The Sound of Atherosclerosis: Voice Signal Characteristics are Independently Associated with Coronary Artery Disease
|
|
|
- Ruby Cain
- 5 years ago
- Views:
Transcription
1 The Sound of Atherosclerosis: Voice Signal Characteristics are Independently Associated with Coronary Artery Disease Elad Maor MD PhD 1, Jaskanwal D. Sara MBChB 1, Diana M. Orbelo, PhD 2, Lilach O. Lerman MD PhD 3 Yoram Levanon, DSc 4, Noa Silberklang 4, Yotam Luz, PhD 4, Daniella Perry, PhD 4, Amir Lerman MD 1 1 Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 2 Department of Otorhinolaryngology, Mayo Clinic, Rochester, MN 3 Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 4 Beyond Verbal Communications, Israel 2015 MFMER slide-1
2 Disclosure BeyondVerbal is a commercial company developing tools for voice analysis, including voice analysis tools for the diagnosis of disease states All other authors have nothing to disclose 2015 MFMER slide-2
3 Background Voice signal analysis is an emerging noninvasive diagnostic tool. Voice signal characteristics have been suggested to be associated with a number of different pathological entities including dyslexia, attention deficit hyperactive disorder, Parkinson s Disease and other neurological disorders 2015 MFMER slide-3
4 Study hypothesis and objectives We hypothesize that atherosclerosis process might involve anatomic structures associated with voice production The purpose of the current study was to identify association between voice characteristics and CAD among patients referred for coronary angiogram 2015 MFMER slide-4
5 Methods: study population 150 Patients (120 valid recordings) 21 Healthy Controls 120 Study patients 9 Non cardiac procedure controls Angiogram performed (N=117) Voice data and Angiogram (N=88) Normal coronaries (N=27) Coronary disease (N=61) 2015 MFMER slide-5
6 Methods Patients were asked to speak aloud a pre-determined amount of text into a recording device. Voice was recorded, stored online and analyzed for multiple features of voice intensity and frequency using "Beyond Verbal Communications" clinical trial smartphone application. Analysis was blinded with respect to patient data. A total of three 30 second separate baseline voice recordings were documented and analyzed for each participant: R1 participant was asked to read a prespecified text, R2 participant was asked to describe a positive experience and R3 description of a negative experience. The Mel Frequency Cepstral Coefficients (MFCCs) were used in order to extract information from the voice signal MFMER slide-6
7 Results Coronary Disease (N=61) Normal Coronaries (N=27) p Age 62±10 53± Male 36 (59%) 11 (41%).113 SBP 124±27 122± BMI 31±7 31±9.523 Hypertension 32 (53%) 8 (30%).047 Hyperlipidemia 31 (51%) 7 (26%).030 Diabetes Mellitus 11 (18%) 1 (4%).063 Sleep Apnea 16 (36%) 5 (19%).310 CKD 28 (46%) 5 (19%).014 ACS presentation 4 (7%) 2 (7%).916 Creatinine 0.9± ± Hemoglobin 14±2 14±2.779 Total Cholesterol 178±39 170± Triglycerides 142±77 99± LDL Cholesterol 103±37 95± HDL Cholesterol 47±18 56± Framingham Score 19±14 9± MFMER slide-7
8 Results: multivariate analysis OR 95% CI P Recording 1 Age Gender Feature Recording 2 Positive experience Age Gender Feature Feature Feature Feature Recording 3 Negative experience Age Gender Feature Feature Feature Feature MFMER slide-8
9 Results A multivariate binary logistic regression, with adjustment for age, gender, and cardiovascular traditional risk factors, showed that this features was independently associated with a significant 2.6-fold increased likelihood of CAD (95% CI , p=0.020). The red line for the CAD patient and green line for the control subject present the power spectrum density (PSD) of their speech frequencies expressed in the R3 recordings. The values were calculated by averaging over time the instantaneous PSD values calculated using Fourier transform on 25ms frames with 10ms shift 2015 MFMER slide-9
10 Conclusions This study suggests a potential relationship between voice characteristics and CAD. Voice features analysis holds the potential to assist physicians in estimating the pre-test probability of CAD among patients presenting with chest pain, especially in the setting of telemedicine when clinical health care is provided at a distance MFMER slide-10
Patient is healthy with no chronic disease or significant risk factors [16%].
![Patient is healthy with no chronic disease or significant risk factors [16%].](/thumbs/96/129036215.jpg "Patient is healthy with no chronic disease or significant risk factors [16%].")
AAFP Risk Level 1 Patient is healthy with no chronic disease or significant risk factors [16%]. Exclude the following chronic problems from active patient list o Depression o Diabetes Type I or Type II
The Impact of Smoking on Acute Ischemic Stroke
Smoking The Impact of Smoking on Acute Ischemic Stroke Wei-Chieh Weng, M.D. Department of Neurology, Chang-Gung Memorial Hospital, Kee-Lung, Taiwan Smoking related mortality Atherosclerotic vascular disease
Coronary artery disease (CAD) risk factors
Background Coronary artery disease (CAD) risk factors CAD Risk factors Hypertension Insulin resistance /diabetes Dyslipidemia Smoking /Obesity Male gender/ Old age Atherosclerosis Arterial stiffness precedes
Autonomic nervous system, inflammation and preclinical carotid atherosclerosis in depressed subjects with coronary risk factors
Autonomic nervous system, inflammation and preclinical carotid atherosclerosis in depressed subjects with coronary risk factors Carmine Pizzi 1 ; Lamberto Manzoli 2, Stefano Mancini 3 ; Gigliola Bedetti
Statin therapy in patients with Mild to Moderate Coronary Stenosis by 64-slice Multidetector Coronary Computed Tomography
Statin therapy in patients with Mild to Moderate Coronary Stenosis by 64-slice Multidetector Coronary Computed Tomography Hyo Eun Park 1, Eun-Ju Chun 2, Sang-Il Choi 2, Soyeon Ahn 2, Hyung-Kwan Kim 3,
Serum levels of galectin-1, galectin-3, and galectin-9 are associated with large artery atherosclerotic
Supplementary Information The title of the manuscript Serum levels of galectin-1, galectin-3, and galectin-9 are associated with large artery atherosclerotic stroke Xin-Wei He 1, Wei-Ling Li 1, Cai Li
Impact of Body Mass Index and Metabolic Syndrome on the Characteristics of Coronary Plaques Using Computed Tomography Angiography
Impact of Body Mass Index and Metabolic Syndrome on the Characteristics of Coronary Plaques Using Computed Tomography Angiography Cardiovascular Division, Faculty of Medicine, University of Tsukuba Akira
Radiological Tests: Which One is Most Appropriate for My Patient?
Radiological Tests: Which One is Most Appropriate for My Patient? Robert Hartman, M.D. 2016 MFMER slide-1 Disclosures No Disclosures 2016 MFMER slide-2 Objectives Discuss tools to aid in the ordering of
Cardiovascular Diseases in CKD
1 Cardiovascular Diseases in CKD Hung-Chun Chen, MD, PhD. Kaohsiung Medical University Taiwan Society of Nephrology 1 2 High Prevalence of CVD in CKD & ESRD Foley RN et al, AJKD 1998; 32(suppl 3):S112-9
Comparability of patient-reported health status: multi-country analysis of EQ-5D responses in patients with type 2 diabetes
Comparability of patient-reported health status: multi-country analysis of EQ-5D responses in patients with type 2 diabetes Joshua A Salomon, Anushka Patel, Bruce Neal, Paul Glasziou, Diederick E. Grobbee,
Effects of Kidney Disease on Cardiovascular Morbidity and Mortality
Effects of Kidney Disease on Cardiovascular Morbidity and Mortality Joachim H. Ix, MD, MAS Assistant Professor in Residence Division of Nephrology University of California San Diego, and Veterans Affairs
Endothelial Function Assessment in Secondary Prevention
Endothelial Function Assessment in Secondary Prevention Amir Lerman, MD Professor of Medicine Chair for Research Cardiovascular Division 2014 MFMER 3319523-1 Multiple Risk Factors 58-y.o. man with CV risk
Small dense low-density lipoprotein is a risk for coronary artery disease in an urban Japanese cohort: The Suita study
Small dense low-density lipoprotein is a risk for coronary artery disease in an urban Japanese cohort: The Suita study Hidenori Arai 1, Yoshihiro Kokubo 2, Makoto Watanabe 2, Tatsuya Sawamura 3, Tomonori
Contemporary management of Dyslipidemia
Contemporary management of Dyslipidemia Todd Anderson Feb 2018 Disclosure Statement Within the past two years: I have not had an affiliation (financial or otherwise) with a commercial organization that
Cardiac CT for Risk Assessment: Do we need to look beyond Coronary Artery Calcification
Cardiac CT for Risk Assessment: Do we need to look beyond Coronary Artery Calcification Matthew Budoff, MD, FACC, FAHA Professor of Medicine Director, Cardiac CT Harbor-UCLA Medical Center, Torrance, CA
CVD Prevention, Who to Consider
Continuing Professional Development 3rd annual McGill CME Cruise September 20 27, 2015 CVD Prevention, Who to Consider Dr. Guy Tremblay Excellence in Health Care and Lifelong Learning Global CV risk assessment..
Emmanouil S. Brilakis 1{, Joseph P. McConnell 2, Ryan J. Lennon 3, Ahmad A. Elesber 1, Jeffrey G. Meyer 2, and Peter B. Berger 4 * Introduction
European Heart Journal (2005) 26, 137 144 doi:10.1093/eurheartj/ehi010 Clinical research Association of lipoprotein-associated phospholipase A2 levels with coronary artery disease risk factors, angiographic
1. Which one of the following patients does not need to be screened for hyperlipidemia:
Questions: 1. Which one of the following patients does not need to be screened for hyperlipidemia: a) Diabetes mellitus b) Hypertension c) Family history of premature coronary disease (first degree relatives:
NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE General practice Indicators for the NICE menu
NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE General practice Indicators for the NICE menu Indicator area: Pulse rhythm assessment for AF Indicator: NM146 Date: June 2017 Introduction There is evidence
Module 2. Global Cardiovascular Risk Assessment and Reduction in Women with Hypertension
Module 2 Global Cardiovascular Risk Assessment and Reduction in Women with Hypertension 1 Copyright 2017 by Sea Courses Inc. All rights reserved. No part of this document may be reproduced, copied, stored,
Shared Decision Making and Minimally Disruptive Medicine
Shared Decision Making and Minimally Disruptive Medicine Ian Hargraves JP Brito KER UNIT Center for Clinical and Translational Sciences Mayo Clinic Minimally Disruptive Medicine Effective Care that Fits
Association between RV Function in PPCM and LV Recovery & Clinical Outcome
Association between RV Function in PPCM and LV Recovery & Clinical Outcome Lori A Blauwet, MD, MA Associate Professor of Medicine Co-Director, Cardio-OB Clinic Mayo Clinic Rochester, MN USA 2016 MFMER
Using Coronary Artery Calcium Score in the Quest for Cardiac Health. Robert J. Hage, D.O.
Using Coronary Artery Calcium Score in the Quest for Cardiac Health Robert J. Hage, D.O. Heart disease is the leading cause of death in the United States in both men and women. About 610,000 people die
Managing Dyslipidemia in Disclosures. Learning Objectives 03/05/2018. Speaker Disclosures
Managing Dyslipidemia in 2018 Glen J. Pearson, BSc, BScPhm, PharmD, FCSHP, FCCS Professor of Medicine (Cardiology) Co-Director, Cardiac Transplant Clinic; Associate Chair, Health Research Ethics Boards;
Disclosures. May 15 th, Influenza Vaccination as Secondary Prevention for Acute Coronary Events Where do we need to go in clinical practice?
Influenza Vaccination as Secondary Prevention for Acute Coronary Events Where do we need to go in clinical practice? May 15 th, 2014 Robi Goswami, MD Cardiologist Piedmont Heart Institute Disclosures None
Patient referral for elective coronary angiography: challenging the current strategy
Patient referral for elective coronary angiography: challenging the current strategy M. Santos, A. Ferreira, A. P. Sousa, J. Brito, R. Calé, L. Raposo, P. Gonçalves, R. Teles, M. Almeida, M. Mendes Cardiology
Noninvasive Detection of Coronary Artery Disease Using Resting Phase Signals and Advanced Machine Learning
Noninvasive Detection of Coronary Artery Disease Using Resting Phase Signals and Advanced Machine Learning Thomas D. Stuckey, MD FACC, FSCAI Medical Director/Section Chief LeBauer-Brodie Center for Cardiovascular
DECLARATION OF CONFLICT OF INTEREST. None
DECLARATION OF CONFLICT OF INTEREST None Plasma Lipidomic Analysis of Stable and Unstable Coronary Artery Disease Peter J Meikle 1, Gerard Wong 1, Despina Tsorotes 1, Christopher K Barlow 1, Jacquelyn
Low ALT Levels Independently Associated with 22-Year All-Cause Mortality Among Coronary Heart Disease Patients
Low ALT Levels Independently Associated with 22-Year All-Cause Mortality Among Coronary Heart Disease Patients N. Peltz-Sinvani, MD 1,4,R.Klempfner,MD 2,4, E. Ramaty, MD 1,4,B.A.Sela,PhD 3,4,I.Goldenberg,MD
Complex Thoracic and Abdominal Aortic Repair Using Hybrid Techniques
Complex Thoracic and Abdominal Aortic Repair Using Hybrid Techniques Tariq Almerey MD, January Moore BA, Houssam Farres MD, Richard Agnew MD, W. Andrew Oldenburg MD, Albert Hakaim MD Department of Vascular
CVD risk assessment using risk scores in primary and secondary prevention
CVD risk assessment using risk scores in primary and secondary prevention Raul D. Santos MD, PhD Heart Institute-InCor University of Sao Paulo Brazil Disclosure Honoraria for consulting and speaker activities
Supplementary Online Content
Supplementary Online Content Clair C, Rigotti NA, Porneala B, et al. Association of smoking cessation and weight change with cardiovascular disease among people with and without diabetes. JAMA. doi:10.1001/jama.2013.1644.
LDL cholesterol (p = 0.40). However, higher levels of HDL cholesterol (> or =1.5 mmol/l [60 mg/dl]) were associated with less progression of CAC
![LDL cholesterol (p = 0.40). However, higher levels of HDL cholesterol (> or =1.5 mmol/l [60 mg/dl]) were associated with less progression of CAC](/thumbs/88/116891773.jpg "LDL cholesterol (p = 0.40). However, higher levels of HDL cholesterol (> or =1.5 mmol/l [60 mg/dl]) were associated with less progression of CAC")
Am J Cardiol (2004);94:729-32 Relation of degree of physical activity to coronary artery calcium score in asymptomatic individuals with multiple metabolic risk factors M. Y. Desai, et al. Ciccarone Preventive
Supplementary Online Content. Abed HS, Wittert GA, Leong DP, et al. Effect of weight reduction and
1 Supplementary Online Content 2 3 4 5 6 Abed HS, Wittert GA, Leong DP, et al. Effect of weight reduction and cardiometabolic risk factor management on sympton burden and severity in patients with atrial
John J.P. Kastelein MD PhD Professor of Medicine Dept. of Vascular Medicine Academic Medial Center / University of Amsterdam
Latest Insights from the JUPITER Study John J.P. Kastelein MD PhD Professor of Medicine Dept. of Vascular Medicine Academic Medial Center / University of Amsterdam Inflammation, hscrp, and Vascular Prevention
Intercommunale de Santé Publique du Pays de Charleroi, Charleroi, Belgium 2
Lipid Abnormalities Remain High among Treated Hypertensive Patients with Stable CHD: Results of the Dyslipidemia International Study (DYSIS) II Belgium Michel Guillaume 1, Eric Weber 2, Johan De Sutter
HDL-C. J Jpn Coll Angiol, 2008, 48: NIPPON DATA80, MEGA study, JELIS, dyslipidemia, risk assessment chart
Online publication March 25, 2009 48 6 2007 2007 HDL-C LDL-C HDL-C J Jpn Coll Angiol, 2008, 48: 463 470 NIPPON DATA80, MEGA study, JELIS, dyslipidemia, risk assessment chart 1987 NIPPON DATA80 Iso 10 MRFIT
Dr Sandra Birchem Cardiologist Cardiovascular Division Mayo Clinic Rochester and Mayo Clinic Health System MFMER slide-1
Dr Sandra Birchem Cardiologist Cardiovascular Division Mayo Clinic Rochester and Mayo Clinic Health System 2011 MFMER slide-1 Heart Disease in Women and Why we are concerned 6,600,000 US women >440,000
Relationship between serum glutathione peroxidase-1activity with endothelial dysfunction level in patients with coronary artery diseases
Relationship between serum glutathione peroxidase-1activity with endothelial dysfunction level in patients with coronary artery diseases Introduction Reactive oxygen species (ROS),such as superoxide and
JUPITER NEJM Poll. Panel Discussion: Literature that Should Have an Impact on our Practice: The JUPITER Study
Panel Discussion: Literature that Should Have an Impact on our Practice: The Study Kaiser COAST 11 th Annual Conference Maui, August 2009 Robert Blumberg, MD, FACC Ralph Brindis, MD, MPH, FACC Primary
Metabolic Syndrome and Chronic Kidney Disease
Metabolic Syndrome and Chronic Kidney Disease Definition of Metabolic Syndrome National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III Abdominal obesity, defined as a waist circumference
Long-term prognostic value of N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) changes within one year in patients with coronary heart disease
Long-term prognostic value of N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) changes within one year in patients with coronary heart disease D. Dallmeier 1, D. Rothenbacher 2, W. Koenig 1, H. Brenner
GALECTIN-3 PREDICTS LONG TERM CARDIOVASCULAR DEATH IN HIGH-RISK CORONARY ARTERY DISEASE PATIENTS
GALECTIN-3 PREDICTS LONG TERM CARDIOVASCULAR DEATH IN HIGH-RISK CORONARY ARTERY DISEASE PATIENTS Table of Contents List of authors pag 2 Supplemental figure I pag 3 Supplemental figure II pag 4 Supplemental
Population Health Colloquium
Population Health Colloquium A Consumer-Oriented Perspective to Achieving Population Health March 28, 2017 2016 RedBrick Health Corporation. Not for unauthorized duplication or distribution. Agenda Patients
Supplementary Appendix
Supplementary Appendix This appendix has been provided by the authors to give readers additional information about their work. Supplement to: Solomon SD, Uno H, Lewis EF, et al. Erythropoietic response
Effective Date: TBD Version: 1.0 (Revised: 6/11/2014)
Protocol Title: Hypertension Effective Date: TBD Version: 1.0 (Revised: 6/11/2014) Approval By: TBD Planned Review Date: TBD 1 Purpose & Objective This protocol provides evidence-based care recommendations
Kathryn M. Rexrode, MD, MPH. Assistant Professor. Division of Preventive Medicine Brigham and Women s s Hospital Harvard Medical School
Update: Hormones and Cardiovascular Disease in Women Kathryn M. Rexrode, MD, MPH Assistant Professor Division of Preventive Medicine Brigham and Women s s Hospital Harvard Medical School Overview Review
Welcome and Introduction
Welcome and Introduction This presentation will: Define obesity, prediabetes, and diabetes Discuss the diagnoses and management of obesity, prediabetes, and diabetes Explain the early risk factors for
Supplementary Online Content
Supplementary Online Content Leibowitz M, Karpati T, Cohen-Stavi CJ, et al. Association between achieved low-density lipoprotein levels and major adverse cardiac events in patients with stable ischemic
!!! Aggregate Report Fasting Biometric Screening CLIENT!XXXX. May 2, ,000 participants
Aggregate Report Fasting Biometric Screening CLIENTXXXX May 2, 2014 21,000 participants Contact:404.636.9437~Website:www.atlantahealthsys.com RISK FACTOR QUESTIONNAIRE Participants Percent Do not exercise
David Ramenofsky, MD Bryan Kestenbaum, MD
Association of Serum Phosphate Concentration with Vascular Calcification in Patients Free of Chronic Kidney Disease: The Multi Ethnic Study of Atherosclerosis David Ramenofsky, MD Bryan Kestenbaum, MD
2017 Employee Wellness Health Assessment Report
Employee Wellness National Consortium for Building Healthy Academic Communities (BHAC) Healthier Tennessee Workplace 2017 Employee Wellness Health Assessment Report Blood Pressure 2017 (387 total) (National
Correlation of novel cardiac marker
Correlation of novel cardiac marker and mortality in EGAT population. Soluble ST2 hscrp Poh Chanyavanich, MD SukitYamwong, MD Piyamitr Sritara, MD Ramathibodi hospital Background hscrp - the most widely
Clinical Study Age Differences in Long Term Outcomes of Coronary Patients Treated with Drug Eluting Stents at a Tertiary Medical Center
Aging Research Volume 2013, Article ID 471026, 4 pages http://dx.doi.org/10.1155/2013/471026 Clinical Study Age Differences in Long Term Outcomes of Coronary Patients Treated with Drug Eluting Stents at
Preventive Cardiology
Preventive Cardiology 21 Volume The Preventive Cardiology and Rehabilitation Prevention Outpatient Visits 7,876 Program helps patients identify traditional and Phase I Rehab 9,932 emerging nontraditional
SUPPLEMENTAL MATERIAL. Supplemental Methods. Duke CAD Index
SUPPLEMENTAL MATERIAL Supplemental Methods Duke CAD Index The Duke CAD index, originally developed by David F. Kong, is an angiographic score that hierarchically assigns prognostic weights (0-100) based
Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University, Osaka, Japan. 4
146 Journal of Atherosclerosis and Thrombosis Original Articles Vol. 11, No. 3 Clinical Features of Familial Hypercholesterolemia in Japan in a Database from 1996 1998 by the Research Committee of the
Logistic Regression Predicting the Chances of Coronary Heart Disease. Multivariate Solutions
Logistic Regression Predicting the Chances of Coronary Heart Disease Multivariate Solutions What is Logistic Regression? Logistic regression in a nutshell: Logistic regression is used for prediction of
Triglyceride and HDL-C Dyslipidemia and Risks of Coronary Heart Disease and Ischemic Stroke by Glycemic Dysregulation Status: The Strong Heart Study
1/5 Triglyceride and HDL-C Dyslipidemia and Risks of Coronary Heart Disease and Ischemic Stroke by Glycemic Dysregulation Status: The Strong Heart Study Jennifer S. Lee, Po-Yin Chang, Ying Zhang, Jorge
Zhao Y Y et al. Ann Intern Med 2012;156:
Zhao Y Y et al. Ann Intern Med 2012;156:560-569 Introduction Fibrates are commonly prescribed to treat dyslipidemia An increase in serum creatinine level after use has been observed in randomized, placebocontrolled
6/10/2016. Hui-Chun Hsu
Hui-Chun Hsu PhD, RN, CDE Chief, Department of Diabetes Management Lee s Endocrinology Clinic Pingtung, Taiwan Disclosure to Participants Conflict of Interest (COI) and Financial Relationship Disclosures:
WIN QUARTERLY UTILIZATION REPORT 7/1/2010 TO 12/31/2010. EXPERTISE PARTNERSHIP V A L U E April 20, 2011
WIN QUARTERLY UTILIZATION REPORT 7/1/2010 TO 12/31/2010 EXPERTISE PARTNERSHIP V A L U E April 20, 2011 T R E N D S A N A L Y S I S S T A T I S T I C S P L A N N I N G T O O L S Participation Mass Screening
Supplementary Note Details of the patient populations studied Strengths and weakness of the study
Supplementary Note Details of the patient populations studied TVD and NCA patients. Patients were recruited to the TVD (triple vessel disease) group who had significant coronary artery disease (defined
HIV Infection as a Chronic Disease. Howard Libman, MD Beth Israel Deaconess Medical Center Harvard Medical School
HIV Infection as a Chronic Disease Howard Libman, MD Beth Israel Deaconess Medical Center Harvard Medical School Role of Primary Care Approximately 50,000 patients are diagnosed with HIV infection annually
2/9/2017. Financial Disclosures/Unapproved Use. Achieving Harmony in Blood Pressure Guidelines Around the Globe. Roger S. Blumenthal, MD.
Achieving Harmony in Blood Pressure Guidelines Around the Globe Roger S. Blumenthal, MD The Kenneth Jay Pollin Professor of Cardiology Director, The Johns Hopkins Ciccarone Center for the Prevention Of
Apelin and Visfatin Plasma Levels in Healthy Individuals With High Normal Blood Pressure
Apelin and Visfatin Plasma Levels in Healthy Individuals With High Normal Blood Pressure CI Liakos, 1 EA Sanidas, 1 DN Perrea, 1 V Gennimata, 1 V Chantziara, 1 CA Grassos, 2 N-A Viniou, 1 JD Barbetseas,
ARIC Manuscript Proposal # PC Reviewed: 2/10/09 Status: A Priority: 2 SC Reviewed: Status: Priority:
ARIC Manuscript Proposal # 1475 PC Reviewed: 2/10/09 Status: A Priority: 2 SC Reviewed: Status: Priority: 1.a. Full Title: Hypertension, left ventricular hypertrophy, and risk of incident hospitalized
Supplementary Online Content
Supplementary Online Content Anagnostou E, Aman MG, Handen BL, et al. Metformin for treatment of overweight induced by atypical antipsychotic medication in young people with autistic spectrum disorder:
LDL Cholesterol Lowering with Evolocumab and Outcomes in Patients with Peripheral Artery Disease: Insights from the FOURIER Trial
LDL Cholesterol Lowering with Evolocumab and Outcomes in Patients with Peripheral Artery Disease: Insights from the FOURIER Trial Marc P. Bonaca, Patrice Nault, Robert P. Giugliano, Anthony C. Keech, Armando
Metabolic Syndrome Is A Key Determinant Of Coronary Microvascular Function In Patients With Stable Coronary Disease Undergoing PCI
Metabolic Syndrome Is A Key Determinant Of Coronary Microvascular Function In Patients With Stable Coronary Disease Undergoing PCI Narbeh Melikian*, Ajay M Shah*, Martyn R Thomas, Roy Sherwood, Mark T
Diagnostic and Prognostic Value of Coronary Ca Score
Diagnostic and Prognostic Value of Coronary Ca Score Dr. Ghormallah Alzahrani Cardiac imaging division, Adult Cardiology department Prince Sultan Cardiac Center ( PSCC) Madina, June 2 Coronary Calcium
4/4/17 HYPERTENSION TARGETS: WHAT DO WE DO NOW? SET THE STAGE BP IN CLINICAL TRIALS?
HYPERTENSION TARGETS: WHAT DO WE DO NOW? MICHAEL LEFEVRE, MD, MSPH PROFESSOR AND VICE CHAIR DEPARTMENT OF FAMILY AND COMMUNITY MEDICINE UNIVERSITY OF MISSOURI 4/4/17 DISCLOSURE: MEMBER OF THE JNC 8 PANEL
MPS and Calcium Score in asymptomatic patient F. Mut, J. Vitola
MPS and Calcium Score in asymptomatic patient F. Mut, J. Vitola Nuclear Medicine Service, Asociacion Española Montevideo, Uruguay Quanta Diagnostico Nuclear Curitiba, Brazil Clinical history Male 63 y.o.,
Table 1 Baseline characteristics of 60 hemodialysis patients with atrial fibrillation and warfarin use
Table 1 Baseline characteristics of 60 hemodialysis patients with atrial fibrillation and warfarin use Baseline characteristics Users (n = 28) Non-users (n = 32) P value Age (years) 67.8 (9.4) 68.4 (8.5)
Sleep Apnea: Vascular and Metabolic Complications
Sleep Apnea: Vascular and Metabolic Complications Vahid Mohsenin, M.D. Professor of Medicine Yale University School of Medicine Director, Yale Center for Sleep Medicine Definitions Apnea: Cessation of
LEPTIN AS A NOVEL PREDICTOR OF DEPRESSION IN PATIENTS WITH THE METABOLIC SYNDROME
LEPTIN AS A NOVEL PREDICTOR OF DEPRESSION IN PATIENTS WITH THE METABOLIC SYNDROME Diana A. Chirinos, Ronald Goldberg, Elias Querales-Mago, Miriam Gutt, Judith R. McCalla, Marc Gellman and Neil Schneiderman
Table S1. Characteristics associated with frequency of nut consumption (full entire sample; Nn=4,416).
Table S1. Characteristics associated with frequency of nut (full entire sample; Nn=4,416). Daily nut Nn= 212 Weekly nut Nn= 487 Monthly nut Nn= 1,276 Infrequent or never nut Nn= 2,441 Sex; n (%) men 52
Improved control for confounding using propensity scores and instrumental variables?
Improved control for confounding using propensity scores and instrumental variables? Dr. Olaf H.Klungel Dept. of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute of Pharmaceutical Sciences
National public health campaigns have attempted
WINTER 2005 PREVENTIVE CARDIOLOGY 11 CLINICAL STUDY Knowledge of Cholesterol Levels and Targets in Patients With Coronary Artery Disease Susan Cheng, MD; 1,2 Judith H. Lichtman, MPH, PhD; 3 Joan M. Amatruda,
Supplement materials:
Supplement materials: Table S1: ICD-9 codes used to define prevalent comorbid conditions and incident conditions Comorbid condition ICD-9 code Hypertension 401-405 Diabetes mellitus 250.x Myocardial infarction
ZEUS Trial ezetimibe Ultrasound Study
Trial The lower, The better Is it True for Plaque Regression? Statin alone versus Combination of Ezetimibe and Statin Juntendo University, Department of Cardiology, Tokyo, Japan Katsumi Miyauchi, Naohisa
EMOTION CLASSIFICATION: HOW DOES AN AUTOMATED SYSTEM COMPARE TO NAÏVE HUMAN CODERS?
EMOTION CLASSIFICATION: HOW DOES AN AUTOMATED SYSTEM COMPARE TO NAÏVE HUMAN CODERS? Sefik Emre Eskimez, Kenneth Imade, Na Yang, Melissa Sturge- Apple, Zhiyao Duan, Wendi Heinzelman University of Rochester,
Unraveling the concealed and calculated cardiovascular risks in diabetes
15 P B Fernando Memorial Oration 2015 Unraveling the concealed and calculated cardiovascular risks in diabetes Weerarathna T P 1 Journal of the Ceylon College of Physicians, 2016, 47, 15-19 Abstract Cardiovascular
A: Epidemiology update. Evidence that LDL-C and CRP identify different high-risk groups
A: Epidemiology update Evidence that LDL-C and CRP identify different high-risk groups Women (n = 27,939; mean age 54.7 years) who were free of symptomatic cardiovascular (CV) disease at baseline were
The JUPITER trial: What does it tell us? Alice Y.Y. Cheng, MD, FRCPC January 24, 2009
The JUPITER trial: What does it tell us? Alice Y.Y. Cheng, MD, FRCPC January 24, 2009 Learning Objectives 1. Understand the role of statin therapy in the primary and secondary prevention of stroke 2. Explain
Arterial Age and Shift Work
340 Arterial Age and Shift Work Ioana Mozos 1*, Liliana Filimon 2 1 Department of Functional Sciences, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania 2 Department of Occupational
2013 Hypertension Measure Group Patient Visit Form
Please complete the form below for 20 or more unique patients meeting patient sample criteria for the measure group for the current reporting year. A majority (11 or more) patients must be Medicare Part
CARDIOVASCULAR RISK ASSESSMENT ADDITION OF CHRONIC KIDNEY DISEASE AND RACE TO THE FRAMINGHAM EQUATION PAUL E. DRAWZ, MD, MHS
CARDIOVASCULAR RISK ASSESSMENT ADDITION OF CHRONIC KIDNEY DISEASE AND RACE TO THE FRAMINGHAM EQUATION by PAUL E. DRAWZ, MD, MHS Submitted in partial fulfillment of the requirements for the degree of Master
Research Article The Effect of Elevated Triglycerides on the Onset and Progression of Coronary Artery Disease: A Retrospective Chart Review
Cholesterol Volume 2015, Article ID 292935, 5 pages http://dx.doi.org/10.1155/2015/292935 Research Article The Effect of Elevated Triglycerides on the Onset and Progression of Coronary Artery Disease:
Diabetes and Cardiovascular risk factors among Oil Sector Workers in the State of Kuwait (2013 KOC Periodical Medical Exam.)
Diabetes and Cardiovascular risk factors among Oil Sector Workers in the State of Kuwait (2013 KOC Periodical Medical Exam.) Mohammad Hasan, RN, CMIOSH Brief about KOC Kuwait Oil Company (KOC) is a state
SUPPLEMENTARY DATA. Supplementary Figure S1. Cohort definition flow chart.
Supplementary Figure S1. Cohort definition flow chart. Supplementary Table S1. Baseline characteristics of study population grouped according to having developed incident CKD during the follow-up or not
Optimizing risk assessment of total cardiovascular risk What are the tools? Lars Rydén Professor Karolinska Institutet Stockholm, Sweden
Optimizing risk assessment of total cardiovascular risk What are the tools? Lars Rydén Professor Karolinska Institutet Stockholm, Sweden Cardiovascular Disease Prevention (CVD) Three Strategies for CVD
Team members: Felix Krainski, Besiana Liti, William Lane Duvall (ASNC member)
ASNC Choosing Wisely Challenge 2016 An outpatient pathway for chest pain visits to the emergency department reduces length of stay, radiation exposure, and is patient-centered, safe and cost-effective.
Cardiovascular Controversies: Emerging Therapies for Lowering Cardiovascular Risk
Transcript Details This is a transcript of a continuing medical education (CME) activity accessible on the ReachMD network. Additional media formats for the activity and full activity details (including
ORIGINAL INVESTIGATION. C-Reactive Protein Concentration and Incident Hypertension in Young Adults
ORIGINAL INVESTIGATION C-Reactive Protein Concentration and Incident Hypertension in Young Adults The CARDIA Study Susan G. Lakoski, MD, MS; David M. Herrington, MD, MHS; David M. Siscovick, MD, MPH; Stephen
Coronary Artery Calcium Scoring Mirvat Alasnag FACP, FRCP, FSCCT, FSCAI, FASE King Fahd Armed Forces Hospital, Jeddah. March 2017
Coronary Artery Calcium Scoring Mirvat Alasnag FACP, FRCP, FSCCT, FSCAI, FASE King Fahd Armed Forces Hospital, Jeddah March 2017 Newspapers Referrals 62 year old female CT chest and abdomen following
Supplementary Online Content
1 Supplementary Online Content Friedman DJ, Piccini JP, Wang T, et al. Association between left atrial appendage occlusion and readmission for thromboembolism among patients with atrial fibrillation undergoing
Disclosures. Diabetes and Cardiovascular Risk Management. Learning Objectives. Atherosclerotic Cardiovascular Disease
Disclosures Diabetes and Cardiovascular Risk Management Tony Hampton, MD, MBA Medical Director Advocate Aurora Operating System Advocate Aurora Healthcare Downers Grove, IL No conflicts or disclosures
JNC Evidence-Based Guidelines for the Management of High Blood Pressure in Adults
JNC 8 2014 Evidence-Based Guidelines for the Management of High Blood Pressure in Adults Table of Contents Why Do We Treat Hypertension? Blood Pressure Treatment Goals Initial Therapy Strength of Recommendation