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1 Established in 1992, Shanghai Fosun High Technology (Group) Co., Ltd. ("Fosun") has now grown into the largest privately-owned conglomerate in China with HKSE Code: 00656HK. Fosun s business operations cover 5 segments including pharmaceuticals, property development, steel, mining, retail, services and strategic investments. In 2009, Fosun International recorded revenue of RMB billion(usd5.12 billion) and a net profit of RMB billion(usd657 million). Now Fosun has retained its position as No. 7 th among the Top 100 Chinese private enterprises in 2010 and it had been the largest taxpayer among Chinese private enterprises for 4 consecutive years. In 2009, Fosun ranked No. 81 in terms of net profit among Top 500 Chinese enterprises, No.2 in revenue among Chinese comprehensive manufacturing enterprises, No. 91 in revenue among Top 500 Chinese enterprises, No.58 among Top 500 China brands. Fosun enjoys steady growth in its portfolio companies which are, in most cases, among the top 10 players in these industries. Suzhou Laishi Transfusion Equipment Co., Ltd (LAISHI) became an independent company in 1992, with a root going back to 1960s with founding of transfusion Laboratories under Shanghai Blood Center. It is aiming to protect the safety of blood transfusion by developing medical devices and disposable materials such as blood bag, transfusion set, in-line leukocyte filter system, and plasma virus-inactivation system, it is jontly invested by Suzhou Qitian Transfusion Technology Co., Ltd., Shanghai Blood Center, and U.S. Rare Antibody Antigen System Co., Ltd. In China, LAISHI developed the first flexible, disposable container for blood collection, eliminating complications associated with glass containers and allowing blood to be separated into therapeutic components. Since then, LAISHI has continued to develop safe, disposable, user-friendly, and state-of-the-art medical devices such as in-line leukocyte filter system, and plasma virus-inactivation system. LAISHI has 72 staffs, including 14 high and middle level engineers, assistant engineers and technicians specialized in pharmaceutical, chemical, mechanical, electrical and etc,. The company has fix assets of more than 15 million RMB(USD2,300,000). The plant covers almost 14,500 square meters, including a purify workshop of 1,500 square meters and a central laboratory. The company has series of advanced equipment in PVC granule, injection molding, extrusion, filming, welding, insertion, water preparing, drug dosage, filling and sterilization. Fifty years rich experience and a group of professional technical, as well as the advanced manufacture and research facilities and laboratory, all these make LAISHI becoming a domestic pioneer and leader in the development and manufacture of disposable products that improve the safety and availability of blood. We have got Drug GMP Certification, ISO9001, ISO13485 Quality Certification and the products are CE(0197) certified as well. 1
2 Established in the year of 1994, Shanghai Science & Technology Imp. & Exp. Co., Ltd. is the salesbranch of for Fosun/Foshion/Laishi/Meiyi brand disposable medical supplies like blood bags, Transfustion sets, surgical sutures, blades, scalpels, uringe drainage bags which are manufactured by our own factory and also some other relative disposable medical supplies like oxygen masks, syringe sets, infusitons sets, hospital trolleys, patient monitors which are manufactured by our afiliated factories. Shanghai Science & Technology Imp. & Exp. Co., Ltd. is becoming a comprehensive disposable medical supplies in medical supplies industry. Water Preparation Line Semi-auto Bag Welding Equipments Part of Production Line 2
3 Mould Equipments Film Extrusion Equipments Steam Sterilization Equipments Quality Control Department and Laboratory 3
4 PRODUCTS INTRODUCTION: BLOOD BAG Disposable plastic blood bag mainly and for separation, compose collection bag, satellite bags and preservation and relevant anticoagulant. Single blood bag is transfusion of red used for collection, preservation and blood cell, plasma transfusion of whole blood. Multi-blood bag and platelet. is mainly used for collecting whole blood IN-LINE LEUKOCYTE FILTER SYSTEM Disposable blood bag with integrated WBC and reducing filters is designed for preparing blood components without leukocyte in blood bank implant-anti-host and virus-infected or blood center. Its primary function is for diseases from reducing the white blood cells in whole non-self s white blood or red blood cell concentrates, preventing lots of ill-reaction in transfusion blood cells. PLASMA VIRUS-INACTIVATION SYSTEM Plasma is a blood component of large clinical demand with high virus risk. The reliable way of preventing and reducing the such as prions, on a single unit of plasma, especially transfusion-associated virus infection is to better effect on inactive the virus in plasma. Methylene blue HBV, HCV, and (MB) photo-inactivation of plasma is a HIV. method that effectively removes any intracellular potentially infectious agent, General Features Designed for collection, storage, transfusion and transportation of human blood and its components. Manufactured from high quality medical grade plasticized PVC compatible with blood having properties such as low toxicity, transparency, flexibility, high tensile strength, heat and cold resistance and acceptable permeability to water, oxygen and carbon dioxide. Consists of a single or multiple bags connected with tubes, needles, needle covers and clamps. Ultra-thin walled 16G Venipuncture needle is optimal for reducing donor pain. Soft twist-off needle cover that provides excellent tamper-evidence and a finger-contoured hub that incorporates a "bevel-up" indicator. 4
5 Highly flexible and kink-resistant blood collecting tube includes serial numbers for precise, easy identification Rounded corners minimize the volume of blood lost in processing The breakaway closures (BAC) are designed for quick and easy opening of the fluid paths between bags. Easy to break off the valve allows plasma transfer to both directions freely Safe and easy-to-open out-let port design provides protection from contamination High quality, peel-resistant label provides for convenient writing. Anticoagulant solutions used are CPD for blood storage up to 21 days and CPDA-1 for enhanced storage up to 35 days. Optional CPD-SAGM anticoagulant solution variant for red blood storage up to 35 days. Dual packaging (Individual & Aluminum) eliminates microbial contamination on the surface and maintains the content of anticoagulant. Sterilized by steam in high pressure can assure products non-pyrogen and toxin-free. Extrusion type and roll welding type blood bags can satisfy different costumers requests. Anticoagulant solutions used in Blood Bag Whole Solution Purpose blood/red cell Storage Additive Concentrations (per 100ml) Performance Period Citric Acid (Anhydrous) g Prevent coagulation of blood CPD Anticoagul ation and storage of blood 21 days Sodium Citrate (Dihydrate) 2.63 g Adjust ph MonobasicSodium Phosphate (Monohydrate) g Nutrition source for red cell Dextrose (Monohydrate) 2.55 g Supports ATP production Water for injection q.s. 100 ml Citric Acid (Anhydrous) g Prevent coagulation of blood CPDA 1 Anticoagul ation and storage of blood 35 days Sodium Citrate (Dihydrate) 2.63 g Adjust ph MonobasicSodium Phosphate (Monohydrate) g Nutrition source for red cells Dextrose (Monohydrate) 3.19 g Support ATP production Adenine g Supports to maintain ATP level Water for injection q.s. 100 ml in red cell Dextrose (monohydrate) g Nutrition source for red cells SAGM Red cell preservatio n 35 days Sodium chloride g Adjusts osmotic pressure Adenine g Supports to maintain ATP level D-mannitol g in red cell Water for injection q.s. 100 ml Supports integrity of red cell membrane (to avoid haemolysis) 5
6 Specification of Each Model 1. SINGLE BLOOD BAG SYSTEM Consists of one plasticized PVC bag containing anticoagulant solution Designed for collecting and storage of whole human blood Bag Capacity (ml) Needle Anticoagulant Gauge Type Quantity Pouch/Carton G CPDA/CPDA-1 14ml 5/ G CPDA/CPDA-1 35ml 5/ G CPDA/CPDA-1 49ml 5/ G CPDA/CPDA-1 63ml 5/90 2 DOUBLE BLOOD BAG SYSTEM Consists of 1 Primary whole blood collection bag containing anticoagulant solution and one Satellite bag Used for separation and storage of two components from whole human blood wihin a sterile closed environment Distributes whole blood into two parts after centrifugation: 1) Packed Red Cell, 2) Plasma Bag Capacity(ml) Primary/Satellite Needle Anticoagulant Gauge Type Quantity Pouch/Carton 350/300 16G CPDA/CPDA-1 49ml 4/72 450/400 16G CPDA/CPDA-1 63ml 4/72 3 TRIPLE BLOOD BAG SYSTEM Consists of 1 Primary whole blood collection bag containing anticoagulant solution and 2 Satellite bags Used for separation and storage of three components from whole human blood within a sterile closed environment Distributes whole blood into three parts after centrifugation: 1) Packed Red Cell, 2) Plasma, 3) Platelets Bag Capacity(ml) Needle Anticoagulant Primary/Satellite Gauge Type Quantity Pouch/Carton 350/300*2 16G CPDA/CPDA-1 49ml 3/45 450/400*2 16G CPDA/CPDA-1 63ml 3/45 350/300*2 16G CPD-SAGM 49/80ml 3/36 450/400*2 16G CPD-SAGM 63/100ml 3/36 6
7 4 QUADRUPLE BLOOD BAG SYSTEM Consists of 1 Primary whole blood collection bag containing anticoagulant solution and 3 Satellite bags Used for separation and storage of four components from whole human blood within a sterile closed environment Distributes whole blood into four parts after centrifugation: 1) Packed Red Cell, 2) Plasma, 3) Platelets, 4)Cryoprecipitate Bag Capacity(ml) Needle Anticoagulant Primary/Satellite Gauge Type Quantity Pouch/Carton 350/300*3 16G CPDA/CPD A-1 49ml 3/45 450/400*3 16G CPDA/CPD A-1 63ml 3/45 350/300*3 16G CPD-SAGM 49/80ml 3/36 450/400*3 16G CPD-SAGM 63/100ml 3/36 TRANSFER BAG Used for collection and storage of any one of the blood components. Can be used in place of satellite bag. With or without spike. Bag Capacity(ml) Transfer Spike Pouch/Carton / with or 10/ without 10/ /150 OPTIONAL COMPONENTS Needle Protector Sampling Port Anti-needle stick protector prevents accidental needle stick injuries by covering donor needle after removal of venipuncture. Sampling needle with pre-attached vacuum tube holder facilitates required blood sampling. Sampling Pouch Platelet Storage Bag Sampling pouch is available to collect the first blood flow from the donor in order to prevent from contamination indigenous. Platelet storage bag that is transparent, flexible and gas permeable, is designed to maintain acceptable ph over the components 5-day shelf life. 7
8 CERTIFICATE OF ISO, CE, GMP, FSC Blood bag Manufacturer s Add: Suzhou Laishi Transfusion Equipment Co.,ltd. Add: Changsheng Road, Tongli Town, Wujiand, Jiangsu, Pr. Of China Phone: , Fax : Sales Office: Shanghai Science & Technology Imp/Exp Co.,ltd. Add: Floor 4, Building 9, Section B, No. 449 Nujiang Road(North), Shanghai, China Tel: , _8008 Fax: Mail: info@fosunmedical.com 8
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