Preservatives for personal care formulations

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1 Preservatives for personal care formulations

2

3 Dear Customer, The team of professionals of Chemipol S.A. we are pleased to share with you over thirty years of experience in microbiology, applied to the personal care, chemical and food industry, with the launch of our new catalog that includes the wide range of preservatives we manufacture for microbial control in personal care formulations. We would like to take this opportunity to thank the trust that many of you has been showing in us, as well as we would like to express how enriching is the cooperation between our companies which allows to improve the formulations brought to the consumer. This catalog has been prepared with the aim to serve as a guideline to facilitate your work related to the microbiology and preservation of personal care formulations. We hope that this catalog will allow us to strengthen further, if possible, the existing collaboration with customers and also serve as a starting point for those with whom are meeting for the first time. Thank you very much. Welcome to Chemipol!

4 Working for a sustainable life Chemipol is a chemical company established in 1979, manufacturer and supplier of a wide range of biocides, additives and process chemicals. We provide innovative technologies, highly effective products and expert support services through specialized technical sales groups with outstanding expertise in customer point of view. INDUSTRIES WE SUPPLY Personal care Household care Paints, coatings and inks Polymer emulsions Construction chemicals Agrochemical Paper Oilfield and fuel Industrial water cooling circuits and boilers Water desalination Waste water treatment Water purification PRODUCTS WE PROVIDE Preservatives and antimicrobials Plant hygiene products Performance additives Biocides Performance additives Pigments Decorative bases Biocides Performance additives Biocides Performance additives Process chemicals Biocides Performance additives Biocides Process chemicals Equipments and dosing systems

5 Product range for personal care Preservatives - BIOPOL classic preservatives - BIOPOL classic active ingredients - SENSICARE C and SENSICARE M preservatives with improved eco-toxicity Preservative-free antimicrobials - SENSICARE FP innovative antimicrobials for preservative-free products - SENSICARE NAT natural antimicrobials Plant hygiene solutions - SANIPOL plant sanitizers - BIOCHECK kit for microbiological check Plant hygiene solutions - ACRIPOL OP opacifiers - ACRIPOL T thickeners - DENSIPOL defoamers

6 Classic preservatives BIOPOL Based on the well-known classic active substances BIOPOL is a broad range of preservatives based on different combinations of classic active substances suitable for protection of all kind of leave-on and rinse-off products. Benefits to you - Low dosage. - Broad spectrum of activity. - Stable over a broad range of ph and different type of formulations. - Regulatory compliance.

7 Product INCI NAME Use guidelines ph Process temperature Typical dosage BIOPOL C 20 BIOPOL C 30 BIOPOL IBC Methylchloroisothiazolinone Methylisothiazolinone Methylchloroisothiazolinone Methylisothiazolinone Benzyl Alcohol Methylchloroisothiazolinone Methylisothiazolinone 2-Bromo-2-Nitropropane-1.3-Diol < 8 50ºC 0,05 0,10 % < 8 50ºC 0,05 0,20 % < 8 50ºC 0,05 0,10 % BIOPOL MI 10 Methylisothiazolinone < 10 80ºC 0,05 0,10 % BIOPOL MIH Methylisothiazolinone < 10 80ºC 0,20 0,40 % BIOPOL DHN DMDM Hydantoin < 10 60ºC 0,20 0,60 % BIOPOL DHI BIOPOL DHP BIOPOL DHK BIOPOL PB 6 BIOPOL PB 12 BIOPOL PB 17 DMDM Hydantoin Methylchloroisothiazolinone Methylisothiazolinone DMDM Hydantoin Iodopropynyl Butylcarbamate DMDM Hydantoin Potassium Sorbate Methylparaben Ethylparaben Propylparaben Methylparaben Ethylparaben Methylparaben Ethylparaben Glyceryl Laurate < 8 50 ºC 0,20 0,50 % < 10 60ºC 0,15 0,40 % < ºC 0,20 0,80 % < 8 80 ºC 0,20 1,00 % < 8 80 ºC 0,20 1,00 % < 8 80 ºC 0,20 0,80 % BIOPOL AB Benzyl Alcohol < 6 80 ºC 0,20 1,00 % BIOPOL BA Benzoic Acid < 6 80 ºC 0,20 0,60 % BIOPOL BR Bromo-2-Nitropropane-1.3-Diol < 8 50 ºC 0,02 0,10 % BIOPOL DA Dehydroacetic Acid < 6 80 ºC 0,20 0,60 % BIOPOL PB 1 Methylparaben < 8 80 ºC 0,20 0,40 % BIOPOL PB 2 Ethylparaben < 8 80 ºC 0,20 0,40 % BIOPOL PE < ºC 0,20 1,00 % BIOPOL DA Dehydroacetic Acid < 6 80 ºC 0,20 0,60 % BIOPOL PS Potassium Sorbate < 5,5 80 ºC 0,20 0,60 % BIOPOL SB Sodium Benzoate < 5,5 80 ºC 0,20 0,60 %

8 Innovative preservatives SENSICARE Intelligent microbial control SENSICARE range of products is the result of an on-going modern research program to develop innovative preservatives and antimicrobials for control microbial growth in personal care formulations. The use of SENSICARE enables to formulate cosmetic products by decreasing the concentration of preservative ingredients while ensuring the optimum protection in front harmful microorganisms. The lower presence of preservatives in the final formula minimizes its undesirable side effects such as sensitization and incompatibility with other raw materials. SENSICARE research program is supported by a large number of robust microbiological studies including Minimum Inhibitory Concentrations, Microbial Reduction Kinetics, Challenge Tests and Stability Tests in final formulations.

9 SENSICARE C Improved eco-toxicity preservatives Benefits to you - Cost-effective synergistic formulations. - Booster technology. - Reliable efficacy compared to classical preservatives. - Low potential for sensitization. - Options for different marketing requirements. Product SENSICARE C 1000 SENSICARE C 1010 SENSICARE C 1040 SENSICARE C 1042 SENSICARE C 1045 SENSICARE C 1052 SENSICARE C 1055 SENSICARE C 1060 SENSICARE C 1080 SENSICARE C 1090 SENSICARE C 2010 SENSICARE C 3000 SENSICARE C 3200 SENSICARE C 3300 SENSICARE C 3900 INCI NAME Glyceryl Laurate Glyceryl Laurate Methylisothiazolinone Benzoic Acid Dehydroacetic Acid Glyceryl Laurate Benzoic Acid Dehydroacetic Acid Ethylhexylglycerin Benzoic acid Dehydroacetic acid Phenoxyetanol Benzoic Acid Phenoxyetanol Benzoic Acid Sorbic Acid Glyceryl Laurate Piroctone Olamine Caprylyl Glycol Ethylhexylglycerin Sodium Benzoate Potassium Sorbate Dehydroacetic Acid Benzyl Alcohol Benzyl Alcohol Potassium Sorbate Benzyl Alcohol Glyceryl Laurate Benzyl Alcohol Ethylhexylglycerin Use guidelines ph Process temperature Typical dosage < 12 80ºC 0,60 1,10 % < 10 80ºC 0,15 0,40 % < 6 50ºC 0,50 1,30 % < 6 50ºC 0,50 1,30 % < 6 50ºC 0,50 1,30 % < 6 50ºC 0,50 1,30 % < 6 50ºC 0,50 1,30 % < 8 80ºC 0,40 1,10 % < 12 80ºC 0,70 1,10 % < 12 80ºC 0,70 1,10 % < ºC 0,50 1,50 % < 6 50ºC 0,60 1,10 % < 12 50ºC 0,60 1,10 % < 12 50ºC 0,60 1,10 % < 12 50ºC 0,60 1,10 %

10 Innovative preservatives SENSICARE M Preservatives and multifunctional additives Benefits to you - Booster technology. - Multifunctional properties. - Low potential for sensitization. - Options for different marketing requirements. Product Characteristics INCI Use guidelines ph Process temperature Typical dosage SENSICARE M 4200 SENSICARE M 8000 SENSICARE M 9000 Preservative, chelating, humectant and skin conditioning. ECOCERT Emollient, humectant and skin conditioning. Improves antimicrobials performance Skin conditioning. Improves antimicrobials performance. Gluconolactone Sodium Benzoate Calcium Gluconate < 7 80ºC 0,60 2,00 % Caprylyl Glycol < 11 80ºC 0,30 1,00 % Ethylhexylglycerin < ºC 0,30 1,00 %

11 SENSICARE FP Preservative-free antimicrobials Benefits to you - For preservative-free products - Effective against bacteria and fungi - For rinse off, emulsions and lotions - No side effects on final formulations Product SENSICARE FP 1 SENSICARE FP 2 Characteristics Synergistic combination of different synthetic active substances with boosters. Antimicrobial efficacy in front of bacteria, molds and yeasts. Synergistic combination of different synthetic active substances, glycols and booster. Antimicrobial efficacy in front of bacteria, molds and yeasts. Use guidelines ph Process temperature Typical dosage < 10 80ºC 1 2 % < 8 60ºC 1 2 % SENSICARE NAT Natural antimicrobials Benefits to you - Natural protection for Natural cosmetics - Effective against bacteria and fungi - ECOCERT and COSMOS compliant Product SENSICARE NAT Characteristics Synergistic combination of different natural extracts with antimicrobial activity in natural formulations. Use guidelines ph Process temperature Typical dosage < 10 80ºC 1 2 %

12 Application overview Product Face cleansing Face care Shaving products Body cleansing Body care Sun CATEGORY protection Hair cleansing Hair care Hair styling Decorative cosmetics Wet wipes BIOPOL C 20 BIOPOL C 30 BIOPOL MI 10 BIOPOL DHN BIOPOL DHI BIOPOL DHK SENSICARE C 1000 SENSICARE C 1010 SENSICARE C 1040 SENSICARE C 1060 SENSICARE C 3000 SENSICARE C 3300 SENSICARE M 4200 SENSICARE FP 1 SENSICARE FP 2 SENSICARE NAT Especially recommended Recommended Possible

13 Plant hygiene solutions Chemipol provides SANIPOL family that is integrated by a complete range of products for plant hygiene including cleansing products for removing production waste and sanitizing solutions for cleaning cosmetic production facilities, both manually and CIP systems. Product Description Application SANIPOL 103 Sanitizing biocide based on a formulation of organ-bromine compound (DBNPA). Quick disinfection of production facilities, circulating systems and filling systems in cosmetic, detergent and all type of automated production facilities (CIP). SANIPOL 125 Sanitizing biocide based on a mixture of methylchloroisothiazolinone, methylisothiazolinone, glutaraldehyde and non-ionic surfactants. Does not release formaldehyde. Sanitization of wide spectra especially indicated for avoiding the alterations caused by microorganisms in production facilities, circulating systems and filling systems in cosmetic, detergent and all type of automated production facilities (CIP). SANIPOL 250 Formulation based on polyelectrolyte derived from an acrylic polymer. Removal of residual pigments and fillers from production systems. It is ready for incorporation in situ in the cleaning solution.

14 BioCheck Agar kit for easy microbiological check The kit comprises a box with plastic two face dip slides coated each with agar mixture that inactivates the existing biocide and provides the necessary nutrients for the microorganisms growth after incubation period time. One side is ready for aerobic bacteria and the other for fungi/yeasts. BioCheck is recommended for checking the presence of microorganisms in products (raw materials, intermediate formulations and final products) as well as manufacturing facilities (surfaces). Benefits to you - Easy to use. - Quick microbiological check. - Versatile. Examples of how microorganism are seen in BioCheck : Bacteria Fungi 100 CFU/ml 10,000 CFU/ml 1 million CFU/ml 100 CFU/ml 10,000 CFU/ml 1 million CFU/ml

15 Our expert services for you Chemipol technical department provides expert support to customers worldwide: - A teamwork of chemists and microbiologists. - Three laboratories with specific techniques and equipment are located in the main site, what allow us to meet all needs related to the products and industries we supply fast, flexible and efficiently. - Ability of follow different standards worldwide and our own methods especially designed for each application. Microbial contamination causes well known problems associated to loss of product characteristics, problems in human health and loss of company image. With the objective of bringing to the consumer products in good microbiological conditions, we offer a comprehensive microbiology service. Plant Audits and Hygiene Programs Bacteria and fungi intrusion typically occurs during the industrial stage and in-use of cosmetic products. Our plant audits and hygiene programs helps you to remove microbial intrusion. These programs includes: On-site plant audits: checking of production facilities to identify critical points Risk removal: in consequence with the on-site plant audit results we recommend specific procedures and products to remove contamination: cleaning, disinfection, maintenance, training of staff (seminars, customer in-house practices). Microbiology Chemipol microbiological services include a test program according to different test guidelines and Chemipol expert standards including toxicological assessment. Our Microbiological Services includes: - Challenge tests (UNE 11930). - Cosmetic Challenge Test (CCT) - Determination of minimum inhibitory concentration (MIC). - Kinetics of decline. - Information on period after opening (PoA). - Stability tests. - Validation of new preservatives (incorporation, compatibility). - Comparative tests.

16 Chemipol in the world Algeria Austria Bahrain Belgium Bolivia Bulgaria Canada China Colombia Costa Rica Cyprus Czech Republic Denmark Ecuador Egypt Estonia Finland France Germany Ghana Greece Guatemala Indonesia Iran Iraq Ireland Israel Italy Ivory Coast Jordan Kenya Kuwait Latvia Lebanon Libya Lithuania Malaysia Malta Mexico Morocco Nigeria Norway Pakistan Philippines Poland Portugal Romania Russia Saudi Arabia Serbia Slovenia South Korea Spain Sudan Sweden Switzerland Syria Taiwan Thailand Tunisia Turkey Ukraine United Arab Emirates United Kingdom Vietnam Joan Monpeó, Terrassa (Barcelona) Spain Tel Fax: The information here contained and recommendations regarding our products are based on in-depth tests developed by our Technical Department. They are given in good faith as assistance to users and no liability can be derived from them. Variations can occur during product application and users are advised to test by themselves. Always read the label and product information before use. Please, contact us for further information. Moreover, apply our general conditions of sale available at Product Guide EN-COS

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