. 61 st American College of Sports Medicine Annual Meeting, Orlando, FL, May Witman, MA. Peripheral Vascular Function: In Heart Failure, Heart Transplantation, and with a Left Ventricular Assist Device. Invited Speaker. University of Utah ESS/UVRL Colloquium Series, Salt Lake City, UT, November Witman, MA. Peripheral Vascular Function: HFrEF vs. HFpEF. Invited Speaker. Symposium The Two Faces of Heart Failure: Exercise Intolerance in HFrEF vs. HFpEF Patients. 62 nd American College of Sports Medicine Annual Meeting, San Diego, CA, May CHAPTERS (note name change from Hayman to Witman) 1. Meyer, NL, and Hayman, MA. Nutrition and Fitness Assessment. Sport Nutrition for Health and Performance. 2 nd Edition. Human Kinetics. Champaign, IL. Chapter 14, pages SELECTED PUBLISHED ABSTRACTS (note name change from Hayman to Witman) 1. Hayman, MA, McDaniel, J, Fjeldstad, AS, Ives, SJ, Askew, EW, Bennet, D, and Richardson, RS. Normalizing flow-mediated dilation for shear rate unveils the vascular effect of a nutritional intervention. MSSE. 41(5):78, May Hayman, MA, Nativi, J, Stehlik, J, McDaniel, J, Fjeldstad, AS, Ives, SJ, Wray, DW, and Richardson, RS. Understanding exercise-induced hyperemia: central and peripheral responses to passive limb movement in heart transplant patients. MSSE. 42(5):53-54, May Witman, MA, Fjeldstad, AS, Ives, SJ, McDaniel, J, Barrett-O Keefe, Z, Nativi, JN, Stehlik, J, Bader, F, Gilbert, EM, Wray, DW, and Richardson, RS. Vascular Function and Oxidative Stress: In Health, Heart Failure, Heart Transplantation, and Beyond. MSSE. 43(5):90, May Witman, MA, McDaniel, J, Ives, SJ, Fjeldstad, AS, Zhao, J, Stehlik, J, Wray, DW, and Richardson, RS. Role of Free Radicals in the Regulation of Systemic Vascular Resistance in Chronic Heart Failure. MSSE. 44(5): 3338, May Witman, MA, Groot, HJ, Gifford, JR, Trinity, JD, Stehlik, J, Drakos, SG, and Richardson, RS. The effects of continuous-flow left ventricular assist devices on peripheral vascular function. FASEB J. 27: , April 2013.

6 6. Witman, MA, Wray, DW, and Richardson, RS. Progressive Handgrip Exercise: A New Tool for Assessing Nitric Oxide-Dependent Vasodilation in Health and Disease. MSSE 45(5): 935, May Witman, MA, McDaniel, J, Ives, SJ, Nativi, JN, Stehlik, J, and Richardson, RS. Heart Transplant Recipients and NO-mediated Vascular Function: Evidence from Passive Limb Movement. MSSE 46(5): 3193, May SERVICE -Exercise and Sport Science/Utah Vascular Research Laboratory Colloquium Series Responsible for recruiting both internal and external guest speakers, organizing, and advertising monthly series, January 2012-present -Graduate Student Advisory Committee (SAC) University of Utah, Retention, Promotion, and Tenure Graduate Student Committee University of Utah, Graduate Students Interested in Exercise Physiology (GSIEP) University of Utah - Student group that organized guest speakers and arranged for conference travel and funding, Student Athletic Advisory Council (SAAC) St. Lawrence University, Invited Manuscript Reviewer: -Ad Hoc Reviewer -Journal of Applied Physiology -Arteriosclerosis, Thrombosis, and Vascular Biology -Heart -Experimental Physiology -European Journal of Applied Physiology -Clinical Cardiology -Drug Design, Development, and Therapy -Anatolian Journal of Cardiology -Junior Reviewer (for Dr. Russell S. Richardson, Dr. D. Walter Wray, and Dr. J. David Symons) -Journal of Applied Physiology -AJP Heart & Circulatory Physiology -Medicine and Science in Sports and Exercise Grant Reviewer: -West Virginia Clinical and Translational Science Institute Clinical and Translational Pilot Grants Program. Expert Peer Reviewer (ad hoc), November GRANTS & SUPPORT VA R&D Career Development Program (CDA-1) (Funded) 01/01/ /31/ Advanced Associated Health Research Fellowship in Geriatrics - $133,567 + fringe benefits

7 HONORS & AWARDS - Utah Postdoctoral Association Best Poster Award, University of Utah Postdoctoral Fellow Travel Award, University of Utah 2012 and Outstanding Exercise Physiology Graduate Student Award, University of Utah ACSM Non-invasive Neuromuscular System Interest Group Most Significant Student Abstract Award Associated Students of the University of Utah (ASUU) Travel Award, University of Utah Graduate Student Travel Assistance Award, University of Utah Basil J.F. Mott Outstanding Graduate Student Award, University of New Hampshire NCAA All-Academic Teams Cross Country Running & Nordic Skiing, St. Lawrence University PROFESSIONAL MEMBERSHIPS & CERTIFICATIONS - Mid-Atlantic Chapter of the American College of Sports Medicine (MARCACSM) (2015-present) - American Physiological Society (APS) (2012-present) - American College of Sports Medicine (ACSM) (2005-present) - New England Chapter of the American College of Sports Medicine (NEACSM) ( ) - American Heart Association ACLS Certification (2012-present) - American Heart Association BLS Certification (2010-present) - American Sports Education Program (ASEP) Coaching Certification (2001-present)