Comprehensive Stool Analysis / Parasitology x2

Transcription

1 Patient Details: ample eport W3 2J ample eceived: 09/01/2003 Date Of eport: 23/06/2003 Practitioner Details: I W D L Individual Wellbeing Diagnostic Laboratories W3 2J Lab ef No: Patients DOB: 07/09/1952 Comprehensive tool Analysis / Parasitology x CULTUE WITH ENITIVITY (CN) Bacteriology Culture Beneficial flora Imbalances Dysbiotic flora Bifidobacter 2+ Gamma strep 3+ Klebsiella pneumoniae 4+ E.coli 4+ Grp B beta trep 2+ Lactobacillus 3+ Normal flora No yeast isolated Mycology (Yeast) Culture Dysbiotic flora PAAITOLOGY ample 1 ample 2 Many Blastocystis hominis are Yeast Few Pollen Many Blastocystis hominis Few Pollen Giardia lamblia Cryptosporidium Comments: Beneficial flora are normal inhabitants of the intestinal tract, and their presence in the amount of 3+ to 4+ is vital for proper metabolic function. ome of their responsibilities include aiding in digestion and vitamin synthesis, eliminating toxins, and preventing the formation of pro-carcinogens. Altered gut ecology resulting from imbalanced flora, dysbiotic flora, and yeast overgrowth may have far reaching effects. These organisms have repeatedly been associated with mild to moderate intestinal disorders, and have been linked to systemic and auto-immune disorders through the production of endotoxins and their role in creating altered intestinal permeability. PAAITOLOGY: Intestinal parasites, usually transmitted through contaminated food and water sources, are never normal inhabitants of the intestinal tract. Intestinal parasites pose serious health risks to the elderly and immuno-compromised, and are also known causative agents of many intestinal disorders.

2 DIGETIVE PAAMETE Chymotrypsin Triglycerides Muscle fibers Vegetable fibers 22 >9.0 IU/g 439 <300 mg/dl hpf 0-4 hpf Fecal chymotrypsin is a useful measure of proteolytic activity and is closely correlated with protein digestion. Decreased chymotrypsin values may reflect pancreatic insufficiency. Triglycerides are the primary form of dietary fats and oils. Elevated triglycerides indicates reduced fat hydrolysis by pancreatic lipase. Elevated meat and/or vegetable fibers are indicative of incomplete digestion. This may be due to hypochlorhydria, pancreatic insufficiency, or improper mastication. ABOPTION PAAMETE Cholesterol Carbohydrates teatocrit % 96 < 250 mg/dl % Movement of hydrolyzed carbohydrates across the brush border and the basolateral membrane constitute important steps in the absorption process. The amount of fecal carbohydrates is a measure of carbohydrates that are unable to successfully cross into the circulation. teatocrit is a sensitive and specific test for fat malabsorption. Elevated levels of cholesterol may also be an indication of fat malabsorption, and should be considered in conjunction with levels of carbohydrate and fat in the feces for an assessment of absorptive function. INFLAMMATOY MAKE Lysozyme Lactoferrin ng/ml Lysozyme is derived from granulocytes, monocytes and macrophages. tudies have shown fecal lysozyme concentrations to be elevated in colonic Crohn s disease and ulcerative colitis. Lactoferrin, a neutrophil-derived protein, has proven to be a reliable measure of inflammatory processes in the intestine, often attributed to bacterial infections. IMMUNOLOGY MAKE Fecal siga ng/ml Immunological activity in the gastrointestinal tract can be assessed using secretory IgA measurements. siga plays an important role in controlling the intestinal milieu, which is constantly presented with potentially harmful antigens such as pathogenic microorganisms, abnormal cell antigens, and allergenic protiens. Additional lab comments:

3 INFECTIOU PATHOGEN: EIA EVALUATION Enterohemorrahgic E. coli cytotoxin Campylobacter BC ph WBC - are Yeast (microscopic) are Mucus ative Occult blood Pos ative % Acetate % Propionate % Butyrate % Valerate BIOCHEMICAL ANALYI: CFA BEAKDOWN 0% 25% 50% 75% 100% eference ange 54-67% 16-24% 14-23% 3-13 % n-butyrate ug/gm Comments: INFECTIOU PATHOGEN: EIA evaluations for organisms most commonly classified as pathogens. Classic symptoms range from diarrhea with abdominal pain to nausea, cramps, distension, heartburn, headaches, weight loss, bloating and belching. Acute cases may be accompanied by vomiting, fever, chills, bloody stools and fatigue. Additionally, H. Pylori is known to be a causative agent of gastritis and peptic ulcer disease. tudies show that CFA play many roles in gut physiology and GI health. They have demonstrated the potential to improve the microcirculation in the intestinal mucosa, reduce the number of some pathogenic bacteria, decrease inflammation, and contribute to normal cell metabolism and differentiation.

4 BACTEIAL ENITIVITY Klebsiella pneumoniae Prescriptive agents ensitive Intermediate esistant Augmentin Cefpodoxime Cefuroxime Ciprofloxacin Tetracycline Trimeth-ulfa Natural agents ensitive Intermediate esistant Berberine Black Walnut Caprylic acid Cats Claw Goldenseal Oregano Uva Ursi Mastic gum

5 Patient Details: ample eport W3 2J ample eceived: 09/01/2003 Date Of eport: 23/06/2003 Practitioner Details: I W D L Individual Wellbeing Diagnostic Laboratories W3 2J Lab ef No: Patients DOB: 07/09/1952 Klebsiella Potential opportunistic pathogen: possibly as a consequence of multiple antibiotic resistance. Member of the family Enterobacteriaceae. Is closely related to the genera Enterobacter and erratia. May be isolated in small numbers in many healthy individuals. K. pneumoniae has been implicated as a cause of diarrhoea, and some strains are enterotoxigenic. The elaborated toxin leads to an increase in cgmp which changes the electric state of the mucosa. Listed as a "possible pathogen" in the amount of ymptoms: Commonly asymptomatic, though may cause diarrhea (K. pneumoniae, in particular). Infection has been linked to ankylosing spondylitis as well as myasthenia gravis (antigenic cross-reactivity), and these patients usually carry larger numbers of the organism in their intestines than healthy individuals. Extraintestinal infection typically involves the respiratory or urinary tracts, but may infect other areas as well. These infections are often indistinguishable from those of E. coli. Found in: The gut is the main reservoir of opportunistic strains. Has been isolated from foods and various environmental sources. Treatments: Antimicrobial therapy is often unnecessary. Where needed, Klebsiella is often sensitive to cephalosporins, gentamycin, ikanamycin, chloramphenicol, and polymyxin B or colistin. Tetracycline or doxycycline may be used. Does not respond to penicillin. Klebsiella thrives on a diet high in starch, so a low-starch diet may be helpful. Natural substances include grapefruit seed extract, garlic, black walnut, pau d'arco, aloe vera, oregano, clove, cinnamon, thyme.

6 Patient Details: ample eport W3 2J ample eceived: 09/01/2003 Date Of eport: 23/06/2003 Practitioner Details: I W D L Individual Wellbeing Diagnostic Laboratories W3 2J Lab ef No: Patients DOB: 07/09/1952 Blastocystis Amoeba - Originally considered a yeast, but has been reclassified as an amoeba. pathogenic: Its pathogenicity has been controversial, but is now being strongly considered as a pathogen. Anaerobic, but contains hundreds of mitochondria devoid of enzymes. Has no cyst form. Mainly inhabits the cecum and colon. Common parasite showing up in ~15% of patients. ymptoms May be asymptomatic. May cause mild to moderate diarrhea or constipation, colicky abdominal pain, gas, nausea, vomiting, and fever. Has been associated with reactive arthritis, as well as chronic fatigue or other symptoms more commonly seen in Candida elated Complex, e.g. sleeplessness, inability to work, lassitude, dizziness. Occational pruritis. Blood, mucus, or WBC's may occasionally be isolated from the stool. Found in: Probable fecal/oral spread, including contaminated food and water. More common in crowded living conditions, malnutrition, poor hygiene. Greater prevalence in tropical countries than the UK. ome transmission via immigrants from other countries, but not enough to reflect the overall incidence. Infection has been associated with travel. Much remains to be learned about the epidemiology. Treatments: Treatment controversial. Metronidazole (Flagyl) (750 mg tid x l0 d) or iodoquinol (650 mg tid x 20 d) have been reported to be effective. Emetine, furazolidone, trimethoprim-sulfamethoxazole, and pentamidine have been used. Tetracycline has been given to remove bacteria essential to B. hominis survival. Entero-vioform is highly effective, but banned in U.. due to neuropathies. Various herbs may be effective, including oil of oregano. A weakened intestinal mucosa may predispose individuals to suffer the harmful effects of B. hominis. B. hominis is a significant problem in AID and other immunosuppressed patients. Fatal infections have been encountered in monkeys. equires the presence of bacteria for optimal growth. Difficult to rid of (7 different stages). Botanicals usually not strong enough.