Urinary tract infection, Urinary pathogens.

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1 Kay words: Urinary tract infection, Urinary pathogens.

2 Fig. 1 Organisms commonly isolated and their incidence in the U.T.I. with bacterial TOTAL(NUMBER=1396) MALE(NUMBER=707) FEMALE(NUMBER=689) Fig. 2 Organisms commonly isolated and their incidence in the U.T.I. with bacterial INPATIENTS(NUMBER 96I) OUTPATIENTS(NUMBER=435) ADULT(NUMBER=1079) CHILDREN(NUMBER=3I9)

3 Fig. 3 Organisms commonly isolated and their incidence in the U.T.I. with bacterial ADULT, INPATIENTS. CHILDREN,INPATIENTS,

4 Fig. 4 Organisms commonly isolated and their incidence in the U.T.I. with bacterial

5 Fig. 5 Underlysing diseases in bacteriuria with bacterial count of more than 105/ml in urine. Table 1 Percentage of Bacterial Strains Isolated from Urine Susceptive to Various Antimicrobial Agents ABPC: Ampicillin; SBPC: Sulbenicillin; CEX: Cephalexin; CP: Chloramphenicol; NA: Nalidixic acid; MNC: Minocycline; PMX-B: Polymyxin B.

6 Fig. 6 Oargnisms commonly isolated and their incidence in the U. T. I. with bacterial Table 2 Percentage of Bacterial Strains Isolated from Urine Susceptive to Various Antimicrobial Agents.

7 Table 3 Percentage of Bacterial Strains Isolated from Urine Susceptive to Various Antimicrobial Agents.

8 Dis., 120: 1-12, ) J.M. Stansefeld: Duration of treatment for urinary tract infections in children. Br. Med. J., 12: 65-66, ) Freeman, R.B., Smith, W.M., Richardson, J.A., Hennelly, P.J., Thurm, R.H., Urner, C., Vaillancourt, J.A., Griep, R. J. and Bromer, L.: Long term therapy for chronic bacteriuria in men. Ann. Int. Med., 83: , ) Siegel, S.R., Sokoloff, B. and Siegel, B.: Asymptomatic and symptomatic urinary tract infection in infancy. Am. J. Dis. Child., 125: 45-47, ) Little, P.J.: The incidence of urinary infection in 5000 pregnant women. Lancet., 29: , ) Marple, C.D.: Frequency and character of urinary tract infections in unselected groups of women. Ann. Int. Med., 14: , ) Kass, E.H.: Chemotherapeutic and antibiotic drugs in management of infections of urinary tract. Am. J. Med., 18: , ) Kass, E.H.: Asymptomatic infections of urinary tract. Tr. A. Am. Physicians., 69: 59-64, ) Cox, C.E., Lacy, S.S. and Hinman, F. Jr.: The urethra and its relationship to urinary tract infection: 11 The urethral flora of the female with recurrent urinary infection. J. Urol., 99: , ) Harle, E.M. J., Bullen, J. J. and Thomson, D.A.: Influence of estrogen on experimental pyelonephritis caused by Escherichia coli. Lancet., 16: , ) Baker, R., Maxted, W., Maylath, J. and Shuman, I.: Relation of age, sex and infection to reflux: data indicating high spontaneous cure rate in pediatric patients. J. Urol., 95: 27-32, ) Miller, T.E. and Creaghe, E.: Bacterial interference as a factor in renal infection. J. Lab. Clin. Med., 87: , ) Gardner, P., Griffin, W.B., Swartz, M.N. and Kunz, L. J.: Nonfermentative gram-negative bacilli of nosocomial interest. Amer. J. Med., 48: , ) Hallet, R. J., Pead, L. and Maskell, R.: Urinary infection in boys. Lancet., 20: , ) Calvin M. Kunin: Epedermology of bacteriuria 15) Weyrauch, H.M. and Bassett, J.B.: Ascending and its relation to pyelonephritis. J. Infect. infection in an artificial urinary tract. An

9 experimental study. Stanf. Med. Bull., 9: 25-29, ) Keefe, W.E. and Smith, M. J.V. Intracellular crystalline deposits by bacteria grown in urine from a stone former. Invest. Urol., 14: , ) National nasocomial infections study report: Annual summary Atlanta, Center for disease control, 1977, pp ) McGowan, J.E. Jr. and Finland, M.: Infection and antibiotic usage at Boston City Hospital: changes in prevalence during the decade J. Infect. Dis., 129: , ) McCabe, W.R. and Jackson, G.G.: Gramnegative bacteremia. 1. Etiology and ecology. Arch. Intern. Med., 110: , Organisms Encountered in Urinary Tract Infections in the Various Groups of Patients and Antibiotic Sensitivities Takao NAGAI Central Clinical Laboratory, Kyoto University Hospital, Kyoto 606, Japan Urinary tract infections (UTI) have been investigated in 1082 patients (422 males and 660 females) of all ages with bacterial counts above 100,000 organisms per ml in urine. University of Kyoto Hospital between March, 1975 and February, The patients were seen at The organisms isolated from urine containing more than 100,000 bacteria per ml were surveyed after quantitative bacterial culture from mid-stream urine. The most frequently isolated bacteria in the patients overall were Escherischia coli (28%), Proteus spp. (15%), Pseudomonas aeruginosa (13%), and Klebsiella spp (12%). In male patients, Proteus spp. (20%) were most frequent, followed by E. coli (17%), Ps. aeruginosa (15%), Klebsiella spp. (13%), and enterococcus (13%). In female patients, E. coli (40%) was most frequent, followed by Proteus spp.(12%), Klebsiella spp. (11%), enterococcus (11%), and Ps. aeruginosa (10%). E. coli was the predominant isolate in females, both adults and children, being present in approximately 40% to 60% of positive cultures. In male patients, no isolate was predominant; the percentage of E. coli isolates was lower, and those of Proteus spp., Klebsiella spp., Ps. aeruginosa, and enterococcus werehigher than in females. In UTI in patient without underlying diseases, E. coli was the predominant isolate, being present in 40% of the positive cultures, while in patients with malignancy, the most frequent isolate was Ps. aeruginosa (20%), followed by E. coli (18%), enterococcus (18%) and Proteus spp (13%). And in UTI in patients with nephrolithiasis, Proteus spp. (25%) was the most frequent isolate, followed by E. coli (20%), Staphylococcus spp. (10%), Klebsiella spp. (10%), Enterobacter (10%), and Ps. aeruginosa (9%). spp.

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