The subject is composed from theoretical lectures and clinical practicals.

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1 Published on Second Faculty of Medicine, Charles University ( Internal Medicine I Submitted by Marie Havlová on 28. August :00 Syllabus of Internal Medicine I The subject is composed from theoretical lectures and clinical practicals. Practicals are run on wards of Internal Clinic. Start of lectures and practicals is specified in time schedule. Students may check which meeting room/ward is assigned to their class: faculty website study time schedules click on respective study group on a noticeboard on the floor 4D (in front of the secretariat of Internal Clinic) Syllabus of lectures of Internal Medicine I Pulmonology: 1. Emergency situation in pulmonology The presentation gives an overview of emergency situations in pneumology, their etiology, pathogenesis, clinical features, diagnosis and Particular attention is paid to imaging methods. 2. Bronchoscopy Overview of indications, types, complications and benefits of this important examination. 3. Acute and chronic respiratory insufficiency The lecture deals with the definition, pathophysiology, clinical presentation, diagnostic approaches and therapeutic measures in conditions associated with respiratory insufficiency.

2 4. COPD Etiology, pathophysiology, risk factors. Clinical presentation, physical examination, functional testing, imaging methods. Therapy and importance of non-smoking. 5. Dyspnoe The presentation gives an overview of the etiology, pathogenesis, clinical features, differential diagnosis and treatment of dyspnoea. Particular attention is paid to imaging methods. 6. Asthma bronchiale The presentation gives an overview of the definition, etiology, pathogenesis, clinical features, diagnosis, classification and treatment of bronchial asthma. The latest international guidelines are considered (GINA). 7. Interstitial lung diseases The lecture deals with the definition, pathophysiology, clinical presentation, diagnostic approaches and therapeutic measures in interstitial pulmonary processes, as disease model is discussed sarcoidosis in detail. Idiopathic pulmonary fibrosis the presentation gives an overview of the epidemiology, etiology, pathogenesis, clinical features, diagnosis and treatment of idiopathic pulmonary fibrosis. Particular attention is paid to imaging methods. 8. Haemopthysis pathogenesis, clinical features, differential diagnosis and treatment of haemoptysis. Particular attention is paid to imaging methods. 9. Pneumonias pathogenesis, clinical features, diagnosis and treatment of community acquired and hospital acquired pneumonia and pneumonia in immunocompromited host. Particular attention is paid to imaging methods.

3 10. Pleural effusion pathogenesis, clinical features, diagnosis and treatment of pleural effusion. Particular attention is paid to imaging methods. 11. Tuberculosis pathogenesis, clinical features, diagnosis and treatment of tuberculosis. Particular attention is paid to new methods of diagnosis of latent tuberculosis, vaccination and other measures of control of tuberculosis., microbiology of tbc 12. Lung cancer pathogenesis, clinical features, diagnosis and treatment of lung cancer. Particular attention is paid to imaging methods and prevention of this disease. Gastroenterology: 1. Examination methods in gastroenterology and hematology History, common complaints. Physical examination. Ultrasound, X-ray, CT and MR imaging. Endoscopic and biochemical methods. 2. Gastroesophageal reflux disease. Peptic ulcer of stomach and duodenum. Tumours of stomach. The presentation gives an overview of the epidemiology, etiology, pathogenesis, clinical features, diagnosis and treatment of Gastroesophageal reflux disease, peptic ulcers and stomach tumours. Particular attention is paid to imaging methods and prevention of this disease.

4 3. Inflammatory bowel disease pathogenesis, clinical features, diagnosis and treatment of inflammatory bowel disease. Particular attention is paid to imaging methods. 4. Intestinal polyps, cancer of large intestine and rectum pathogenesis, clinical features, diagnosis and treatment of intestinal polyps and cancer. Particular attention is paid to imaging methods, screening and prevention of this disease. 5. Gastrointestinal bleeding, chronic pancreatitis Acute bleeding to the gastrointestinal tract, main clinical symptoms, differences in clinical symptomatology dependent on etiology of the bleeding. Importance of circulation stabilization, endoscopy methods for examination and Chronic pancreatitis definition, pathogenesis, etiology. Risk factors, clinical presentation, physical examination, lab results and imaging methods. Treatment. 6. Cholelithiasis and its complications Definition: Cholecystolithiasis biliary stones in the gallbladder, choledocholithiasis biliary stones in the common bile duct and hepatic duct. Incidence, etiology, clinical presentation, laboratory results, imaging methods, therapy. Required knowledge: anatomy, physiology of hepatobiliary area 7. Chronic hepatitis, cirrhosis of the liver Definition, ethiology and pathophysiology. Viral, autoimmune and other chronic hepatitis. Diagnosis, imaging methods, treatment and complications of this disease. Liver cirrhosis etiology, pathophysiology, clinical presentation, lab and imaging methods. Treatment and complications. Required knowledge: anatomy, physiology of liver 8. Portal hypertension, hepatic failure Definition, anatomy and pathophysiology of portal hypertension. Ethiology, diagnostics, clinical presentation, complications and therapy. Definition and

5 incidence of liver failure, ethiology and pathophysiology, complications, diagnosis and Required knowledge: anatomy, physiology of liver 9. Differential diagnosis of jaundice (as. Lochmannová) Review of basic types of icterus, (prehepatal, hepatal, posthepatal), clinical presentation, lab results, imaging methods. Case reports. Required knowledge: anatomy, physiology of liver 10. Differential diagnosis of fever states (as. Holá) Pathophysiological of temperature, types of temperature, diagnostic methods. Febrile states by etiology: infectional, tumors, systematic disease. Subfebrile states, invasive methods as febrile source. Required knowledge: physiological and Pathophysiological knowledge of thermoregulation Diabetology a metabolism: 1. Diabetes mellitus part I Ethiology, pathogenesis, clinical presentation, diagnostic. Classification and differential diagnostics of diabetes. 2. Diabetes mellitus part II Acute and chronic diabetes complication. Clinical presentation, diagnostics and 3. Treatment of diabetes mellitus Treatment with oral antidiabetic agents and insulin Differences in treatment of type 1 and 2 diabetes. Diet and physical exercise. 4. Nutritional disorders (obesity, kachexia), hyperuricaemia, porphyria Definition, measurement, classification of obesity. Examination of an obese patient (history, specifics in obesity), function and distribution of adipose tissue, complication of obesity. Therapy (behavior modification, diet, exercise, psychotherapy, drugs, surgery). Definition, etiology of malnutrition, diagnostic and types, laboratory parameters, complications. Definition, pathogenesis,

6 clinical features of hyperuricaemia, artritis uratica, chronic gout, therapy. Definition, classification, clinical features of porphyria. 5. Disorders of lipid metabolism, atherosclerosis and endothelial dysfunction (as. Piťha) Dyslipidemia risks and classification. Goals for treatment, recommended targets for dyslipidemia Lab results. Atherosclerosis, endothelial dysfunction. Cardiology: 1. Acute coronary syndromes Ethiology, pathophysiology, risk factors. Clinical presentation, examination, diagnostics, 2. Atherosclerosis and chronic coronary heart disease Introductory lecture to clinical aspects of coronary heart disease (CHD) defining clinical forms of CHD. It defines principles of coronary circulation in a healthy individual, as well as normal functions of endothelium. Endothelial dysfunction is presented in relation to atherogenesis together with main risk factors of CHD. Of clinical forms of CHD, effort angina pectoris and silent ischemia are presented (clinical symptomatology, examinations, noninvasive and invasive treatment). 3. Valvular heart disease 4. Arrhythmias 5. Congestive heart failure

7 6. Cor pulmonale, pulmonary embolism 7. Hypertension 8. Shock Presentation composed of two parts. The general one defines symptoms and signs of shock, diagnostic principles, as well as general therapeutic possibilities. The second part presents cardiogenic shock in myocardial infarction, in pulmonary embolism and in cardiac tamponade. Oligemic shock is presented mainly in connections important for internal medicine. Distributory shock, septic and anaphylactic shock are presented. 9. Cardiomyopathies 10. Myocarditis, pericarditis, endocarditis 11. Differential diagnosis of chest pains 12. Basic ECG records Clinical presentation, basic ecg records of most important dysrhytmias.

8 13. Disorders of limb arteries and veins Ethiology, pathophysiology, risk factors of arterial and velus disease of peripheral vessels. Clinical presentation, imaging methods, A lead supervisor of teaching of Internal Medicine I is: prof. MUDr. Milan Kvapil, CSc., MBA Responsible person: as. MUDr. Pavlína Piťhová, Ph.D., tel , 4067 Source URL (retrieved on :10):

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