Table of Contents. Founder Speaks. Founder Speaks. Where innovation is a tradition. 05 Our Facilities. 06 Research & Development

Transcription

1 Sami Sabinsa Group Worldwide No 1904, Aspect Tower, POBox 9978, Business Bay, Dubai, United Arab Emirates Tel: Fax: infor@samidirectae wwwsamidirectae

2 03 Table of Contents Founder Speaks Founder Speaks 03 Where innovation is a tradition 05 Our Facilities 06 Research & Development 08 Intellectual Properties 10 Recognition - The proof of excellence 16 Corporate Social Responsibility 18 About Sami Direct 20 Be a Part 22 Dear Friend, Congratulations on your decision! A little over 4 decades ago, I went from a small town of South India to the United States of America seeking fulfillment of my dreams Today, with a business conglomerate spread across the world, I can confidently say that the future belongs to those who believe in the beauty of their dreams The aspiration to dream and the conviction to follow their dreams is what sets apart the extraordinary from the ordinary Congratulations for choosing to be among the extraordinary Now we are in it together You have chosen the right place and the right means The awesome combination of extensively researched products and a revolutionary business plan is a definite formula for success Believe me, making money has never been such fun! We are with you at every step to help you fulfill your dreams and reach greater heights Welcome again, Dr Muhammed Majeed

3 04 05 Innovating for the Future from the Past Where In Nature lies the power to heal and to protect A truth that our ancestors had known and practiced centuries ago has only now come to the understanding of the modern generation Sami was born out of this realization, and exists for the sole purpose of bringing the healing power of Nature to cure and nurture human life Dr Muhammed Majeed is the inspiration and motivation behind Sami and the Sabinsa Group of Companies Dr Majeed has a PhD in Industrial Pharmacy After a decade and half of working with respected names in the American pharmaceutical industry, Dr Majeed first set up Sabinsa Corporation in New Jersey, USA in 1988 He later set up Sami Labs Limited Bangalore, India in 1991, with the vision of research, development and marketing of a new genre of products natural therapeutics TM The miraculous properties of nature can be fully extracted only through innovative use of scientific technology Thus, based on market-oriented research, the company integrates modern scientific techniques with ancient wisdom of Ayurvedic herbal armamentariums to produce new drug molecules health solutions that have brought back smiles to millions of faces around the world As one of the world's largest health science company, the Sami Group has a responsibility towards the people Through innovative research, deep understanding of the market and production excellence, Sami Labs Ltd will provide consumers with the best of natural product solutions for a healthier and wealthier life Innovation is a Tradition Over the past three decades, the organization has grown into a health science multinational with presence in USA, Europe, India, Japan, Australia, China, UAE, South Africa and Brazil It employs over a 1000 people with six manufacturing locations in India and one in USA Its research facility in Bangalore has over a hundred scientists involved in specialized work in the areas of phytochemistry, organic chemistry, biochemistry, tissue culture and plant biotechnology Today, Sami holds a strong intellectual property portfolio with several US and international patents to its credit apart from awards and recognitions worldwide

4 06 07 Our Facilities Sabinsa Manufacturing, Utah, USA R&D Center and Corporate Office, Bangalore, India Solid foundation for our dreams The main active ingredients in all Sami Direct nutraceutical and cosmeceutical products are standardized herbal extracts These extracts are manufactured in the various state of the art Sami Sabinsa manufacturing facilities Sami Sabinsa manufacturing facilities are currently split across 7 different sites - one in Utah USA,four in Bangalore and two in Hyderabad, India The company is continuously looking at expanding its production facility to address the increasing market demand As we expand around the world, we want to make sure that any new manufacturing facilities we build comply with our forward thinking principles and practices Biotechnology Facility, Nelamangala, India All our sites adhere to strict controls, and are subject to third party audits and government regulations This isn't just about following rules It's about working to the standards we set ourselves and being true to our values Super Critical Fluid Extraction (SCFE), Nelamangala, Bangalore, India Continuous Extraction, Dobaspet, Bangalore, India Standardized Extraction of diverse Phytonutrients, Kunigal, Bangalore, India Finished Dosage Forms, Sabinsa Manufacturing Utah, USA Phytonutrient Standardized Extraction, Genome valley, Hyderabad, India

5 08 09 Research & Development Biological Research Division Bio research division is a NABL accredited division focused on developing the safety & efficacy profile of the products by screening through an elaborate series of in vitro methods that does not involve testing on animals Finding new light Recognized by the Department of Scientific and Industrial Research, Sami R&D is a multi-disciplinary division pursuing diverse fields of research The R&D also works closely with the Government of India and the Indian Pharmacopoeia Committee on preparation of Standard Operating Procedures for Ayurvedic herbs and monographs for Indian herbs Equipped with the best of talent and facilities, Sami research is geared to constantly innovate and sustain high quality output to broaden the product portfolio, enrich its intellectual property and build up a robust pipeline of products Natural Drug Division The scientist in this division focuses on identifying, isolating and developing drugs from various natural source having a potential to become a drug Phytochemistry The scientist in this team especially focus on developing standardized Phytoextracts that function as nutraceuticals, cosmeceuticals or nutricosmetics and help to skilfully commercialize them into finished products that meet ever increasing global needs Analytical R&D Analytical R&D has been audited and NABL accredited for its validated testing protocolsequipped with the state of art facility to meet international standards, this division plays a pivotal role in setting the product standards and ensuring the adherence to these set qualities Formulations R&D The Formulations R&D division forms the convergence of the various product concepts that have been developed as ingredients Bioactives, based on their activity and functionality, are molded into various forms with Nutraceutical, Cosmeceutical, Nutricosmetic as well as Food & Beverage applications Biotechnology Biotechnology Division has developed stable probiotics and enzyme complexes Experiments on biocatalytic conversion to enhance better recovery of certain bioactives are carried out here Tissue Culture Synthetic Chemistry Synthesis of a novel compound is a problem solving task, where a synthesis is designed for a target molecule by selecting optimal reactions from optimal starting materials Development of new reactions and methodologies for the efficient synthesis of bioactive molecules The scientists here develop high-yielding varieties of medicinal plants & multiply them through tissue culture techniques in the laboratory

6 10 11 Intellectual Intellectual Title Patent No Brand /Ingredient Properties 14 Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives US 6,849,645 Cosmoperine (THP) 15 Process for preparing water soluble diterpenes and their applications US 6,960, Composition and methods containing bioavailable Se-methyl-L- Selenochysteine for human and veterinary use US 6,982,273 Methyselene 127 International patents and still growing A convenient process of manufacture for Difluromethylornithine and related compounds A convenient process of manufacture for Difluromethylornithine and related compounds US 6,998,502 US 7,345,196 Efflornithine Efflornithine US PATENTS Title Patent No Brand /Ingredient Use of Piperine to increase bioavailability of nutritional compounds Use of Piperine as a bioavailability enhancer Potassium hydroxycitrate for the suppression of appetite and induction of weight loss Method of preparing a Forskolin composition from Forskolin extract and use of Forskolin for promoting lean body mass and treating mood disorders US 5,536,506 US 5,744,161 US 5,783,603 US 5,804,596 BioPerine BioPerine Citrin K ForsLean Compositions and methods containing Allium Sativum Linn, (Garlic) naturally enriched with organic selenium compounds for nutritional supplementation Bioavailable compositions of Natural and Synthetic HCA Compositions and methods containing natural compounds from non-conventional sources that are useful in maintaining normal blood sugar levels Convenient stable non-hygroscopic crystalline solid forms of racemic and chiral LA-plus salts process for their manufacture and uses Commercially viable process for high purity of fatty alcohol C24 to C36 and its cosmetic application for skin hair and nails Process for the synthesis of biologically active oxygenated compounds by dealkylation of the corresponding alkylethers US 7,014,874 US 7,063,861 US 7,160,562 US 7,202,270 US 7,217,546 US 7,253,324 SelenoForce GarCitrin Metformin-Like Compounds Liposol Policosanol Stilbenes 05 Bioprotectant composition, method of use and extraction process of Curcuminoids US 5,861,415 Curcumin C3 Complex 25 Method of preparation and use of coconut water in mammalian tissue nourishment, growth, and healthy maintenance US 7,300,682 Cococin Use of Piperine as a bioavailability enhancer Process for making high purity piperine for nutritional use Composition and method containing products extracted from Commiphora Sp for prevention and treatment of abnormal cell growth and proliferation in inflammation, neoplasia and cardiovascular disease Composition and methods containing an antimicrobial essential oil extracted from Coleus Forskohlii Cross regulin composition of turmeric-derived Tetrahydrocurcuminoids for skin lightening and protection against UVB rays US 5,972,382 US 6,054,585 US 6,436,991 US 6,607,712 US 6,653,327 BioPerine BioPerine Gugulipid Coleus Oil Tetrahydrocurcuminoids New Chemical entities with multiple modes of anti-inflammatory action New Chemical entities with multiple modes of anti-inflammatory action Process for the Manufacture of Chiral And Racemic Forms of 3- Aminotetrahydrofurans, their Salts and Derivatives Non-cytotoxic synthetic analogues of (1E, 6E )-1,7-Bis (4 hydroxy- 3-methoxyphenyl)-1,6-heptadiene-3, 5-dione and therapeutic applications thereof in cystic fibrosis) C o m p o s i t i o n a n d m ethods fo r t h e m a n a gement o f hyperproliferative dermatological conditions US 7,371,889 US 7,378,442 US 7,514,573 US 7,521,580 US 7,582,314 AKBBA+NSAIDS AKBBA+NSAIDS 3-Aminotetrahydrofurans Curcuminoid analogs Boswellin 11 Process of obtaining composition of stable lutein and lutein derivatives US 6,689,400 ZeaLutein 31 Hydro-alkoxyl citronellal compounds synthetic routes, compositions and uses thereof US 7,842,842 Woody odorants Process for the production of potassium hydroxy citric acid and compositions containing the potassium hydroxy citric acid Manufacturing processes for Se-alkylselenocysteine, Se-allylselenocysteine, Se-arylselenocysteine US 6,770,782 US 6,794,537 Citrin K Methyselene Dipeptides incorporating selenoamino acids with enhanced bioavailability synthesis, pharmaceutical and cosmeceutical applications thereof Treatment of superficial and cutaneous mycoses with a pure form of 1,7-bis(4-hydroxy-3-methoxyphe nyl)-3,5-heptanedione US 8,003,614 US 8,119,696 Msc-dipeptide synthetic route Tetrapure

7 12 13 Title Patent No Brand /Ingredient Intellectual 34 Dipeptides incorporating selenoamino acids with enhanced bioavailability synthesis, pharmaceutical and cosmeceutical applications thereof US 8,193,156 Lsm-dipeptide synthetic route Intellectual Properties 35 Protective compositions for dermal papilla cells US 8,247, 003 Saberry -Cococin Preservative system for cosmetic formulations compositions and methods thereof Compositions and its use in treating obesity or inducing weight loss Peptides modified with triterpenoids and small organic molecules: synthesis and use in cosmeceuticals Inotilone derivatives as coherent biological response modifier (cbmr) Novel synthesis of 4-aryl 4-acyl piperidine, its salts and analogs using indium metal US 8,329,095 US 8,329,743 US 8,383, 594 US 8,394,852 US 8,853,407 SabiLize Anti-obesity formulation Olepent Inotilone derivatives 41 Anti-obesity potential of calebin a US 8,933,121 Calebinoids 42 Oleanoyl peptide composition and method of treating skin aging Synthesis of 4-aryl 4-acyl piperidine, its salts and analogs using indium metal Orally bioavailable stilbenoids-compositions and therapeutic applications thereof Orally bioavailable stilbenoids-compositions and therapeutic applications thereof Orally bioavailable stilbenoids-compositions and therapeutic applications thereof Composition and method for the protection of articular cartilage Anti-obesity potential of calebin a Synthesis of calebin-a and its biologically active analogs US 8,987,212 US 9,029, 547 US 9,029, 424 US 9,050,284 US 9,056,074 US 9,220,703 US 9,328,330 US 9,365,486 Pharmaceutical intermediates Olepent Pharmaceutical intermediates 3-hydoxypterostilbene 3-hydroxypterostilbene 3-hydroxypterostilbene Calebin Calebin Calebin INTERNATIONAL PATENTS Title Patent No Brand /Ingredient 01 Use of tetrahydrocurcuminoids to regulate physiological and AU Curcumin C3 Reduct pathological events in the skin and mucosa 02 Bioavailable composition of natural and synthetic HCA AU Garcitrin 03 Compositions and methods for the management of hyperproliferative dermatological conditions AU Boswellin PS 04 Compositions containing allium sativum linn (garlic) naturally enriched with organic selenium compounds for nutritional supplementation AU Selenoforce 05 Process for preparing water soluble diterpenes and their applications AU Antiobesity potential of calebin a (109) AU Calebin 07 Hepatoprotectant activity of garcinol (113) Au Garcinol 08 Use of piperine as a bioavailability enhancer CA BioPerine 09 Forskolin for promoting lean body mass CA TM ForsLean 10 Process for preparing water-soluble medicaments comprising CA complexation of forskolin in cyclodextrins Composition comprising scirpusin a and scirpusin b and antiobesity potential thereof Process for the manufacture of 3'-hydroxy pterostilbene Synergistic selenopeptide formulations for the protection of dermal papilla cells US 9,387,193 US 9,458,075 US 9,498,423 Cyperus 3-hydroxypterostilbene Amla Cococin se peptide 11 Anti-obesity potential of Calebin A CA Calebinoids 12 Composition for down-regulating pro-inflammatory markers I PolyBos 13 Method of solubilising forskolin and isoforskolin in water and clear Ocufors aqueous solution comprising the same 14 Process for preparing water soluble diterpenes and their applications HK Process for preparing water soluble diterpenes and their applications CN Compositions and methods for the management of Boswellin PS hyperproliferative dermatological conditions 17 Anti-obesity potential of calebin a ( Calebin 18 Melanogenesis inhibition by 3,5-dimethoxy-4'-hydroxypterostilbenes PteroWhite and cosmeceutical applications thereof

8 14 15 Title Patent No Brand /Ingredient Title Patent No Brand /Ingredient 19 Use of piperine as a bioavailability enhancer EP BioPerine Bioprotectant composition, method of use and extraction process of curcuminoids Coconut water and its method of preparation Process of making and method of use of tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa cells Bioavailable composition of natural and synthetic HCA Use of tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa Forskolin for promoting? Lean Body Mass Compositions containing Allium Sativum Linn (garlic) naturally enriched with organic Selenium compounds for nutritional supplementation Process for preparing water soluble Diterpenes and their applications Compositions and methods for the management of Hyperproliferative Dermatological conditions Hepatoprotectant activity of Garcinol Protective compositions for Dermal Papilla Cells Method for the treatment of Hypercholesterolemia A method for Solubilizing Forskolin and a composition Thereofa Process of preparing a Synergistic composition for treating Hyperproliferative Dermatological conditions A process for obtaining high purity fatty alcohols Use of Piperine as a Bioavailability Enhancer Process of obtaining compositions of stable Lutein and Lutein Derivatives Method of increased Bioavailability of nutrients and pharmaceutical preparations with Tetrahydropiperine and its analogues and derivatives Bio-available compositions of natural and synthetic Hca Compositions and methods for the management of Hyperproliferative Dermatological conditions Process for preparing water soluble Diterpenes and their applications Hepatoprotectant activity of Garcinol Process for preparing water soluble Diterpenes and their applications Composition for down-regulating Proinflammatory markers Composition for Physiological increase of male and female hormones with Diterpene Forskolin and its derivatives EP EP EP EP EP EP EP EP EP EP EP EP IN IN IN JP JP JP JP JP JP JP MX MX NZ Curcumin C3 Complex TM Cococin Curcumin C3 Reduct Garcitrin Curcumin C3 Reduct TM ForsLean Selenoforce Boswellin PS Garcinol Saberry Calebin Boswellin PS Policosanol BioPerine Xenogard Cosmoperine Garcitrin Boswellin PS Garcinol PolyBos Forskolin 45 Compositions and methods for the management of NZ Boswellin PS hyperproliferative dermatological conditions Commercial process for making forskolin and its derivatives Process for preparing water soluble diterpenes and their applications Bioavailable composition of natural and synthetic hca Use of tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa Compositions containing allium sativum linn (garlic) naturally enriched with organic selenium compounds for nutritional supplementation Protective compositions for dermal papilla cells Synergistic selenopeptide formulations for the protection of dermal papilla cells Method for the treatment of hypercholesterolemia Hepatoprotectant activity of garcinol Antiobesity potential of calebin A Synthesis of calebin-a and its biologically active analogs Compositions and methods for the management of hyperproliferative dermatological conditions Anti-obesity potential of calebin A Hepatoprotectant activity of garcinol Process for preparing water soluble diterpenes and their applications Compositions and methods for the management of hyperproliferative dermatological conditions Composition and methods for the management of hyperproliferative dermatological conditions Process for preparing water soluble diterpenes and their applications Anti-obesity potential of calebin A Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives Process for preparing water soluble diterpenes and their applications Process for preparing water soluble diterpenes and their applications Protective compositions for dermal papilla cells Use of a composition for down-regulating/inhibiting Process for preparing water soluble diterpenes and their applications Compositions comprising scirpusin a and scirpusin b and anti-obesity potential thereof Synthesis of calebin-a and its biologically active analogs Method for the treatment of hypercholesterolemia Composition and method for the protection of articular cartilage Composition and method for the protection of articular cartilage NZ568A652 NZ NZ NZ NZ NZ NZ NZ NZ NZ NZ RU RU RU SG SG ZA2007/0694 ZA2006/01898 ZA2013/05918 GB Forskolin Garcitrin Curcumin C3 Reduct Selenoforce TM Saberry -Cococin TM Saberry -Cococin -se-dipeptide Calebinoids Garcinol Calebin Calebin Boswellin PS Calebinoids Garcinol Boswellin PS Boswellin PS Calebinoids Cosmoperine Saberry + Cococin Bowellin PS Cyperus Calebin Calebin Calebin Calebin

9 16 17 Recognition The proof of excellence Edison Awards Since 1987, the Edison Awards have recognized and honored some of the most innovative new products, services and business leaders in the world 2004: Dr Majeed honored with the prestigious Ellis Island Medal of Honor from National Ethnic Coalition of Organizations, USA 2008: Dr Majeed receiving the Certificate of Excellence for Exports from Federation of Indian Export Organisations : Dr Majeed receiving the National Award from (Late) Dr Shankar Dayal Sharma, President of India, awarded by Spice Board 2010: Dr Majeed received the Daniel B Stateman award for distinguished alumni from Dr David Taft at Long Island University s 121st graduation ceremony in Brooklyn 1994: Dr Majeed receiving the National Award for Quality and Innovation (Basic Drugs) from (Late) Dr Shankar Dayal Sharma, President of India The Edison Awards is an annual competition honoring excellence in new product and service development, marketing, human-centered design, and innovation The competition is open to innovative organizations across the globe The Edison Awards are focused on the innovators as much as the innovations a unique distinction in the world of award programs Award winners represent "game changing" products and services, as well as excellence and leadership in innovation around four criteria: Concept, Value, Delivery, and Impact An Edison Award represents significant value to the award winner and to the cause of innovation and highlights tementhe strong marketing value of an unbiased 3rd-party endors 2009: Sabinsa Received Thomas Alva Edison Patent Award for GarCitrin from Research & Development Council of New Jersey, USA 2005: Sabinsa Received Thomas Alva Edison Patent Award for Tetrahydropiperine from Research & Development Council of New Jersey, USA 2004: Sabinsa Received Thomas Alva Edison Patent Award for ForsLean from Research & Development Council of New Jersey, USA 2004

10 18 19 Corporate Social Responsibility Considering the importance of biodiversity of medicinal plants and to maintain the sustainability for future generations, the company has taken up a successful initiative over the last 10 years by undertaking and promoting large scale commercial cultivation of medicinal plants globally SAMI initiated almost a decade ago, medicinal plant cultivation with a handful of farmers Over the years this effort has translated into a large scale cultivation model involving more than acres and supporting thousands of farmer families Sami supports its farmers with a buy back guarantee, crop insurance, bank finance and ensures they receive a reasonable price for the produce avoiding intermediaries Today, this successful model is being replicated in Africa and South East Asia Over 40,000 acres of contract farming to grow medicinal plants & maintain the sustainability for future generations We are committed for supporting thousands of farmers and their families through contract farming

11 20 21 About Ayurveda System of Health Care Sami Direct We are a leadership-driven company whose competitive edge lies in fueling entrepreneurship through our independent Distributors and offering unique clinically relevant nutraceutical and cosmeceutical products inspired by Ayurveda Who we are What we do Why we do it We are a part of the Sami Sabinsa Group of companies For over 25 years the Sami Sabinsa have been unlocking the mystery of herbs, extracting its goodness, and gifting the world with good health We have two clear missions One to provide alternative and complementary natural products for human nutrition, well-being & beauty Second is to provide a low cost, low risk opportunity for anyone who wants to start their own health & beauty business We want to help people live a holistic healthy life through Ayurveda inspired products At the same time, the SamiDirect business opportunity has helped people from diverse socio-economic background to build their own business, discover extra income and help them fulfil their dream health In Ayurveda, regulation of diet as therapy has great importance This is because it considers human body as the product of food An individual s mental and spiritual development as well as his temperament is influenced by the quality of food consumed by him SamiDirect products are based on the philosophy & wisdom of Ayurveda to help people stay vibrant while realizing their full potential Standardized Ingredients A standardized extract is one in which the active constituent is identified & enriched from the original herbs or its various plant parts These standardized active extracts contain guaranteed amount of evaluated bio-actives SamiDirect nutraceutical and cosmeceutical products features exclusive standardized natural ingredients, carefully selected from nature and uniquely formulated to deliver effective health & beauty benefits The Science of Cosmeceuticals Hand-picked from the secrets of time-tested botanical ingredients that have evolved from pure science and scripted in many ancient texts across the world Crafted from years of meticulous research, Johara is a brand so scientifically driven, the result can only be beauty that is pure and real All Free of Parabens, Sulfate, Synthetic Dye or Formaldehyde

12 22 23 Be A Part SUPPLEMENT YOUR OWN OR YOUR FAMILY'S INCOME EARN EXTRA POCKET MONEY TO SPEND Start Your Own Business SamiDirect will give you Ayurveda inspired wellness & beauty products, our team is always available to provide you with expert training & marketing materials to build your business on your terms Whether you re looking to earn some part-time income or grow your business as a full time career, SamiDirect offers you one of the best business opportunity The SamiDirect Business opportunity appeals to a wide range of people due to its flexibility FLEXIBLE TO HELP YOU BALANCE YOUR FAMILY COMMITMENTS BE AMBITIOUS & CHOOSE IT AS A FULL TIME CAREER Earn retail profit through exclusive products Our aim is to provide you with innovative products that you will be proud to represent and share with others products that are Ayurveda inspired and clinically researched to support in holistic wellness and beauty We refer to learning from the ancient Ayurveda texts and validate it through the latest medical and scientific literature for advances in safe, natural, active ingredients Our 125 research scientist are dedicated to giving us products that are totally effective and safe We send out samples to hospitals and independent laboratories around the world for research and testing As you begin to understand how incredibly relevant & innovative our products really are, the more you will want to recommend them to others Sharing the products is the key to your success Your income will be directly related to your efforts in sharing and selling the products, the opportunity, and building a sales organization RETIREMENT IS JUST THE BEGINNING BUILD NEW ENERGY WITH A NEW BUSINESS Financial rewards With the SamiDirect Business opportunity there is no limit to how much you can earn You re in control of how much money you make You set your own goals on your own schedule The rewards depend only on your effort, hard work and ability The SamiDirect Business opportunity Plan is one of the most competitive compensation plans in the industry Our Distributors are able to generate income in through our double bonus plan, earn luxury travel rewards and many other career path achievement & recognitions You can participate in the SamiDirect Business opportunity Plan at whichever level you wish You decide whether you want to create a part-time income through retail sales or build a full-time business

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